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Environmental Science & Technology Jul 2023Volatile organic compounds (VOCs) harm the environment and human health and have been of wide concern and purified efficiently by catalytic oxidation. Spinel oxides,... (Review)
Review
Volatile organic compounds (VOCs) harm the environment and human health and have been of wide concern and purified efficiently by catalytic oxidation. Spinel oxides, mainly composed of transition metal elements with low price and extensive sources, have been widely investigated as efficient and stable catalysts for VOCs oxidation due to their adjustable element composition, flexible structure, and high thermal/chemical stability. However, it is necessary to dissect the design of the spinel in a targeted way to satisfy the removal of different types of VOCs. This article systematically summarizes the recent advances regarding the application of spinel oxides for VOCs catalytic oxidation. Specifically, the design strategies of spinel oxides were first introduced to clarify their effect on the structure and properties of the catalyst. Then the reaction mechanism and degradation pathway of different kinds of VOCs on the spinel oxides were in detail summarized, and the characteristic requirements of the spinel oxides for various VOCs purification were analyzed. Furthermore, the practice applications were also discussed. Finally, the prospects were proposed to guide the rational design of spinel-based catalysts for VOCs purification and intensify the understanding of reaction mechanisms.
Topics: Humans; Oxides; Volatile Organic Compounds; Oxidation-Reduction; Aluminum Oxide; Catalysis
PubMed: 37313598
DOI: 10.1021/acs.est.2c09861 -
Drug Delivery Dec 2023Recently, various novel drug delivery systems have been developed to overcome ocular barriers in order to improve drug efficacy. We have previously reported that...
Physicochemical properties and micro-interaction between micro-nanoparticles and anterior corneal multilayer biological interface film for improving drug delivery efficacy: the transformation of tear film turnover mode.
Recently, various novel drug delivery systems have been developed to overcome ocular barriers in order to improve drug efficacy. We have previously reported that montmorillonite (MT) microspheres (MPs) and solid lipid nanoparticles (SLNs) loaded with the anti-glaucoma drug betaxolol hydrochloride (BHC) exhibited sustained drug release and thus intraocular pressure (IOP) lowering effects. Here, we investigated the effect of physicochemical particle parameters on the micro-interactions with tear film mucins and corneal epithelial cells. Results showed that the MT-BHC SLNs and MT-BHC MPs eye drops significantly prolonged the precorneal retention time due to their higher viscosity and lower surface tension and contact angle compared with the BHC solution, with MT-BHC MPs exhibiting the longest retention due to their stronger hydrophobic surface. The cumulative release of MT-BHC SLNs and MT-BHC MPs was up to 87.78% and 80.43% after 12 h, respectively. Tear elimination pharmacokinetics study further confirmed that the prolonged precorneal retention time of the formulations was due to the micro-interaction between the positively charged formulations and the negatively charged tear film mucins. Moreover, the area under the IOP reduction curve (AUC) of MT-BHC SLNs and MT-BHC MPs was 1.4 and 2.5 times that of the BHC solution. Accordingly, the MT-BHC MPs also exhibit the most consistent and long-lasting IOP-lowering effect. Ocular irritation experiments showed no significant toxicity of either. Taken together, MT MPs may have the potential for more effective glaucoma treatment.
Topics: Drug Delivery Systems; Eye; Betaxolol; Bentonite; Drug Liberation
PubMed: 36866574
DOI: 10.1080/10717544.2023.2184312 -
Molecules (Basel, Switzerland) Nov 2023In recent years, the coagulation properties of inorganic minerals such as kaolin and zeolite have been demonstrated. This study aimed to assess the hemostatic properties...
