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Journal of Medical Radiation Sciences Jun 2024Liver cancer presents a growing global health concern, necessitating advanced approaches for intervention. This review investigates the use and effectiveness of software... (Review)
Review
INTRODUCTION
Liver cancer presents a growing global health concern, necessitating advanced approaches for intervention. This review investigates the use and effectiveness of software navigation in interventional radiology for liver tumour procedures.
METHODS
In accordance with Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) guidelines, a scoping review was conducted of the literature published between 2013 and 2023 sourcing articles through MEDLINE, Scopus, CINAHL and Embase. Eligible studies focused on liver cancer, utilised cone-beam computed tomography (CBCT), and employed software for intervention. Twenty-one articles were deemed eligible for data extraction and analysis.
RESULTS
Categorised by type, software applications yielded diverse benefits. Feeder detection software significantly enhanced vessel identification, reducing non-target embolisation by up to 43%. Motion correction software demonstrated a 20% enhancement in image quality, effectively mitigating breathing-induced motion artefacts. Liver perfusion software facilitated efficient tumour targeting while simultaneously reducing the occurrence of side effects. Needle guide software enabled precise radiofrequency ablation needle placement. Additionally, these software applications provided detailed anatomical simulations. Overall, software integration resulted in shorter procedures, reduced radiation exposure and decreased contrast media usage.
CONCLUSION
This scoping review highlights the innovative yet relatively underexplored role of software navigation for liver tumour procedures. The integration of software applications not only enhances procedural efficiency but also bolsters operator confidence, and contributes to improved patient outcomes. Despite the current lack of uniformity and standardisation, these software-driven advancements hold significant promise for transforming liver tumour interventions. To realise these benefits, further research is needed to explore the clinical impact and optimal utilisation of software navigation tools in interventional radiology.
Topics: Humans; Liver Neoplasms; Software; Angiography; Cone-Beam Computed Tomography
PubMed: 38305074
DOI: 10.1002/jmrs.760 -
Magnetic Resonance Imaging Jan 2022To accelerate non-rigid motion corrected coronary MR angiography (CMRA) reconstruction by developing a deep learning based non-rigid motion estimation network and...
PURPOSE
To accelerate non-rigid motion corrected coronary MR angiography (CMRA) reconstruction by developing a deep learning based non-rigid motion estimation network and combining this with an efficient implementation of the undersampled motion corrected reconstruction.
METHODS
Undersampled and respiratory motion corrected CMRA with overall short scans of 5 to 10 min have been recently proposed. However, image reconstruction with this approach remains lengthy, since it relies on several non-rigid image registrations to estimate the respiratory motion and on a subsequent iterative optimization to correct for motion during the undersampled reconstruction. Here we introduce a self-supervised diffeomorphic non-rigid respiratory motion estimation network, DiRespME-net, to speed up respiratory motion estimation. We couple this with an efficient GPU-based implementation of the subsequent motion-corrected iterative reconstruction. DiRespME-net is based on a U-Net architecture, and is trained in a self-supervised fashion, with a loss enforcing image similarity and spatial smoothness of the motion fields. Motion predicted by DiRespME-net was used for GPU-based motion-corrected CMRA in 12 test subjects and final images were compared to those produced by state-of-the-art reconstruction. Vessel sharpness and visible length of the right coronary artery (RCA) and the left anterior descending (LAD) coronary artery were used as metrics of image quality for comparison.
RESULTS
No statistically significant difference in image quality was found between images reconstructed with the proposed approach (MC:DiRespME-net) and a motion-corrected reconstruction using cubic B-splines (MC:Nifty-reg). Visible vessel length was not significantly different between methods (RCA: MC:Nifty-reg 5.7 ± 1.7 cm vs MC:DiRespME-net 5.8 ± 1.7 cm, P = 0.32; LAD: MC:Nifty-reg 7.0 ± 2.6 cm vs MC:DiRespME-net 6.9 ± 2.7 cm, P = 0.81). Similarly, no statistically significant difference between methods was observed in terms of vessel sharpness (RCA: MC:Nifty-reg 60.3 ± 7.2% vs MC:DiRespME-net 61.0 ± 6.8%, P = 0.19; LAD: MC:Nifty-reg 57.4 ± 7.9% vs MC:DiRespME-net 58.1 ± 7.5%, P = 0.27). The proposed approach achieved a 50-fold reduction in computation time, resulting in a total reconstruction time of approximately 20 s.
