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Soins; La Revue de Reference Infirmiere Oct 2023Considering that it's always a good idea to know where we've come from, in order to better envision where we're going, it's appropriate to look at the evolution of the... (Review)
Review
Considering that it's always a good idea to know where we've come from, in order to better envision where we're going, it's appropriate to look at the evolution of the relationship to care by following the thread of nurses' professional construction and the concomitant transformation of practices. Indeed, if we are to approach the discipline of nursing with serenity, we must first identify the key to its cultural heritage, which defines the way it comes into contact with illness at the patient's bedside.
PubMed: 37778861
DOI: 10.1016/j.soin.2023.08.018 -
Innovative Surgical Sciences Sep 2017Due to the rapidly evolving medical, technological, and technical possibilities, surgical procedures are becoming more and more complex. On the one hand, this offers an... (Review)
Review
Due to the rapidly evolving medical, technological, and technical possibilities, surgical procedures are becoming more and more complex. On the one hand, this offers an increasing number of advantages for patients, such as enhanced patient safety, minimal invasive interventions, and less medical malpractices. On the other hand, it also heightens pressure on surgeons and other clinical staff and has brought about a new policy in hospitals, which must rely on a great number of economic, social, psychological, qualitative, practical, and technological resources. As a result, medical disciplines, such as surgery, are slowly merging with technical disciplines. However, this synergy is not yet fully matured. The current information and communication technology in hospitals cannot manage the clinical and operational sequence adequately. The consequences are breaches in the surgical workflow, extensions in procedure times, and media disruptions. Furthermore, the data accrued in operating rooms (ORs) by surgeons and systems are not sufficiently implemented. A flood of information, "big data", is available from information systems. That might be deployed in the context of Medicine 4.0 to facilitate the surgical treatment. However, it is unused due to infrastructure breaches or communication errors. Surgical process models (SPMs) alleviate these problems. They can be defined as simplified, formal, or semiformal representations of a network of surgery-related activities, reflecting a predefined subset of interest. They can employ different means of generation, languages, and data acquisition strategies. They can represent surgical interventions with high resolution, offering qualifiable and quantifiable information on the course of the intervention on the level of single, minute, surgical work-steps. The basic idea is to gather information concerning the surgical intervention and its activities, such as performance time, surgical instrument used, trajectories, movements, or intervention phases. These data can be gathered by means of workflow recordings. These recordings are abstracted to represent an individual surgical process as a model and are an essential requirement to enable Medicine 4.0 in the OR. Further abstraction can be generated by merging individual process models to form generic SPMs to increase the validity for a larger number of patients. Furthermore, these models can be applied in a wide variety of use-cases. In this regard, the term "modeling" can be used to support either one or more of the following tasks: "to describe", "to understand", "to explain", to optimize", "to learn", "to teach", or "to automate". Possible use-cases are requirements analyses, evaluating surgical assist systems, generating surgeon-specific training-recommendation, creating workflow management systems for ORs, and comparing different surgical strategies. The presented chapter will give an introduction into this challenging topic, presenting different methods to generate SPMs from the workflow in the OR, as well as various use-cases, and state-of-the-art research in this field. Although many examples in the article are given according to SPMs that were computed based on observations, the same approaches can be easily applied to SPMs that were measured automatically and mined from big data.
PubMed: 31579744
DOI: 10.1515/iss-2017-0005 -
NeuroImage Apr 2022What dynamic processes underly functional brain networks? Functional connectivity (FC) and functional connectivity dynamics (FCD) are used to represent the patterns and... (Review)
Review
What dynamic processes underly functional brain networks? Functional connectivity (FC) and functional connectivity dynamics (FCD) are used to represent the patterns and dynamics of functional brain networks. FC(D) is related to the synchrony of brain activity: when brain areas oscillate in a coordinated manner this yields a high correlation between their signal time series. To explain the processes underlying FC(D) we review how synchronized oscillations emerge from coupled neural populations in brain network models (BNMs). From detailed spiking networks to more abstract population models, there is strong support for the idea that the brain operates near critical instabilities that give rise to multistable or metastable dynamics that in turn lead to the intermittently synchronized slow oscillations underlying FC(D). We explore further consequences from these fundamental mechanisms and how they fit with reality. We conclude by highlighting the need for integrative brain models that connect separate mechanisms across levels of description and spatiotemporal scales and link them with cognitive function.
