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Journal of Food Science Apr 2022Coriandrum sativum (coriander) is an edible herb in the family Apiaceae. The leaves, fruits, and stems of C. sativum have long been used as culinary spice due to their... (Review)
Review
Coriandrum sativum (coriander) is an edible herb in the family Apiaceae. The leaves, fruits, and stems of C. sativum have long been used as culinary spice due to their favorable odor. Traditional practitioners used this plant for treating different diseases like blepharitis, scabies, aphthous stomatitis, laryngitis, headache, and palpitation. In modern researches, coriander has demonstrated anxiolytic, anticonvulsant, antimigraine, neuroprotective, analgesic, diuretic, hypoglycemic, hypolipidemic, hypotensive, anticancer, and antioxidant activities. Coriander contains a wide range of bioactive phytochemicals among which phenylpropenes, terpenoids, isocoumarins, phytosterols, and fatty acids are the most important. This review provides information about the botanical and ethnobotanical aspects, chemical profile, therapeutic uses in Islamic traditional medicine (ITM), and recent pharmacological studies of coriander effects. The results have shown that coriander and its monoterpenoid compound, linalool, can be considered as potential drug candidates for treating metabolic syndrome and different inflammatory conditions especially neural and CNS diseases.
Topics: Antioxidants; Coriandrum; Monoterpenes; Phytochemicals; Plant Extracts
PubMed: 35279837
DOI: 10.1111/1750-3841.16085 -
Progress in Lipid Research Apr 2023Consumption of diets rich in fruits and vegetables, which provide some fat-soluble vitamins and many phytochemicals, is associated with a lower risk of developing... (Review)
Review
Consumption of diets rich in fruits and vegetables, which provide some fat-soluble vitamins and many phytochemicals, is associated with a lower risk of developing certain degenerative diseases. It is well accepted that not only the parent compounds, but also their derivatives formed upon enzymatic or nonenzymatic transformations, can produce protective biological effects. These derivatives can be formed during food storage, processing, or cooking. They can also be formed in the lumen of the upper digestive tract during digestion, or via metabolism by microbiota in the colon. This review compiles the known metabolites of fat-soluble vitamins and fat-soluble phytochemicals (FSV and FSP) that have been identified in food and in the human digestive tract, or could potentially be present based on the known reactivity of the parent compounds in normal or pathological conditions, or following surgical interventions of the digestive tract or consumption of xenobiotics known to impair lipid absorption. It also covers the very limited data available on the bioavailability (absorption, intestinal mucosa metabolism) and summarizes their effects on health. Notably, despite great interest in identifying bioactive derivatives of FSV and FSP, studying their absorption, and probing their putative health effects, much research remains to be conducted to understand and capitalize on the potential of these molecules to preserve health.
Topics: Humans; Vitamins; Intestinal Absorption; Diet; Phytochemicals
PubMed: 36657621
DOI: 10.1016/j.plipres.2023.101220 -
Molecules (Basel, Switzerland) Aug 2023Millions of people in the world live in food insecurity, so identifying a tuber with characteristics capable of meeting the demand for food and also identifying active... (Review)
Review
Millions of people in the world live in food insecurity, so identifying a tuber with characteristics capable of meeting the demand for food and also identifying active compounds that can be used to minimize harm to human health is of great value. The aim was to carry out a review based on systematic review tools and the main objective was to seek information on botanical, food, pharmacological, and phytochemical aspects of sp. and propose possible applications. This review showed papers that addressed botanical, food, pharmacological, and phytochemical aspects of the Mairá-potato and presented suggestions for using this tuber allied to the information described in the works found in the Google Academic, Scielo, Science Direct, Scopus, PubMed, and Web of Science databases. This review synthesized knowledge about the Mairá-potato that can contribute to the direction of further research on the suggested technological applications, both on the use of this tuber as a polymeric material and its use as biomaterial, encapsulation, bioactive use, and 3D printing, because this work collected information about this non-conventional food plant (PANC) that shows great potential for use in various areas of study.
Topics: Humans; Solanum tuberosum; Food; Biocompatible Materials; Databases, Factual; Magnoliopsida; Phytochemicals
PubMed: 37630321
DOI: 10.3390/molecules28166069 -
Marine Drugs Jul 2018Seaweeds are known to be a good supply of key nutrients including carbohydrates, protein, minerals, polyunsaturated lipids, as well as several other health-promoting... (Review)
Review
Seaweeds are known to be a good supply of key nutrients including carbohydrates, protein, minerals, polyunsaturated lipids, as well as several other health-promoting compounds capable of acting on a wide spectrum of disorders and/or diseases. While these marine macroalgae are deeply rooted in the East Asian culture and dietary habits, their major application in Western countries has been in the phycocolloid industry. This scenario has however been gradually changing, since seaweed consumption is becoming more common worldwide. Among the numerous edible seaweeds, members of the genus have a high nutritional value and are considered good sources of dietary fibers and minerals, especially iodine. Additionally, their wealth of bioactive compounds such as fucoidan, phlorotannins, fucoxanthin and others make them strong candidates for multiple therapeutic applications (e.g., antioxidant, anti-inflammatory, anti-tumor, anti-obesity, anti-coagulant, anti-diabetes and others). This review presents an overview of the nutritional and phytochemical composition of spp., and their claimed biological activities, as well as the beneficial effects associated to their consumption. Furthermore, the use of seaweeds and/or their components as functional ingredients for formulation of novel and enhanced foods is also discussed.
