-
CNS Spectrums Dec 2023Problems with cognitive flexibility have been associated with multiple psychiatric disorders, but there has been little understanding of how cognitive flexibility...
OBJECTIVE
Problems with cognitive flexibility have been associated with multiple psychiatric disorders, but there has been little understanding of how cognitive flexibility compares across these disorders. This study examined problems of cognitive flexibility in young adults across a range of psychiatric disorders using a validated computerized -diagnostic flexibility paradigm. We hypothesized that obsessive-compulsive spectrum disorders (eg, obsessive-compulsive disorder, trichotillomania, and skin-picking disorder) would be associated with pronounced flexibility problems as they are most often associated with irrational or purposeless repetitive behaviors.
METHODS
A total of 576 nontreatment seeking participants (aged 18-29 years) were enrolled from general community settings, provided demographic information, and underwent structured clinical assessments. Each participant undertook the intra-extra-dimensional task, a validated computerized test measuring set-shifting ability. The specific measures of interest were total errors on the task and performance on the extra-dimensional (ED) shift, which reflects the ability to inhibit and shift attention away from one stimulus dimension to another.
RESULTS
Participants with depression and PTSD had elevated total errors on the task with moderate effect sizes; and those with the following had deficits of small effect size: generalized anxiety disorder (GAD), obsessive-compulsive disorder (OCD), antisocial personality disorder, and binge-eating disorder. For ED errors, participants with PTSD, GAD, and binge-eating disorder exhibited deficits with medium effect sizes; those with the following had small effect size deficits: depression, social anxiety disorder, OCD, substance dependence, antisocial personality disorder, and gambling disorder.
CONCLUSIONS
These data indicate cognitive flexibility deficits occur across a range of mental disorders. Future work should explore whether these deficits can be ameliorated with novel treatment interventions.
Topics: Young Adult; Humans; Obsessive-Compulsive Disorder; Trichotillomania; Anxiety Disorders; Cognition; Attention
PubMed: 37114560
DOI: 10.1017/S1092852923002237 -
Current Psychiatry Reports Nov 2023Despite significant negative outcomes, the co-occurrence of personality disorders (PDs) and substance use disorders (SUDs) continues to be underrecognized, and the... (Review)
Review
PURPOSE OF REVIEW
Despite significant negative outcomes, the co-occurrence of personality disorders (PDs) and substance use disorders (SUDs) continues to be underrecognized, and the mechanisms contributing to this co-occurrence remain unclear. This review summarizes recent work on PD-SUD co-occurrence, with a focus on borderline and antisocial PDs, general substance use patterns among those with PDs, and the association of personality traits with SUDs.
RECENT FINDINGS
The prevalence of co-occurring PD-SUD is generally high, with estimates ranging depending on the type of PD and SUD, the population assessed, and the sampling methods and measures used. Current theoretical explanations for co-occurrence include shared etiology and predisposition models, with research highlighting the importance of transactional processes. Potential underlying mechanisms include personality traits and transdiagnostic characteristics. Recent research has increased focus on substances besides alcohol, dimensional models of personality pathology, and transactional explanations of co-occurrence, but more research is needed to disentangle the nuanced PD-SUD relationship.
Topics: Humans; Comorbidity; Personality Disorders; Substance-Related Disorders; Personality; Prevalence
PubMed: 37787897
DOI: 10.1007/s11920-023-01452-6 -
Prevention Science : the Official... Nov 2023Adolescence is a critical period during which youth develop and shape their behaviors. Because differences between youths are strongly connected to environmental...
