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Cold Spring Harbor Protocols Sep 2023Here, we highlight three different assays that are used to study aggression. The advantages and disadvantages of each assay are discussed, as examining different...
Here, we highlight three different assays that are used to study aggression. The advantages and disadvantages of each assay are discussed, as examining different aspects of aggressive behavior presents distinct challenges to researchers. This is because aggression is not a singular behavioral unit. Rather, aggression is the result of interactions between individuals; and, as such, the initiation and frequency of these interactions are impacted by the assay parameters including the method of loading the flies into the observation chamber, the size of the chamber, and the animals' previous social experience. Thus, determining which assay to use depends on the overall question that is the subject of investigation.
Topics: Animals; Drosophila; Aggression; Drosophila melanogaster; Behavior, Animal
PubMed: 37019607
DOI: 10.1101/pdb.prot108144 -
Psychiatria Danubina 2023To compare adolescents clinically diagnosed with Internet Gaming Disorder (IGD) and problematic internet use (PIU) in terms of cyberbullying, aggression, and loneliness.
AIMS
To compare adolescents clinically diagnosed with Internet Gaming Disorder (IGD) and problematic internet use (PIU) in terms of cyberbullying, aggression, and loneliness.
METHODS
Male adolescent patients (N=124, 14.3±1.7 years) with Internet Addiction Scale (IAS) scores ≥50 were clinically interviewed for IGD in utilizing DSM-5 criteria. Patients without full IGD criteria were included as PIU comparisons. Clinical variables were assessed using the second version of the Revised Cyber Bullying Inventory, short-form of the UCLA Loneliness Scale, Buss Perry Aggression Questionnaire, Child Depression Inventory, and Screen for Child Anxiety Related Emotional Disorders.
RESULTS
Compared to individuals with PIU, those with IGD were significantly more likely to have attention-deficit hyperactivity disorder, higher social phobia scores, higher cyberbullying scores, higher loneliness scores, been a cyberbully, and been a cyberbully victim.
CONCLUSION
Male adolescents with IGD have higher rates of psychiatric comorbidity, perceived loneliness, cyberbullying, and being a victim of cyberbullying than those with PIU. Future studies could evaluate these predictors of transition from PIU to IGD in large cohort samples.
Topics: Child; Adolescent; Humans; Male; Cyberbullying; Internet Addiction Disorder; Loneliness; Internet Use; Behavior, Addictive; Comorbidity; Aggression; Internet
PubMed: 37917844
DOI: 10.24869/psyd.2023.395 -
European Review For Medical and... Nov 2023This cross-sectional study aimed to examine the relationship between premenstrual syndrome (PMS) and aggression during adolescence with body mass index (BMI), which is a...
OBJECTIVE
This cross-sectional study aimed to examine the relationship between premenstrual syndrome (PMS) and aggression during adolescence with body mass index (BMI), which is a topic not yet investigated in the literature.
PATIENTS AND METHODS
This cross-sectional study was conducted with 1,450 adolescents aged 12-18 years, who applied to the Pediatric Adolescent Outpatient Clinic and voluntarily agreed to participate in the study. Anthropometric measurements of the adolescents were taken and the Premenstrual Syndrome Scale and Buss-Perry Aggression Questionnaire were administered to the adolescents. It was discovered that all the adolescents participating in the study had PMS.
RESULTS
It was determined that as the levels of PMS were elevated, physical aggression, hostility, anger and verbal aggression gradually increased. Additionally, this increase was statistically significant (p<0.001). It was further discovered that there were statistically significant differences between the BMI classifications of the adolescents and PMS, physical aggression, hostility, anger and verbal aggression statuses (p<0.001). Accordingly, it was determined that as the BMI values of the adolescents increased, PMS and aggressive attitude levels increased.
