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International Journal of Molecular... May 2024The field of dental materials is rapidly evolving, and this Special Issue of the offers a comprehensive examination of the latest advancements in process design and...
The field of dental materials is rapidly evolving, and this Special Issue of the offers a comprehensive examination of the latest advancements in process design and development strategies [...].
Topics: Dental Materials; Humans
PubMed: 38791097
DOI: 10.3390/ijms25105057 -
ACS Biomaterials Science & Engineering Aug 2023Photoactivating dental resin composites have been the most prevailing material for repairing dental defects in various clinical scenarios due to their multiple...
Photoactivating dental resin composites have been the most prevailing material for repairing dental defects in various clinical scenarios due to their multiple advantages. However, compared to other restorative materials, the surface of resin-based composites is more susceptible to plaque biofilm accumulation, which can lead to secondary caries and restoration failure. This study introduced different weight fractions (1, 2, 5, 10, and 15%) of magnesium oxide nanoparticles (MgONPs) as antibacterial fillers into dental resin composites. Multifarious properties of the material were investigated, including antibacterial activity against a human salivary plaque-derived biofilm, cytotoxicity on human gingival fibroblasts, mechanical and physicochemical properties as well as the performance when subjected to thermocycling aging treatment. Results showed that the incorporation of MgONPs significantly improved the composites' anti-biofilm capability even at a low amount of 2 wt % without compromising the mechanical, physicochemical, and biocompatibility performances. The results of the thermocycling test suggested certain of aging resistance. Moreover, a small amount of MgONPs possibly made a difference in enhancing photoactivated polymerization and increasing the curing depth of experimental resin composites. Overall, this study highlights the potential of MgONPs as an effective strategy for developing antibacterial resin composites, which may help mitigating cariogenic biofilm-associated secondary caries.
Topics: Humans; Materials Testing; Magnesium Oxide; Composite Resins; Nanoparticles; Anti-Bacterial Agents
PubMed: 37486960
DOI: 10.1021/acsbiomaterials.3c00490 -
Dental Materials : Official Publication... May 2024The objective was to discuss the research on zirconia published in the past 15 years to help the dental materials community understand the key properties of the types of... (Review)
Review
OBJECTIVES
The objective was to discuss the research on zirconia published in the past 15 years to help the dental materials community understand the key properties of the types of zirconia and their clinical applications.
METHODS
A literature search was performed in May/2023 using Web of Science Core Collection with the term "dental zirconia". The search returned 5102 articles, which were categorized into 31 groups according to the research topic.
RESULTS
The current approach to improving the translucency of zirconia is to decrease the alumina content while increasing the yttria content. The resulting materials (4Y-, 5Y-, and above 5 mol% PSZs) may contain more than 50% of cubic phase, with a decrease in mechanical properties. The market trend for zirconia is the production of CAD/CAM disks containing more fracture resistant 3Y-TZP at the bottom layers and more translucent 5Y-PSZ at the top. Although flaws located between layers in multilayered blocks might represent a problem, newer generations of zirconia layered blocks appear to have solved this problem with novel powder compaction technology. Significant advancements in zirconia processing technologies have been made, but there is still plenty of room for improvement, especially in the fields of high-speed sintering and additive manufacturing.
SIGNIFICANCE
The wide range of zirconia materials currently available in the market may cause confusion in materials selection. It is therefore imperative for dental clinicians and laboratory technicians to get the needed knowledge on zirconia material science, to follow manufacturers' instructions, and to optimize the design of the prosthetic restoration with a good understanding where to reinforce the structure with a tough and strong zirconia.
Topics: Zirconium; Dental Materials; Computer-Aided Design; Surface Properties; Yttrium; Materials Testing
PubMed: 38521694
DOI: 10.1016/j.dental.2024.02.026 -
Journal of Dentistry Jul 2024To give a comprehensive review of advancement in dental ceramics, fabrication methods, and the challenges associated with clinical application. (Review)
Review
OBJECTIVES
To give a comprehensive review of advancement in dental ceramics, fabrication methods, and the challenges associated with clinical application.
DATA, SOURCES AND STUDY SELECTION
Researches on chemical composition, biomechanical behaviors, optical properties, bonding strategies and fabrication methods were included. The search of articles was independently conducted by two authors in the PubMed, Scopus, Medline and Web of Science.
CONCLUSIONS
Dental ceramics have shown significant advancements in terms of esthetics and function. However, improving fracture toughness without compromising optical properties remains a challenge. Repairing fractured zirconia or glass-matrix ceramic prostheses with the same material is difficult due to the sintering process. Developing innovative bonding techniques that provide strong and long-lasting bonding strength between ceramics and tooth structures poses a recurring obstacle.
CLINICAL SIGNIFICANCE
Despite the emergence of dental ceramics and fabrication techniques, certain limitations such as susceptibility to brittleness and fracture still exist. Therefore, the current review provided valuable information around the advanced dental ceramics in tooth repair. The laboratory test data and the clinical outcome are also presented in details, aiming to guide clinicians in making informed decisions regarding ceramic restorations.