In recent years, the coagulation properties of inorganic minerals such as kaolin and zeolite have been demonstrated. This study aimed to assess the hemostatic properties of three local clays from China: natural kaolin from Hainan, natural halloysite from Yunnan, and zeolite synthesized by our group. The physical and chemical properties, blood coagulation performance, and cell biocompatibility of the three materials were tested. The studied materials were characterized by using scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), X-ray fluorescence spectroscopy (XRF), thermogravimetric analysis (TGA), and differential scanning calorimetry (DSC). All three clays showed different morphologies and particle size, and exhibited negative potentials between pH 6 and 8. The TGA and DSC curves for kaolin and halloysite were highly similar. Kaolin showed the highest water absorption capacity (approximately 93.8% ± 0.8%). All three clays were noncytotoxic toward L929 mouse fibroblasts. Kaolin and halloysite showed blood coagulation effects similar to that exhibited by zeolite, indicating that kaolin and halloysite are promising alternative hemostatic materials.
Topics: Animals; Mice; Clay; Kaolin; Zeolites; China; Hemostatics
PubMed: 38067486
DOI: 10.3390/molecules28237756 -
Environmental Pollution (Barking, Essex... Jul 2023Selenium (Se) amendment could reduce mercury (Hg) bioaccumulation in crops, but sometimes it could cause excessive Se accumulation in crops and potential Se exposure...
Selenium (Se) amendment could reduce mercury (Hg) bioaccumulation in crops, but sometimes it could cause excessive Se accumulation in crops and potential Se exposure risks for humans. In this study, we designed and synthesized selenium and sulfur-modified montmorillonite materials (Se/S-Mont) to effectively reduce mercury levels and avoid excessive Se enrichment in plants. The results of pot experiments (1 g Se/S-Mont/100 g soil) and field microplot trials (0.3 g Se/S-Mont/100 g soil, 8 t/ha) showed that Se/S-Mont amendments significantly reduced the Hg concentrations in water spinach and hybrid Pennisetum by 28-68% and 57%-92% (P < 0.05), respectively, while they did not lead to excessive Se bioaccumulation in the plants. Se/S-Mont was more efficient in mitigating soil Hg pollution than adding raw materials (e.g., NaSeO₃) and their combinations, and they significantly reduced the available Se fraction in the soil and the Se levels in the plants (P < 0.05). The potential mechanisms revealed by X-ray absorption near-edge spectra (XANES) and pot experiments were the adsorption and slow release of Hg, S, and Se by Se/S-Mont, the high affinity between Hg and Se, competition between Se and S, and the formation of stable complexes containing Se-S-Hg. The Se/S-Mont immobilizer was easy to prepare and required the application of small amounts, and the remediation effect was relatively stable and exhibited few negative effects; therefore, the approach showed high environmental and economic potentials.
Topics: Humans; Mercury; Selenium; Bentonite; Farms; Soil; Sulfur
PubMed: 37105467
DOI: 10.1016/j.envpol.2023.121719 -
Asian Pacific Journal of Cancer... Nov 2023Grape hybrids are characterized by different chemical compositions; often with high hybrids are characterized by different chemical compositions, often with a high...
Antiproliferative and Apoptosis Effects of Hybrid Varieties of Vitis vinifera L. Sweet Sapphire and Sweet Surprise on Human Prostate Cancer Cells Using In Vitro and In Silico Approaches.
OBJECTIVE
Grape hybrids are characterized by different chemical compositions; often with high hybrids are characterized by different chemical compositions, often with a high phenolic content and a specific profile of anthocyanins. The aim of study was to characterize the constituents of hybrid Vitis vinifera L. varieties Sweet Sapphire (SA) and Sweet Surprise (SU) extracts and their influence on apoptosis induction and antiproliferative effects on human prostate cancer cells.
METHODS
We used the MTT assay to evaluate the cytotoxic effect of extracts of SA and SU, on the prostate adenocarcinoma cell lines PC-3 and DU-145. To analyze the inhibiting impact by flow cytometry, used 24 and 48 hours. Anthocyanins were quantified by liquid chromatography and analysed by their absorption rate, hepatotoxicity, blood concentration, blood-brain barrier passage ability and maximum recommended dose by in silico approaches.
