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Journal of Evidence-based Medicine Mar 2024Accumulating evidence has demonstrated that fractional flow reserves (FFRs) derived from invasive coronary angiograms (CA-FFRs) and coronary computed tomography... (Meta-Analysis)
Meta-Analysis
OBJECTIVE
Accumulating evidence has demonstrated that fractional flow reserves (FFRs) derived from invasive coronary angiograms (CA-FFRs) and coronary computed tomography angiography-derived FFRs (CT-FFRs) are promising alternatives to wire-based FFRs. However, it remains unclear which method has better diagnostic performance. This systematic review and meta-analysis aimed to compare the diagnostic performances of the two approaches.
METHODS
The Cochrane Library, PubMed, Embase, Medline (Ovid), the Chinese China National Knowledge Infrastructure Database (CNKI), VIP, and WanFang Data databases were searched for relevant studies that included comparisons between CA-FFR and CT-FFR, from their respective database inceptions until January 1, 2023. Studies where both noninvasive FFR (including CA-FFR and CT-FFR) and invasive FFR (as a reference standard) were performed for the diagnosis of ischemic coronary artery disease and were designed as prospective, paired diagnostic studies, were pulled. The diagnostic test accuracy method and Bayesian hierarchical summary receiver operating characteristic (ROC) model for network meta-analysis (NMA) of diagnostic tests (HSROC-NMADT) were both used to perform a meta-analysis on the data.
RESULTS
Twenty-six studies were included in this NMA. The results from both the diagnostic test accuracy and HSROC-NMADT methods revealed that the diagnostic accuracy of CA-FFR was higher than that of CT-FFR, in terms of sensitivity (Se; 0.86 vs. 0.84), specificity (Sp; 0.90 vs. 0.78), positive predictive value (PPV; 0.83 vs. 0.70), and negative predictive value (NPV; 0.91 vs. 0.89) for the detection of myocardial ischemia. A cumulative ranking curve analysis indicated that CA-FFR had a higher diagnostic accuracy than CT-FFR in the context of this study, with a higher area under the ROC curve (AUC; 0.94 vs. 0.87).
CONCLUSIONS
Although both of these two commonly used virtual FFR methods showed high levels of diagnostic accuracy, we demonstrated that CA-FFR had a better Se, Sp, PPV, NPV, and AUC than CT-FFR. However, this study provided only indirect comparisions; therefore, larger studies are warranted to directly compare the diagnostic performances of these two approaches.
Topics: Humans; Fractional Flow Reserve, Myocardial; Coronary Stenosis; Sensitivity and Specificity; Prospective Studies; Bayes Theorem; Network Meta-Analysis; Coronary Artery Disease; Coronary Angiography; Tomography, X-Ray Computed; Predictive Value of Tests
PubMed: 38205918
DOI: 10.1111/jebm.12573 -
Sports Biomechanics Dec 2023In this paper ways in which performance in 100 m front crawl might be improved are explored. Researchers were identified as 'primary sources' to provide a rationale for... (Review)
Review
In this paper ways in which performance in 100 m front crawl might be improved are explored. Researchers were identified as 'primary sources' to provide a rationale for how swimmers might improve their performance and to estimate the potential magnitude of improvement. The researchers selected as the primary sources were identified from an initial search of the Scopus and Web of Science data bases using keywords appropriate for the race phases including start, stroking, turn, and finish and their component sub-phases. Recent research was prioritised to ensure that the latest knowledge was considered. Based on an analogy drawn from the 'Chariots of Fire' movie, the hypothetical question was asked: how can we reduce the 100 m time by 0.5s of a swimmer who is already an elite performer? Estimates of potential improvement ranged from 0.013s for the reaction time in the start phase to 1.0s by optimising mid-pool kicking to minimise drag. It is concluded that even at the very elite level, fine-tuning to optimise performance in the different phases of the race could elevate an elite swimmer to podium level performance.
Topics: Humans; Swimming; Biomechanical Phenomena; Reaction Time; Bibliometrics
PubMed: 34766533
DOI: 10.1080/14763141.2021.1998590 -
Journal of Strength and Conditioning... Sep 2023Mäestu, J, Lelle, R, Mäestu, E, Pind, R, Vahtra, E, Purge, P, and Mikulic, P. Long-term rowing performance development in male Olympic and World Championship medal...