CONCLUSIONS
This study is the first in the literature to examine the relationship between PMS and aggression, and BMI in adolescents. Within this framework, it was determined that PMS frequency and aggression levels were high in overweight/obese adolescents. Accordingly, it is predicted that both PMS and aggression levels can decrease with healthy body weight in adolescents.
Topics: Female; Child; Adolescent; Humans; Body Mass Index; Cross-Sectional Studies; Aggression; Anger; Premenstrual Syndrome; Surveys and Questionnaires
PubMed: 38039034
DOI: 10.26355/eurrev_202311_34472 -
Nurse Education Today Sep 2023To identify the prevalence of student-directed violence on clinical placement and description of their related experience during clinical placements. (Meta-Analysis)
Meta-Analysis Review
OBJECTIVES
To identify the prevalence of student-directed violence on clinical placement and description of their related experience during clinical placements.
DESIGN
Mixed methods systematic review and meta-analysis conducted following Joanna Briggs Institute guidelines and reported according to Preferred Reporting of Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
DATA SOURCES
CINAHL, Embase, Medline, Proquest, PsycINFO and Google Scholar.
REVIEW METHODS
Included studies were peer reviewed, published primary studies where pre-registration nursing students were surveyed about their experiences of physical, verbal, or sexual aggression, bullying or racism during clinical placement. Studies were quality assessed but not excluded based on the result. A convergent segregated approach to synthesis and integration was undertaken. Prevalence data were extracted and pooled using both random and quality effects models; separate analyses were conducted by violence type, source, and region. Qualitative data were thematically analysed.
RESULTS
14,894 student nurses from 42 studies were included across the meta-analyses. There was substantial heterogeneity in the included data. Pooled prevalence rates ranged from racism 12.2 % to bullying 58.2 %. Bullying (38.8 %) and physical aggression (10.2 %) were most perpetrated by nurses whereas sexual aggression was perpetrated mostly by patients (64.2 %) and physicians (18.6 %). Qualitative findings identified students' descriptions of reasons for, effects of, strategies for dealing with and higher education establishments' responsibilities with regards to workplace violence.
CONCLUSIONS
Student nurses commonly experience violence during their clinical placements. Given the potential debilitating physical and psychological sequelae of all forms of violence then this study further emphasises the need to use multiple strategies to prevent violence and to better equip student nurses to manage potentially violent incidents, their responses to violence, and to whistle blow or report when they are subject to violence.
Topics: Humans; Workplace Violence; Students, Nursing; Aggression; Bullying; Nurses; Workplace
PubMed: 37300926
DOI: 10.1016/j.nedt.2023.105845 -
Substance Use & Addiction Journal Jul 2024Drug and alcohol use before the age of 14 is associated with adverse outcomes over the life course. While previous studies have identified numerous sociodemographic...
BACKGROUND
Drug and alcohol use before the age of 14 is associated with adverse outcomes over the life course. While previous studies have identified numerous sociodemographic characteristics associated with youth substance use initiation, few have examined the relationship between behavioral characteristics, such as childhood aggression, and substance use initiation in adolescence.
METHODS
This longitudinal study consisted of 2985 children from the Future of Families and Child Wellbeing Study. Aggression was measured using primary caregiver report when the children were about the age of 9 and cigarette, alcohol, and marijuana use was measured using the child report when the children were age 9 and age 15. Separate multivariable Poisson regression models were fitted for each substance use initiation outcome.
RESULTS
Childhood aggression was positively associated with the initiation of cigarette and marijuana use in adolescence (aRR = 2.3 [95% CI = 1.5,3.4] and aRR = 1.3 [95% CI = 1.1,1.6], respectively). Childhood aggression was not associated with adolescent alcohol use initiation (aRR = 1.2 [95% CI = 0.9,1.5]).
CONCLUSIONS
The presence of aggressive behavior in childhood was associated with the initiation of cigarette and marijuana use in adolescence. These results may be used to identify children at higher risk of cigarette and marijuana use, who may benefit from additional monitoring for substance use initiation.
