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Materials (Basel, Switzerland) Feb 2024Knee osteoarthritis (OA) is one of the leading causes of disability around the globe. Osteoarthritis is mainly considered a disease affecting the elderly. However, more... (Review)
Review
Knee osteoarthritis (OA) is one of the leading causes of disability around the globe. Osteoarthritis is mainly considered a disease affecting the elderly. However, more and more studies show that sports overuse, obesity, or congenital disorders can initiate a pathologic cascade that leads to OA changes in the younger population. Nevertheless, OA mostly affects the elderly, and with increasing life expectancy, the disease will develop in more and more individuals. To date, the golden standard in the treatment of the end-stage of the disease is total joint replacement (TJR), which restores painless knee motion and function. One of the weakest elements in TJR is its bonding with the bone, which can be achieved by bonding material, such as poly methyl-methacrylate (PMMA), or by cementless fixation supported by bone ingrowth onto the endoprosthesis surface. Each technique has its advantages; however, the most important factor is the revision rate and survivor time. In the past, numerous articles were published regarding TJR revision rate, but no consensus has been established yet. In this review, we focused on a comparison of cemented and cementless total knee replacement surgeries. We introduced PICO rules, including population, intervention, comparison and outcomes of TJR in a PubMed search. We identified 783 articles published between 2010 and 2023, out of which we included 14 in our review. Our review reveals that there is no universally prescribed approach to fixate knee prostheses. The determination of the most suitable method necessitates an individualized decision-making process involving the active participation and informed consent of each patient.
PubMed: 38473607
DOI: 10.3390/ma17051136 -
Chemical Communications (Cambridge,... Nov 2023An optimized complex multi-component nanomaterial system would help greatly enhance the optical limiting performance and applicability of 2D nanomaterials. By using...
An optimized complex multi-component nanomaterial system would help greatly enhance the optical limiting performance and applicability of 2D nanomaterials. By using antimony sulfide-[-1-dodecyl-'-(α,α'-dimethyl-α''-acetic acid)trithiocarbonate] (SbS-DDAT) as a reversible addition fragmentation chain transfer (RAFT) agent, a highly soluble poly(-vinylcarbazole)-covalently modified SbS (SbS-PVK) was synthesized and embedded into a non-optically active poly(methylmethacrylate) (PMMA) matrix producing a PMMA-based film with good optical quality. In contrast to both the SbS/PMMA and SbS:PVK blends/PMMA films, the SbS-PVK/PMMA film exhibits more superior optical limiting performance. After annealing in N at 200 °C for 30 minutes, the achieved nonlinear absorption coefficient and limiting threshold are changed from 411.79 cm GW and 1.93 J cm at 532 nm and 242.79 cm GW and 4.17 J cm at 1064 nm before annealing to 478.04 cm GW and 1.70 J cm at 532 nm and 520.92 cm GW and 1.40 J cm at 1064 nm after annealing, respectively. These advantages make SbS-PVK one of the potential promising candidates for a broadband laser protector in both the visible and near-infrared ranges.
PubMed: 37850344
DOI: 10.1039/d3cc03712f -
The Journal of Contemporary Dental... Nov 2023This study aimed to assess the marginal and internal adaptation of provisional crowns fabricated from polymethyl methacrylate (PMMA) blocks by the computer-aided...
AIMS
This study aimed to assess the marginal and internal adaptation of provisional crowns fabricated from polymethyl methacrylate (PMMA) blocks by the computer-aided design/computer-aided manufacturing (CAD/CAM) system, autopolymerizing PMMA, and acrylic base composite resin.
MATERIALS AND METHODS
In this experimental study, a brass die was obtained, and provisional crowns were fabricated in three groups using Teliocad PMMA blocks by the CAD/CAM system, Tempron GC auto-polymerizing PMMA, and Bisico acrylic base composite resin ( = 7 in each group). The provisional crowns were coded and randomly placed on the die. Their marginal adaptation was evaluated under a stereomicroscope at 40× magnification, while their internal adaptation was assessed by the replica technique. Data were analyzed by one-way analysis of variance (ANOVA) (α = 0.05).