Topics: Cognition; Humans; Models, Neurological; Neural Pathways; Neuroimaging
PubMed: 35101596
DOI: 10.1016/j.neuroimage.2022.118928 -
Personality and Social Psychology... Aug 2023The idea of "purity" transformed moral psychology. Here, we provide the first systematic review of this concept. Although often discussed as one construct, we reveal ~9... (Review)
Review
ACADEMIC ABSTRACT
The idea of "purity" transformed moral psychology. Here, we provide the first systematic review of this concept. Although often discussed as one construct, we reveal ~9 understandings of purity, ranging from respecting God to not eating gross things. This striking heterogeneity arises because purity-unlike other moral constructs-is not understood by what it but what it : obvious interpersonal harm. This poses many problems for moral psychology and explains why purity lacks convergent and divergent validity and why purity is confounded with politics, religion, weirdness, and perceived harm. Because purity is not a coherent construct, it cannot be a distinct basis of moral judgment or specially tied to disgust. Rather than a specific moral domain, purity is best understood as a loose set of themes in moral rhetoric. These themes are scaffolded on cultural understandings of harm-the broad, pluralistic harm outlined by the Theory of Dyadic Morality.
PUBLIC ABSTRACT
People are fascinated by morality-how do people make moral judgments and why do liberals and conservatives seem to frequently disagree? "Purity" is one moral concept often discussed when talking about morality-it has been suggested to capture moral differences across politics and to demonstrate the evolutionary roots of morality, especially the role of disgust in moral judgment. However, despite the many books and articles that mention purity, there is no systematic analysis of purity. Here, we review all existing academic articles focused on purity in morality. We find that purity is an especially messy concept that lacks scientific validity. Because it is so poorly defined and inconsistently measured, it should not be invoked to explain our moral minds or political differences.
Topics: Humans; Morals; Judgment; Disgust; Politics; Religion
PubMed: 36314693
DOI: 10.1177/10888683221124741 -
Philosophical Transactions of the Royal... Aug 2018Numerical knowledge, including number concepts and arithmetic procedures, seems to be a clear-cut case for abstract symbol manipulation. Yet, evidence from perceptual... (Review)
Review
Numerical knowledge, including number concepts and arithmetic procedures, seems to be a clear-cut case for abstract symbol manipulation. Yet, evidence from perceptual and motor behaviour reveals that natural number knowledge and simple arithmetic also remain closely associated with modal experiences. Following a review of behavioural, animal and neuroscience studies of number processing, we propose a revised understanding of psychological number concepts as grounded in physical constraints, embodied in experience and situated through task-specific intentions. The idea that number concepts occupy a range of positions on the continuum between abstract and modal conceptual knowledge also accounts for systematic heuristics and biases in mental arithmetic, thus inviting psycho-logical approaches to the study of the mathematical mind.This article is part of the theme issue 'Varieties of abstract concepts: development, use and representation in the brain'.
Topics: Cognition; Concept Formation; Humans; Knowledge; Mathematical Concepts
PubMed: 29914993
DOI: 10.1098/rstb.2017.0125 -
Frontiers in Robotics and AI 2021A robot swarm is a decentralized system characterized by locality of sensing and communication, self-organization, and redundancy. These characteristics allow robot... (Review)
Review
A robot swarm is a decentralized system characterized by locality of sensing and communication, self-organization, and redundancy. These characteristics allow robot swarms to achieve scalability, flexibility and fault tolerance, properties that are especially valuable in the context of simultaneous localization and mapping (SLAM), specifically in unknown environments that evolve over time. So far, research in SLAM has mainly focused on single- and centralized multi-robot systems-i.e., non-swarm systems. While these systems can produce accurate maps, they are typically not scalable, cannot easily adapt to unexpected changes in the environment, and are prone to failure in hostile environments. Swarm SLAM is a promising approach to SLAM as it could leverage the decentralized nature of a robot swarm and achieve scalable, flexible and fault-tolerant exploration and mapping. However, at the moment of writing, swarm SLAM is a rather novel idea and the field lacks definitions, frameworks, and results. In this work, we present the concept of swarm SLAM and its constraints, both from a technical and an economical point of view. In particular, we highlight the main challenges of swarm SLAM for gathering, sharing, and retrieving information. We also discuss the strengths and weaknesses of this approach against traditional multi-robot SLAM. We believe that swarm SLAM will be particularly useful to produce abstract maps such as topological or simple semantic maps and to operate under time or cost constraints.
PubMed: 33816567
DOI: 10.3389/frobt.2021.618268 -
Abstract concepts and emotion: cross-linguistic evidence and arguments against affective embodiment.Philosophical Transactions of the Royal... Feb 2023How are abstract concepts such as 'freedom' and 'democracy' represented in the mind? One prominent proposal suggests that abstract concepts are grounded in emotion....