Adolescence is a critical period during which youth develop and shape their behaviors. Because differences between youths are strongly connected to environmental factors, we aimed to elucidate possible pathways from home-school regulation and atmosphere to youths' prosocial and antisocial behaviors. Data were derived from the China Education Panel Survey. This study involved a total of 9291 students aged 14-15 years (4834 boys, 4457 girls). We used structural equation modeling (SEM) with LISREL 8.80 and Monte Carlo resampling with R to conduct the analysis strategy. In the home-school regulation, parental supervision on the one hand and teacher criticism on the other hand have direct positive and negative predictive effects on youths' prosocial behaviors, respectively, while their direct effects on antisocial behavior are the opposite; teachers praise does not directly affect adolescents' prosocial and antisocial behaviors. In the home-school atmosphere, family interaction and perceived good class climate directly positively affect youths' prosocial behaviors, while the direct effects of both on antisocial behavior are not significant. The SEM results reveal that academic self-efficacy and depressive symptoms may be underlying mediating mechanisms through which home-school regulation and atmosphere during adolescence affect students' prosocial and antisocial behaviors. Intervention programs targeting home-school supportive environments and prevention programs targeting positive emotion and self-awareness may yield benefits for proper social behavior in adolescents. For example, by enhancing the way and frequency of parent-child interaction, teachers and students jointly create a good class climate of care and friendship to strengthen a home-school supportive environment. Improve adolescents' positive emotions such as contentment, optimism, and hope to reduce the possibility of depression.
PubMed: 37940781
DOI: 10.1007/s11121-023-01611-4 -
The International Journal of Social... Sep 2023Homeless people present high rates of psychopathology, including personality disorders. Given the link between personality disorders and attachment, and the potential... (Review)
Review
BACKGROUND
Homeless people present high rates of psychopathology, including personality disorders. Given the link between personality disorders and attachment, and the potential importance of these two traits for understanding homeless populations.
AIMS
Our aim was to review all studies focusing on attachment and on the full assessment of personality disorders in the homeless.
METHOD
Overall, 213 studies were screened through title and abstract. Of these, 63 articles were chosen for full-text assessment.
RESULTS
A total of 14 articles met eligibility criteria and were included in the present review. Six studies evaluated personality disorders and eight studies assessed attachment in the homeless. In general, reports suggested that personality disorders are highly common in the homeless, with frequencies ranging between 64% and 79% for any personality disorder. The most common personality diagnoses were paranoid (14%-74%), borderline (6%-62%), avoidant (14%-63%), and antisocial (4%-57%) personality disorders. Attachment reports differed in the methods used and presented diverse results and correlates. Even so, insecure types of attachment dominated in the homeless, accounting for 62% to 100% of the samples.
CONCLUSIONS
The high prevalence of personality disorders and insecure types of attachment in the homeless may impact intervention strategies for these people. The available literature evaluating attachment and the full assessment of personality disorders in the homeless is scarce, which supports the need for more research on these two topics.
Topics: Humans; Personality Disorders; Psychopathology; Ill-Housed Persons; Prevalence; Personality; Borderline Personality Disorder
PubMed: 36951386
DOI: 10.1177/00207640231161201 -
Trends in Cognitive Sciences Feb 2024Antisocial behaviour (ASB) incurs substantial costs to the individual and society. Cognitive neuroscience has the potential to shed light on developmental risk for ASB,... (Review)
Review
Antisocial behaviour (ASB) incurs substantial costs to the individual and society. Cognitive neuroscience has the potential to shed light on developmental risk for ASB, but it cannot achieve this potential in an 'essentialist' framework that focuses on the brain and cognition isolated from the environment. Here, we present the case for studying the social transactional and iterative unfolding of brain and cognitive development in a relational context. This approach, which we call the study of the 'embedded brain', is needed to fully understand how risk for ASB arises during development. Concentrated efforts are required to develop and unify methods to achieve this approach and reap the benefits for improved prevention and intervention of ASB.
Topics: Humans; Antisocial Personality Disorder; Conduct Disorder; Brain; Behavior Therapy; Emotions
PubMed: 37718176
DOI: 10.1016/j.tics.2023.08.013 -
Administration and Policy in Mental... May 2024Previous research indicates that youth exhibiting antisocial behavior are at risk for utilizing a disproportionate amount of health services compared to youth without...
