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Journal of Occupational Rehabilitation Jun 2019Purpose There are substantial costs associated with sickness absence and struggling at work however existing services in the UK are largely restricted to those absent... (Randomized Controlled Trial)
Randomized Controlled Trial
Purpose There are substantial costs associated with sickness absence and struggling at work however existing services in the UK are largely restricted to those absent from work for greater than 6 months. This paper details the development of an early Vocational Advice Intervention (VAI) for adult primary care consulters who were struggling at work or absent due to musculoskeletal pain, and the structure and content of the training and mentoring package developed to equip the Vocational Advisors (VAs) to deliver the VAI, as part of the Study of Work and Pain (SWAP) cluster randomised trial. Methods In order to develop the intervention, we conducted a best-evidence literature review, summarised evidence from developmental studies and consulted with stakeholders. Results A novel early access, brief VAI was developed consisting of case management and stepped care (three steps), using the Psychosocial Flags Framework to identify and overcome obstacles associated with the health-work interface. Four healthcare practitioners were recruited to deliver the VAI; three physiotherapists and one nurse (all vocational advice was actually delivered by the three physiotherapists). They received training in the VA role during a 4-day course, with a refresher day 3 months later, along with monthly group mentoring sessions. Conclusions The process of development was sufficient to develop the VAI and associated training package. The evidence underpinning the VAI was drawn from an international perspective and key components of the VAI have the potential to be applied to other settings or countries, although this has yet to be tested.
Topics: Adult; Case Management; Employment; Humans; Musculoskeletal Pain; Rehabilitation, Vocational; Vocational Guidance
PubMed: 29982957
DOI: 10.1007/s10926-018-9799-1 -
Journal of Occupational Rehabilitation Jun 2021Purpose The present study aimed to understand the roles, effective strategies and facilitators, and challenges of employment support specialists (ESS) in assisting young...
Purpose The present study aimed to understand the roles, effective strategies and facilitators, and challenges of employment support specialists (ESS) in assisting young people with mental health conditions (MHCs) gain and sustain employment in Singapore. Methods An interpretative qualitative design using an inductive approach was adopted for this study. Using a semi-structured interview guide, in-depth interviews were conducted with twenty ESS employed with mental health service providers or other community-based centers. Verbatim transcripts of the interviews were thematically analyzed using inductive methods. ESS were broadly classified as "any professionals providing employment-related support to people with MHCs". Results Majority of the ESS were employed at a tertiary psychiatric institute. Participants included vocational and occupational specialists, case managers and other clinical professionals. Three key themes emerged from the data: (i) descriptions of roles undertaken by the ESS depicting a wide range of services and requisite skillsets; (ii) facilitators that benefit young people with MHCs' in terms of job placement, for example, ESS' attitudes and attributes, and their clients' disposition; and (iii) challenges that deter effective job placements, such as factors pertaining to the ESS themselves, their clients, and clients' employers. Under this theme, ESS also proposed ways to improve employment opportunities of people with MHCs. Conclusions This study provided insight into a range of tasks performed and challenges faced by ESS in Singapore while assisting their clients. There is a need to address ESS' challenges and expectations in order to enhance their efficiency and aid reintegration of young people with MHCs into the workforce and the society.
Topics: Adolescent; Employment; Female; Humans; Male; Mental Disorders; Mental Health; Specialization
PubMed: 33090356
DOI: 10.1007/s10926-020-09930-x -
Disability and Rehabilitation Oct 2022The objective of this meta-analysis was to provide a quantitative synthesis of the effects of studies evaluating developmentally appropriate programs or interventions... (Meta-Analysis)
Meta-Analysis
PURPOSE
The objective of this meta-analysis was to provide a quantitative synthesis of the effects of studies evaluating developmentally appropriate programs or interventions for transition-age youth with mental health disorders.
METHODS
Studies, between January 1992 and March 2021, were included if they contained a sample population with a median age between 12 and 25 years and with a mental health disorder and described the results of health interventions addressing aspects of developmental transitions. Independent reviewers screened study texts and assessed the risk of bias. Random effects meta-analysis was used to pool data on standardized mean differences.