Mäestu, J, Lelle, R, Mäestu, E, Pind, R, Vahtra, E, Purge, P, and Mikulic, P. Long-term rowing performance development in male Olympic and World Championship medal winners compared with nonmedalists. J Strength Cond Res 37(9): e521-e526, 2023-The purpose of this study was, first, to investigate individual longitudinal 2,000 m rowing ergometer performance (2,000 erg) development of world class male rowers from the beginning of their career until reaching the elite level and to compare ELITE performance development with those who did not reach podium places and, second, to provide 2,000 erg milestones for talent prediction in rowing. Individual annual 2,000 erg performances of 54 male rowers were analyzed from age 15 and throughout their career. Olympic or World Championships medal winners (ELITE; n = 11) were compared with those who did not reach international podium places. Two thousand erg increased ( p ≤ 0.05) until the age of 24 in ELITE, while plateaued earlier for less successful rowers. No differences in the rate of performance improvement were found between ELITE and lower performers ( p > 0.05). At the age of 20, performance between ELITE and international level nonmedal winners reached significant difference (480.7 ± 20.9 W vs. 435.3 ± 33.9 W, respectively) and remained different onwards ( p ≤ 0.05). However, the average of the 10 best seasons cross-sectional performances of less successful rowers were significantly higher until age 18, compared with ELITE. ELITE rowers were able to improve their 2,000 erg performance to higher age; therefore, it is difficult to predict elite performers in junior rowers. Cross-sectional performances of less successful rowers may indicate temporary high-level performers, who might not be able to advance the elite level.
Topics: Humans; Male; Adolescent; Cross-Sectional Studies; Sports; Water Sports; Ergometry; Awards and Prizes
PubMed: 36728034
DOI: 10.1519/JSC.0000000000004479 -
Journal of Science and Medicine in Sport May 2024There is limited information on the performance progression of athletics endurance athletes from junior-to-senior status and the determinants of success in adulthood....
OBJECTIVES
There is limited information on the performance progression of athletics endurance athletes from junior-to-senior status and the determinants of success in adulthood. This study aimed to quantify the youth-to-senior transition rate, the likelihood of success and the relationship between youth and senior performance amongst world-class athletes competing in middle- and long-distance disciplines.
DESIGN
Retrospective design examining public data between 2000 and 2019.
METHODS
The performances of 4678 international athletes (45.3 % female) were analysed. World's all-time top 50 athletes were identified for U18 and Senior categories (age ≥ 20 years). Youth-to-senior transition rate and transition probabilities were calculated. Correlations between best U18 and Senior performances were determined to assess the stability of the performance.
RESULTS
The youth-to-senior transition rate for top U18 athletes was low for males and females (~19 % and 21 %). Nevertheless, the probability of transition to a top senior was ~7 times higher for top U18 athletes than for non-top U18 athletes. The correlations between youth and senior best performances were low-to-high.
CONCLUSIONS
Few top U18 athletes maintained top world ranking status during their senior careers. Still, they are more likely to become top senior athletes than those who did not perform at the top level in U18. The association between youth and senior performance is stronger when comparing the same discipline or when athletes competed over longer distances in their senior compared to U18 career. Being a successful youth athlete may represent a small advantage for future success, however, it does not guarantee advancement to the senior top level.
PubMed: 38821815
DOI: 10.1016/j.jsams.2024.05.007 -
Neurourology and Urodynamics Sep 2023Practice patterns around the use of urodynamic evaluation (UDS) for benign prostatic hyperplasia (BPH) surgery are largely undefined. As such, we investigated factors...
INTRODUCTION
Practice patterns around the use of urodynamic evaluation (UDS) for benign prostatic hyperplasia (BPH) surgery are largely undefined. As such, we investigated factors associated with the use of UDS for BPH.
METHODS
We used American Board of Urology case log data from 2008 to 2020, to compare patient- and surgeon-sided factors associated with UDS utilization and BPH surgeries. We performed logistic regression models to identify factors independently associated with UDS usage for BPH.
RESULTS
Among urologists performing UDS, the majority (80%) self-identified as general urologists and practiced in a private practice group (69%). Compared with urologists who performed no UDS, urologists who performed any UDS for BPH were more likely to be from the Mid-Atlantic (20.3% vs. 10.6%, p < 0.01) and practice in regions with populations of >1 000 000 (34.7% vs. 28.5%, p < 0.01). Overall, UDS utilization declined over time (odds ratio [OR]: 0.95 year-to-year, 95% confidence interval [CI]: 0.91-0.99). In adjusted analyses, the odds of performing UDS was higher among male (OR: 2.19, 95% CI: 1.17-4.09), older (OR: 1.05, 95% CI: 1.03-1.06), and female pelvic medicine and reconstructive surgery subspecialty (OR: 3.23, 95% CI: 2.01-5.2) urologists. Additionally, performing UDS for BPH was associated with higher BPH surgical case volume (OR: 1.004, 95% CI: 1.001-1.008).
