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General diseases and medications in 687 patients reporting on adverse effects from dental materials.Clinical Oral Investigations Aug 2023Examination of patients claiming adverse effects from dental materials can be very challenging. Particularly, systemic aspects must be considered besides dental and...
OBJECTIVES
Examination of patients claiming adverse effects from dental materials can be very challenging. Particularly, systemic aspects must be considered besides dental and orofacial diseases and allergies. Therefore, the aim of this study was to investigate a cohort of 687 patients reporting on adverse effects from dental materials focusing on findings related to known general diseases or conditions or medication-related findings with relevance to their subjective complaints.
METHODS
Six hundred eighty-seven patients visiting a specialized consultation on claimed adverse effects from dental materials were retrospectively investigated for their subjective complaints, findings related to known general diseases or conditions, medication-related findings, dental and orofacial findings, or allergies with relevance to their subjective complaints.
RESULTS
The most frequent subjective complaints were burning mouth (44.1%), taste disorders (28.5%), and dry mouth (23.7%). In 58.4% of the patients, dental and orofacial findings relevant to their complaints could be found. Findings related to known general diseases or conditions or medication-related findings were found in 28.7% or 21.0% of the patients, respectively. Regarding medications, findings related to antihypertensives (10.0%) and psychotropic drugs (5.7%) were found most frequently. Relevant diagnosed allergies toward dental materials were found in 11.9%, hyposalivation in 9.6% of the patients. In 15.1% of the patients, no objectifiable causes for the expressed complaints could be found.
CONCLUSIONS
For patients complaining of adverse effects from dental materials, findings related to known general diseases or conditions and medications should be given particular consideration, while still in some patients, no objectifiable causes for their complaints can be found.
CLINICAL RELEVANCE
For patients complaining about adverse effects from dental materials, specialized consultations and close collaboration with experts from other medical fields are eligible.
Topics: Humans; Mouth Diseases; Dental Materials; Retrospective Studies; Xerostomia; Hypersensitivity
PubMed: 37212840
DOI: 10.1007/s00784-023-05064-5 -
American Journal of Dentistry Feb 2024To evaluate and compare the laboratory compressive strength (CS), flexural strength (FS), and diametral tensile strength (DTS) of Cention Forte and three bulk fill...
PURPOSE
To evaluate and compare the laboratory compressive strength (CS), flexural strength (FS), and diametral tensile strength (DTS) of Cention Forte and three bulk fill restorative materials.
METHODS
A total of 168 specimens were prepared following the manufacturers' instructions and standards for testing CS, FS, and DTS. Mechanical properties of Cention Forte (LC-Cent) were compared to three commercial bulk-fill materials for posterior restorations: Fuji IX Extra (Fuji), Tetric PowerFill (TPF), and Equia Forte HT (Equia). The tests were performed 24 hours after storage in distilled water on a universal testing machine at a crosshead speed of 0.75 mm/minute. Strength values (MPa) were calculated and statistically analyzed by one-way ANOVA and Tukey's post hoc test (P< 0.05).
RESULTS
Analysis showed significant differences between tested materials for CS, FS, and DTS (P= 0.0001). LC-Cent showed the highest mean value for FS (112.8 MPa) with a significant difference compared to Fuji and Equia. DTS (49.2 MPa) of LC-Cent was significantly higher than all tested materials. TPF showed the highest mean value (180 MPa) for CS but without significant difference compared to LC-Cent.
CLINICAL SIGNIFICANCE
Ion-releasing material Cention Forte, according to obtained results, may serve as a viable alternative for posterior restorations compared to conventional bulk-fill restorative materials.
Topics: Materials Testing; Dental Materials; Composite Resins
PubMed: 38458977
DOI: No ID Found -
Dental Materials : Official Publication... Apr 2024Although the introduction of self-adhesive composites in restorative dentistry is very promising, the innovation of new materials also presents challenges and unknowns....
