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International Journal of Molecular... Aug 2023The influence of nanoscale surface topography on protein adsorption is highly important for numerous applications in medicine and technology. Herein, ferritin adsorption...
The influence of nanoscale surface topography on protein adsorption is highly important for numerous applications in medicine and technology. Herein, ferritin adsorption at flat and nanofaceted, single-crystalline AlO surfaces is investigated using atomic force microscopy and X-ray photoelectron spectroscopy. The nanofaceted surfaces are generated by the thermal annealing of AlO wafers at temperatures above 1000 °C, which leads to the formation of faceted saw-tooth-like surface topographies with periodicities of about 160 nm and amplitudes of about 15 nm. Ferritin adsorption at these nanofaceted surfaces is notably suppressed compared to the flat surface at a concentration of 10 mg/mL, which is attributed to lower adsorption affinities of the newly formed facets. Consequently, adsorption is restricted mostly to the pattern grooves, where the proteins can maximize their contact area with the surface. However, this effect depends on the protein concentration, with an inverse trend being observed at 30 mg/mL. Furthermore, different ferritin adsorption behavior is observed at topographically similar nanofacet patterns fabricated at different annealing temperatures and attributed to different step and kink densities. These results demonstrate that while protein adsorption at solid surfaces can be notably affected by nanofacet patterns, fine-tuning protein adsorption in this way requires the precise control of facet properties.
Topics: Ferritins; Adsorption; Medicine; Microscopy, Atomic Force; Photoelectron Spectroscopy
PubMed: 37628990
DOI: 10.3390/ijms241612808 -
Journal of Nanobiotechnology Oct 2023The need for excellent, affordable, rapid, reusable and biocompatible protein purification techniques is justified based on the roles of proteins as key... (Review)
Review
The need for excellent, affordable, rapid, reusable and biocompatible protein purification techniques is justified based on the roles of proteins as key biomacromolecules. Magnetic nanomaterials nowadays have become the subject of discussion in proteomics, drug delivery, and gene sensing due to their various abilities including rapid separation, superparamagnetism, and biocompatibility. These nanomaterials also referred to as magnetic nanoparticles (MNPs) serve as excellent options for traditional protein separation and analytical methods because they have a larger surface area per volume. From ionic metals to carbon-based materials, MNPs are easily functionalized by modifying their surface to precisely recognize and bind proteins. This review excavates state-of-the-art MNPs and their functionalizing agents, as efficient protein separation and purification techniques, including ionic metals, polymers, biomolecules, antibodies, and graphene. The MNPs could be reused and efficaciously manipulated with these nanomaterials leading to highly improved efficiency, adsorption, desorption, and purity rate. We also discuss the binding and selectivity parameters of the MNPs, as well as their future outlook. It is concluded that parameters like charge, size, core-shell, lipophilicity, lipophobicity, and surface energy of the MNPs are crucial when considering protein selectivity, chelation, separation, and purity.
Topics: Magnetite Nanoparticles; Magnetics; Polymers; Adsorption
PubMed: 37794459
DOI: 10.1186/s12951-023-02123-7 -
Journal of Environmental Management Dec 2023Metal-organic frameworks (MOFs) are promising adsorbents for the removal of arsenic (As) from wastewater. The As removal efficiency is influenced by several factors,...
Metal-organic frameworks (MOFs) are promising adsorbents for the removal of arsenic (As) from wastewater. The As removal efficiency is influenced by several factors, such as the textural properties of MOFs, adsorption conditions, and As species. Examining all of the relevant factors through traditional experiments is challenging. To predict the As adsorption capacities of MOFs toward organic, inorganic, and total As and reveal the adsorption mechanisms, four machine learning-based models were developed, with the adsorption conditions, MOF properties, and characteristics of different As species as inputs. The results demonstrated that the extreme gradient boosting (XGBoost) model exhibited the best predictive performance (test R = 0.93-0.96). The validation experiments demonstrated the high accuracy of the inorganic As-based XGBoost model. The feature importance analysis showed that the concentration of As, the surface area of MOFs, and the pH of the solution were the three key factors governing inorganic-As adsorption, while those governing organic-As adsorption were the concentration of As, the pH value of MOFs, and the oxidation state of the metal clusters. The formation of coordination complexes between As and MOFs is possibly the major adsorption mechanism for both inorganic and organic As. However, electrostatic interaction may have a greater effect on organic-As adsorption than on inorganic-As adsorption. Overall, this study provides a new strategy for evaluating As adsorption on MOFs and discovering the underlying decisive factors and adsorption mechanisms, thereby facilitating the investigation of As wastewater treatment.
Topics: Metal-Organic Frameworks; Arsenic; Adsorption; Metals; Machine Learning
PubMed: 37801942
DOI: 10.1016/j.jenvman.2023.119065 -
Huan Jing Ke Xue= Huanjing Kexue Sep 2023CuFeO-modified biochars were prepared through co-precipitation and hydrothermal methods, and the composites had high efficiency removal for tetracycline (TC) from water....
