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Lakartidningen Oct 2020
Topics: COVID-19; Coronavirus Infections; Global Health; Goals; Humans; Motivation; Pandemics; Pneumonia, Viral
PubMed: 33051861
DOI: No ID Found -
Sleep Medicine Clinics Sep 2020Telemedicine is about more than simply using audio-visual technology to care for patients, but rather an opportunity to fundamentally improve patient access, quality,... (Review)
Review
Telemedicine is about more than simply using audio-visual technology to care for patients, but rather an opportunity to fundamentally improve patient access, quality, efficiencies, and experience. Regarding sleep medicine, it has the potential to drive sleep medicine's evolution. By enabling care across geographies and facilitating population-based management, sleep medicine is poised to take advantage of telemedicine capabilities. In this introductory chapter, we highlight issues related to sleep telemedicine, while providing a framework in which to approach this transformational journey thoughtfully. We thereby set the stage for the individual chapters in this edition of Sleep Medicine Clinics.
Topics: Humans; Quality of Health Care; Sleep Wake Disorders; Telemedicine
PubMed: 32762967
DOI: 10.1016/j.jsmc.2020.05.005 -
Lakartidningen Mar 2018
Topics: Emigration and Immigration; Global Health; Health Knowledge, Attitudes, Practice; Health Promotion; Health Status Disparities; Humans; Life Style; Socioeconomic Factors
PubMed: 29583162
DOI: No ID Found -
Lakartidningen May 2018
Topics: Biomedical Research; Evidence-Based Medicine; Humans; Meta-Analysis as Topic; Systematic Reviews as Topic
PubMed: 29809269
DOI: No ID Found -
Lakartidningen May 2021Complex diseases represent a number of common disorders such as allergic conditions, cardiovascular, metabolic and chronic inflammatory diseases. These diseases are... (Review)
Review
Complex diseases represent a number of common disorders such as allergic conditions, cardiovascular, metabolic and chronic inflammatory diseases. These diseases are caused by a combination of genetic, environmental and lifestyle factors. This complex etiology creates challenges when it comes to diagnostics, follow-up programs and treatment. Although exact disease mechanisms are yet to be elucidated for most complex diseases, key genetic determinants have been mapped and omics profiling has unraveled involved pathways. Using this wealth of data, precision medicine applications have started to appear also for common, complex diseases. In this article, we review current precision medicine applications from a clinical point of view and outline briefly a roadmap ahead for further clinical implementation of precision medicine in complex diseases.
Topics: Chronic Disease; Humans; Precision Medicine
PubMed: 33977516
DOI: No ID Found -
Emerging Topics in Life Sciences Oct 2021This special issue of Emerging Topics in Life Sciences entitled 'Current Topics in Stem Cells and Regenerative Medicine' brings together expertise from a collaborative...
This special issue of Emerging Topics in Life Sciences entitled 'Current Topics in Stem Cells and Regenerative Medicine' brings together expertise from a collaborative organisation known as the Mercia Stem Cell Alliance (MSCA). The alliance was established initially by Professors Sue Kimber (University of Manchester) and Jon Frampton (University of Birmingham) just over 10 years ago and now has multiple regional centres of excellence across the Midlands and North West of the UK, including Aston University, University of Chester, Keele University, Manchester Metropolitan University, Lancaster University, University of Leicester, University of Liverpool, Liverpool John Moore's University, Loughborough University, University of Nottingham, University of Oxford, University of Sheffield, University of York. Many of these centres have contributed reviews to this issue. The MSCA also partners with industrial and clinical organisations, including the NHS, and is active in bringing stem cells and regenerative medicines to a meaningful translational endpoint (see: http://www.msca.manchester.ac.uk/).
Topics: Humans; Regenerative Medicine; Stem Cells; United Kingdom
PubMed: 34636399
DOI: 10.1042/ETLS20210264 -
Annals of the New York Academy of... Jun 2022Disruptive innovation is a cornerstone of various disciplines, particularly in the business world, where paradigm-altering approaches are often lauded. As a construct,...
