-
Current Cardiology Reports Sep 2022In this review article, a detailed analysis of the current literature is provided, along with a "glimpse" into what the future holds for aspirin in the context of... (Review)
Review
PURPOSE OF REVIEW
In this review article, a detailed analysis of the current literature is provided, along with a "glimpse" into what the future holds for aspirin in the context of primary prevention.
RECENT FINDINGS
The role of aspirin in primary prevention of cardiovascular diseases (CVD) has been extensively evaluated; however, the results provided over the years have been controversial. Identification of individual subgroups who may benefit from aspirin administration at an acceptable risk of bleeding complications is of paramount importance. Additionally, questions emerge at everyday clinical practice regarding the optimal use of aspirin in different phenotypes of patients due to age, sex, obesity status, frailty and diabetes mellitus. Until further data become available, the effective management of the well-established CV risk factors constitutes the milestone in the primary prevention of CVD. Moreover, based on the available evidence, the beneficial addition of aspirin in the modern era of lifestyle and pharmacological interventions for primary CVD prevention remains largely undetermined and further research is needed.
Topics: Aspirin; Cardiovascular Diseases; Diabetes Mellitus; Humans; Primary Prevention; Risk Factors
PubMed: 35857202
DOI: 10.1007/s11886-022-01740-2 -
Cleveland Clinic Journal of Medicine May 2023
Topics: Humans; Aspirin; Platelet Aggregation Inhibitors; Cardiovascular Diseases; Primary Prevention
PubMed: 37127336
DOI: 10.3949/ccjm.90b.05023 -
Cleveland Clinic Journal of Medicine May 2020Recent trials evaluated the impact of aspirin for primary prevention of cardiovascular events in patients at intermediate risk, patients with diabetes, and the elderly,... (Review)
Review
Recent trials evaluated the impact of aspirin for primary prevention of cardiovascular events in patients at intermediate risk, patients with diabetes, and the elderly, and the results have been incorporated into the most recent professional guidelines. For the most part, the role of aspirin in primary prevention remains limited, albeit not adequately tested in those at higher risk.
Topics: Aspirin; Atherosclerosis; Cardiovascular Diseases; Heart Disease Risk Factors; Humans; Platelet Aggregation Inhibitors; Primary Prevention
PubMed: 32357985
DOI: 10.3949/ccjm.87a.19045 -
Journal of the American College of... Dec 2017
Topics: Atherosclerosis; Cholesterol; Humans; Primary Prevention; Risk Factors
PubMed: 29241486
DOI: 10.1016/j.jacc.2017.10.068 -
Complementary Therapies in Medicine May 2021The prevalence of allergic disease has been rapidly increasing in the developed world for over fifty years. The prevention of allergic disease remains one of the most... (Review)
Review
The prevalence of allergic disease has been rapidly increasing in the developed world for over fifty years. The prevention of allergic disease remains one of the most elusive topics in medicine. Integrative medicine emphasizes prevention of disease and utilizes many interventions to help modify long-term outcomes of health. Primary prevention refers to the arrest of manifestations of a disease before they present clinically. Preventing allergy is not simply about preventing sensitization, but also about developing tolerance. This narrative review article will discuss integrative medicine approaches that may help to prevent atopic disease in the pediatric population. It is organized chronologically to aid in counseling patients: 1) prevention during pregnancy and 2) prevention after birth. While research into allergy prevention is in its infancy, Integrative Medicine is well-suited to provide many insights into the prevention and mitigation of atopic disease.
Topics: Child; Female; Food Hypersensitivity; Humans; Integrative Medicine; Pediatrics; Pregnancy; Prevalence; Primary Prevention
PubMed: 33636296
DOI: 10.1016/j.ctim.2021.102695 -
Rheumatology (Oxford, England) May 2018This narrative review discusses the potential of prevention of OA in different stages of the disease. The theoretical background for primary prevention (i.e. prevention... (Review)
Review
This narrative review discusses the potential of prevention of OA in different stages of the disease. The theoretical background for primary prevention (i.e. prevention of occurrence of definite structural or clinical OA in subjects free of the disease) and secondary prevention (i.e. prevention of progression of the disease in subjects with pre-clinical pathological changes to the joint) is provided and evidence for effective strategies is discussed. Since direct evidence for the prevention of OA development and progression is scarce, indirect evidence enhancing our current knowledge on the potential of OA prevention is additionally discussed. Also, implications of preventive strategies for study design and public health are considered. Prevention of OA has great potential, but as deliberated in the current review, there are still large gaps in our current knowledge and the implications of preventive strategies for the development and progression of OA require consideration.
Topics: Disease Progression; Global Health; Humans; Morbidity; Osteoarthritis; Primary Prevention; Public Health
PubMed: 29506178
DOI: 10.1093/rheumatology/key014 -
Journal of the American College of... Jan 2015
Topics: Coronary Disease; Female; Health Behavior; Humans; Primary Prevention
PubMed: 25572510
DOI: 10.1016/j.jacc.2014.10.023 -
Atencion Primaria Nov 2020
Topics: Health Promotion; Humans; Primary Prevention
PubMed: 33388110
DOI: 10.1016/j.aprim.2020.09.006 -
JACC. Cardiovascular Imaging Jan 2020
Topics: Calcinosis; Cause of Death; Coronary Artery Disease; Humans; Primary Prevention
PubMed: 31918909
DOI: 10.1016/j.jcmg.2019.12.007 -
BioMed Research International 2018Cardiovascular diseases result in millions of deaths around the globe annually, most of which are avoidable if identified early. Preventive healthcare has a major role... (Review)
Review
Cardiovascular diseases result in millions of deaths around the globe annually, most of which are avoidable if identified early. Preventive healthcare has a major role in the fight against cardiovascular diseases. Primary, secondary, and tertiary prevention have their own applications along with benefits and drawbacks. This paper aims to elevate the sensitivity of "secondary prevention of cardiovascular diseases." Firstly, it discusses common types of cardiovascular diseases around the globe and their causes. Secondly, it analyzes different risk factors associated with cardiovascular diseases and then discusses incoming technological trends in cardiovascular disease prediction and finally provides an insight into the importance of secondary prevention of cardiovascular diseases and commonly prescribed interventions for high risk patients.
Topics: Cardiovascular Diseases; Early Diagnosis; Humans; Primary Prevention; Risk Factors; Secondary Prevention
PubMed: 29854766
DOI: 10.1155/2018/5767864