RESULTS
The mean marginal gap was the highest in autopolymerizing PMMA and the lowest in the CAD/CAM PMMA group ( < 0.05). The mean marginal gap in the autopolymerizing PMMA group was significantly higher than that in the resin material ( = 0.014) and CAD/CAM PMMA ( = 0.000) groups. The difference between the resin material and CAD/CAM PMMA groups was not significant ( = 0.13). The mean internal gap was the highest in autopolymerizing PMMA group and the lowest in CAD/CAM PMMA group ( < 0.05). The mean internal gap in autopolymerizing PMMA group was significantly higher than that in composite resin ( = 0.002) and CAD/CAM PMMA ( = 0.00) groups. The difference between the resin material and CAD/CAM PMMA groups was not significant ( = 0.322).
CONCLUSION
Computer-aided design/Computer-aided manufacturing PMMA provisional crowns showed the highest marginal and internal adaptation followed by acrylic base resin material crowns.
CLINICAL SIGNIFICANCE
Computer-aided design/computer-aided manufacturing PMMA crowns demonstrate superior marginal and internal adaptation compared with autopolymerizing PMMA and acrylic base composite resin crowns, suggesting CAD/CAM technology's potential for enhancing clinical outcomes. How to cite this article: Jalalian E, Younesi F, Golalipour S, Assessment of Marginal and Internal Adaptation in Provisional Crowns Utilizing Three Distinct Materials. J Contemp Dent Pract 2023;24(11):853-858.
Topics: Polymethyl Methacrylate; Dental Prosthesis Design; Crowns; Composite Resins; Acrylic Resins; Computer-Aided Design; Dental Marginal Adaptation; Materials Testing; Bisphenol A-Glycidyl Methacrylate
PubMed: 38238272
DOI: 10.5005/jp-journals-10024-3589 -
PeerJ 2023The study's objective is to assess the adherence of in different types of denture polymers and the effectiveness of eugenol and commercialized denture cleansers in the...
BACKGROUND
The study's objective is to assess the adherence of in different types of denture polymers and the effectiveness of eugenol and commercialized denture cleansers in the removal of . Three types of denture base polymers (Lucitone 199 (High-Impact PMMA), Impact (conventional PMMA) and Eclipse (UDMA)) and two hard denture reline materials (Kooliner and Tokuyama Rebase II Fast) were used in this study.
METHODS
Three hundred samples were prepared (6 × 2 mm disc shape) and divided into five groups of denture polymers ( = 60) and further subjected into five treatment groups (Polident, Steradent, distilled water, eugenol 5-minutes, and eugenol 10-min). Three samples were extracted from each treatment group for baseline data ( = 12). Baseline data were used to calculate the initial number of adherence. A 0.5 ml immersion solution from each specimen was cultured on YPD agar and incubated for 48 h at 37 °C. Visible colonies were counted using a colony counter machine (ROCKER Galaxy 230).
RESULTS
The result showed that the denture base polymer significantly affected the initial adherence ( = 0.007). The removal of was also considerably affected by the denture base polymers and denture cleansers ( < 0.05). Lucitone, Tokuyama, and Kooliner denture base polymers immersed for 3 min in eugenol showed the best results of removal.
DISCUSSION
This study's overall results showed that all denture polymers used as denture bases had an effect on initial adherence and removal from the denture base, and eugenol is comparable to commercialised denture cleansers in reducing the number of attached on denture base polymers.
Topics: Antifungal Agents; Candida albicans; Denture Cleansers; Eugenol; Polymethyl Methacrylate; Polymers; Dentures
PubMed: 37601266
DOI: 10.7717/peerj.15750 -
Head & Face Medicine Aug 2023The aim of this study was to establish a sheep model of the Puricelli biconvex arthroplasty (ABiP) technique in sheep for evaluating its functional, biological and...