RESULTS
Under neurodevelopmental studies (6), the effect size of interventions measuring social outcomes was 1.00 (95% CI: -0.01 to 2.00), parental stress levels was -0.10 (95% CI:-0.74 to 0.55), autism symptoms was -0.40 (95% CI: -1.58 to 0.78), and self-determination was 0.16 (95% CI:-0.38 to 0.70). Under mental illness studies (3), the effect size of interventions measuring adolescent depressive symptoms was 0.48 (95% CI: 0.01 to 0.96) and parental depressive symptoms was 1.09 (95% CI: 0.20 to 1.97).
CONCLUSIONS
There is no effect of interventions except on parental depressive symptoms under mental illness studies. Further research with comparable outcomes and assessments is needed.Implications for rehabilitation:Interventions for youth with mental health disorders should be developmentally appropriate and incorporate elements to assist youth in multiple aspects of their lives.The following approaches should be considered in interventions: skills training, prevocational/vocational guidance, a client-centered approach, and/or an ecological/experiential approach.Intervention researchers and practitioners should incorporate similar outcome assessment tools and measures in order to allow for valid comparisons between intervention effectiveness.
Topics: Adolescent; Humans; Child; Young Adult; Adult; Mental Health; Mental Disorders; Delivery of Health Care; Outcome Assessment, Health Care
PubMed: 34455880
DOI: 10.1080/09638288.2021.1960440 -
Food Additives & Contaminants. Part A,... Jun 2022In this study, the residues of four insecticides, spirotetramat, flonicamid, thiamethoxam, and tolfenpyrad, and their metabolites, including spirotetramat-enol,...
In this study, the residues of four insecticides, spirotetramat, flonicamid, thiamethoxam, and tolfenpyrad, and their metabolites, including spirotetramat-enol, spirotetramat-mono-hydroxy, spirotetramat-keto-hydroxy, spirotetramat-enol-glucoside, 4-trifluoromethylnicotinamide, 4-trifluoromethylnicotinic acid, N-(4-trifluoromethylnicotinoyl) glycine, and clothianidin, were assessed using a single analysis method. The samples were extracted by acetonitrile, then purified by dispersive solid phase extraction and quantified using high performance liquid chromatography tandem mass spectrometry. The average recovery rate of 12 target compounds was 73.5-103.7%, the relative standard deviation was 1.1-18.3%, and the limit of quantification was 0.01-0.05 mg/kg. The results showed good linearity ( >0.99), meeting the requirements of the pesticide residue analysis. The dissipation half-lives of the four insecticides in eggplant were 3.4-14.5 days. After the last applications at 7 and 10 days, the final residues of the four insecticides in eggplant were <0.01-0.21, 0.085-0.26, <0.05-0.078, and <0.01-0.21 mg/kg, respectively. The dissipation and final residue results could provide a theoretical basis for the rational application of four insecticides in eggplant fields.HighlightsHPLC-MS/MS for simultaneous determination of four insecticides and their metabolites in eggplant fields.The dissipation dynamics and final residue of the target compounds in field eggplant were studied.Guidance for the safe use of four insecticides on eggplant.
Topics: Chromatography, Liquid; Insecticides; Pesticide Residues; Solanum melongena; Tandem Mass Spectrometry
PubMed: 35537031
DOI: 10.1080/19440049.2022.2040746 -
International Journal of Environmental... Jan 2023COVID-19 accelerated the growth of the digital economy and digital transformation across the globe. Meanwhile, it also created a higher demand for productivity in the...
COVID-19 accelerated the growth of the digital economy and digital transformation across the globe. Meanwhile, it also created a higher demand for productivity in the real economy. Hence, the correlation between the digital economy and green productivity is worth studying as COVID-19 prevention becomes the norm. The digital economy overcomes the limitations imposed by traditional factors of production on economic growth and empowers innovative R&D and resource allocation in all aspects. This study delved into the digital economy by focusing on its green value at different levels of development. The study gathered the green-productivity indices and the principal components of the digital economy for each prefecture-level city in China from 2011 to 2019 and meticulously portrayed their trends in spatial and temporal figures. Meanwhile, regression models were used to verify the mechanism through which digital-economy development influences the changes in green productivity. The results showed that: (1) a higher level of digital economy helps to increase urban green total-factor productivity (GTFP) and that the conclusions of this paper still held after potential endogeneity problems were solved through the instrumental-variables approach; (2) the digital economy will drive an increase in urban GTFP by upgrading firms' production technologies and that digital-economy development encourages green patent applications from firms; and (3) as the digital economy develops, it will also drive urban GTFP increases by removing polluting enterprises from the market and that the higher the level of digital-economy development, the greater the number and probability of polluting enterprises exiting the market. In view of this study's results, the government should increase the importance of the digital economy, strengthen the role of the digital economy in promoting urban green development, and provide more guidance on regional green development with the help of the digital economy.