OBJECTIVES
Although the introduction of self-adhesive composites in restorative dentistry is very promising, the innovation of new materials also presents challenges and unknowns. Therefore, the aim of this study was to investigate the cytotoxicity of four different self-adhesive composites (SAC) in vitro and to compare them with resin-modified glass ionomer cements (RM-GIC), a more established group of materials.
METHODS
Samples of the following materials were prepared according to ISO 7405/10993-12 and eluted in cell culture medium for 24 h at 37 °C: Vertise Flow, Fusio Liquid Dentin, Constic, Surefil One, Photac Fil and Fuji II LC. Primary human pulp cells were obtained from extracted wisdom teeth and cultured for 24 h with the extracts in serial dilutions. Cell viability was evaluated by MTT assay, membrane disruption was quantified by LDH assay and apoptosis was assessed by flow cytometry after annexin/PI staining.
RESULTS
Two SAC (Constic and Vertise Flow) and one RM-GIC (Photac Fil) significantly reduced cell viability by more than 30% compared to the untreated control (p < 0.001). Disruptive cell morphological changes were observed and the cells showed signs of late apoptosis and necrosis in flow cytometry. Membrane disruption was not observed with any of the investigated materials.
CONCLUSION
Toxic effects occurred independently of the substance group and need to be considered in the development of materials with regard to clinical implications.
CLINICAL SIGNIFICANCE
SAC have many beneficial qualities, however, the cytotoxic effects of certain products should be considered when applied in close proximity to the dental pulp, as is often required.
Topics: Humans; Resin Cements; Dental Cements; Composite Resins; Glass Ionomer Cements; Materials Testing; Dental Materials
PubMed: 38403539
DOI: 10.1016/j.dental.2024.02.015 -
Journal of Applied Clinical Medical... Aug 2023Radiotherapy with protons or light ions can offer accurate and precise treatment delivery. Accurate knowledge of the stopping power ratio (SPR) distribution of the...
Radiotherapy with protons or light ions can offer accurate and precise treatment delivery. Accurate knowledge of the stopping power ratio (SPR) distribution of the tissues in the patient is crucial for improving dose prediction in patients during planning. However, materials of uncertain stoichiometric composition such as dental implant and restoration materials can substantially impair particle therapy treatment planning due to related SPR prediction uncertainties. This study investigated the impact of using dual-energy computed tomography (DECT) imaging for characterizing and compensating for commonly used dental implant and restoration materials during particle therapy treatment planning. Radiological material parameters of ten common dental materials were determined using two different DECT techniques: sequential acquisition CT (SACT) and dual-layer spectral CT (DLCT). DECT-based direct SPR predictions of dental materials via spectral image data were compared to conventional single-energy CT (SECT)-based SPR predictions obtained via indirect CT-number-to-SPR conversion. DECT techniques were found overall to reduce uncertainty in SPR predictions in dental implant and restoration materials compared to SECT, although DECT methods showed limitations for materials containing elements of a high atomic number. To assess the influence on treatment planning, an anthropomorphic head phantom with a removable tooth containing lithium disilicate as a dental material was used. The results indicated that both DECT techniques predicted similar ranges for beams unobstructed by dental material in the head phantom. When ion beams passed through the lithium disilicate restoration, DLCT-based SPR predictions using a projection-based method showed better agreement with measured reference SPR values (range deviation: 0.2 mm) compared to SECT-based predictions. DECT-based SPR prediction may improve the management of certain non-tissue dental implant and restoration materials and subsequently increase dose prediction accuracy.
Topics: Humans; Dental Implants; Tomography, X-Ray Computed; Protons; Proton Therapy; Phantoms, Imaging
PubMed: 37032540
DOI: 10.1002/acm2.13977 -
The International Journal of... Feb 2024The aim of this scoping review is to categorize 3D-printing applications of polymeric materials into those where there is evidence to support their clinical application... (Review)
Review
PURPOSE
The aim of this scoping review is to categorize 3D-printing applications of polymeric materials into those where there is evidence to support their clinical application and to list the clinical applications that require a greater evidence base or further development before adoption.