How are abstract concepts such as 'freedom' and 'democracy' represented in the mind? One prominent proposal suggests that abstract concepts are grounded in emotion. Supporting this 'affective embodiment' account, abstract concepts are rated to be more strongly positive or more strongly negative than concrete concepts. This paper demonstrates that this finding generalizes across languages by synthesizing rating data from Cantonese, Mandarin Chinese, Croatian, Dutch, French, German, Indonesian, Italian, Polish and Spanish. However, a deeper look at the same data suggests that the idea of emotional grounding only characterizes a small subset of abstract concepts. Moreover, when the concreteness/abstractness dimension is not operationalized using concreteness ratings, it is actually found that concrete concepts are rated as more emotional than abstract ones. Altogether, these results suggest limitations to the idea that emotion is an important factor in the grounding of abstract concepts. This article is part of the theme issue 'Concepts in interaction: social engagement and inner experiences'.
Topics: Humans; Emotions; Linguistics; Language; Concept Formation; Asian People
PubMed: 36571116
DOI: 10.1098/rstb.2021.0368 -
Experimental Physiology Sep 2020What is the topic of this review? We describe a range of techniques in the time, frequency and information domains and their application alone and together for the... (Review)
Review
NEW FINDINGS
What is the topic of this review? We describe a range of techniques in the time, frequency and information domains and their application alone and together for the analysis of blood flux signals acquired using laser Doppler fluximetry. What advances does it highlight? This review highlights the idea of using quantitative measures in different domains and scales to gain a better mechanistic understanding of the complex behaviours in the microcirculation.
ABSTRACT
To date, time- and frequency-domain metrics of signals acquired through laser Doppler fluximetry have been unable to provide consistent and robust measures of the changes that occur in the microcirculation in healthy individuals at rest or in response to a provocation, or in patient cohorts. Recent studies have shown that in many disease states, such as metabolic and cardiovascular disease, there appears to be a reduction in the adaptive capabilities of the microvascular network and a consequent reduction in physiological information content. Here, we introduce non-linear measures for assessing the information content of fluximetry signals and demonstrate how they can yield deeper understanding of network behaviour. In addition, we show how these methods may be adapted to accommodate the multiple time scales modulating blood flow and how they can be used in combination with time- and frequency-domain metrics to discriminate more effectively between the different mechanistic influences on network properties.
Topics: Humans; Laser-Doppler Flowmetry; Microcirculation; Microvessels; Regional Blood Flow; Skin
PubMed: 31875329
DOI: 10.1113/EP087874 -
Cell Communication and Signaling : CCS Feb 2024The phenomenon of phase separation is quite common in cells, and it is involved in multiple processes of life activities. However, the current research on the... (Review)
Review
The phenomenon of phase separation is quite common in cells, and it is involved in multiple processes of life activities. However, the current research on the correlation between protein modifications and phase separation and the interference with the tendency of phase separation has some limitations. Here we focus on several post-translational modifications of proteins, including protein phosphorylation modification at multiple sites, methylation modification, acetylation modification, ubiquitination modification, SUMOylation modification, etc., which regulate the formation of phase separation and the stability of phase separation structure through multivalent interactions. This regulatory role is closely related to the development of neurodegenerative diseases, tumors, viral infections, and other diseases, and also plays essential functions in environmental stress, DNA damage repair, transcriptional regulation, signal transduction, and cell homeostasis of living organisms, which provides an idea to explore the interaction between novel protein post-translational modifications and phase separation. Video Abstract.
Topics: Phase Separation; Protein Processing, Post-Translational; Ubiquitination; Phosphorylation; Proteins; Acetylation
PubMed: 38347544
DOI: 10.1186/s12964-023-01380-1 -
Science & Education 2023Balancing disciplinary knowledge and practical reasoning in problem solving is needed for meaningful learning. In STEM problem solving, science subject matter with...
Balancing disciplinary knowledge and practical reasoning in problem solving is needed for meaningful learning. In STEM problem solving, science subject matter with associated practices often appears distant to learners due to its abstract nature. Consequently, learners experience difficulties making meaningful connections between science and their daily experiences. Applying Dewey's idea of practical and science inquiry and Bereiter's idea of referent-centred and problem-centred knowledge, we examine how integrated STEM problem solving offers opportunities for learners to shuttle between practical and science inquiry and the kinds of knowledge that result from each form of inquiry. We hypothesize that connecting science inquiry with practical inquiry narrows the gap between science and everyday experiences to overcome isolation and fragmentation of science learning. In this study, we examine classroom talk as students engage in problem solving to increase crop yield. Qualitative content analysis of the utterances of six classes of 113 eighth graders and their teachers were conducted for 3 hours of video recordings. Analysis showed an almost equal amount of science and practical inquiry talk. Teachers and students applied their everyday experiences to generate solutions. Science talk was at the basic level of facts and was used to explain reasons for specific design considerations. There was little evidence of higher-level scientific conceptual knowledge being applied. Our observations suggest opportunities for more intentional connections of science to practical problem solving, if we intend to apply higher-order scientific knowledge in problem solving. Deliberate application and reference to scientific knowledge could improve the quality of solutions generated.
PubMed: 35125658
DOI: 10.1007/s11191-021-00310-2