BACKGROUND
The aim of this study was to establish a sheep model of the Puricelli biconvex arthroplasty (ABiP) technique in sheep for evaluating its functional, biological and histological parameters.
METHODS
Ten Corriedale black sheep were submitted to TMJ total reconstruction with poly(methyl methacrylate) (PMMA) using ABiP and euthanized after 45 (n = 5) or 90 (n = 5) days. Control animals (n = 2) underwent sham operations and were euthanized after 45 days. Variables were assessed before the surgery (T0), immediately after (T1) and at 45 or 90 postoperative days (T2).
RESULTS
Histological analyses showed regression of inflammatory cells over the follow-up period. PMMA showed reduced porosity and roughness in the articular contact area. PMMA temporal components showed linear and volumetric wear in comparison to control, but no foreign body reaction was observed. The reconstructions were stable in all animals. The amplitude of mouth opening and left lateral movements were maintained, except for a reduction in the range of right lateral movements at day 90 in the experimental group. Clinical, macroscopic and radiographic observations showed that the reconstructions were stable.
CONCLUSIONS
The analysis of functional, biological and histological parameters in sheep submitted to ABiP showed stable results of the procedure, with maintenance of body weight and all mandibular movements, save contralateral mandibular movement, suggesting that joint function was completely maintained following the procedure. This experimental study provides support for clinical results previously reported of the ABiP technique in TMJ reconstruction procedures.
Topics: Animals; Temporomandibular Joint Disorders; Polymethyl Methacrylate; Tooth Ankylosis; Arthroplasty; Mandible; Temporomandibular Joint; Range of Motion, Articular; Mandibular Condyle
PubMed: 37528466
DOI: 10.1186/s13005-023-00379-w -
The European Journal of Prosthodontics... Aug 2023The antimicrobial effect of prosthetic materials treated with chitosan was systematically reviewed.
OBJECTIVE
The antimicrobial effect of prosthetic materials treated with chitosan was systematically reviewed.
METHODS
The searches were carried out on PubMed/Medline, Scopus, ISI Web of Science, LILACS, Embase, and Open Grey with searches performed in March 2022. Selection of in vitro studies, data extraction and risk of bias analysis were performed following the PRISMA guidelines and registered at the Open Science Framework. The evaluated prosthetic materials corresponded to PMMA and tissue conditioner, treated with chitosan.
RESULTS
After evaluating the eligibility criteria, 11 articles were included for the qualitative synthesis. The evaluated prosthetic materials corresponded to PMMA (n=8) and tissue conditioner (n=3). All studies performed the incorporation of chitosan in the tissue conditioner (n=3). Regarding PMMA, the use of chitosan as a denture cleanser was the most used (n=3), followed by incorporation (n=2), multilayers coating onto PMMA (n=2) and denture adhesive for PMMA (n=1). Chitosan has antimicrobial activity and is effective in the treatment of prosthetic materials in most studies, but it depends on some factors, such as the treatment method, the type and characteristics of the chitosan, the microorganism evaluated, and its form of organization.
CONCLUSION
Chitosan showed highly antimicrobial activity and was effective when used in prosthetic materials.
Topics: Chitosan; Polymethyl Methacrylate; Anti-Infective Agents; Materials Testing
PubMed: 36515423
DOI: 10.1922/EJPRD_2454Muniz10 -
BMC Ophthalmology Mar 2024To measure the dislocation forces in relation to haptic material, flange size and needle used.
PURPOSE
To measure the dislocation forces in relation to haptic material, flange size and needle used.
SETTING
Hanusch Hospital, Vienna, Austria.
DESIGN
Laboratory Investigation.
METHODS, MAIN OUTCOME MEASURES
30 G (gauge) thin wall and 27 G standard needles were used for a 2 mm tangential scleral tunnel in combination with different PVDF (polyvinylidene fluoride) and PMMA (polymethylmethacrylate haptics). Flanges were created by heating 1 mm of the haptic end, non-forceps assisted in PVDF and forceps assisted in PMMA haptics. The dislocation force was measured in non-preserved cadaver sclera using a tensiometer device.