Topics: Humans; Cities; COVID-19; Economic Development; Resource Allocation; China; Efficiency
PubMed: 36674198
DOI: 10.3390/ijerph20021442 -
Journal of Cancer Survivorship :... Feb 2024The St. Jude's After Completion of Therapy (ACT) Clinic was established in 1984 to address the needs of long-term survivors treated at St. Jude Children's Research... (Review)
Review
The St. Jude's After Completion of Therapy (ACT) Clinic was established in 1984 to address the needs of long-term survivors treated at St. Jude Children's Research Hospital. Survivors eligible for transfer to ACT Clinic include those treated at St. Jude who are cancer-free, 5 years from diagnosis (5 years after completion of relapse therapy), and 2 years after completion of therapy. Services provided to clinic attendees include transportation, housing, and medical care costs not covered by insurance. The clinic's mission is to improve the quality of life of survivors by facilitating their access to resources that optimize physical and emotional health, social functioning, and educational and vocational achievement. ACT evaluations are undertaken by a multidisciplinary team comprised of nurses, advanced practice providers, physicians, social workers, psychologists, and other medical subspecialists as needed. ACT interventions include the organization of a survivorship care plan/treatment summary, risk-based health screening, counseling about health risks/risk mitigation, comprehensive psychosocial assessment, assistance with care transitions, and case management for identification of local resources. The ACT Clinic offers educational opportunities to graduate medical trainees and precepts national and international visitors seeking guidance in the development of survivorship programs. The ACT Clinic also provides a robust infrastructure for research investigations that have aimed to characterize health outcomes in long-term survivors and test interventions to prevent/remediate adverse effects of childhood cancer and its therapy. Findings from research facilitated by the ACT Clinic have informed health surveillance recommendations for long-term survivors and guided interventions to promote healthy aging among this growing population. IMPLICATIONS FOR CANCER SURVIVORS: This review describes a model of care that addresses the medical and psychosocial challenges of survivorship while integrating research investigations to improve health outcomes among childhood cancer survivors.
Topics: Child; Humans; Cancer Survivors; Quality of Life; Survivors; Neoplasms; Hospitals
PubMed: 38294599
DOI: 10.1007/s11764-023-01519-6 -
The Journal of Prosthetic Dentistry Sep 2021Although contemporary analytical methods are available for application to data which exhibit a lack of equality of variances or a lack of normality in the error...
STATEMENT OF PROBLEM
Although contemporary analytical methods are available for application to data which exhibit a lack of equality of variances or a lack of normality in the error distribution, little guidance is provided for selecting the methods of data handling and analysis which best fit color difference data for stained esthetic materials.
PURPOSE
The purposes of this in vitro study were to apply information criteria of analysis of variance (ANOVA) methods of differing error distributions and covariance structures when analyzing color differences to determine the degree of alienation among 3 Commission Internationale de l'Eclairage (CIE) color difference formulae to assess the linearity of relationships among these formulae and to independently assess differences among various computer-aided design and computer-aided manufacture (CAD-CAM) materials in any color change after common forms of staining over time.
MATERIAL AND METHODS
Hybrid ceramic, resin nanoceramic, feldspathic-ceramic, and lithium-disilicate ceramic specimens (N=128) were subjected to staining from water, tea, coffee, and red wine over 1, 7, and 30 days, with color differences calculated from baseline. Akaike information criteria (AIC) and Bayesian information criteria (BIC) values were determined for Gaussian and lognormal error distributions at covariance structures of standard variance components and compound-symmetry. The analysis of variance used to analyze any significant effects on these color differences was the one with the lowest AIC and BIC values. Then, for each solution, day, and CIE color difference formula, any significant difference in the color differences between all pairs of materials was found by Bonferroni-corrected Student t tests. Those statistically significant pairwise comparisons where the larger of the color differences met or exceeded the acceptability threshold were labeled as statistically and visually noteworthy.
RESULTS
For this color difference data set, the lognormal error distribution and the covariance structure of compound symmetry provided the best AIC and BIC. Because the interaction between material, solution, and day was statistically significant (P<.001), pairwise comparisons were made between all pairs of materials for each level of solution and day studied. Noteworthy differences were identified, where hybrid ceramic and resin nanoceramic each had color changes after staining in coffee and red wine that were greater than each of feldspathic-ceramic and lithium-disilicate ceramic.