CONCLUSION
There is a significant practice variation in use of UDS for BPH. Although overall BPH surgeries are increasing, urologists are increasingly less likely to perform UDS for BPH. Specifically, urologists who perform UDS have significantly higher BPH case volume than those who do not perform UDS, suggesting that UDS usage may not factor into BPH surgery decision-making.
Topics: Humans; Male; Female; Prostatic Hyperplasia; Urodynamics; Practice Patterns, Physicians'; Urology; Urologists
PubMed: 37395472
DOI: 10.1002/nau.25239 -
Frontiers in Psychology 2023When sight-reading a score, a timpanist needs to decide in real-time which stick to use to play a specific note while interpreting the musical material. Our main point...
When sight-reading a score, a timpanist needs to decide in real-time which stick to use to play a specific note while interpreting the musical material. Our main point of inquiry seeks to understand which sticking patterns performers employ and how they are affected by rhythmic stability. This paper analyzes the bi-manual sequencing (i.e., sticking) patterns of 31 timpanists in a sight-reading task. We analyze their results compared to model sticking patterns common in percussion pedagogical literature. Results show that while hand dominance plays an essential role in an individual's sticking pattern, the stability of a rhythmic pattern may also dramatically influence the observed particular sticking strategies. In areas of rhythmic stability, performers largely adhered to one of two conventional sticking patterns in the literature (dominant hand lead & alternating). Where rhythmic patterns became more unstable, the performers separated into diverse sticking groups. Moreover, several performers demonstrated sticking patterns which were hybrids or an inverse of the model sticking patterns, without any impact on the success of their sight-reading abilities. Overall, no two individual performers demonstrated the same sticking pattern. In terms of percussion pedagogy, our findings suggest that performers may benefit from an awareness of the adaptability of model sticking strategies. Lastly, we make the case for further study of rhythmic stability and bi-manual sequencing by locating the difference between notational and aural complexity.
PubMed: 37780147
DOI: 10.3389/fpsyg.2023.1188773 -
Sports Medicine (Auckland, N.Z.) Mar 2024Does younger involvement in talent promotion programs (TPPs) facilitate the attainment of higher performance levels? This question is the subject of the present... (Meta-Analysis)
Meta-Analysis
BACKGROUND
Does younger involvement in talent promotion programs (TPPs) facilitate the attainment of higher performance levels? This question is the subject of the present meta-analysis. Many national sport systems have established TPPs such as federations' junior squads (including under-age selection teams) and youth sport academies, and many are making expanding investments in TPPs. TPPs seek to select the most advanced youth high performers at young ages, around puberty or younger, and then strive to further accelerate their performance development. However, studies show 25-55% annual athlete turnover within TPPs. In this context, accelerated biological maturation (puberty, growth spurt), high relative age within one's birth year, and intensified sport-specific childhood/adolescent practice may boost rapid junior performance, but the effects diminish or are reversed by adulthood. Moreover, expanded opportunity costs and risks (time demands, injury, burnout) imposed on young TPP participants may impair their long-term development and even prematurely terminate their career.
OBJECTIVE
We aimed to provide robust and generalizable evidence on the effects of early talent promotion on junior and senior performance through a systematic review and meta-analysis.
METHODS
A systematic literature search was conducted 18/03-03/04/2023 in SPORTDiscus, ProQuest, PsycINFO, PubMed, Scopus, WorldCat, and Google Scholar. We searched for original studies that compared athletes across defined higher and lower performance levels within defined types of sports, age categories, and sexes, regarding their age at commencement of TPP involvement and reported effect sizes or data needed to compute effects sizes. Mean meta-analytic Cohen's was computed separately for junior and senior athletes. Quality of evidence was evaluated using the mixed-methods appraisal tool.
RESULTS
The search yielded k = 51 effect sizes from N = 6233 athletes from a wide range of countries and sports, 82% male and 18% female, from 2009 to 2022. The central finding is that effects on short-term junior performance versus long-term senior performance are opposite, whereby higher-performing junior athletes began TPP involvement at younger ages than lower-performing junior athletes, = - 0.53. In contrast, higher-performing senior athletes began TPP involvement at older ages than lower-performing senior athletes, = 0.56. The findings are robust across different TPPs (federation's junior squad/selection team, youth academy), individual and team sports, and performance levels compared (international, national, regional). The quality of primary studies was high.
DISCUSSION
The findings are consistent with recent meta-analytic evidence that participation patterns predicting early junior success versus long-term senior success are opposite (starting age, main-sport and other-sports practice amounts, age to reach performance 'milestones'). We discuss theoretical and practical implications of potential selection and 'treatment' effects of TPPs.
CONCLUSIONS
Consistent across different populations, early TPP involvement is positively correlated with short-term junior performance but is negatively correlated with long-term senior performance.
