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Biomedical Optics Express Mar 2019Frequently, when imaging retinal vasculature with optical coherence tomography angiography (OCTA) in diseased eyes, there are unavoidable obstacles to the propagation of...
Frequently, when imaging retinal vasculature with optical coherence tomography angiography (OCTA) in diseased eyes, there are unavoidable obstacles to the propagation of light such as vitreous floaters or the pupil boundary. These obstacles can block the optical coherence tomography (OCT) beam and impede the visualization of the underlying retinal microcirculation. Detecting these shadow artifacts is especially important in the quantification of metrics that assess retinal disease progression because they might masquerade as regional perfusion loss. In this work, we present an algorithm to identify shadowed areas in OCTA of healthy subjects as well as patients with diabetic retinopathy, uveitis and age-related macular degeneration. The aim is to exclude these areas from analysis so that the overall OCTA parameters are minimally affected by shadow artifacts.
PubMed: 30891364
DOI: 10.1364/BOE.10.001514 -
Clinical Ophthalmology (Auckland, N.Z.) 2014A case of Staphylococcus caprae endophthalmitis in a young patient following pars plana vitrectomy for symptomatic vitreous floaters is reported here. Recent literature...
A case of Staphylococcus caprae endophthalmitis in a young patient following pars plana vitrectomy for symptomatic vitreous floaters is reported here. Recent literature suggests that there is an increasing trend of performing pars plana vitrectomy for symptomatic floaters. Although rare, the potential risk of endophthalmitis should be explicitly discussed with patients considering surgical intervention for vitreous floaters.
PubMed: 25210434
DOI: 10.2147/OPTH.S67855 -
Severe intraocular lens opacification after scleral suturing in a patient with retinitis pigmentosa.Romanian Journal of Ophthalmology 2019To report a case of late intraocular lens (IOL) opacification after scleral suturing in a patient with retinitis pigmentosa. A 36-year-old man presented with visual...
To report a case of late intraocular lens (IOL) opacification after scleral suturing in a patient with retinitis pigmentosa. A 36-year-old man presented with visual impairment increasing gradually over the preceding three months. Seven years earlier, he underwent bilateral phacoemulsification cataract surgery with implantation of a Rayner 620H IOL in the left eye, and a Quatrix P12 IOL in the right eye. Five months prior to admission, scleral suturing of the subluxated IOL in the left eye was performed due to subluxation. Slit lamp examination revealed significant opacities within the IOL and marked vitreous floaters in the left eye. The previous diagnosis of retinitis pigmentosa and rotary nystagmus were confirmed. Subsequently, he underwent 25-gauge vitrectomy with IOL removal in his left eye. Light microscopy of the explanted IOL revealed unevenly distributed microvacuoles. Subsequently, vitrectomy with IOL removal was performed after 3 months in the right eye. The patient had a good recovery of vision, with a visual acuity of 20/200 in both eyes with contact lenses. The presented case demonstrated a significant increase in IOL opacification following scleral suturing. The presumed pathogenesis includes IOL microdeformation with development of IOL matrix cavities and intense inflammatory response related to scleral suturing.
Topics: Adult; Cataract; Device Removal; Humans; Lens Implantation, Intraocular; Lenses, Intraocular; Male; Phacoemulsification; Postoperative Complications; Prosthesis Failure; Reoperation; Retinitis Pigmentosa; Sclera; Suture Techniques; Visual Acuity; Vitrectomy
PubMed: 31915739
DOI: No ID Found -
BMC Ophthalmology Oct 2015Previous studies described cases of Ocriplasmin injections in patients with vitreo-macular traction and reduced central visual acuity. We describe the first case of a...
BACKGROUND
Previous studies described cases of Ocriplasmin injections in patients with vitreo-macular traction and reduced central visual acuity. We describe the first case of a patient with 20/20 visual acuity and vitreo-macular traction treated with Ocriplasmin, and, for the first time in literature, we evaluated the functional changes of the macula in response to pharmacological treatment through multifocal-electroretinogram.
CASE PRESENTATION
We report the case of a female Caucasian patient aged 67 years with vitreo-macular traction in the right eye, treated with Ocriplasmin, at the Eye Clinic of the Second University of Naples. Visual acuity was 20/20 before treatment, associated with metamorphopsia. Two weeks after injection, optical coherence tomography showed the release of vitreo-macular traction and multifocal electroretinogram responses showed a significant increase of retinal density responses in all six rings (pā<ā0.03). Visual acuity remained constant with resolution of symptoms and the appearance of vitreous floaters.
CONCLUSION
Intravitreal injection of Ocriplasmin resulted to be a safe and effective treatment in the case here reported. Our data show that the anatomical recovery with release of vitreo-macular traction was associated with a full functional recovery. In fact, the electrical retinal density response of the macular area improved two weeks after Ocriplasmin injection. Further studies with broader inclusion criteria for Ocriplasmin treatment (e.g. also with visual acuity higher than 20/25) on a larger study sample are needed to confirm our results.
Topics: Aged; Electroretinography; Female; Fibrinolysin; Fibrinolytic Agents; Humans; Intravitreal Injections; Peptide Fragments; Retina; Retinal Diseases; Tissue Adhesions; Tomography, Optical Coherence; Visual Acuity; Vitreous Body
PubMed: 26511080
DOI: 10.1186/s12886-015-0141-9