CuFeO-modified biochars were prepared through co-precipitation and hydrothermal methods, and the composites had high efficiency removal for tetracycline (TC) from water. The CuFeO-modified biochar with a 2:1 mass ratio of CuFeO to BC450 (CuFeO/BC450=2:1) demonstrated the best adsorption performance. The kinetic process of TC adsorption by CuFeO/BC450=2:1 was well fitted with the intraparticle diffusion model, suggesting that the adsorption process was controlled by film and pore diffusion. Under the condition of neutral pH and 298 K, the maximum adsorption capacity of the Langmuir model of CuFeO/BC450=2:1 was 82.8 mg·g, which was much greater than that of BC450 (13.7 mg·g) and CuFeO(14.8 mg·g). The thermodynamic data suggested that TC sorption onto CuFeO/BC450=2:1 was a spontaneous and endothermic process. The removal of TC by CuFeO/BC450=2:1 increased first and then decreased with increasing pH, and the maximum adsorption occurred under the neutral condition. The strong adsorption of TC by CuFeO/BC450=2:1 could be attributed to better porosity, larger specific surface area, and more active sites (e.g., functional groups and charged surfaces). This work provided an efficient magnetic adsorbent for removing antibiotics.
Topics: Adsorption; Tetracycline; Anti-Bacterial Agents; Thermodynamics
PubMed: 37699840
DOI: 10.13227/j.hjkx.202209299 -
Bioresource Technology Nov 2023Crop residues are affordable lignocellulosic waste in the world, and a large portion of the waste has been burned, releasing toxic pollutants into the environment. Since... (Review)
Review
Crop residues are affordable lignocellulosic waste in the world, and a large portion of the waste has been burned, releasing toxic pollutants into the environment. Since the crop residue is a carbon and ingredient rich material, it can be strategically used as a sorptive material for (in)organic pollutants in the wastewater after thermo-chemical valorization (i.e., biochar production). In this review, applications of crop residue biochars to adsorption of non-degradable synthetic dyes, antibiotics, herbicides, and inorganic heavy metals in wastewater were discussed. Properties (porosity, functional groups, heteroatom, and metal(oxide)s, etc.) and adsorption capacity relationships were comprehensively reviewed. The current challenges of crop residue biochars and guidelines for development of efficient adsorbents were also provided. In the last part, the future research directions for practical applications of the crop residue biochars in wastewater treatment plants have been suggested.
Topics: Wastewater; Adsorption; Anti-Bacterial Agents; Environmental Pollutants
PubMed: 37591466
DOI: 10.1016/j.biortech.2023.129658 -
Revista de Investigacion Clinica;... Dec 2023Membranes and sorbents play a crucial role in extracorporeal blood purification therapies, which aim to remove harmful molecules and toxins from the blood. Over the... (Review)
Review
Membranes and sorbents play a crucial role in extracorporeal blood purification therapies, which aim to remove harmful molecules and toxins from the blood. Over the years, advancements in hemodialysis (HD) membranes and sorbents have significantly enhanced their safety and effectiveness. This review article will summarize the latest breakthroughs in the development and clinical application of HD membranes and sorbents. We will commence with a concise examination of the mechanisms involved in solute transport across membranes and sorbents. Subsequently, we will explore the evolutionary path of HD membranes, from early cellophane membranes to high-flux membranes, including the development of high-cutoff membranes and the emergence of medium- cutoff membranes. We will discuss each type of HD membrane's advantages and limitations, highlighting the most promising advancements in novel biomaterials and biocompatibility, technologies, research in membrane performance, and their clinical applications. Furthermore, we will delve into the evolution and progress of sorbent technology, tracing its historical development, outlining its key characteristics, examining the mechanism involved in the adsorption process, and exploring its clinical application. This review aims to underscore the growth and future landscape of HD membranes and sorbents in extracorporeal blood purification techniques.
Topics: Humans; Renal Dialysis; Adsorption
PubMed: 37913784
DOI: 10.24875/RIC.23000223 -
Toxins Jan 2024With the rapid advancement of nanotechnology and its widespread applications, increasing amounts of manufactured and natural nanoparticles (NPs) have been tested for... (Review)
Review
With the rapid advancement of nanotechnology and its widespread applications, increasing amounts of manufactured and natural nanoparticles (NPs) have been tested for their potential utilization in treating harmful cyanobacterial blooms (HCBs). NPs can be used as a photocatalyst, algaecide, adsorbent, flocculant, or coagulant. The primary mechanisms explored for NPs to mitigate HCBs include photocatalysis, metal ion-induced cytotoxicity, physical disruption of the cell membrane, light-shielding, flocculation/coagulation/sedimentation of cyanobacterial cells, and the removal of phosphorus (P) and cyanotoxins from bloom water by adsorption. As an emerging and promising chemical/physical approach for HCB mitigation, versatile NP-based technologies offer great advantages, such as being environmentally benign, cost-effective, highly efficient, recyclable, and adaptable. The challenges we face include cost reduction, scalability, and impacts on non-target species co-inhabiting in the same environment. Further efforts are required to scale up to real-world operations through developing more efficient, recoverable, reusable, and deployable NP-based lattices or materials that are adaptable to bloom events in different water bodies of different sizes, such as reservoirs, lakes, rivers, and marine environments.