RESULTS
PVDF flanges achieved were of a mushroom-like shape and PMMA flanges were of a conic shape. For 30 G needle tunnels the dislocation forces for PVDF and PMMA haptic flanges were 1.58 ± 0.68 N (n = 10) and 0.70 ± 0.14 N (n = 9) (p = 0.003) respectively. For 27 G needle tunnels the dislocation forces for PVDF and PMMA haptic flanges were 0.31 ± 0.35 N (n = 3) and 0.0 N (n = 4), respectively. The flange size correlated with the occurring dislocation force in experiments with 30 G needle tunnels (r = 0.92), when flanges were bigger than 384 micrometres.
CONCLUSIONS
The highest dislocation forces were found for PVDF haptic flanges and their characteristic mushroom-like shape for 30 G thin wall needle scleral tunnels. Forceps assisted flange creation in PMMA haptics did not compensate the disadvantage of PMMA haptics with their characteristic conic shape flange.
Topics: Humans; Haptic Technology; Polymethyl Methacrylate; Sclera; Lenses, Intraocular; Fluorocarbon Polymers; Polyvinyls
PubMed: 38443841
DOI: 10.1186/s12886-024-03369-x -
PloS One 2023This study evaluated surface properties and adhesion/biofilm formation by Candida albicans on 3D printed denture base resins used in 3D printing. Disc-shaped specimens...
This study evaluated surface properties and adhesion/biofilm formation by Candida albicans on 3D printed denture base resins used in 3D printing. Disc-shaped specimens (15 mm x 3 mm) of two 3D-printed resins (NextDent Denture 3D+, NE, n = 64; and Cosmos Denture, CO, n = 64) and a heat-polymerized resin (Lucitone 550, LU, control, n = 64) were analyzed for surface roughness (Ra μm) and surface free energy (erg cm-2). Microbiologic assays (90-min adhesion and 48-h biofilm formation by C. albicans) were performed five times in triplicate, with the evaluation of the specimens' surface for: (i) colony forming units count (CFU/mL), (ii) cellular metabolism (XTT assay), and (iii) fluorescence and thickness of biofilm layers (confocal laser scanning microscopy). Data were analyzed using parametric and nonparametric tests (α = 0.05). LU presented higher surface roughness Ra (0.329±0.076 μm) than NE (0.295±0.056 μm) (p = 0.024), but both were similar to CO (0.315±0.058 μm) (p = 1.000 and p = 0.129, respectively). LU showed lower surface free energy (47.47±2.01 erg cm-2) than CO (49.61±1.88 erg cm-2) and NE (49.23±2.16 erg cm-2) (p<0.001 for both). The CO and NE resins showed greater cellular metabolism (p<0.001) and CO only, showed greater colonization (p = 0.015) by C. albicans than LU in the 90-min and 48-hour periods. It can be concluded that both 3D-printed denture base resins are more prone to colonization by C. albicans, and that their surface free energy may be more likely associated with that colonization than their surface roughness.