Topics: Humans; Ceramics; Zirconium; Dental Materials; Dental Bonding; Dental Porcelain; Esthetics, Dental; Materials Testing; Dental Prosthesis Design
PubMed: 38729288
DOI: 10.1016/j.jdent.2024.105053 -
Compendium of Continuing Education in... Feb 2024Besides meticulous application of proper bonding protocols and clinical technique, the clinical success of direct resin-based restorations is dependent on the selection...
Besides meticulous application of proper bonding protocols and clinical technique, the clinical success of direct resin-based restorations is dependent on the selection of the appropriate restorative material, curing light, and, whenever certain contours of the tooth need to be rebuilt, matrix band system. All of these aspects have seen significant developments and improvements over the years, all geared toward increased clinical success and longevity. Highlighting some of these key developments, this article provides an update on resin-based composites, curing lights, and matrix bands.
Topics: Humans; Dental Care; Dental Materials
PubMed: 38289628
DOI: No ID Found -
Clinical Oral Implants Research Sep 2023Group-2 reviewed the scientific evidence in the field of «Technology». Focused research questions were: (1) additive versus subtractive manufacturing of implant...
OBJECTIVES
Group-2 reviewed the scientific evidence in the field of «Technology». Focused research questions were: (1) additive versus subtractive manufacturing of implant restorations; (2) survival, complications, and esthetics comparing prefabricated versus customized abutments; and (3) survival of posterior implant-supported multi-unit fixed dental prostheses.
MATERIALS AND METHODS
Literature was systematically screened, and 67 publications could be critically reviewed following PRISMA guidelines, resulting in three systematic reviews. Consensus statements were presented to the plenary where after modification, those were accepted.
RESULTS
Additively fabricated implant restorations of zirconia and polymers were investigated for marginal/internal adaptation and mechanical properties without clear results in favor of one technology or material. Titanium base abutments for screw-retained implant single crowns compared to customized abutments did not show significant differences concerning 1-year survival. PFM, veneered and monolithic zirconia implant-supported multi-unit posterior fixed dental prostheses demonstrated similar high 3-year survival rates, whereas veneered restorations exhibited the highest annual ceramic fracture and chipping rates.
CONCLUSIONS
For interim tooth-colored implant single crowns both additive and subtractive manufacturing are viable techniques. The clinical performance of additively produced restorations remains to be investigated. Implant single crowns on titanium base abutments show similar clinical performance compared to other type of abutments; however, long-term clinical data from RCTs are needed. The abutment selection should be considered already during the planning phase. Digital planning facilitates 3D visualization of the prosthetic design including abutment selection. In the posterior area, monolithic zirconia is recommended as the material of choice for multi-unit implant restorations to reduce technical complications.
Topics: Titanium; Dental Implants; Bone Screws; Ceramics
PubMed: 37750528
DOI: 10.1111/clr.14148 -
BMC Oral Health May 2024Dental resin-based composites are widely recognized for their aesthetic appeal and adhesive properties, which make them integral to modern restorative dentistry. Despite...
BACKGROUND
Dental resin-based composites are widely recognized for their aesthetic appeal and adhesive properties, which make them integral to modern restorative dentistry. Despite their advantages, adhesion and biomechanical performance challenges persist, necessitating innovative strategies for improvement. This study addressed the challenges associated with adhesion and biomechanical properties in dental resin-based composites by employing molecular docking and dynamics simulation.
METHODS
Molecular docking assesses the binding energies and provides valuable insights into the interactions between monomers, fillers, and coupling agents. This investigation prioritizes SiO and TRIS, considering their consistent influence. Molecular dynamics simulations, executed with the Forcite module and COMPASS II force field, extend the analysis to the mechanical properties of dental composite complexes. The simulations encompassed energy minimization, controlled NVT and NPT ensemble simulations, and equilibration stages. Notably, the molecular dynamics simulations spanned a duration of 50 ns.
RESULTS
SiO and TRIS consistently emerged as influential components, showcasing their versatility in promoting solid interactions. A correlation matrix underscores the significant roles of van der Waals and desolvation energies in determining the overall binding energy. Molecular dynamics simulations provide in-depth insights into the mechanical properties of dental composite complexes. HEMA-SiO-TRIS excelled in stiffness, BisGMA-SiO-TRIS prevailed in terms of flexural strength, and EBPADMA-SiO-TRIS offered a balanced combination of mechanical properties.
CONCLUSION
These findings provide valuable insights into optimizing dental composites tailored to diverse clinical requirements. While EBPADMA-SiO-TRIS demonstrates distinct strengths, this study emphasizes the need for further research. Future investigations should validate the computational findings experimentally and assess the material's response to dynamic environmental factors.
Topics: Composite Resins; Molecular Dynamics Simulation; Molecular Docking Simulation; Silicon Dioxide; Biocompatible Materials; Dental Materials; Methacrylates; Polyurethanes; Polymethacrylic Acids; Polyethylene Glycols; Acrylic Resins
PubMed: 38735940
DOI: 10.1186/s12903-024-04343-1 -
Journal of Dentistry Sep 2023To review the literature on recurrent caries models used to evaluate restorative materials, compare reported methodology and parameters, and devise specific... (Review)
Review
OBJECTIVES
To review the literature on recurrent caries models used to evaluate restorative materials, compare reported methodology and parameters, and devise specific recommendations to be considered in future investigations.