RESULTS
Our results showed that malvidin derivatives present the highest content in both cultivars. We identified 14.46mg/100g malvidin-3-O-glycoside in SA and 2.76 mg/100 g in SU. A reduction in cell viability of DU-145 (45 and 65%) and PC-3 (63 and 67%) cells after 48h treatment with SA and SU, respectively, was found via MTT assay. Flow cytometry showed that the treatment with extracts from SA and SU had an inhibitory impact on cell development due to G2/M arrest and caused a rise in apoptotic cells compared to control group. None of the anthocyanin presented hepatotoxicity as well as blood-brain barrier passage ability. Peonidin 3-O-glucoside had the lower maximum recommended dose as well as the highest intestinal absorption rate. However, delphinidin 3-O-glucoside had the highest blood concentration values.
CONCLUSION
The findings of this study highlight the potential of hybrid Vitis vinifera L. varieties as an important source of natural antioxidants and their protective effect against prostate cancer cells as well as elucidate in part their anthocyanin's metabolism.
Topics: Male; Humans; Apoptosis; Anthocyanins; Vitis; Cell Line, Tumor; G2 Phase Cell Cycle Checkpoints; Prostatic Neoplasms; Aluminum Oxide; Glucosides; Chemical and Drug Induced Liver Injury
PubMed: 38019224
DOI: 10.31557/APJCP.2023.24.11.3673 -
The International Journal of... Oct 2023To investigate the effects of airborne-particle abrasion and nanosilica (nano-Si) infiltration treatment on the surface characteristics of dental zirconia.
PURPOSE
To investigate the effects of airborne-particle abrasion and nanosilica (nano-Si) infiltration treatment on the surface characteristics of dental zirconia.
MATERIALS AND METHODS
A total of 15 unsintered zirconia ceramic green bodies (10 × 10 × 3 mm) were divided into three groups (n = 5): Group C, no treatment after sintering; Group S, airborne-particle abrasion with 50-μm aluminum oxide particles after sintering; and Group N, infiltration of nano-Si followed by sintering and hydrofluoric acid (HF) etching. The zirconia disks' surface roughness was analyzed by atomic force microscopy (AFM). The surface morphology of the specimens was analyzed using scanning electron microscopy (SEM), and the chemical composition was analyzed by energy-dispersive x-ray (EDX). Data were statistically analyzed by the Kruskal-Wallis test (P < .05).
RESULTS
Zirconia surface treatments by infiltration of nano-Si, sintering, and HF etching showed multiple changes in the surface features. The surface roughness of Groups C, S, and N were 0.88 ± 0.07 μm, 1.26 ± 0.10 μm, and 1.69 ± 0.15 μm, respectively. The surface roughness of Group N was significantly higher than that of Groups C and S (P < .05). EDX analysis showed peaks that corresponded to silica (Si) after infiltration with colloidal Si that disappeared following acid etching.
CONCLUSIONS
Infiltrating nano-Si increases the surface roughness of zirconia. The formation of retentive nanopores on the surface potentially improves the zirconia-resin cement bonding strengths.