MATERIALS AND METHODS
An electronic search on PubMed, EMBASE, Scopus (Elsevier), and Cochrane Library databases was conducted, including articles written in English and published between January 2003 and September 2023. The search terms were: ((3D printing) OR (3-dimensional printing) OR (three dimensional printing) OR (additive manufacturing)) AND ((polymer) OR (resin)) AND (dent*). Case reports, in vitro, in situ, ex vivo, or clinical trials focused on applications of 3D printing with polymers in dentistry were included. Review articles, systematic reviews, and articles comparing material properties without investigation on clinical application and performance/accuracy were excluded.
RESULTS
The search provided 3,070 titles, and 969 were duplicates and removed. A total of 2,101 records were screened during the screening phase, and 1,628 records were excluded based on title/abstract. In the eligibility phase, of the 473 full-text articles assessed for eligibility, 254 articles were excluded. During the inclusion phase, a total of 219 studies were included in qualitative synthesis.
CONCLUSIONS
There is lack of clinical evidence for the use of 3D-printing technologies in dentistry. Current evidence, when investigating clinical outcomes only, would indicate non-inferiority of 3D-printed polymeric materials for applications including diagnostic models, temporary prostheses, custom trays, and positioning/surgical guides/stents.
Topics: Printing, Three-Dimensional; Polymers; Humans; Dentistry; Dental Prosthesis Design; Dental Materials
PubMed: 38787586
DOI: 10.11607/ijp.8829 -
Journal of Esthetic and Restorative... Sep 2023Direct resin composite bonding offers a highly esthetic, minimally invasive option for the treatment of anterior teeth however the challenge to improve their longevity... (Review)
Review
STATEMENT OF PROBLEM
Direct resin composite bonding offers a highly esthetic, minimally invasive option for the treatment of anterior teeth however the challenge to improve their longevity remains. Direct resin composite restorations are limited by the risk of staining which may be influenced by the final surface roughness (Ra) of composite achieved.
PURPOSE
The purpose of this review is to investigate, using a systematic approach, whether the final surface roughness of anterior composite restorations is affected by the interaction between resin composite and polishing systems.
MATERIALS AND METHODS
The review was conducted by 3 independent reviewers and included articles published up to January 21, 2021. Three electronic databases were searched: Medline, Embase, and Web of Science. Studies assessing a quantitative effect of polishing methods on the Ra of direct composite resin materials published after the year 2000 and restricted to the English language were included.
RESULTS
The database search for the effect of polishing systems on composite materials retrieved 125 eligible studies. Twelve duplicate records were removed. The resulting records were screened using title and abstract leading to 38 reports which were sought for retrieval. Application of eligibility criteria led to 11 studies included in the review. Hand searching of these studies yielded no additional papers.
CONCLUSIONS
There is insufficient evidence to determine whether combination of composite and polisher influences final Ra. More research is required to determine if there is an optimum combination of polisher and composite.
CLINICAL IMPLICATIONS
Polishing should be completed following planned finishing procedures. The approximation to the final surface and which finishing burs to use, if any, should be considered when planning a restoration. Durafill VS predictably achieves an acceptable Ra by different polishers.
Topics: Dental Restoration, Permanent; Dental Polishing; Surface Properties; Diamond; Materials Testing; Dental Materials; Composite Resins
PubMed: 37458370
DOI: 10.1111/jerd.13102 -
BMC Oral Health Aug 2023Computer-aided design and computer-aided manufacturing (CAD-CAM) materials for prosthetic is gaining popularity in dentistry. However, limited information exists...
BACKGROUND
Computer-aided design and computer-aided manufacturing (CAD-CAM) materials for prosthetic is gaining popularity in dentistry. However, limited information exists regarding the impact of thickness and roughening treatment on the optical properties of contemporary CAD-CAM restorative materials. This study aimed to quantitatively evaluate the translucency and opalescence of six dental CAD-CAM materials in response to different thicknesses and roughening treatments.