Topics: Humans; Adolescent; Female; Male; Aggression; Child; Longitudinal Studies; Adolescent Behavior; Child Behavior; Underage Drinking; Cigarette Smoking; Substance-Related Disorders; Alcohol Drinking; Marijuana Use
PubMed: 38254275
DOI: 10.1177/29767342231226084 -
Aggressive Behavior Jan 2024The study examined the relationship between mistrust and aggression from childhood to adulthood. The participants resided in Portugal and were tested during middle...
The study examined the relationship between mistrust and aggression from childhood to adulthood. The participants resided in Portugal and were tested during middle childhood (Mage = 7.5, SD = 0.81 years, n = 445, 240 male), preadolescence (Mage = 11.92, SD = 0.96 years, n = 431, 200 male), mid-adolescence (Mage = 14.70, SD = 0.91 years, n = 326, 201 male), late adolescence (Mage = 18.14, SD = 1.19 years, n = 410, 216 male), and adulthood (Mage = 26.56, SD = 1.13, years, n = 417, 197 male). Mothers reported the participants' mistrust during childhood and preadolescence on items from the Child Behavior Checklist. Aggression was assessed by standardized self-report measures at each age period. It was found that mistrust was associated with aggression during preadolescence and predicted changes in aggression to mid-adolescence and adulthood. The findings supported the conclusion that mistrust during preadolescence predisposes individuals to show aggression later in the life course.
Topics: Female; Adolescent; Humans; Child; Male; Young Adult; Aggression; Longitudinal Studies; Mothers; Self Report; Portugal
PubMed: 37936509
DOI: 10.1002/ab.22119 -
PloS One 2023Mechanical signals play a vital role in cell biology and is a vast area of research. Thus, there is motivation to understand cell deformation and mechanobiological...
Mechanical signals play a vital role in cell biology and is a vast area of research. Thus, there is motivation to understand cell deformation and mechanobiological responses. However, the ability to controllably deform cells in the ultrasonic regime and test their response is a noted challenge throughout the literature. Quantifying and eliciting an appropriate stimulus has proven to be difficult, resulting in methods that are either too aggressive or oversimplified. Furthermore, the ability to gain a real-time insight into cell deformation and link this with the biological response is yet to be achieved. One application of this understanding is in ultrasonic surgical cutting, which is a promising alternative to traditional methods, but with little understanding of its effect on cells. Here we present the image based ultrasonic cell shaking test, a novel method that enables controllable loading of cells and quantification of their response to ultrasonic vibrations. Practically, this involves seeding cells on a substrate that resonates at ultrasonic frequencies and transfers the deformation to the cells. This is then incorporated into microscopic imaging techniques to obtain high-speed images of ultrasonic cell deformation that can be analysed using digital image correlation techniques. Cells can then be extracted after excitation to undergo analysis to understand the biological response to the deformation. This method could aid in understanding the effects of ultrasonic stimulation on cells and how activated mechanobiological pathways result in physical and biochemical responses.
Topics: Ultrasonics; Ultrasonic Waves; Aggression; Biophysics; Motivation
PubMed: 37713387
DOI: 10.1371/journal.pone.0285906 -
Psychodynamic Psychiatry Mar 2024Access to one's healthy aggression is critical for both patient and therapist. On the patient's end, the ability to access and modulate aggression is fundamental to the...
Access to one's healthy aggression is critical for both patient and therapist. On the patient's end, the ability to access and modulate aggression is fundamental to the establishment of healthy self-esteem and the capacity to sustain relationships and pursue life goals. On the therapist's end, access to aggression allows for the setting of a secure therapeutic frame and the subsequent conduct of the deep work of therapy. Conversely, lack of access to aggression creates burdensome and problematic situations that may subvert the treatment. Beginning therapists have a particular susceptibility to minimize their own aggression given certain factors in their choice of profession. Supervisors' modeling of the experience of aggression, as well as the provision of a safe atmosphere in which new clinicians become comfortably aware of their own and their patients' aggression, will help fortify beginning therapists' capacity to harness their aggression in the service of the work.