Previous research indicates that youth exhibiting antisocial behavior are at risk for utilizing a disproportionate amount of health services compared to youth without these problems. The present study investigates whether being processed by the juvenile justice system and showing callous-unemotional (CU) traits independently predict health service utilization (medical and mental health service use and out-of-home placement) over and above the severity of antisocial behavior across adolescence. A total of 766 participants who had been arrested for the first time in adolescence provided data at ten appointments over a period of seven years. Results showed that self-reported antisocial behavior at the time of arrest predicted increased use of most health service use types over the next seven years (i.e. medicine prescriptions, tests for sexually transmitted infections, mental health service appointments, and out-of-home placements). All except prescription medication use remained significant when controlling for justice system processing and CU traits. Further, justice system processing added significantly to the prediction of medical service appointments. Whereas CU traits were associated with mental health service appointments and out-of-home placements, these did not remain significant when controlling for severity of antisocial behavior. These findings are consistent with prior research documenting the health care costs of antisocial behavior.
Topics: Humans; Adolescent; Male; Female; Juvenile Delinquency; Mental Health Services; Antisocial Personality Disorder; Emotions; Patient Acceptance of Health Care
PubMed: 38427148
DOI: 10.1007/s10488-024-01341-x -
Social Neuroscience Aug 2023Preverbal infants appear to be more attracted by prosocial characters and events, as typically assessed using preferential looking times and manual choice. However,...
Preverbal infants appear to be more attracted by prosocial characters and events, as typically assessed using preferential looking times and manual choice. However, infants' neural correlates of observed prosocial and antisocial interactions are still scarce. Here, we familiarized 5-month-old ( = 24) infants with a prosocial and antisocial scene (i.e., a character either helping or hindering) and infants' Event-Related Potentials (ERP) were recorded in response to the presentation of short video clips of the prosocial and antisocial interaction. On a neural level, results revealed that infants could discriminate between helping and hindering events at an early stage of processing, as shown by a larger N290 response to the former compared to the latter. Further, while the Nc - typically indexing attentional processes - was larger for antisocial over prosocial events, the LPP, indexing cognitive evaluation of the stimuli, was larger for prosocial over antisocial actions. Finally, infants' higher scores on the effortful control temperamental subscale were related to infants' increased N290 neural sensitivity to antisocial scenes. Together, these findings provide new evidence of the time course of infants' ERP responses during the observation of helping and hindering interactions, which involves both attentional and socially relevant processes.
Topics: Humans; Infant; Social Behavior; Evoked Potentials
PubMed: 37610285
DOI: 10.1080/17470919.2023.2245597 -
The British Journal of Social Psychology Jul 2023Research from the social sciences suggests an association between higher temperatures and increases in antisocial behaviours, including aggressive, violent, or... (Meta-Analysis)
Meta-Analysis Review
Research from the social sciences suggests an association between higher temperatures and increases in antisocial behaviours, including aggressive, violent, or sabotaging behaviours, and represents a heat-facilitates-aggression perspective. More recently, studies have shown that higher temperature experiences may also be linked to increases in prosocial behaviours, such as altruistic, sharing, or cooperative behaviours, representing a warmth-primes-prosociality view. However, across both literatures, there have been inconsistent findings and failures to replicate key theoretical predictions, leaving the status of temperature-behaviour links unclear. Here we review the literature and conduct meta-analyses of available empirical studies that have either prosocial (e.g., monetary reward, gift giving, helping behaviour) or antisocial (self-rewarding, retaliation, sabotaging behaviour) behavioural outcome variables, with temperature as an independent variable. In an omnibus multivariate analysis (total N = 4577) with 80 effect sizes, we found that there was no reliable effect of temperature on the behavioural outcome measured. Further, we find little support for either the warmth-primes-prosociality view or the heat-facilitates-aggression view. There were no reliable effects if we consider separately the type of behavioural outcome (prosocial or antisocial), different types of temperature experience (haptic or ambient), or potential interactions with the experimental social context (positive, neutral, or negative). We discuss how these findings affect the status of existing theoretical perspectives and provide specific suggestions advancing research in this area.
Topics: Humans; Social Behavior; Temperature; Antisocial Personality Disorder; Aggression; Cognition
PubMed: 36794795
DOI: 10.1111/bjso.12626 -
PLOS Global Public Health 2023Prior research has demonstrated an association between lead exposure and criminal behavior at the population-level, however studies exploring the effect of lead exposure...