Topics: Humans; Dental Bonding; Surface Properties; Ceramics; Zirconium; Resin Cements; Aluminum Oxide; Materials Testing; Microscopy, Electron, Scanning; Dental Etching
PubMed: 37879051
DOI: 10.11607/prd.6318 -
Journal of Controlled Release :... Jan 2024Zeolite imidazolate framework-8 (ZIF-8) is a biomaterial that has been increasingly studied in recent years. It has several applications such as bone regeneration,... (Review)
Review
Zeolite imidazolate framework-8 (ZIF-8) is a biomaterial that has been increasingly studied in recent years. It has several applications such as bone regeneration, promotion of angiogenesis, drug loading, and antibacterial activity, and exerts multiple effects to deal with various problems in the process of bone regeneration. This systematic review aims to provide an overview of the applications and effectiveness of ZIF-8 in bone regeneration. A search of papers published in the PubMed, Web of Science, Embase, and Cochrane Library databases revealed 532 relevant studies. Title, abstract, and full-text screening resulted in 39 papers being included in the review, including 39 in vitro and 22 animal studies. Appropriate concentrations of nano ZIF-8 can promote cell proliferation and osteogenic differentiation by releasing Zn and entering the cell, whereas high doses of ZIF-8 are cytotoxic and inhibit osteogenic differentiation. In addition, five studies confirmed that ZIF-8 exhibits good vasogenic activity. In all in vivo experiments, nano ZIF-8 promoted bone formation. These results indicate that, at appropriate concentrations, materials containing ZIF-8 promote bone regeneration more than materials without ZIF-8, and with characteristics such as promoting angiogenesis, drug loading, and antibacterial activity, it is expected to show promising applications in the field of bone regeneration. STATEMENT OF SIGNIFICANCE: This manuscript reviewed the use of ZIF-8 in bone regeneration, clarified the biocompatibility and effectiveness in promoting bone regeneration of ZIF-8 materials, and discussed the possible mechanisms and factors affecting its promotion of bone regeneration. Overall, this study provides a better understanding of the latest advances in the field of bone regeneration of ZIF-8, serves as a design guide, and contributes to the design of future experimental studies.
Topics: Animals; Osteogenesis; Zeolites; Bone Regeneration; Biocompatible Materials; Anti-Bacterial Agents
PubMed: 38042375
DOI: 10.1016/j.jconrel.2023.11.049 -
Environmental Pollution (Barking, Essex... Jun 2024The effects of metal oxides and clays on the transport of zinc oxide nanoparticles (ZnO-NPs) in saturated porous media were investigated under different ionic strength...
The effects of metal oxides and clays on the transport of zinc oxide nanoparticles (ZnO-NPs) in saturated porous media were investigated under different ionic strength (IS) conditions. We studied the transport and retention behavior of ZnO-NPs for different types of porous media (untreated, acid treated, and acid-salt treated sand). The selected untreated sand was used as a representative sand, coated with both metal oxide and clay. The acid treated and acid-salt-treated sands were used and compared to investigate the effects of clays on the surface of the sand. In addition, the effects of clay particles in bulk solutions on the mobility and retention of ZnO-NPs were observed using bentonite as a representative clay particle. We found that the increased mobility of positively charged ZnO-NPs can be attributed to increasing charge heterogeneity of silica sand with metal oxides (mainly, iron oxide) and clays in untreated sand. No breakthrough of ZnO-NP was observed for acid-treated (presence of clays and absence of metal oxides) and acid-salt-treated sand (absence of both metal oxide and clays). Most of the injected ZnO-NPs were deposited on the surface of the sand near the column inlet. The transport of bentonite-facilitated ZnO-NPs was improved at the lowest IS (0.1 mM) (∼20%), whereas there was no difference in the mobility of ZnO-NPs at high IS solutions (1 mM and 10 mM). In particular, the breakthrough amount improved with increasing bentonite concentration. Classical Derjaguin-Landau-Verwey-Overbeek interactions help explain observed interactions between ZnO-NPs and sand as well as bentonite and sand.
Topics: Zinc Oxide; Clay; Porosity; Metal Nanoparticles; Oxides; Bentonite; Aluminum Silicates; Sand; Nanoparticles
PubMed: 38677461
DOI: 10.1016/j.envpol.2024.124007 -
Scientific Reports Oct 2023A Ga-substituted spinel magnetite nanoparticles (NPs) with the formula GaFeO were synthesized using both the one-pot solvothermal decomposition method (TD) and the...