METHODS
Six dental CAD-CAM materials, lithium disilicate glass-ceramic (IPS e.max CAD, LS), polymer-infiltrated ceramic (VITA Enamic, VE), resin-nano ceramic glass-ceramic (LAVA Ultimate, LU), polymethyl methacrylate (Telio CAD, TE), and two zirconia reinforced lithium silicate (VITA Suprinity, VS, and Celtra Duo, CD), in shade A2 were prepared as 12 × 12mm specimens of four thicknesses (0.5mm, 1.0mm, 1.5mm, and 2.0mm) (N = 240, n = 10). After three different treatments (polished, roughened by SiC P800-grit, and SiC P300-grit), the translucency parameter (TP) and opalescence parameter (OP) were measured with a spectrophotometer (VITA Easyshade V). The surface roughness was analyzed with a shape measurement laser microscope. The data were analyzed using a MANOVA, post hoc Tukey-Kramer test, the t test, and regression analysis (α = .05).
RESULTS
The TP and OP were significantly influenced by material type, thickness and roughening treatment (P < .05). TP showed a continues decline with increasing thicknesses, while the variations of OP were material-dependent. TP ranged from 37.80 (LS in 0.5mm) to 5.66 (VS in 2.0mm), and OP ranged from 5.66 (LU in 0.5mm) to 9.55 (VS in 0.5mm). The variations in TP of all materials between adjacent thicknesses ranged from 2.10 to 15.29, exceeding the acceptable translucency threshold except for LU. Quadratic and logarithmic regression curves exhibited the best fit for TP among the materials. Compared to polished specimens, rougher specimens exhibited lower TP00 and higher OP in all materials except for LS (P < 0.05). Roughening with P300-grit decreased TP and OP by an average of 2.59 and 0.43 for 0.5mm specimens, and 1.26 and 0.25 for 2.0mm specimens, respectively.
CONCLUSIONS
Variations in translucency caused by thickness and roughening treatment were perceptible and may be clinically unacceptable. Careful consideration should be given to the selection of CAD-CAM materials based on their distinct optical properties.
Topics: Humans; Iridescence; Research Design; Computer-Aided Design; Dental Materials; Microscopy, Confocal
PubMed: 37598167
DOI: 10.1186/s12903-023-03299-y -
The Journal of Prosthetic Dentistry Dec 2023Lithography-based additively manufactured (AM) zirconia has been used to fabricate dental implants and custom barriers for guided bone regeneration procedures. However,...
STATEMENT OF PROBLEM
Lithography-based additively manufactured (AM) zirconia has been used to fabricate dental implants and custom barriers for guided bone regeneration procedures. However, studies on the effect of AM zirconia on the biological properties of human osteoblasts are lacking.
PURPOSE
The purpose of this in vitro study was to compare the effect of milled and lithography-based AM zirconia on the biological properties of normal human osteoblasts (NHOsts), as well as to compare the chemical composition between the milled and lithography-based AM 3 mol% yttria-stabilized tetragonal zirconia polycrystal (3Y-TZP) zirconia.
MATERIAL AND METHODS
Three mol percentage yttria-stabilized tetragonal zirconia polycrystal disks (Ø6×2-mm) were fabricated using subtractive milling (Priti multidisc ZrO monochrome) (M group) and lithography-based additive manufacturing methods (LithaCon 3Y 210) (AM group) (n=10). NHOsts were exposed to different material extracts (1:1, 1:2, and 1:4) and cytotoxicity, cell migration, cell morphology, and cell attachment biological tests were completed. Additionally, for morphological and chemical analysis, a scanning electronic microscopy with energy-dispersive X-ray analysis (SEM/EDX) evaluation was completed. Data were analyzed by using 1-way ANOVA and the Dunnett test (α=.05).
RESULTS
Substantial cell attachment and spreading were observed in both material surfaces. The presence of zirconium was evident in both groups, although the percentage of zirconium in the AM group (64.7%) was slightly higher than in the M group (52.6%). When NHOsts were cultured in the presence of the different material eluates, the M and AM groups exhibited similar NHOst viability and migration rates when compared with untreated cells; no significant differences were found (P>.05).
