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Innovations in Clinical Neuroscience 2016Surgical treatment is not suitable for laryngopharyngeal reflux that is refractory to proton pump inhibitors. We present a case of proton pump inhibitor-refractory...
Surgical treatment is not suitable for laryngopharyngeal reflux that is refractory to proton pump inhibitors. We present a case of proton pump inhibitor-refractory laryngopharyngeal reflux that was successfully treated with sympathetic nerve entrapment point injection. The patient had previously been diagnosed with laryngopharyngeal reflux and treated with proton pump inhibitors for six months without substantial improvement. After sympathetic nerve entrapment point injection treatment, her reflux symptom index improved from 15 points to 1 point, and this response was maintained for six months. Hyperexcitability of T5 and T6 sympathetic preganglionic fibers appears to be the main cause of laryngopharyngeal reflux. Sympathetic nerve entrapment point injection may represent an alternative to anti-reflux procedures.
PubMed: 28210524
DOI: No ID Found -
Neurologia (Barcelona, Spain) 2016
Topics: Adult; Autonomic Fibers, Postganglionic; Autonomic Fibers, Preganglionic; Diagnosis, Differential; Female; Humans; Magnetic Resonance Imaging; Neuroimaging; Oculomotor Nerve Diseases; Pupil Disorders
PubMed: 24560471
DOI: 10.1016/j.nrl.2013.12.017