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Indian Journal of Dermatology 2024Pityriasis Rosea (PR) is a common, yet enigmatic, dermatological condition characterized by a distinctive clinical presentation. Despite its prevalence, the aetiology...
BACKGROUND
Pityriasis Rosea (PR) is a common, yet enigmatic, dermatological condition characterized by a distinctive clinical presentation. Despite its prevalence, the aetiology and pathogenesis of PR remain elusive.
AIMS
To study the epidemiological and clinical aspects of patients with PR. To study dermoscopic findings and carry out histopathological correlation.
METHODS
A cross-sectional study of 50 patients was conducted. A detailed clinical history was taken and an examination was done followed by a dermoscopy. Quantitative data like age and duration of disease are presented with the help of standard deviation. Qualitative risk factors, like gender, age groups, symptomatology, site of lesion, findings or cutaneous examination, dermoscopy findings, and histopathology findings, are presented with the help of frequency and percentages.
RESULTS
PR shows male preponderance and mean age of occurrence being 30.8 ± 15.7 years. Forty per cent of patients had an atypical clinical presentation. The most frequently seen dermoscopy findings were diffuse red background (58%), peripheral collarette scale (62%), and peripheral dotted vessels (50%). On histopathology, the most common findings were spongiosis (44%), parakeratosis (38%), irregular acanthosis (34%), perivascular lymphocytic infiltrate (56%), and red blood cell extravasation (36%).
LIMITATIONS
Sample size was less due to COVID. As this was a corss-sectional study follow up of patients could not be done.
CONCLUSION
While the diagnosis of PR is clinical, it is difficult in atypical cases where dermoscopy comes to the aid. It also helps identify the age of lesions, thus helping decide the treatment strategy for patients. Biopsy remains the gold standard in ruling out other differentials of PR.
PubMed: 38841213
DOI: 10.4103/ijd.ijd_1071_23 -
The American Journal of Dermatopathology Jul 2024Spiny keratoderma is a rare entity presenting with minute keratotic spines on the palms and soles. Spiny keratoderma can be inherited or acquired, and the acquired form...
Spiny keratoderma is a rare entity presenting with minute keratotic spines on the palms and soles. Spiny keratoderma can be inherited or acquired, and the acquired form may be associated with underlying malignancy or systemic disease. Clinically, the differential diagnosis includes other digitate keratoses on acral sites, most notably arsenical keratosis, filiform verruca, and punctate porokeratosis. Biopsy findings typically include a column of parakeratosis overlying a diminished granular cell layer. In this article, we present 3 cases of acquired spiny keratoderma in patients with various systemic diseases, but no underlying malignancy.
Topics: Humans; Female; Male; Middle Aged; Keratoderma, Palmoplantar; Aged; Biopsy; Adult
PubMed: 38574081
DOI: 10.1097/DAD.0000000000002705 -
Annales de Dermatologie Et de... Jun 2024
Topics: Humans; Male; Diagnosis, Differential; Genital Diseases, Male; Parakeratosis; Penis; Psoriasis
PubMed: 38678769
DOI: 10.1016/j.annder.2024.103268