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Journal of Adolescent and Young Adult... Dec 2023The appreciation of peer support can vary from one country to another due to the cultural and relational differences. This study explores what perceptions French...
The appreciation of peer support can vary from one country to another due to the cultural and relational differences. This study explores what perceptions French adolescents and young adults (AYAs) in post-treatment for cancer have of the place of sick peers during their treatment and what can make barriers to meet them. A semistructured interview has been proposed 6 months after the end of cancer treatments. A thematic analysis has been conducted to highlight the major themes and subthemes identified through the participants' discourses. Twelve AYAs (mean age 23 y.o., standard deviation = 2.8; min = 19; max = 26) from two French cancer centers were interviewed. Five major themes were identified, but only two were presented in this article: the place of peers and the impact of coronavirus disease 2019 (COVID-19) epidemic on AYA facilities. AYA peers with cancer major theme demonstrated that meeting sick peers has benefits (e.g., identification, understanding, support, feeling of normalcy) but also has disadvantages (e.g., negative emotional influence). The benefits of peer-to-peer meetings seem to outweigh the disadvantages. Nevertheless, AYAs can face social barriers to this kind of relationship (e.g., fatigue, need to focus on oneself, confrontation to cancer and negative events, feeling of unnatural meeting). Finally, patients' encounters and the normal functioning of AYA facilities have been hampered by the COVID-19 pandemic. Even if AYA services systematically suggest a meeting with other sick peers, it is important to reiterate this proposal since the needs can evolve over time. It can also be interesting to propose places of life outside the hospital to make the encounters more comfortable and natural for AYAs. Clinical Trial Registration number: NCT03964116.
Topics: Humans; Adolescent; Young Adult; Adult; Pandemics; Neoplasms; Peer Group; Emotions
PubMed: 36999900
DOI: 10.1089/jayao.2022.0176 -
Current Opinion in Infectious Diseases Aug 2024This review covers recent research regarding the challenges posed by climate change within the areas of antimicrobial stewardship and infection prevention, and ways to... (Review)
Review
PURPOSE OF REVIEW
This review covers recent research regarding the challenges posed by climate change within the areas of antimicrobial stewardship and infection prevention, and ways to build resiliency in these fields.
RECENT FINDINGS
Infectious disease patterns are changing as microbes adapt to climate change and changing environmental factors. Capacity for testing and treating infectious diseases is challenged by newly emerging diseases, which exacerbate challenges to antimicrobial stewardship and infection prevention.Antimicrobial resistance is accelerated due to environmental factors including air pollution, plastic pollution, and chemicals used in food systems, which are all impacted by climate change.Climate change places infection prevention practices at risk in many ways including from major weather events, increased risk of epidemics, and societal disruptions causing conditions that can overwhelm health systems. Researchers are building resilience by advancing rapid diagnostics and disease modeling, and identifying highly reliable versus low efficiency interventions.
SUMMARY
Climate change and associated major weather and socioeconomic events will place significant strain on healthcare facilities. Work being done to advance rapid diagnostics, build supply chain resilience, improve predictive disease modeling and surveillance, and identify high reliability versus low yield interventions will help build resiliency in antimicrobial stewardship and infection prevention for escalating challenges due to climate change.
Topics: Climate Change; Humans; Antimicrobial Stewardship; Communicable Diseases
PubMed: 38843434
DOI: 10.1097/QCO.0000000000001032 -
Integrative Psychological & Behavioral... Mar 2024In this article, the authors argue for a decolonial history of psychology that will assist in the creation of psychologies (and their histories) that are true to place...
In this article, the authors argue for a decolonial history of psychology that will assist in the creation of psychologies (and their histories) that are true to place and time. We briefly place contemporary history of psychology as being of service to hegemonic psychology, which has continued to enforce a coloniality of being, knowing, and doing. We outline some of its limitations in regard to individualism, neoliberalism, and the ideologies of the market. In contrast, we articulate a way to begin to reconceptualize a psychology and its history that may serve to honor and respect multiple ways of knowing and being. We offer examples of emergent approaches that are being created that are non-dualistic, non-WEIRD, and focused on lived experiences in particular places and settings. The authors are mindful of the limitations of offering superabundant examples of each point due to the length constraints that accompanied the invitation to submit this manuscript. We encourage interested readers to explore the references for additional nuances and examples of the main points.
Topics: Humans; Colonialism; Psychology, Social
PubMed: 37291446
DOI: 10.1007/s12124-023-09779-8 -
The Science of the Total Environment Mar 2024Tropical oceans are among the first places to exhibit climate change signals, affecting the habitat distribution and abundance of marine fish. These changes to stocks,... (Meta-Analysis)
Meta-Analysis
Tropical oceans are among the first places to exhibit climate change signals, affecting the habitat distribution and abundance of marine fish. These changes to stocks, and subsequent impacts on fisheries production, may have considerable implications for coastal communities dependent on fisheries for food security and livelihoods. Understanding the impacts of climate change on tropical marine fisheries is therefore an important step towards developing sustainable, climate-ready fisheries management measures. We apply an established method of spatial meta-analysis to assess species distribution modelling datasets for key species targeted by the Philippines capture fisheries. We analysed datasets under two global emissions scenarios (RCP4.5 and RCP8.5) and varying degrees of fishing pressure to quantify potential climate vulnerability of the target community. We found widespread responses to climate change in pelagic species in particular, with abundances projected to decline across much of the case study area, highlighting the challenges of maintaining food security in the face of a rapidly changing climate. We argue that sustainable fisheries management in the Philippines in the face of climate change can only be achieved through management strategies that allow for the mitigation of, and adaptation to, pressures already locked into the climate system for the near term. Our analysis may support this, providing fisheries managers with the means to identify potential climate change hotspots, bright spots and refugia, thereby supporting the development of climate-ready management plans.