DATA
The following were extracted: study design, sample characteristics, source of teeth, name of restorations compared including controls, recurrent caries model type, type of demineralizing and remineralizing solutions, type of biofilm used, methods to detect recurrent caries.
SOURCES
Literature searches were performed in OVID Medline, EMBASE, SCOPUS, and Cochrane Library.
STUDY SELECTION
For a study to be included, it had to examine dental materials for tooth restoration purposes only with a valid control group and evaluate restorative dental materials regardless of the form of the teeth caries model used or nature of the tooth structure used. A total of 91 studies were included. Most of the studies presented were in vitro. Human teeth were the main source of specimens utilized. Around 88% of the studies used specimens without an artificial gap, and 44% used a chemical model. S. mutans was the main bacterial species used in microbial caries models.
CONCLUSION
The findings of this review provided an insight into the performance of available dental materials assessed using different recurrent caries models, yet this review cannot be used as a guideline for material selection. Selecting the appropriate restorative material relies on several patient-related factors such as microbiota, occlusion, and diet that are not comprehensively taken into consideration in recurrent caries models and thus hinder reliable comparison.
CLINICAL SIGNIFICANCE
Due to the heterogenicity of variables among studies on the performance of dental restorative materials, this scoping review aimed to provide insights for dental researchers concerning the available recurrent caries models, testing methods used, and aspects of comparison between these materials including their characteristics and limitations.
Topics: Humans; Composite Resins; Dental Restoration, Permanent; Dental Caries Susceptibility; Dental Caries; Tooth, Deciduous
PubMed: 37419382
DOI: 10.1016/j.jdent.2023.104604 -
The Journal of Prosthetic Dentistry May 2024The increasing use of computer-aided design and computer-aided manufacturing (CAD-CAM) systems has led to the development of resin-ceramic materials that meet the... (Review)
Review
STATEMENT OF PROBLEM
The increasing use of computer-aided design and computer-aided manufacturing (CAD-CAM) systems has led to the development of resin-ceramic materials that meet the requirements of minimally invasive dentistry, including the resin nanoceramic (RNC) and polymer-infiltrated ceramic network (PICN). The wear characteristics of these materials are unclear.
PURPOSE
The purpose of this systematic review was to compare the wear resistance of resin-ceramic materials when compared with one another or with lithium disilicate glass-ceramics.
MATERIAL AND METHODS
The PubMed, Scopus, and DOSS search engines were used to identify articles published between 2013 and 2021. Two independent researchers conducted the systematic review by following the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines and by following a combination of keywords.
RESULTS
Of a total of 310 articles, 26 were selected, including only 1 clinical study. Among these, 15 compared resin-ceramic materials with each other, while 11 compared resin-ceramic materials with lithium disilicate ceramics. Two types of wear were used to compare the materials: attrition and abrasion. The most commonly studied materials were 2 RNCs (Lava Ultimate and Cerasmart), 1 PICN (Vita Enamic), and 1 ceramic (IPS e.max CAD). Among the resin-ceramic materials, the PICN (Vita Enamic) showed less wear than the RNCs. Of the RNCs, Cerasmart had less attrition wear and less wear of the opposing teeth.
CONCLUSIONS
Lithium disilicate glass-ceramics have a higher wear resistance than resin-ceramic materials, but they cause more wear of the opposing teeth.
Topics: Computer-Aided Design; Ceramics; Humans; Dental Porcelain; Dental Restoration Wear; Dental Materials; Resins, Synthetic
PubMed: 35459543
DOI: 10.1016/j.prosdent.2022.01.027 -
International Journal of Molecular... Dec 2023The dental material industry is rapidly developing resin-based composites (RBCs), which find widespread use in a variety of clinical settings. As such, their... (Review)
Review
The dental material industry is rapidly developing resin-based composites (RBCs), which find widespread use in a variety of clinical settings. As such, their biocompatibility has gained increasing interest. This literature review presents a summary of research into the cytotoxicity of methacrylate-based composites published from 2017 to 2023. Subject to analysis were 14 in vitro studies on human and murine cell lines. Cytotoxicity in the included studies was measured via MTT assay, LDH assay, and WST-1 assay. The QUIN Risk of Bias Tool was performed to validate the included studies. Included studies (based entirely on the results of in vitro studies) provide evidence of dose- and time-dependent cytotoxicity of dental resin-based composites. Oxidative stress and the depletion of cellular glutathione (GSH) were suggested as reasons for cytotoxicity. Induction of apoptosis by RBCs was indicated. While composites remain the golden standard of dental restorative materials, their potential cytotoxicity cannot be ignored due to direct long-term exposure. Further in vitro investigations and clinical trials are required to understand the molecular mechanism of cytotoxicity and produce novel materials with improved safety profiles.
Topics: Humans; Animals; Mice; Apoptosis; Biological Assay; Cell Line; Dental Materials; Glutathione
PubMed: 38203323
DOI: 10.3390/ijms25010152