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Scientific Reports Sep 2023Odor perception affects physiological and psychological states. Pupillary light reflex (PLR) parameters can be affected by olfactory stimulation and psychological...
Odor perception affects physiological and psychological states. Pupillary light reflex (PLR) parameters can be affected by olfactory stimulation and psychological states, although it remains unclear whether the olfactory stimulation-induced psychological changes can associate with PLR parameter changes. This study aimed to investigate effects of olfactory stimulation-induced psychological changes on PLR parameter changes with repeated measurements. We collected data on six mood subscales of the profile of mood states, and on five PLR parameter measurements from 28 healthy participants. Participants underwent a 10-min olfactory stimulation on different days with six odorants available with the T&T olfactometer. As obtained data were clustered, we used linear mixed-effects models for statistical analyses. The olfactory stimulation using the no-odor liquid did not affect mood states and the initial pupil size (INIT). The sweat odorant worsened all mood subscales including fatigue-inertia (Fatigue)/Vigor-Activity (Vigor), and decreased INIT compared to the no-odor liquid. When comparing INIT responses related to changes in mood subscales between the no-odor liquid and the sweat odorant, worsened states of Fatigue/Vigor were associated with decreased INIT in the sweat odorant. Fatigue/Vigor can be used as mental fatigue indicators. Thus, mental fatigue can be associated with decreased INIT in the olfactory stimulation.
Topics: Humans; Healthy Volunteers; Pupil; Smell; Odorants; Olfaction Disorders; Mental Fatigue
PubMed: 37749199
DOI: 10.1038/s41598-023-43004-1 -
Food Chemistry Oct 2023Kilned specialty malts provide relevant colour and flavour characteristics to beer and other beverages. Alongside the thermal load, the availability of Maillard...
Kilned specialty malts provide relevant colour and flavour characteristics to beer and other beverages. Alongside the thermal load, the availability of Maillard precursors directly affect the malt aroma formation. To investigate the influence of process parameters on the flavour characteristics of kilned specialty malts, a full factorial design of experiments was applied varying malt modification degree, curing temperature and time in three levels (3). Analysis of response surfaces revealed a predominant influence of the modification degree and curing temperature on the formation of Strecker aldehydes and pyrazines. Odorants such as 2-methylpropanal and 2-ethyl3,6-dimethylpyrazine presented higher concentrations varying between 429.45 and 478.22 µg∙K and 12.49 to 16.75 µg∙Kg respectively, at samples produced under 100 °C and high modification degree. Sensory analysis revealed strong correlations between the odorant markers and typical malt flavour attributes, endorsing the applicability of such methodology on the development and optimisation of kilned malt specialities.
Topics: Beer; Flavoring Agents; Odorants; Temperature
PubMed: 37229894
DOI: 10.1016/j.foodchem.2023.136298 -
Current Biology : CB Dec 2023Piriform cortex processes odor information coming from two nostrils to give rise to unified perception of odorant identity and intensity. A new study reveals that human...
Piriform cortex processes odor information coming from two nostrils to give rise to unified perception of odorant identity and intensity. A new study reveals that human piriform cortex harbours distinct representations of odor input from ipsilateral and contralateral nostrils through temporal segregation.
Topics: Humans; Olfactory Perception; Odorants; Piriform Cortex; Olfactory Pathways; Olfactory Cortex; Olfactory Bulb
PubMed: 38113838
DOI: 10.1016/j.cub.2023.11.023 -
BMC Public Health Jan 2024Many people suffer from body and breath malodour syndromes. One of these is trimethylaminuria, a condition characterized by excretion in breath and bodily fluids of...
BACKGROUND
Many people suffer from body and breath malodour syndromes. One of these is trimethylaminuria, a condition characterized by excretion in breath and bodily fluids of trimethylamine, a volatile and odorous chemical that has the smell of rotting fish. Trimethylaminuria can be primary, due to mutations in the gene encoding flavin-containing monooxygenase 3, or secondary, due to various causes. To gain a better understanding of problems faced by United Kingdom residents affected by body and breath malodour conditions, we conducted a survey.
METHODS
Two anonymous online surveys, one for adults and one for parents/guardians of affected children, were conducted using the Opinio platform. Participants were invited via a trimethylaminuria advisory website. Questions were a mix of dropdown, checkbox and open-ended responses. Forty-four adults and three parents/guardians participated. The dropdown and checkbox responses were analysed using the Opinio platform.
RESULTS
All participants reported symptoms of body/breath odour. However, not all answered every question. Twenty-three respondents experienced difficulties in being offered a diagnostic test for trimethylaminuria. Problems encountered included lack of awareness of the disorder by medical professionals and reluctance to recognise symptoms. Of those tested, 52% were diagnosed with trimethylaminuria. The main problems associated with living with body/breath malodours were bullying, harassment and ostracism in either the workplace (90%) or in social settings (88%). All respondents thought their condition had disadvantaged them in their daily lives. Open-ended responses included loss of confidence, stress, exclusion, isolation, loneliness, depression and suicidal thoughts. Respondents thought their lives could be improved by greater awareness and understanding of malodour conditions by medical professionals, employers and the general public, and appreciation that the malodour was due to a medical condition and not their fault.