Topics: Adolescent; Humans; Male; Female; Adult; Child; Sports; Athletes; Team Sports; Aptitude; Youth Sports
PubMed: 37921913
DOI: 10.1007/s40279-023-01957-3 -
PeerJ 2024The performance of balance is an important factor to perform activities. The complications of type 2 diabetes mellitus (T2DM), especially vestibular dysfunction (VD),...
BACKGROUND
The performance of balance is an important factor to perform activities. The complications of type 2 diabetes mellitus (T2DM), especially vestibular dysfunction (VD), could decrease balance performance and falls-efficacy (FE) which consequently impacts social participation and quality of life (QoL).
PURPOSE
This study aimed to compare balance performance, FE, social participation and QoL between individuals with T2DM with and without VD.
METHODS
The participants comprised 161 T2DM with VD and 161 without VD. Three clinical tests used for confirming VD included the Head Impulse Test (HIT), the Dix Hallpike Test (DHT) and the Supine Roll Test (SRT). The scores of static and dynamic balances, FE, social participation and QoL were compared between groups.
RESULTS
The balance performance, FE, social participation and QoL were lower in the group with VD. The number of patients who had severe social restriction was higher in T2DM with VD than without VD (58.4% 48.4%). Moreover, all domains of QoL (physical, psychological, social relationships and environmental) were lower in T2DM with VD than without VD.
CONCLUSION
The presence of VD in T2DM patients was associated with decreased physical balance performances and increased social and QoL disengagement. Comprehensive management related to balance and FE, as well as the monitoring to support social participation and QoL, should be emphasized in patients with T2DM with VD.
Topics: Humans; Diabetes Mellitus, Type 2; Postural Balance; Male; Female; Quality of Life; Accidental Falls; Middle Aged; Vestibular Diseases; Social Participation; Aged
PubMed: 38766481
DOI: 10.7717/peerj.17287 -
Ergonomics May 2024Firefighters routinely perform tasks that are reliant on their muscular fitness, which includes muscular strength, power and endurance. Separately, firefighters can... (Review)
Review
Firefighters routinely perform tasks that are reliant on their muscular fitness, which includes muscular strength, power and endurance. Separately, firefighters can present with unique skeletal muscle physiology characteristics due to the strenuous nature of this occupation. This review aims to summarise muscular fitness and physiology as determinants of a firefighter's ability to perform occupation-specific tasks, identify the relevance of both muscular fitness and physiology to a firefighter's risk for sustaining a work-related injury, and address the contributions of muscular fitness and physiology on a firefighter's ability to recover from tasks and their readiness for performing subsequent or future tasks. The presented evidence reveals muscular fitness can determine a firefighter's capacity to perform their job effectively, while also influencing risk for occupational injury. Collectively, this review indicates exercise training emphasising improvements in muscular strength, power, and endurance (i.e. resistance training) should be encouraged in this occupation.
PubMed: 38742476
DOI: 10.1080/00140139.2024.2352719 -
IEEE Transactions on Pattern Analysis... Mar 2024Multi-Source Domain Adaptation (MSDA) focuses on transferring the knowledge from multiple source domains to the target domain, which is a more practical and challenging...
Multi-Source Domain Adaptation (MSDA) focuses on transferring the knowledge from multiple source domains to the target domain, which is a more practical and challenging problem compared to the conventional single-source domain adaptation. In this problem, it is essential to model multiple source domains and target domain jointly, and an effective domain combination scheme is also highly required. The graphical structure among different domains is useful to tackle these challenges, in which the interdependency among various instances/categories can be effectively modeled. In this work, we propose two types of graphical models, i.e. Conditional Random Field for MSDA (CRF-MSDA) and Markov Random Field for MSDA (MRF-MSDA), for cross-domain joint modeling and learnable domain combination. In a nutshell, given an observation set composed of a query sample and the semantic prototypes (i.e. representative category embeddings) on various domains, the CRF-MSDA model seeks to learn the joint distribution of labels conditioned on the observations. We attain this goal by constructing a relational graph over all observations and conducting local message passing on it. By comparison, MRF-MSDA aims to model the joint distribution of observations over different Markov networks via an energy-based formulation, and it can naturally perform label prediction by summing the joint likelihoods over several specific networks. Compared to the CRF-MSDA counterpart, the MRF-MSDA model is more expressive and possesses lower computational cost. We evaluate these two models on four standard benchmark data sets of MSDA with distinct domain shift and data complexity, and both models achieve superior performance over existing methods on all benchmarks. In addition, the analytical studies illustrate the effect of different model components and provide insights about how the cross-domain joint modeling performs.
PubMed: 35503821
DOI: 10.1109/TPAMI.2022.3172372