Disruptive innovation is a cornerstone of various disciplines, particularly in the business world, where paradigm-altering approaches are often lauded. As a construct, disruptive psychiatry can be considered to embody such an approach by the pursuit of innovations within the field which test boundaries and shake up the status quo. Given the importance of addressing the current mental health pandemic, and the deficit of highly effective pharmacological treatments for various conditions, innovative disruptive thinking is required. Significant promise exists via the provision of potentially more effective innovative therapeutic options, including digital interventions, psychedelic medicines, microbiome-altering treatments, brain stimulation technology, and nanotechnology-based delivery systems. These approaches may be further advanced by individualization of the treatments using computational technology (including quantum computing, machine learning, and artificial intelligence) and genomics.
Topics: Artificial Intelligence; Computing Methodologies; Humans; Machine Learning; Psychiatry; Quantum Theory
PubMed: 35233789
DOI: 10.1111/nyas.14764 -
Canadian Family Physician Medecin de... Apr 2018To raise awareness of narrative-based medicine (NBM) as a valuable approach to the consultation, which, if practised more widely by GPs, would convey considerable... (Review)
Review
OBJECTIVE
To raise awareness of narrative-based medicine (NBM) as a valuable approach to the consultation, which, if practised more widely by GPs, would convey considerable benefits to both patient and doctor.
SOURCES OF INFORMATION
Principally, this article draws on the perspectives of 2 of NBM's key proponents, John Launer and Rita Charon, and which are complemented by the perspectives of several other authors.
MAIN MESSAGE
This article examines NBM in relation to patient-centred care and the particular skills that are required to practise NBM. Narrative-based medicine brings together skills from other fields of practice-skills that are not beyond the capabilities of GPs-conferring benefits on patient and doctor. Narrative-based medicine's skills enhance the patient-centred method and an evidence-based approach.
CONCLUSION
The literature speaks very loudly about the importance of narrative and of understanding the illness experience. What makes NBM stand out is the fact that it is a collaborative and mutually beneficial process, having the power to create a new narrative-a narrative that heals and transforms the patient and the doctor.
Topics: Evidence-Based Medicine; General Practice; Humans; Narration; Patient-Centered Care; Physician-Patient Relations; Referral and Consultation
PubMed: 29650604
DOI: No ID Found -
PLoS Medicine Jun 2020
Topics: Betacoronavirus; Biomedical Research; COVID-19; Coronavirus Infections; Evidence-Based Medicine; Humans; Pandemics; Pneumonia, Viral; Randomized Controlled Trials as Topic; SARS-CoV-2
PubMed: 32603323
DOI: 10.1371/journal.pmed.1003266 -
Forensic Science International Sep 2022Counterfeit, fake, adulterated or falsified drugs and pharmaceuticals, could be branded or generic drugs, excipients and active substances (in drugs and vaccines),... (Review)
Review
Counterfeit, fake, adulterated or falsified drugs and pharmaceuticals, could be branded or generic drugs, excipients and active substances (in drugs and vaccines), medical supplies and devices, etc, intended to pass as the original. Counterfeits are always inferior in terms of quality, safety and efficacy compared to the original pharmaceuticals, and subsequently, they pose an unpredictable risk to public health and lead to loss of confidence in medicines, healthcare providers, and health systems. In the decades before the outbreak of the COVID-19 pandemic, a constant trend of increased trafficking was reported. However, the pandemic created a combination of public health emergency, economic distress, and misinformation-driven panic that made problematic the access and supply of high quality essential medicines and health products, and pushed consumers and vendors even more towards counterfeit pharmaceuticals. This contribution aims to review the trends in counterfeit drugs and pharmaceuticals trafficking, the health impact of their use, as well as, measures and actions implemented to restrict their proliferation, before and during COVID-19 pandemic; the relative recommendations, the expressed perspectives and the existing limitations are thoroughly discussed.
Topics: COVID-19; Counterfeit Drugs; Humans; Pandemics; Public Health
PubMed: 35882074
DOI: 10.1016/j.forsciint.2022.111382