CONCLUSIONS
The lithography-based AM zirconia tested showed adequate cytocompatibility without differences when compared with the milled zirconia (M group) specimens. Slight chemical element composition differences were found between milled and lithography-based AM zirconia.
Topics: Humans; Zirconium; Materials Testing; Yttrium; Osteoblasts; Surface Properties; Dental Materials; Ceramics
PubMed: 35264309
DOI: 10.1016/j.prosdent.2022.01.025 -
Journal of Esthetic and Restorative... May 2024Different materials and restorative concepts have been proposed over the years to restore endodontically treated teeth (ETT). Monolithic ceramic and composite...
INTRODUCTION
Different materials and restorative concepts have been proposed over the years to restore endodontically treated teeth (ETT). Monolithic ceramic and composite restoration can be lute to the tooh, without the use of a post. However, little is known how the material stiffness and presence of a composite core will affect the survival and failure mode. The objective of this in-vitro study was to evaluate the fracture strength and failure mode of endodontically treated molars, restored with ceramic or hybrid composite monolithic restoration, in the presence of absence of a composite core.
MATERIALS AND METHODS
Sixty depulped molars were restored with a lithium-disilicate (e.max CAD) or hybrid composite (Cerasmart) restoration. Both materials were used in a monolithic approach, but with 3 different designs: (a) monolithic endocrown, (b) crown with a separate composite core, and (c) overlay without core buildup or pulpal extension. Ten sound teeth were used as control group. All groups were thermocycled (10,000 cycles), subsequently loaded in a chewing simulator (100,000 cycles) and finally loaded until fracture.
RESULTS
Peak fracture loads and failure modes were registered. No significant differences were seen between the groups in terms of fracture load. Failure modes were statistically significantly different among groups with significant correlation between restoration type and material. (p < 0.001 and p = 0.033, respectively). No group presented significantly higher fracture resistance. Although ceramic crowns and overlays presented the highest repairability, all restored ETT were within the range of the intact tooth' fracture strength.
CONCLUSION
No restoration presented significant different fracture loads. However, the type of restoration and material choice were correlated to the fracture mode.
Topics: Humans; Flexural Strength; Tooth, Nonvital; Dental Restoration Failure; Dental Porcelain; Crowns; Ceramics; Tooth Fractures; Dental Stress Analysis; Materials Testing; Composite Resins
PubMed: 38152852
DOI: 10.1111/jerd.13187 -
ACS Applied Materials & Interfaces Sep 2023In orthodontic treatment, orthodontic appliances are prone to bacterial infections, which pose a risk to oral health. Surface modification of orthodontic appliances has...
In orthodontic treatment, orthodontic appliances are prone to bacterial infections, which pose a risk to oral health. Surface modification of orthodontic appliances has been explored to improve their antifouling properties and impart antibacterial capabilities, inhibiting initial bacterial adhesion and biofilm formation. However, coatings are susceptible to damage in the complex oral environment, leading to a loss of functionality. Here, we have prepared an antifouling self-healing coating based on supramolecular bonding by employing a simple spin coating method. The presence of the hydrophilic zwitterionic trimethylamine -oxide (TMAO) and the hydrophobic antimicrobial moieties triclosan acrylate (TCSA) imparts to the polymers an amphiphilic structure and enhances the interaction with bacteria, resulting in excellent antimicrobial activity and surface antifouling properties. The multiple hydrogen bonds of ureido-pyrimidinone methacrylate (UPyMA) and ionic interactions contained in the polymers not only increased the adhesion of the coating to the material substrate (approximately 3 times) but also endowed the coating with the intrinsic self-healing ability to restore the antibiofouling properties at oral temperature and humidity. Finally, the polymer coating is biologically safe both and , showing no cytotoxic effects on cells and tissues. This research offers a promising avenue for improving the performance of orthodontic appliances and contributes to the maintenance and treatment of oral health.
Topics: Biofouling; Anti-Bacterial Agents; Bacterial Adhesion; Cell Aggregation; Dental Materials
PubMed: 37623741
DOI: 10.1021/acsami.3c09628