Topics: Cyanobacteria; Adsorption; Biological Assay; Nanoparticles; Water
PubMed: 38251256
DOI: 10.3390/toxins16010041 -
Waste Management (New York, N.Y.) Aug 2023The treatment of combined antibiotics and heavy metals pollution is a critical challenge. Herein, iron and nitrogen co-doped biochar (Fe/N-BC) was synthesized using rape...
The treatment of combined antibiotics and heavy metals pollution is a critical challenge. Herein, iron and nitrogen co-doped biochar (Fe/N-BC) was synthesized using rape straw as precursor, and applied for the adsorption of ciprofloxacin (CIP) and Cu in single and binary systems. The q for CIP and Cu were 46.45 mg g and 30.77 mg g, respectively. Adsorption decreased in a binary matrix, indicating that there was a competitive effect between CIP and Cu, which might be due to CIP and Cu sharing similar active adsorption sites on Fe/N-BC. Interestingly, CIP and Cu co-adsorption was a pH-dependent process. Fe/N-BC has potential to highly selectively separate CIP/Cu from mixed solutions through adjusting pH values. Furthermore, adsorption mechanisms were systematically investigated in this research. This research could help to provide a deeper understanding of the synchronously removing specific antibiotics and heavy metals by biochar adsorbents.
Topics: Ciprofloxacin; Adsorption; Anti-Bacterial Agents; Charcoal; Metals, Heavy; Water Pollutants, Chemical
PubMed: 37348381
DOI: 10.1016/j.wasman.2023.06.014 -
Environmental Science and Pollution... Aug 2023The work proposes the application of a nanocomposite formed by graphene oxide and magnetite to remove chloroquine, propranolol, and metformin from water. Tests related...
The work proposes the application of a nanocomposite formed by graphene oxide and magnetite to remove chloroquine, propranolol, and metformin from water. Tests related to adsorption kinetics, equilibrium isotherms and adsorbent reuse were studied, and optimization parameters related to the initial pH of the solution and the adsorbent dosage were defined. For all pharmaceuticals, adsorption tests indicated that removal efficiency was independent of initial pH at adsorbent dosages of 0.4 g L for chloroquine, 1.2 g L for propranolol, and 1.6 g L for metformin. Adsorption equilibrium was reached within the first few minutes, and the pseudo-second-order model represented the experimental data well. While the equilibrium data fit the Sips isotherm model at 298 K, the predicted maximum adsorption capacities for chloroquine, propranolol, and metformin were 44.01, 16.82, and 12.23 mg g, respectively. The magnetic nanocomposite can be reused for three consecutive cycles of adsorption-desorption for all pharmaceuticals, being a promising alternative for the removal of different classes of pharmaceuticals in water.
Topics: Adsorption; Propranolol; Chloroquine; Metformin; Water; Graphite; Magnetic Phenomena; Nanocomposites; Pharmaceutical Preparations; Kinetics; Water Pollutants, Chemical; Hydrogen-Ion Concentration
PubMed: 37382818
DOI: 10.1007/s11356-023-28242-0 -
Chemosphere Oct 2023Aminoglycoside antibiotics (AGs) in environmental water are emerging pollutants that must be removed to protect human health and the ecosystem. However, removing AGs...
Aminoglycoside antibiotics (AGs) in environmental water are emerging pollutants that must be removed to protect human health and the ecosystem. However, removing AGs from environmental water remains a technical challenge due to high polarity, stronger hydrophilicity and unique characteristics of polycation. Herein, a thermal-crosslinked polyvinyl alcohol electrospun nanofiber membrane (T-PVA NFsM) is synthesized and firstly leveraged as the adsorptive removal of AGs from environmental water. The thermal crosslinking strategy is demonstrated to enhance both the water resistance and hydrophilicity of T-PVA NFsM, thereby effectively interacting with AGs with high stability. Experimental characterizations and analog calculations indicate that T-PVA NFsM utilizes multiple adsorption mechanisms, including electrostatic and hydrogen bonding interactions with AGs. As a result, the material achieves 91.09%-100% adsorption efficiencies and a maximum adsorption capacity of 110.35 mg g in less than 30 min. Furthermore, the adsorption kinetics follow the pseudo-second-order model. After eight consecutive adsorption-desorption cycles, T-PVA NFsM with a simplified recycling process maintains a sustainable adsorption capability. Compared with other forms of adsorption materials, T-PVA NFsM has significant advantages such as less consumption of adsorbent, high adsorption efficiency and fast removal speed. Therefore, T-PVA NFsM-based adsorptive removal holds promise for eliminating AGs from environmental water.
Topics: Humans; Adsorption; Water; Ecosystem; Anti-Bacterial Agents; Water Pollutants, Chemical; Aminoglycosides; Kinetics; Hydrogen-Ion Concentration; Polyvinyl Alcohol
PubMed: 37422219
DOI: 10.1016/j.chemosphere.2023.139379