CONCLUSIONS
The proposed self-supervised learning-based motion corrected reconstruction enables fast motion-corrected CMRA image reconstruction, holding promise for integration in clinical routine.
Topics: Coronary Angiography; Coronary Vessels; Heart; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Angiography; Motion; Supervised Machine Learning
PubMed: 34655727
DOI: 10.1016/j.mri.2021.10.004 -
Pixel-level annotated dataset of computed tomography angiography images of acute pulmonary embolism.Scientific Data Aug 2023Pulmonary embolism has a high incidence and mortality, especially if undiagnosed. The examination of choice for diagnosing the disease is computed tomography pulmonary...
Pulmonary embolism has a high incidence and mortality, especially if undiagnosed. The examination of choice for diagnosing the disease is computed tomography pulmonary angiography. As many factors can lead to misinterpretations and diagnostic errors, different groups are utilizing deep learning methods to help improve this process. The diagnostic accuracy of these methods tends to increase by augmenting the training dataset. Deep learning methods can potentially benefit from the use of images acquired with devices from different vendors. To the best of our knowledge, we have developed the first public dataset annotated at the pixel and image levels and the first pixel-level annotated dataset to contain examinations performed with equipment from Toshiba and GE. This dataset includes 40 examinations, half performed with each piece of equipment, representing samples from two medical services. We also included measurements related to the cardiac and circulatory consequences of pulmonary embolism. We encourage the use of this dataset to develop, evaluate and compare the performance of new AI algorithms designed to diagnose PE.
Topics: Humans; Acute Disease; Algorithms; Angiography; Computed Tomography Angiography; Pulmonary Embolism; Tomography, X-Ray Computed
PubMed: 37542053
DOI: 10.1038/s41597-023-02374-x -
Journal of Plastic, Reconstructive &... Oct 2023The use of Indocyanine green angiography (ICG-A) in oncoplastic breast-conserving surgery (OBCS) has not yet been investigated. This prospective trial applied ICG-A in...
INTRODUCTION
The use of Indocyanine green angiography (ICG-A) in oncoplastic breast-conserving surgery (OBCS) has not yet been investigated. This prospective trial applied ICG-A in volume displacement and replacement OBCS to localize perforators and determine tissue supplied by the perforator. Furthermore, to investigate and correlate the intraoperative ICG-A to postoperative surgical site infection, skin necrosis, epidermolysis, and timely onset of adjuvant therapy.
METHODS
ICG-A was performed at three pre-set timepoints during surgery; after lumpectomy, upon dissection of possible perforators, and after wound closure. All patients were followed with clinical evaluations before surgery, 4 weeks, 4-6 months, and 12 months postoperatively.
RESULTS
Eleven patients were included: seven volume displacement and four volume replacement OBCS. ICG-A located the tissue supplied by the perforator and demonstrated sufficient perfusion in all cases. The ICG-A corresponded to the surgeons' clinical assessment. One patient developed a postoperative infection and seroma and was treated conservatively. No patients had postoperative necrosis, loss of reconstruction, or lymphedema of the arm. Edema of the breast occurred in four patients (36.4%). Scar assessments were significantly worse at 4-weeks and 4-6 months. The quality of life improved significantly during follow-up. Adjuvant treatment was administered timely in all cases.
CONCLUSION
ICG-A was feasible for OBCS in assessing intraoperative perfusion. Perfusion was sufficient in all patients and corresponded to the surgeon's clinical evaluation. No patients developed postoperative necrosis. Though edema of the breast occurred in 36.4%, a larger sample size is needed to investigate a possible correlation with ICG-A. Further studies, which includes patients requiring extensive tissue replacement challenging the borders of perfusion, are needed.
Topics: Humans; Female; Prospective Studies; Indocyanine Green; Quality of Life; Angiography; Necrosis; Breast Neoplasms; Fluorescein Angiography
PubMed: 37541044
DOI: 10.1016/j.bjps.2023.07.022 -
JACC. Cardiovascular Imaging Oct 2017
Topics: Angiography, Digital Subtraction; Computed Tomography Angiography; Humans; Lower Extremity; Magnetic Resonance Angiography; Peripheral Arterial Disease
PubMed: 28982569
DOI: 10.1016/j.jcmg.2016.11.012 -
Magnetic Resonance in Medicine Sep 2020Most existing non-contrast-enhanced methods for abdominal MR arteriography rely on a spatially selective inversion (SSI) pulse with a delay to null both static tissue...
