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The Lancet. Global Health Oct 2018
Topics: Goals; Humans; Presbyopia; Sustainable Development
PubMed: 30223980
DOI: 10.1016/S2214-109X(18)30376-0 -
Eye and Vision (London, England) 2017Presbyopia affects people from the 4 decade of life and is characterized by accommodative loss that leads to negative effects on vision-targeted health-related quality... (Review)
Review
INTRODUCTION
Presbyopia affects people from the 4 decade of life and is characterized by accommodative loss that leads to negative effects on vision-targeted health-related quality of life. A non-invasive pharmacological treatment providing near-lenses independence would be a truly groundbreaking approach in the treatment of presbyopia. The purpose of this review is to analyze the emerging pharmacological solutions proposed to address presbyopia.
RESULTS
Several ophthalmic eye drops compounds solutions have been described in peer-reviewed papers or presented in ophthalmological tabloids and congresses. Each topical treatment deals with drug combinations aimed to modify one or more factors involved in the accommodative process and have been proposed to be instilled either monocularly or binocularly. It remains unclear how much each drug in the final combined form is involved in the achievement of the outcome and contributes to it.
CONCLUSION
Despite the lack of a completely well understood mechanism, pharmacological control of presbyopia seems to be a possible and very attractive alternative for presbyopic patients. The studies mentioned in this review are to be considered pilot investigations as they involve either a small number of subjects or are single case series. Complete studies are needed to confirm which will be the more effective pharmacological compound for the treatment of presbyopia.
PubMed: 28191476
DOI: 10.1186/s40662-017-0068-8 -
Current Biology : CB Aug 2019Monovision is a common prescription lens correction for presbyopia [1]. Each eye is corrected for a different distance, causing one image to be blurrier than the other....
Monovision is a common prescription lens correction for presbyopia [1]. Each eye is corrected for a different distance, causing one image to be blurrier than the other. Millions of people have monovision corrections, but little is known about how interocular blur differences affect motion perception. Here, we report that blur differences cause a previously unknown motion illusion that makes people dramatically misperceive the distance and three-dimensional direction of moving objects. The effect occurs because the blurry and sharp images are processed at different speeds. For moving objects, the mismatch in processing speed causes a neural disparity, which results in the misperceptions. A variant of a 100-year-old stereo-motion phenomenon called the Pulfrich effect [2], the illusion poses an apparent paradox: blur reduces contrast, and contrast reductions are known to cause neural processing delays [3-6], but our results indicate that blurry images are processed milliseconds more quickly. We resolve the paradox with known properties of the early visual system, show that the misperceptions can be severe enough to impact public safety, and demonstrate that the misperceptions can be eliminated with novel combinations of non-invasive ophthalmic interventions. The fact that substantial perceptual errors are caused by millisecond differences in processing speed highlights the exquisite temporal calibration required for accurate perceptual estimation. The motion illusion-the reverse Pulfrich effect-and the paradigm we use to measure it should help reveal how optical and image properties impact temporal processing, an important but understudied issue in vision and visual neuroscience.
Topics: Adult; Depth Perception; Female; Humans; Illusions; Male; Motion; Motion Perception; Presbyopia; Vision, Monocular; Young Adult
PubMed: 31353183
DOI: 10.1016/j.cub.2019.06.070 -
International Journal of Ophthalmology 2017A systematic review of the recent literature regarding pseudophakic monovision as a reliable methods for presbyopia correction was performed based on the PubMed,... (Review)
Review
A systematic review of the recent literature regarding pseudophakic monovision as a reliable methods for presbyopia correction was performed based on the PubMed, MEDLINE, Nature and the American Academy of Ophthalmology databases in July 2015 and data from 18 descriptive and 12 comparative studies were included in this narrative review. Pseudophakic monosvision seems to be an effective method for presbyopia with high rates of spectacles independence and minimal dysphotopsia side-effects, that should be considered by the modern cataract surgeons.
PubMed: 28730093
DOI: 10.18240/ijo.2017.06.24 -
PloS One 2021The aim of this study was to explore the status of quality of life between the ages 40-59 in relation to presbyopia and dry eye.
PURPOSE
The aim of this study was to explore the status of quality of life between the ages 40-59 in relation to presbyopia and dry eye.
METHODS
Near add power and preferred contact lens power were examined in 219 participants at three clinics. 2000 participants completed a web-based survey on presbyopic symptoms, symptomatic dry eye, sleep quality, and subjective happiness.
RESULTS
Mean preferred corrected visual acuity was less than 20/20 in women (vs men, P<0.01) who were more often prescribed under-corrected contact lenses, whereas men preferred full correction. According to the annual progression rate of near add power in men (0.1468D/year), the estimated difference in presbyopia progression between men and women was 0.75 years in the right eye, and 1.69 years in the left eye, implying men might suffer presbyopia earlier than women due to higher myopic power of daily use contact lenses. The web-based survey revealed that men reported lower subjective happiness than women (P<0.001) and earlier onset of presbyopic symptoms by 1.1-1.7 years (P<0.05). Men received their first reading glasses 0.8 years earlier than women (P = 0.066). Multiple regression analysis demonstrated that awareness of presbyopic symptoms, visual burden, and dry eyes were significantly correlated with poor sleep quality and subjective happiness.