Topics: Animals; Fisheries; Ecosystem; Oceans and Seas; Climate Change; Hunting; Fishes
PubMed: 38320704
DOI: 10.1016/j.scitotenv.2024.170684 -
Journal of the World Federation of... Feb 2024Temporary skeletal anchorage devices such as miniscrews are frequently used nowadays. Compared to miniplates, miniscrews are much less expensive and technically easier...
Temporary skeletal anchorage devices such as miniscrews are frequently used nowadays. Compared to miniplates, miniscrews are much less expensive and technically easier to place and remove; they are popular and can be easily placed by an orthodontist. Extra-alveolar miniscrews offer benefits compared to inter-radicular miniscrews, such as reduced risk of root damage and the lack of interference with the mesiodistal tooth movement. They are particularly useful for addressing anchorage loss issues and enabling specific tooth movements such as total arch maxillary and mandibular retraction, posterior distalization, molar protraction, molar intrusion, occlusal plane control, and midline correction. The present paper discusses the current biomechanics principles related to the use of extra-alveolar miniscrews placed in the infrazygomatic and mandibular buccal shelf.
Topics: Biomechanical Phenomena; Bone Screws; Orthodontic Anchorage Procedures; Tooth Movement Techniques; Mandible
PubMed: 38155064
DOI: 10.1016/j.ejwf.2023.12.002 -
The Gerontologist Feb 2024This paper argues for a greater theorization of "place" within aging-in-place research. It extends calls for a relational conceptualization of place by demonstrating the...
This paper argues for a greater theorization of "place" within aging-in-place research. It extends calls for a relational conceptualization of place by demonstrating the need for aging-in-place researchers to also pay greater attention to territorial aspects of place. This complementary understanding will help establish a new spatial grammar within aging-in-place research, that not only would improve conceptual clarity to aging in place, but would also support a more critical engagement of aging in place in questions of inequality. The paper demonstrates this through a discussion of 2 forms of inequality pertinent to older people: the uneven capacity of places to support older people and experiences of social exclusion in relation to place attachment for older people from marginalized groups.
Topics: Humans; Aged; Independent Living; Aging
PubMed: 36655690
DOI: 10.1093/geront/gnad002 -
Frontiers in Psychology 2024In contemporary society, people spend long periods under high stress, and tourism activities have gradually been internalized as a new means of stress release and...
INTRODUCTION
In contemporary society, people spend long periods under high stress, and tourism activities have gradually been internalized as a new means of stress release and self-recovery. Studies have found that the high-quality natural environment of rural tourism destinations has a higher restorative effect than other places, and the rural natural environment can provide psychological recovery to visitors on top of offering visual beauty and other experiences.
METHODS
This paper starts with the relationship between rural place perception and restorative experience evaluation. Based on theories such as the restorative environments theory, we investigates whether rural natural environmental factors have a restorative effect on recreationists through collecting 300 questionnaires and using SPSS 26.0 structural equation modeling for analysis.
RESULTS
The study found that there is a positive correlation between rural natural perception, place dependence, and restorative experience, forming a positive feedback loop dynamic system. The analysis suggests that enhancing the perception of the rural natural environment and place attachment can improve the restorative experience of recreationists in rural settings.
DISCUSSION
This research establishes a systematic research framework for the relationship between rural natural perception, place attachment, and restorative experience, to deeply understand the dynamic interaction between them. It reveals the relationship between rural natural perception and restorative experience, suggesting that enriching the perceptual elements in rural natural spaces can meet the diverse needs of recreationists, enhance the sense of dependence and identification with rural spaces, and thus promote the psychological well-being and restorative experience of recreationists. The study also finds that place dependence plays a mediating role between rural natural perception and restorative experience. Place attachment and place identity, as mediating variables, act as bridges and catalysts in the process of rural natural perception affecting restorative experience.
PubMed: 38845763
DOI: 10.3389/fpsyg.2024.1341956 -
Nursing Open Aug 2023HIV remains a statistically significant issue for women of childbearing age in Ghana. Nurses and midwives form the backbone of care providers for the prevention of...
UNLABELLED
HIV remains a statistically significant issue for women of childbearing age in Ghana. Nurses and midwives form the backbone of care providers for the prevention of mother-to-child transmission programmes. However, nurses and midwives receive little support to provide the emotional aspects of HIV/AIDS care.