CONCLUSIONS
Breath and body malodour conditions can cause immense hardship and distress, both mentally and socially, having devastating effects on quality of life. It would be advantageous to establish a standardised pathway from primary care to a specialist unit with access to a robust and reliable test and diagnostic criteria. There is a need to recognise malodour disorders as a disability, giving affected individuals the same rights as those with currently recognised disabilities.
Topics: Adult; Child; Animals; Humans; Quality of Life; Metabolism, Inborn Errors; Odorants; Anxiety; Methylamines
PubMed: 38238734
DOI: 10.1186/s12889-024-17685-w -
Scientific Reports Jul 2023Cat social behaviour and cognition has received a growing interest during the last decades. Recent studies reported that cats efficiently engage in interspecific...
Cat social behaviour and cognition has received a growing interest during the last decades. Recent studies reported that cats efficiently engage in interspecific communication with humans and suggest that cats are sensitive to human emotional visual and auditory cues. To date, there is no evidence on the social and informative role of human emotional odours, which may affect human-cat communication. In this study, we presented cats with human odours collected in different emotional contexts (fear, happiness, physical stress and neutral) and evaluated the animals' behavioural responses. We found that "fear" odours elicited higher stress levels than "physical stress" and "neutral", suggesting that cats perceived the valence of the information conveyed by "fear" olfactory signals and regulate their behaviour accordingly. Moreover, the prevalent use of the right nostril (right hemisphere activation) with the increase of stress levels, particularly in response to "fear" odours, provides first evidence of lateralized emotional functions of olfactory pathways in cats.
Topics: Humans; Cats; Animals; Odorants; Emotions; Smell; Happiness; Behavior, Animal
PubMed: 37414814
DOI: 10.1038/s41598-023-38167-w -
ACS Nano Nov 2023Deaf-blindness limits daily human activities, especially interactive modes of audio and visual perception. Although the developed standards have been verified as...
Deaf-blindness limits daily human activities, especially interactive modes of audio and visual perception. Although the developed standards have been verified as alternative communication methods, they are uncommon to the nondisabled due to the complicated learning process and inefficiency in terms of communicating distance and throughput. Therefore, the development of communication techniques employing innate sensory abilities including olfaction related to the cerebral limbic system processing emotions, memories, and recognition has been suggested for reducing the training level and increasing communication efficiency. Here, a skin-integrated and wireless olfactory interface system exploiting arrays of miniaturized odor generators (OGs) based on melting/solidifying odorous wax to release smell is introduced for establishing an advanced communication system between deaf-blind and non-deaf-blind. By optimizing the structure design of the OGs, each OG device is as small as 0.24 cm (length × width × height of 11 mm × 10 mm × 2.2 mm), enabling integration of up to 8 OGs on the epidermis between nose and lip for direct and rapid olfactory drive with a weight of only 24.56 g. By generating single or mixed odors, different linked messages could be delivered to a user within a short period in a wireless and programmable way. By adopting the olfactory interface message delivery system, the recognition rates for the messages have been improved 1.5 times that of the touch-based method, while the response times were immensely decreased 4 times. Thus, the presented wearable olfactory interface system exhibits great potential as an alternative message delivery method for the deaf-blind.
Topics: Humans; Odorants; Smell; Learning; Skin; Electronics
PubMed: 37917185
DOI: 10.1021/acsnano.3c08287 -
Physiology & Behavior Jan 2024Fewer and fewer people are reaching physical activity recommendations. Therefore, it seems important to make the practice of physical activity more enjoyable to increase... (Review)
Review
Fewer and fewer people are reaching physical activity recommendations. Therefore, it seems important to make the practice of physical activity more enjoyable to increase the participation rate. Several environmental factors have been studied to see their impact on sports practice, and some studies investigated the effect of odors. This systematic review aims to provide a thorough view of the literature on the effect of different odors on physical activity. The search strategy consisted of using index terms and keywords in MEDLINE, EMBASE, EBM Reviews - Cochrane Central Register of Controlled Trials, CINAHL, SPORTDiscus, and Web of Science search engine. Data from 19 studies that included 458 participants revealed that the odors had different results on strength, cardiovascular, precision, and postural balance tasks depending on the odors' exposition. Among results, an important distinction was made between pleasant and unpleasant odors. Therefore, pleasant odors had better results on physical activity by improving participants' feeling. Even though this review clarified evidence about the effect of odors on physical activity, better methodological consistency is needed across studies such as the odor administration method to produce more meaningful results.
Topics: Humans; Odorants; Exercise; Emotions; Sports; Postural Balance
PubMed: 37949307
DOI: 10.1016/j.physbeh.2023.114408 -
Food Chemistry Sep 2023The effect of micro-oxygenation (MOX) technique on quality and sensorial characteristics of balsamic vinegar was investigated, aiming to aging acceleration. Aging...