PURPOSE
Most existing non-contrast-enhanced methods for abdominal MR arteriography rely on a spatially selective inversion (SSI) pulse with a delay to null both static tissue and venous blood, and are limited to small spatial coverage due to the sensitivity to slow arterial inflow. Velocity-selective inversion (VSI) based approach has been shown to preserve the arterial blood inside the imaging volume at 1.5 T. Recently, velocity-selective saturation (VSS) pulse trains were applied to suppress the static tissue and have been combined with SSI pulses for cerebral MR arteriography at 3 T. The aim of this study is to construct an abdominal MRA protocol with large spatial coverage at 3 T using advanced velocity-selective pulse trains.
METHODS
Multiple velocity-selective MRA protocols with different sequence modules and 3D acquisition methods were evaluated. Sequences using VSS only as well as SSI+VSS and VSI+VSS preparations were then compared among a group of healthy young and middle-aged volunteers. Using MRA without any preparations as reference, relative signal ratios and relative contrast ratios of different vascular segments were quantitatively analyzed.
RESULTS
Both SSI+VSS and VSI+VSS arteriograms achieved high artery-to-tissue and artery-to-vein relative contrast ratios above aortic bifurcation. The SSI+VSS sequence yielded lower signal at the bilateral iliac arteries than VSI+VSS, reflecting the benefit of the VSI preparation for imaging the distal branches.
CONCLUSION
The feasibility of noncontrast 3D MR abdominal arteriography was demonstrated on healthy volunteers using a combination of VSS pulse trains and SSI or VSI pulse.
Topics: Abdomen; Aorta, Abdominal; Arteries; Cerebral Angiography; Contrast Media; Humans; Magnetic Resonance Angiography; Middle Aged
PubMed: 32017173
DOI: 10.1002/mrm.28187 -
Clinical Neuroradiology Sep 2020To apply intracranial vessel wall imaging (VWI) to determine changes in vessel wall characteristics between North American moyamoya patients and controls, as well as...
PURPOSE
To apply intracranial vessel wall imaging (VWI) to determine changes in vessel wall characteristics between North American moyamoya patients and controls, as well as with standard clinical measures of moyamoya disease severity.
METHODS
North American moyamoya patients and controls underwent intracranial 3.0 T VWI. Moyamoya patients also underwent digital subtraction angiography (DSA), from which modified Suzuki scores (mSS) were calculated. Lumen and outer vessel wall diameters of the supraclinoid internal carotid arteries (ICAs) and basilar artery on VWI were measured by two readers from which wall thickness was calculated. Controls and moyamoya patients were compared in logistic regression using disease category (moyamoya or none) as the dependent variable and wall thickness, age, gender, and side as the explanatory variables (significance: two-sided p < 0.05). In moyamoya patients, regression was performed with mSS as the dependent variable and wall thickness, age, gender, and side as the explanatory variables. Analyses were repeated for each lumen diameter and outer vessel wall diameter in place of wall thickness.
RESULTS
Patients with moyamoya (n = 23, gender = 3/20 male/female; age = 43 ± 12 years) and controls (n = 23, gender = 3/20 male/female, age = 43 ± 13 years) were included. Moyamoya patients showed a significantly smaller ICA lumen and outer vessel wall diameter compared to controls (p < 0.05) but no significant change in vessel wall thickness. Similarly, ICA lumen and outer vessel wall diameters decreased with increasing mSS (p < 0.05).
CONCLUSION
Findings suggest decreased ICA lumen and outer vessel wall diameters, but no significant difference in wall thickness, between patients and controls. Lumen and outer vessel wall diameters also decreased with disease severity.
Topics: Adult; Aged; Angiography, Digital Subtraction; Basilar Artery; Carotid Artery, Internal; Case-Control Studies; Cerebral Angiography; Female; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Angiography; Male; Middle Aged; Moyamoya Disease; Severity of Illness Index; United States
PubMed: 31388688
DOI: 10.1007/s00062-019-00819-8 -
Nature Communications Apr 2020In today's clinics, a cell-resolution view of the cornea can be achieved only with a confocal microscope (IVCM) in contact with the eye. Here, we present a common-path...