Topics: Fucus; Functional Food; Nutritive Value; Phytochemicals; Plants, Edible; Seaweed
PubMed: 30060505
DOI: 10.3390/md16080249 -
Molecules (Basel, Switzerland) Jun 2020The genera and (Asparagaceae, Nolinoideae) are still poorly resolved phylogenetically. Plants of these genera are commonly distributed in Africa, China, Southeast... (Review)
Review
The genera and (Asparagaceae, Nolinoideae) are still poorly resolved phylogenetically. Plants of these genera are commonly distributed in Africa, China, Southeast Asia, and America. Most of them are cultivated for ornamental and medicinal purposes and are used in various traditional medicines due to the wide range of ethnopharmacological properties. Extensive in vivo and in vitro tests have been carried out to prove the ethnopharmacological claims and other bioactivities. These investigations have been accompanied by the isolation and identification of hundreds of phytochemical constituents. The most characteristic metabolites are steroids, flavonoids, stilbenes, and saponins; many of them exhibit potent analgesic, anti-inflammatory, antimicrobial, antioxidant, antiproliferative, and cytotoxic activities. This review highlights the structures and bioactivities of flavonoids and stilbenoids isolated from and .
Topics: Anti-Inflammatory Agents; Dracaena; Flavonoids; Humans; Phytochemicals; Sansevieria; Stilbenes
PubMed: 32503357
DOI: 10.3390/molecules25112608 -
Molecules (Basel, Switzerland) Jun 2022, a small bush of the Rhamnaceae family, has been widely used in traditional folk medicine, is rich in bioactive molecules, and has many reported pharmacological and... (Review)
Review
, a small bush of the Rhamnaceae family, has been widely used in traditional folk medicine, is rich in bioactive molecules, and has many reported pharmacological and therapeutic properties. : To gather the current knowledge related to the medicinal characteristics of . Specifically, its phytochemical contents and pharmacological activities in the treatment of various diseases such as cancer, diabetes, and cardiovascular diseases, are discussed. : Major scientific literature databases, including PubMed, Scopus, ScienceDirect, SciFinder, Chemical Abstracts, Medicinal and Aromatic Plants Abstracts, Henriette's Herbal Homepage, Dr. Duke's Phytochemical and Ethnobotanical Databases, were searched to retrieve articles related to the review subject. General web searches using Google and Google scholar were also utilized. The search period covered articles published between 1980 and the end of October 2021.The search used the keywords '', AND ('phytochemical content', 'pharmacological properties, or activities, or effects, or roles', 'anti-inflammatory', 'anti-drought', 'anti-thermal', 'anthelmintic', 'antidiabetic',' anticancer', 'anticholinesterase', 'antimicrobial', 'sedative', 'antipyretic', 'analgesic', or 'gastrointestinal'). : This plant is rich in characteristic alkaloids, especially cyclopeptide alkaloids such as nummularine-M. Other phytochemicals, including flavonoids, saponins, glycosides, tannins, and phenolic compounds, are also present. These phytochemicals are responsible for the reported pharmacological properties of , including anti-inflammatory, antioxidant, antimicrobial, anthelmintic, antidiabetic, anticancer, analgesic, and gastrointestinal activities. In addition, has anti-drought and anti-thermal characteristics. : Research into the phytochemical and pharmacological properties of has demonstrated that this plant is a rich source of novel bioactive compounds. So far, has shown a varied pharmacological profile (antioxidant, anticancer, anti-inflammatory, and cardioprotective), warranting further research to uncover the therapeutic potential of the bioactives of this plant. Taken together, may represent a new potential target for the discovery of new drug leads.