The effect of micro-oxygenation (MOX) technique on quality and sensorial characteristics of balsamic vinegar was investigated, aiming to aging acceleration. Aging experiments were conducted using a multiple diffuser micro-oxygenator for up to 6 months with an oxygen flow of 30 mg/L/month, including oak chips (1 g/L) or not. Barrel maturation was simultaneously carried out. Quality, nutritional, sensorial characteristics and the aromatic profile of all aged vinegars were evaluated throughout aging. MOX accelerated the alteration of aging indices. Volatile compounds of fruity aroma and wine were decreased, while the fatty/buttery and caramel aroma compounds were increased. Similar compounds of 1.5-year barrel maturation were developed within 6 and 5 months applying MOX without or with oak chips, respectively. MOX resulted in reduction of the aging time to 1/3 compared to the corresponding one in barrels, considered as an attractive approach for vinegar-producing industries, mimicking and accelerating the long and costly barrel aging.
Topics: Food Handling; Acetic Acid; Wine; Odorants
PubMed: 37011568
DOI: 10.1016/j.foodchem.2023.136077 -
Chemosphere Oct 2023Taste and odor (T&O) compounds present in natural water bodies could originate from algae. In this study, alga-generated compounds that can cause T&O issues in water,...
Taste and odor (T&O) compounds present in natural water bodies could originate from algae. In this study, alga-generated compounds that can cause T&O issues in water, such as geosmin (GE), 2-Methylisoborneol (MIB), 2,4,6-Trichloroanisole (TCA), 2-Methylbenzofuran (MB), 2-Isopropyl-3-methoxypyrazine (IPMP), 2-Isobutyl-3-methoxypyrazine (IBMP), cis-3-Hexenyl acetate (HA), trans,trans-2,4-Heptadienal (HD), trans,cis-2,6-Nonadienal (ND), and trans-2-Decenal (DN), were determined through solid-phase microextraction coupled with gas chromatography/mass spectrometry (HS-SPME GC/MS) and electronic tongue (E-tongue), and the results from the two techniques were compared. Although HS-SPME GC/MS facilitates the detection and quantification of T&O compounds with high precision and accuracy, the sample preparation and handling is difficult and the analysis time (1 h) is longer than those of other analytical methods. E-tongue can be used as an alternative analytical method for water quality analysis and risk management because it enables controlled and rapid analysis (3 min) of T&O compounds in water at a low cost. Notably, principal component analysis indicated that E-tongue can discriminate and quantify eight T&O compounds at as low as 0.02 μg L concentration. Further, partial least squares analysis confirmed that the sensor exhibits high sensitivity to concentration changes. The sensors with the highest variable importance in projection scores were determined to be SCS (1.39 and 1.38) for GE and MIB, CTS (1.34) for IPMP, CPS (1.33) for IBMP, AHS (1.42) for HA, ANS (1.22) for HD, and NMS (1.14 and 1.19) for ND and DN.
Topics: Odorants; Taste; Electronic Nose; Gas Chromatography-Mass Spectrometry
PubMed: 37478991
DOI: 10.1016/j.chemosphere.2023.139511 -
Insect Biochemistry and Molecular... Aug 2023Mosquitoes rely mainly on the sense of smell to decipher their environment and locate suitable food sources, hosts for blood feeding and oviposition sites. The molecular...
Mosquitoes rely mainly on the sense of smell to decipher their environment and locate suitable food sources, hosts for blood feeding and oviposition sites. The molecular bases of olfaction involve multigenic families of olfactory proteins that have evolved to interact with a narrow set of odorants that are critical for survival. Understanding the complex interplay between diversified repertoires of olfactory proteins and ecologically-relevant odorant signals, which elicit important behaviors, is fundamental for the design of novel control strategies targeting the sense of smell of disease vector mosquitoes. Previously, large multigene families of odorant receptor and ionotropic receptor proteins, as well as a subset of odorant-binding proteins have been shown to mediate the selectivity and sensitivity of the mosquito olfactory system. In this study, we identify a mosquito-specific antennal protein (MSAP) gene as a novel molecular actor of odorant reception. MSAP is highly conserved across mosquito species and is transcribed at an extremely high level in female antennae. In order to understand its role in the mosquito olfactory system, we generated knockout mutant lines in Anopheles gambiae, and performed comparative analysis of behavioral and physiological responses to human-associated odorants. We found that MSAP promotes female mosquito attraction to human odor and enhances the sensitivity of the antennae to a variety of odorants. These findings suggest that MSAP is an important component of the mosquito olfactory system, which until now has gone completely unnoticed.
Topics: Humans; Female; Animals; Odorants; Anopheles; Mosquito Vectors; Malaria; Receptors, Odorant; Smell
PubMed: 37437853
DOI: 10.1016/j.ibmb.2023.103988