Topics: Humans; Psychotherapy, Psychodynamic; Aggression; Professional-Patient Relations; Psychotherapy
PubMed: 38426753
DOI: 10.1521/pdps.2024.52.1.96 -
Translational Psychiatry Jun 2024Excessive and persistent aggressiveness is the most common behavioral problem that leads to psychiatric referrals among children. While half of the variance in childhood...
Excessive and persistent aggressiveness is the most common behavioral problem that leads to psychiatric referrals among children. While half of the variance in childhood aggression is attributed to genetic factors, the biological mechanism and the interplay between genes and environment that results in aggression remains elusive. The purpose of this systematic review is to provide an overview of studies examining the genetics of childhood aggression irrespective of psychiatric diagnosis. PubMed, PsycINFO, and MEDLINE databases were searched using predefined search terms for aggression, genes and the specific age group. From the 652 initially yielded studies, eighty-seven studies were systematically extracted for full-text review and for further quality assessment analyses. Findings show that (i) investigation of candidate genes, especially of MAOA (17 studies), DRD4 (13 studies), and COMT (12 studies) continue to dominate the field, although studies using other research designs and methods including genome-wide association and epigenetic studies are increasing, (ii) the published articles tend to be moderate in sizes, with variable methods of assessing aggressive behavior and inconsistent categorizations of tandem repeat variants, resulting in inconclusive findings of genetic main effects, gene-gene, and gene-environment interactions, (iii) the majority of studies are conducted on European, male-only or male-female mixed, participants. To our knowledge, this is the first study to systematically review the effects of genes on youth aggression. To understand the genetic underpinnings of childhood aggression, more research is required with larger, more diverse sample sets, consistent and reliable assessments and standardized definition of the aggression phenotypes. The search for the biological mechanisms underlying child aggression will also benefit from more varied research methods, including epigenetic studies, transcriptomic studies, gene system and genome-wide studies, longitudinal studies that track changes in risk/ameliorating factors and aggression-related outcomes, and studies examining causal mechanisms.
Topics: Child; Female; Humans; Male; Aggression; Catechol O-Methyltransferase; Gene-Environment Interaction; Genome-Wide Association Study; Monoamine Oxidase; Receptors, Dopamine D4
PubMed: 38862490
DOI: 10.1038/s41398-024-02870-7 -
Aggressive Behavior Sep 2023One of the oldest scientific theories of human aggression is the frustration-aggression hypothesis, advanced in 1939. Although this theory has received considerable...
One of the oldest scientific theories of human aggression is the frustration-aggression hypothesis, advanced in 1939. Although this theory has received considerable empirical support and is alive and well today, its underlying mechanisms have not been adequately explored. In this article, we examine major findings and concepts from extant psychological research on hostile aggression and offer an integrative conception: aggression is a primordial means for establishing one's sense of significance and mattering, thus addressing a fundamental social-psychological need. Our functional portrayal of aggression as a means to significance yields four testable hypotheses: (1) frustration will elicit hostile aggression proportionately to the extent that the frustrated goal serves the individual's need for significance, (2) the impulse to aggress in response to significance loss will be enhanced in conditions that limit the individual's ability to reflect and engage in extensive information processing (that may bring up alternative, socially condoned means to significance), (3) significance-reducing frustration will elicit hostile aggression unless the impulse to aggress is substituted by a nonaggressive means of significance restoration, (4) apart from significance loss, an opportunity for significance gain can increase the impulse to aggress. These hypotheses are supported by extant data as well as novel research findings in real-world contexts. They have important implications for understanding human aggression and the conditions under which it is likely to be manifested and reduced.
Topics: Humans; Frustration; Aggression; Hostility; Motivation
PubMed: 37282763
DOI: 10.1002/ab.22092