CONCLUSIONS
AIC and BIC values evaluate distinctively the Gaussian and lognormal error distributions when analyzing highly varying color differences. Although there is a high linear correlation between the 3 color difference formulae studied, each formula is unique, and each represents a different assessment of the perceived color difference. CAD-CAM materials, staining liquids, and time points affected the notable color changes.
Topics: Bayes Theorem; Ceramics; Color; Computer-Aided Design; Dental Materials; Dental Porcelain; Esthetics, Dental; Humans; Materials Testing; Surface Properties
PubMed: 32958303
DOI: 10.1016/j.prosdent.2020.08.006 -
Anatolian Journal of Cardiology Oct 2020Coronavirus disease 2019 (COVID-19) caused by 'Severe Acute Respiratory Syndrome Coronavirus-2' (SARS-CoV-2) infection emerged in Wuhan, a city of China, and spread to... (Review)
Review
Coronavirus disease 2019 (COVID-19) caused by 'Severe Acute Respiratory Syndrome Coronavirus-2' (SARS-CoV-2) infection emerged in Wuhan, a city of China, and spread to the entire planet in early 2020. The virus enters the respiratory tract cells and other tissues via ACE2 receptors. Approximately 20% of infected subjects develop severe or critical disease. A cytokine storm leads to over inflammation and thrombotic events. The most common clinical presentation in COVID-19 is pneumonia, typically characterized by bilateral, peripheral, and patchy infiltrations in the lungs. However multi-systemic involvement including peripheral thromboembolic skin lesions, central nervous, gastrointestinal, circulatory, and urinary systems are reported. The disease has a higher mortality compared to other viral agents causing pneumonia and unfortunately, no approved specific therapy, nor vaccine has yet been discovered. Several clinical trials are ongoing with hydroxychloroquine, remdesivir, favipiravir, and low molecular weight heparins. This comprehensive review aimed to summarize coagulation abnormalities reported in COVID-19, discuss the thrombosis, and inflammation-driven background of the disease, emphasize the impact of thrombotic and inflammatory processes on the progression and prognosis of COVID-19, and to provide evidence-based therapeutic guidance, especially from antithrombotic and anti-inflammatory perspectives.
Topics: Betacoronavirus; Blood Coagulation Disorders; COVID-19; Coronavirus Infections; Cytokines; Hemostatic Disorders; Humans; Immunomodulation; Inflammation; Pandemics; Pneumonia, Viral; Prognosis; SARS-CoV-2; Thrombosis
PubMed: 33001051
DOI: 10.14744/AnatolJCardiol.2020.56727 -
Nature Apr 2019
Topics: Burnout, Professional; Decision Making; Humans; Mentoring; Mentors; Morale; Professional Competence; Research Personnel; Social Support; Vocational Guidance
PubMed: 30976108
DOI: 10.1038/d41586-019-00992-3 -
Journal of Counseling Psychology Oct 2014Recent advances in the field of neuroscience have dramatically changed our understanding of brain-behavior relationships. In this article, we illustrate how neuroscience... (Review)
Review
Recent advances in the field of neuroscience have dramatically changed our understanding of brain-behavior relationships. In this article, we illustrate how neuroscience can provide a conceptual and methodological framework to understand our clients within a transdiagnostic developmental perspective. We provide directions for integrating neuroscience into future process and outcome research. We present examples on how neuroscience can be integrated into researching the effects of contextual counseling interventions. We posit that interpersonal and environmental factors, such as neurotoxic factors (e.g., emotional neglect, stress), positive neurodevelopmental factors (e.g., nurturing and caring, environmental enrichment), and therapeutic interventions influence psychological processes (executive control, behavioral flexibility, reinforcement learning and approach motivation, emotional expression and regulation, self-representation and theory of mind). These psychological processes influence brain networks (attention, motivational, emotional regulation, social cognition), which influence cognitive, social, emotional, identity, and vocational development.
Topics: Biomedical Research; Brain; Counseling; Humans; Mental Disorders; Nerve Net; Neuronal Plasticity; Neuropsychology; Neurosciences; Psychophysiology; Psychotherapy
PubMed: 25285708
DOI: 10.1037/cou0000026