Prior research has demonstrated an association between lead exposure and criminal behavior at the population-level, however studies exploring the effect of lead exposure on criminal behavior at the individual-level have not been reviewed systematically. The intent of this study is to complete a systematic review of all studies assessing individual-level exposures to lead and the outcomes of crime and antisocial behavior traits. We included peer reviewed studies that were published prior to August 2022 and were classified as cohort, cross-sectional, or case-control. Studies measuring the outcomes of crime, delinquency, violence, or aggression were included. The following databases were searched using a standardized search strategy: ProQuest Environmental Science Database, PubMed, ToxNet and the Public Affairs Information Service (PAIS). Seventeen manuscripts met our inclusion criteria. Blood lead was measured in 12 studies, bone lead in 3 studies, and dentine lead levels in 2 studies. This systematic review identified a wide range of diverse outcomes between exposure to lead at multiple windows of development and later delinquent, criminal and antisocial behavior. A review of all potential confounding variables included within each study was made, with inclusion of relevant confounders into the risk of bias tool. There is limited data at the individual level on the effects of prenatal, childhood, and adolescent lead exposure and later criminal behavior and more evidence is necessary to evaluate the magnitude of the associations seen in this review. Our review, in conjunction with the available biological evidence, suggests that an excess risk for criminal behavior in adulthood exists when an individual is exposed to lead in utero or in the early years of childhood. The authors report no conflict of interest and no funding source. Clinical trial registration: PROSPERO ID: CRD42021268379.
PubMed: 37527230
DOI: 10.1371/journal.pgph.0002177 -
Acta Psychiatrica Scandinavica Sep 2023Childhood trauma (CT) is associated with severe sequelae, including stress-related mental health disorders that can perpetuate long into adulthood. A key mechanism in...
BACKGROUND
Childhood trauma (CT) is associated with severe sequelae, including stress-related mental health disorders that can perpetuate long into adulthood. A key mechanism in this relationship seems to be emotion regulation. We aimed to investigate (1) whether childhood trauma is associated with anger in adulthood, and, if so, (2) to explore which types of childhood trauma predominate in the prediction of anger in a cohort that included participants with and without current affective disorders.
METHODS
In the Netherlands Study of Depression and Anxiety (NESDA), childhood trauma was assessed with a semi-structured Childhood Trauma Interview (CTI) at baseline, and analyzed in relation to anger as measured at a 4-year follow-up with the Spielberger Trait Anger Subscale (STAS), the Anger Attacks Questionnaire, and cluster B personality traits (i.e., borderline, antisocial) of the Personality Disorder Questionnaire 4 (PDQ-4), using analysis of covariance (ANCOVA) and multivariable logistic regression analyses. Post hoc analyses comprised cross-sectional regression analyses, using the Childhood Trauma Questionnaire-Short Form (CTQ-SF) also obtained at a 4-year follow-up.
RESULTS
Participants (n = 2271) were on average 42.1 years (SD = 13.1), and 66.2% were female. Childhood trauma showed a dose-response association with all anger constructs. All types of childhood trauma were significantly associated with borderline personality traits, independently of depression and anxiety. Additionally, all types of childhood trauma except for sexual abuse were associated with higher levels of trait anger, and a higher prevalence of anger attacks and antisocial personality traits in adulthood. Cross-sectionally, the effect sizes were larger compared with the analyses with the childhood trauma measured 4 years prior to the anger measures.
CONCLUSIONS
Childhood trauma is linked with anger in adulthood, which could be of particular interest in the context of psychopathology. Focus on childhood traumatic experiences and adulthood anger may help to enhance the effectiveness of treatment for patients with depressive and anxiety disorders. Trauma-focused interventions should be implemented when appropriate.
Topics: Humans; Adult; Female; Male; Cross-Sectional Studies; Adverse Childhood Experiences; Anxiety Disorders; Anxiety; Anger; Surveys and Questionnaires
PubMed: 37430486
DOI: 10.1111/acps.13589