A Ga-substituted spinel magnetite nanoparticles (NPs) with the formula GaFeO were synthesized using both the one-pot solvothermal decomposition method (TD) and the microwave-assisted heating method (MW). Stable colloidal solutions were obtained by using triethylene glycol, which served as a NPs stabilizer and as a reaction medium in both methods. A narrow size distribution of NPs, below 10 nm, was achieved through selected nucleation and growth. The composition, structure, morphology, and magnetic properties of the NPs were investigated using FTIR spectroscopy, thermal analysis (TA), X-ray diffraction (XRD), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), and magnetic measurements. NPs with the expected spinel structure were obtained in the case of the TD method, while the MW method produced, additionally, an important amount of gallium suboxide. The NPs, especially those prepared by TD, have superparamagnetic behavior with 2.02 μB/f.u. at 300 K and 3.06 μB/f.u. at 4.2 K. For the MW sample these values are 0.5 μB/f.u. and 0.6 μB/f.u. at 300 K and 4.2 K, respectively. The MW prepared sample contains a secondary phase and very small NPs which affects both the dimensional distribution and the magnetic behavior of NPs. The NPs were tested in vitro on amniotic mesenchymal stem cells. It was shown that the cellular metabolism is active in the presence of GaFeO NPs and preserves an active biocompatible cytoskeleton.
Topics: Aluminum Oxide; Magnesium Oxide; Magnetite Nanoparticles; Spectroscopy, Fourier Transform Infrared
PubMed: 37875541
DOI: 10.1038/s41598-023-45285-y -
European Review For Medical and... Oct 2023To evaluate the effects of various surface pretreatment methods, including H2SO4, Riboflavin, and Al2O3, as well as different luting cement types, namely Methyl... (Randomized Controlled Trial)
Randomized Controlled Trial
The impact of PEEK pretreatment using H2SO4, riboflavin, and aluminum trioxide on the extrusion bond strength to canal dentin luted with Polymethyl methacrylate and resin-based composite cement.
OBJECTIVE
To evaluate the effects of various surface pretreatment methods, including H2SO4, Riboflavin, and Al2O3, as well as different luting cement types, namely Methyl Methacrylate based Cement (MMBC) and composite-based cement (CBC), on the extrusion bond strength (EBS) of poly-ether-ether-ketone (PEEK) posts bonded to canal dentin.
MATERIALS AND METHODS
This study involved 120 single-rooted human premolar teeth that underwent endodontic treatment. Following root canal preparation, PEEK posts were fabricated from PEEK blanks using a CAD-CAM system, resulting in a total of 120 posts. The posts were randomly assigned to one of four groups based on their post-surface conditioning: Group A H2SO4, Group B RF, Group C Al2O3, and Group D (NC), each consisting of 30 posts. Within each group, there were two subgroups based on the type of luting cement used for bonding. Subgroups A1, B1, C1, and D1 (n=15 each) utilized CBC, while Subgroups A2, B2, C2, and D2 (n=15 each) used MMBC.The bond strength between the PEEK posts and root dentin was assessed using a universal testing machine, and the failure modes were examined under a stereomicroscope. Statistical analysis, including one-way analysis of variance (ANOVA) and Tukey's Post Hoc test with a significance level of p=0.05, was performed to analyze the data and evaluate the effects of surface treatment and luting cement type on the bond strength.
RESULTS
Group B2, which underwent RF conditioning followed by Super-Bond C&B cement application, exhibited the highest bond strength scores at the coronal section (9.57±0.67 MPa). On the other hand, Group D1, which had no conditioning (NC) and used Panavia® V5 cement, showed the lowest EBS at the apical third (2.39±0.72 MPa). The overall results indicate that the different conditioning regimens and luting cement types did not significantly influence the bond strength of PEEK posts to root dentin (p>0.05).
CONCLUSIONS
Riboflavin activated by photodynamic therapy (PDT) and H2SO4 can be effective surface conditioners for PEEK posts. These treatments have shown potential for enhancing the bond strength between PEEK and resin cement. Additionally, the study revealed that MMA-based cement outperformed composite-based cement in terms of bond integrity with PEEK posts.
Topics: Humans; Aluminum; Aluminum Oxide; Bone Cements; Composite Resins; Dentin; Ether; Ethers; Ethyl Ethers; Glass; Ketones; Materials Testing; Polymethyl Methacrylate; Riboflavin
PubMed: 37916329
DOI: 10.26355/eurrev_202310_34135