In today's clinics, a cell-resolution view of the cornea can be achieved only with a confocal microscope (IVCM) in contact with the eye. Here, we present a common-path full-field/spectral-domain OCT microscope (FF/SD OCT), which enables cell-detail imaging of the entire ocular surface in humans (central and peripheral cornea, limbus, sclera, tear film) without contact and in real-time. Real-time performance is achieved through rapid axial eye tracking and simultaneous defocusing correction. Images contain cells and nerves, which can be quantified over a millimetric field-of-view, beyond the capability of IVCM and conventional OCT. In the limbus, palisades of Vogt, vessels, and blood flow can be resolved with high contrast without contrast agent injection. The fast imaging speed of 275 frames/s (0.6 billion pixels/s) allows direct monitoring of blood flow dynamics, enabling creation of high-resolution velocity maps. Tear flow velocity and evaporation time can be measured without fluorescein administration.
Topics: Adult; Angiography; Biomedical Engineering; Blood Flow Velocity; Cornea; Equipment Design; Female; Humans; Limbus Corneae; Male; Microscopy; Optical Imaging; Software; Tomography, Optical Coherence; Young Adult
PubMed: 32313067
DOI: 10.1038/s41467-020-15792-x -
BioMed Research International 2021A 125 cm long catheter makes it possible to perform renal arteriography via radial artery, but its feasibility and safety remain unclear. Our study recruited 1,323...
A 125 cm long catheter makes it possible to perform renal arteriography via radial artery, but its feasibility and safety remain unclear. Our study recruited 1,323 patients grouped by two different vascular accesses to renal arteriography, i.e., femoral artery access and radial artery access. The success rate of angiography was 100% in both groups. Differential analysis showed that the overall complication incidence of radial artery access group was significantly lower (2.5% for radial artery access vs. 4.8% for femoral artery access, = 0.03). From this study, we suggest that using the 125 cm angiographic catheter to perform renal arteriography via radial artery access is feasible and safe.
Topics: Adult; Aged; Aged, 80 and over; Angiography; Catheters; Female; Femoral Artery; Humans; Kidney; Male; Middle Aged; Radial Artery; Renal Artery; Retrospective Studies
PubMed: 33977105
DOI: 10.1155/2021/5564462 -
Current Eye Research May 2023The optic nerve mechanically loads the eye during ocular rotation, thus altering the configuration of the disk and peripapillary tissues. We used optical coherence...
PURPOSE
The optic nerve mechanically loads the eye during ocular rotation, thus altering the configuration of the disk and peripapillary tissues. We used optical coherence tomography (OCT) angiography (OCTA) to investigate mechanical strains and volume changes in disk and peripapillary blood vessels during horizontal duction.
METHODS
Structural OCT and OCTA were performed centered on optic disks; imaging was repeated in central gaze, and in 30° ab- and adduction. By an algorithm employing point-set registration of 3 D features, we developed a novel approach for measuring disk strains, and strains and volumes of the blood vessels associated with horizontal duction. Repeatability was demonstrated in each gaze position.
RESULTS
19 eyes of 10 healthy adults of average age 37 ± 15 (standard deviation, SD) years were imaged. The method was validated by demonstrating numerically consistent vascular volumes and strains for repeated imaging under identical conditions. Compared with central gaze, vascular volume increased by 5.2 ± 4.1% in adduction. Adduction and abduction caused strains of 3.0 ± 1.6% and 2.6 ± 1.8% in the optic disk, whereas blood vessels showed greater strains of 8.1 ± 1.3% and 8.2 ± 1.7%. Decomposition of strain components depending on directionality and regions demonstrated that adduction induces significant net tensile strains, suggesting traction exerted by the optic nerve. The decomposition also showed that nasotemporal compressive strains are larger in temporal hemidisks than nasal hemidisks. The Bruch's membrane opening was significantly compressed horizontally in adduction by 1.1% ( = .009).
CONCLUSION
This novel analysis combining structural OCT and OCTA demonstrates that optic disk compression during adduction is associated with disk and vascular strains much larger than reported for intraocular pressure elevation and pulsatile perfusion, as well as compressing the disk and increasing peripapillary vascular volume. These changes may be relevant to the pathogenesis of optic nerve and retinal vascular disorders.
Topics: Adult; Humans; Young Adult; Middle Aged; Optic Disk; Tomography, Optical Coherence; Optic Nerve Diseases; Optic Nerve; Angiography; Intraocular Pressure; Retinal Vessels; Fluorescein Angiography
PubMed: 36843550
DOI: 10.1080/02713683.2023.2172185