Topics: Alkaloids; Antioxidants; Ethnopharmacology; Medicine, Traditional; Phytochemicals; Phytotherapy; Plant Extracts; Ziziphus
PubMed: 35807485
DOI: 10.3390/molecules27134240 -
Nutrients Jan 2018Over the past decades, there has been increasing attention on polyphenol-rich foods including fruits and vegetables on human health. Polyphenols have been shown to... (Review)
Review
Over the past decades, there has been increasing attention on polyphenol-rich foods including fruits and vegetables on human health. Polyphenols have been shown to possess some potential beneficial effects on human health and they are widely found in foods consumed by populations worldwide. () is an important source of different secondary metabolites of interest to humankind. The traditional therapeutic applications of have been reported in Ancient Romans. Numerous bioactive phytochemical constituents have been isolated and identified from different parts (aerial parts, roots and seeds) of which are responsible alone or in combination for its various pharmacological activities. Therefore, this paper is a review of publications on the phytochemical and pharmacological properties of . There is insufficient evidence to suggest that or its extracts are able to improve the biomarkers of cardiovascular disease and diabetes. However, these studies used different parts of plant, methods of preparation and types of solvents, which cause the evaluation of activity of difficult and involve quite heterogeneous data. There is also evidence, although limited, to suggest benefits of in improving human health. Therefore, the relationship between and improved human health outcomes requires further study.
Topics: Biomarkers; Capparis; Humans; Phytochemicals; Plant Extracts; Plant Roots; Plants, Medicinal; Polyphenols; Seeds
PubMed: 29364841
DOI: 10.3390/nu10020116 -
International Journal of Molecular... Sep 2022Naturally occurring bioactives, also known as phytochemicals, have been widely recognized and researched owing to their multiple potentialities [...].
Naturally occurring bioactives, also known as phytochemicals, have been widely recognized and researched owing to their multiple potentialities [...].
Topics: Anti-Inflammatory Agents; Phytochemicals
PubMed: 36232312
DOI: 10.3390/ijms231911016 -
PloS One 2021Medicinal plants represent a great source of antimicrobial and phytochemical constituents which are increasingly used to treat microbial infections and other ailments...
Medicinal plants represent a great source of antimicrobial and phytochemical constituents which are increasingly used to treat microbial infections and other ailments such as tuberculosis, anemia, and trachoma. Despite the use of antibiotics, antimicrobial resistance continues to be a world issue, in as much as nutrition. This study investigated the presence of phytochemicals, proximate compositions, and antimicrobial activity of methanolic extract of Carapa procera bark. The bark of Carapa procera was collected, cleaned and air dried for 72 h. The powder obtained was treated with diethyl ether and soaked in methanol (99%) for 72 h to obtain crude extract. The extract was used to test for the presence of phytochemicals and antimicrobial activities. The raw bark was used for proximate analysis. The result showed presence of steroids, tannins and saponins, but no alkaloids present. The 100 mg/mL extract had the highest inhibition zone on all tested organisms from 24.00 ± 0.94 to 26.67 ± 1.18, and 50 mg/mL showed the least (16.67 ± 1.24) on Candida albicans. Staphylococcus aureus showed the lowest minimum inhibition concentration (MIC) of 3.12 mg/mL, whereas the Gram-negative bacteria exhibited variations in their sensitivity with E. coli having the highest MIC of 25 mg/mL. The extract had high MIC (6.25 mg/mL) on Candida albicans than clotrimazole (50 mg/mL). The proximate compositions of Carapa procera were moisture (6.07 ± 0.07%), ash (12.46 ± 0.46%), crude protein (9.54 ± 0.12%), crude fat (1.42 ± 0.06%) and carbohydrate (70.50 ± 0.35%). The energy value was 1413.17 kj. Thus, Carapa procera possesses both antimicrobial and nutritional potentials worth exploring and domesticating for sustainable management and conservation.
Topics: Anti-Infective Agents; Candida albicans; Meliaceae; Phytochemicals; Plant Bark; Staphylococcus aureus
PubMed: 34941952
DOI: 10.1371/journal.pone.0261755 -
Molecules (Basel, Switzerland) Jun 2021Invasive plant species (IAS), with their numerous negative ecological, health, and economic impacts, represent one of the greatest conservation challenges in the world....
Invasive plant species (IAS), with their numerous negative ecological, health, and economic impacts, represent one of the greatest conservation challenges in the world. Reducing the negative impacts and potentially exploiting the biomass of these plant species can significantly contribute to sustainable management, protect biodiversity, and create a healthy environment. Therefore, the main objective of this study was to evaluate the nutritional potential, phytochemical status, and antioxidant capacity of nine alien invasive plant species: , , , , , , , , and . Multivariate statistical methods such as cluster and PCA were performed to determine possible connections and correlations among selected IAS depending on the phytochemical content. According to the obtained results, was notable with the highest content of vitamin C (38.46 mg/100 g FW); while (1365.92 mg GAE/100 g FW) showed the highest values of total polyphenolic compounds. was characterized by the highest content of total chlorophylls (0.26 mg/g) and antioxidant capacity (2221.97 µmol TE/kg). Therefore, it can be concluded that the selected IAS represent nutrient-rich plant material with significant potential for the recovering of bioactive compounds.
Topics: Biomass; Introduced Species; Phytochemicals; Plant Extracts; Plants
PubMed: 34206657
DOI: 10.3390/molecules26133814