CONCLUSION
Presbyopia and dry eye were significantly associated with sleep quality and subjective happiness in middle-adulthood.
Topics: Adult; Cross-Sectional Studies; Dry Eye Syndromes; Female; Happiness; Health Surveys; Humans; Male; Middle Aged; Presbyopia; Quality of Life; Retrospective Studies; Sex Factors; Sleep
PubMed: 33891599
DOI: 10.1371/journal.pone.0250087 -
The Lancet. Global Health Sep 2018
Topics: Goals; Humans; Presbyopia; Rural Population; Sustainable Development; Tea
PubMed: 30049616
DOI: 10.1016/S2214-109X(18)30355-3 -
Scientific Reports May 2023A new presbyopia-correcting intraocular lens (IOL) combining bifocal and extended-depth-of-focus profiles (Symbiose: Artis Symbiose Plus; Cristalens Industrie, Lannion,...
A new presbyopia-correcting intraocular lens (IOL) combining bifocal and extended-depth-of-focus profiles (Symbiose: Artis Symbiose Plus; Cristalens Industrie, Lannion, France) was introduced. We compared the output with that of a standard monofocal IOL (PL E: Artis PL E). The two four-haptic hydrophobic IOLs were made of the same material from the same company. Cataract patients bilaterally implanted with either PL E or Symbiose between November 2021 and August 2022 were reviewed. The principal measures of the postoperative results were uncorrected distance visual acuity (UDVA); corrected distance VA (CDVA); uncorrected intermediate VA; uncorrected near VA; objective optical quality; and distance-corrected defocus curves. This study included forty-eight patients (96 eyes), with 22 and 26 patients (44 and 52 eyes, respectively) being implanted with PL E and Symbiose, respectively. All patients received the same type of IOL implanted in both eyes. The average age of patients was 70.9 ± 7.1 and 60.0 ± 8.5 years in PL E and Symbiose groups, respectively, with significantly younger patients in Symbiose group (p < 0.001). Both IOLs displayed excellent UDVA and CDVA with no statistical difference (p = 0.081 (monocular UDVA), p = 0.599 (monocular CDVA), p = 0.204 (binocular UDVA), and p = 0.145 (binocular CDVA)). In comparison with PL E group, Symbiose group showed significantly superior postoperative intermediate and near VA (p < 0.001). PL E group showed significantly superior objective optical quality compared with Symbiose group (p < 0.001). Symbiose provides a continuous range of vision that ensures a seamless transition from far to near with no discontinuity. It also delivers a smooth defocus curve with a larger landing area than the PL E. But the objective optical quality was better in PL E.
Topics: Humans; Middle Aged; Aged; Presbyopia; Haptic Technology; Eye, Artificial; Lenses, Intraocular; Eye; Intraocular Lymphoma
PubMed: 37225829
DOI: 10.1038/s41598-023-35377-0 -
The Journal of Physiology Jan 2018
Topics: Humans; Presbyopia; Vision, Monocular; Visual Acuity
PubMed: 29152742
DOI: 10.1113/JP275455 -
Arquivos Brasileiros de Oftalmologia 2023
Topics: Humans; Presbyopia; Accommodation, Ocular
PubMed: 37878949
DOI: 10.5935/0004-2749.2023-0196 -
Life (Basel, Switzerland) Jan 2023Presbyopia can be defined as the refractive state of the eye in which, due to a physiological decrease in the ability to accommodate, it is not possible to sustain... (Review)
Review
Presbyopia can be defined as the refractive state of the eye in which, due to a physiological decrease in the ability to accommodate, it is not possible to sustain vision without fatigue in a prolonged manner, along with difficulty focusing near vision. It is estimated that its prevalence in 2030 will be approximately 2.1 billion people. Corneal inlays are an alternative in the correction of presbyopia. They are implanted beneath a laser-assisted in situ keratomileusis (LASIK) flap or in a pocket in the center of the cornea of the non-dominant eye. The purpose of this review is to provide information about intraoperative and postoperative KAMRA inlay complications in the available scientific literature. A search was conducted on PubMed, Web of Science, and Scopus with the following search strategy: ("KAMRA inlay" OR "KAMRA" OR "corneal inlay pinhole" OR "pinhole effect intracorneal" OR "SAICI" OR "small aperture intracorneal inlay") AND ("complication" OR "explantation" OR "explanted" OR "retired"). The bibliography consulted shows that the insertion of a KAMRA inlay is an effective procedure that improves near vision with a slight decrease in distance vision. However, postoperative complications such as corneal fibrosis, epithelial iron deposits, and stromal haze are described.
PubMed: 36836669
DOI: 10.3390/life13020312