Topics: Candida albicans; Denture Bases; Biofilms; Surface Properties; Printing, Three-Dimensional; Materials Testing; Polymethyl Methacrylate
PubMed: 37792886
DOI: 10.1371/journal.pone.0292430 -
Medicina (Kaunas, Lithuania) Sep 2023Cranial defects pose significant challenges in low and middle-income countries (LIMCs), necessitating innovative and cost-effective craniofacial reconstruction... (Observational Study)
Observational Study
Cranial defects pose significant challenges in low and middle-income countries (LIMCs), necessitating innovative and cost-effective craniofacial reconstruction strategies. The purpose of this study was to present the Bosnia and Herzegovina model, showcasing the potential of a multidisciplinary team and 3D-based technologies, particularly PMMA implants, to address cranial defects in a resource-limited setting. An observational, non-experimental prospective investigation involved three cases of cranioplasty at the Department of Neurosurgery, Cantonal Hospital Zenica, Bosnia and Herzegovina, between 2019 and 2023. The technical process included 3D imaging and modeling with MIMICS software (version 10.01), 3D printing of the prototype, mold construction and intraoperative modification for precise implant fitting. The Bosnia and Herzegovina model demonstrated successful outcomes in cranioplasty, with PMMA implants proving cost-effective and efficient in addressing cranial defects. Intraoperative modification contributed to reduced costs and potential complications, while the multidisciplinary approach and 3D-based technologies facilitated accurate reconstruction. The Bosnia and Herzegovina model showcases a cost-effective and efficient approach for craniofacial reconstruction in LIMICs. Collaborative efforts, 3D-based technologies, and PMMA implants contribute to successful outcomes. Further research is needed to validate sustained benefits and enhance craniofacial reconstruction strategies in resource-constrained settings.
Topics: Humans; Bosnia and Herzegovina; Polymethyl Methacrylate; Developing Countries; Prospective Studies; Printing, Three-Dimensional
PubMed: 37893450
DOI: 10.3390/medicina59101732 -
Journal of Shoulder and Elbow Surgery Nov 2023Multiple techniques have been described to treat humeral diaphyseal bone tumors requiring curettage or excision. Recent studies have suggested that carbon...
BACKGROUND
Multiple techniques have been described to treat humeral diaphyseal bone tumors requiring curettage or excision. Recent studies have suggested that carbon fiber-reinforced polyetheretherketone (CFR-PEEK) intramedullary nails (IMNs) may be preferable to titanium IMNs for patients with musculoskeletal tumors due to CFR-PEEK's high tensile strength, radiolucency, a modulus of elasticity closer to native bone, and improved postoperative surveillance/radiation dosing. In this study, we describe the rate of fixation failure for both CFR-PEEK and titanium humeral IMNs when used for humeral diaphyseal bone tumors requiring curettage or excision.
METHODS
This was a single-institution retrospective cohort study including 81 patients (27 CFR-PEEK and 54 titanium) treated for a humeral diaphyseal bone tumor using an IMN ± methylmethacrylate between January 2017 and December 2022. Primary outcome was revision surgery due to soft tissue complications, nonunions, structural complications such as periprosthetic fracture or IMN breakage, periprosthetic infection, tumor progression, and implant failure due to rejection or fatigue.
RESULTS
No failures were observed in either patients treated with titanium nails or patients treated with CFR-PEEK not requiring curettage. Fixation failure due to implant failure was observed in 2 cases-at 214 days and 469 days after surgery-where CFR-PEEK IMN was used for stabilization after a wide segmental resection for oncologic control with a cement spacer reconstruction. In both cases, the resection was larger than 6 cm, the remaining distal humerus was less than 5 cm, and failures occurred at the interface of the residual bone and spacer. Both patients were revised using a titanium distal posterolateral humeral plate fixed with screws and cables without any subsequent complications. One additional CFR-PEEK IMN required revision surgery after 744 days due to progression of the tumor and subsequent nonunion. One revision surgery was observed after 63 days for the titanium IMN because of nonunion and tumor progression.
CONCLUSIONS
Humeral diaphyseal bone tumors requiring large segmental resection with small residual bone and a large cement spacer may fail via tension due to bending forces at the distal portion. In this clinical scenario, the use of larger-diameter CFR-PEEK IMNs may be indicated when available. In the interim, use of intercalary allografts instead of cement spacers, additional fixation with a titanium plate distally, or the use of a titanium nail when using a cement spacer may be considered.
Topics: Humans; Carbon Fiber; Titanium; Fracture Fixation, Intramedullary; Retrospective Studies; Treatment Outcome; Polyethylene Glycols; Ketones; Bone Neoplasms; Humerus; Bone Plates; Carbon; Humeral Fractures
PubMed: 37263478
DOI: 10.1016/j.jse.2023.04.023