AIM
Our aim was to build an understanding of how midwives currently embrace their experience of hope and hoping to support mothers living with HIV.
DESIGN
This is narrative inquiry study.
METHODS
We engaged in two to three conversations with five midwives in rural settings in Ghana to understand their experiences of hope and hoping in their interactions with mothers living with HIV. Using the narrative inquiry common places of temporality, the social and personal, and space/place, we wrote narrative accounts for each participant and then searched for resonances across the narrative accounts.
RESULTS
We highlight three emerging narrative threads that resonated across narrative accounts. The three emerging narrative threads were (1) sustaining hope by drawing on life experiences across time and place; (2) hope is sustained through a focus on relational engagement with mothers; (3) midwives embrace the possibility to learn more about hope-focused practices.
CONCLUSION
The midwives began, although tentatively, to shine light on the things and events that diminished their abilities to maintain a hopeful perspective. At the same time, they became more comfortable and familiar with the notion of making hope visible and accessible in their experiences.
IMPACT
Since the midwives welcomed additional support to cope with the challenges they were experiencing, we imagine one day being able to make sense of how nurses and midwives engage with a narrative pedagogy of hope. Including hope-focused practices in nursing and midwifery preservice and in-service opportunities is important.
PATIENT OR PUBLIC CONTRIBUTION
There was no direct patient or public involvement in this study.
Topics: Pregnancy; Female; Humans; Midwifery; Ghana; Qualitative Research; Infectious Disease Transmission, Vertical; HIV Infections
PubMed: 37101353
DOI: 10.1002/nop2.1787 -
Frontiers in Molecular Biosciences 2023After the COVID-19 pandemic, messenger RNA (mRNA) has revolutionized traditional vaccine manufacturing. With the increasing number of RNA-based therapeutics, valuable...
After the COVID-19 pandemic, messenger RNA (mRNA) has revolutionized traditional vaccine manufacturing. With the increasing number of RNA-based therapeutics, valuable new scientific insights into these molecules have emerged. One fascinating area of study is the formation of double-stranded RNA (dsRNA) during transcription (IVT) which is considered a significant impurity, as it has been identified as a major trigger in the cellular immune response pathway. Therefore, there is a growing importance placed to develop and optimize purification processes for the removal of this by-product. Traditionally, efforts have primarily focused on mRNA purification after IVT through chromatographic separations, with anion exchange and reverse phase chromatography emerging as effective tools for this purpose. However, to the best of our knowledge, the influence and significance of the quality of the linearized plasmid have not been thoroughly investigated. Plasmids production involves the growth of bacterial cultures, bacterial harvesting and lysis, and multiple filtration steps for plasmid DNA purification. The inherent complexity of these molecules, along with the multitude of purification steps involved in their processing, including the subsequent linearization and the less-developed purification techniques for linearized plasmids, often result in inconsistent batches with limited control over by-products such as dsRNA. This study aims to demonstrate how the purification process employed for linearized plasmids can impact the formation of dsRNA. Several techniques for the purification of linearized plasmids based on both, resin filtration and chromatographic separations, have been studied. As a result of that, we have optimized a chromatographic method for purifying linearized plasmids using monolithic columns with C4 chemistry (butyl chains located in the surface of the particles), which has proven successful for mRNAs of various sizes. This chromatographic separation facilitates the generation of homogeneous linearized plasmids, leading to mRNA batches with lower levels of dsRNA during subsequent IVT processes. This finding reveals that dsRNA formation is influenced not only by RNA polymerase and IVT conditions but also by the quality of the linearized template. The results suggest that plasmid impurities may contribute to the production of dsRNA by providing additional templates that can be transcribed into sequences that anneal with the mRNA molecules. This highlights the importance of considering the quality of plasmid purification in relation to dsRNA generation during transcription. Further investigation is needed to fully understand the mechanisms and implications of plasmid-derived dsRNA. This discovery could shift the focus in mRNA vaccine production, placing more emphasis on the purification of linearized plasmids and potentially saving, in some instances, a purification step for mRNA following IVT.
PubMed: 37842641
DOI: 10.3389/fmolb.2023.1248511 -
Nederlands Tijdschrift Voor Geneeskunde Oct 2023Older patients who experience a fall may be admitted to hospital without a strict medical necessity. An unexplained fall incident requires thorough history taking and,...
Older patients who experience a fall may be admitted to hospital without a strict medical necessity. An unexplained fall incident requires thorough history taking and, if necessary, further investigation into the cause of the fall. Possible underlying multimorbidity must also be examined to prevent recurrence and complications. Admission to hospital without medical necessity is undesirable, but often unavoidable due to a lack of alternatives for patients who can no longer care for themselves in an acute situation. Reducing this unnecessary health care consumption is only possible if the options for care outside the hospital are expanded. In addition to regional cooperation to gain insight into available home care and places to stay, the use of unlabeled beds in care homes for further assessment of care needs and triage could help resolve this issue. In this way we can work together to provide the right care in the right place.
Topics: Humans; Hospitalization; Triage; Home Care Services
PubMed: 37850619
DOI: No ID Found