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Physics of Life Reviews Sep 2023Sociality and timing are tightly interrelated in human interaction as seen in turn-taking or synchronised dance movements. Sociality and timing also show in... (Review)
Review
Sociality and timing are tightly interrelated in human interaction as seen in turn-taking or synchronised dance movements. Sociality and timing also show in communicative acts of other species that might be pleasurable, but also necessary for survival. Sociality and timing often co-occur, but their shared phylogenetic trajectory is unknown: How, when, and why did they become so tightly linked? Answering these questions is complicated by several constraints; these include the use of divergent operational definitions across fields and species, the focus on diverse mechanistic explanations (e.g., physiological, neural, or cognitive), and the frequent adoption of anthropocentric theories and methodologies in comparative research. These limitations hinder the development of an integrative framework on the evolutionary trajectory of social timing and make comparative studies not as fruitful as they could be. Here, we outline a theoretical and empirical framework to test contrasting hypotheses on the evolution of social timing with species-appropriate paradigms and consistent definitions. To facilitate future research, we introduce an initial set of representative species and empirical hypotheses. The proposed framework aims at building and contrasting evolutionary trees of social timing toward and beyond the crucial branch represented by our own lineage. Given the integration of cross-species and quantitative approaches, this research line might lead to an integrated empirical-theoretical paradigm and, as a long-term goal, explain why humans are such socially coordinated animals.
Topics: Animals; Humans; Phylogeny; Biological Evolution; Social Behavior; Hominidae
PubMed: 37419011
DOI: 10.1016/j.plrev.2023.06.006 -
Journal of Sex Research Jul 2023Masturbation is one of the most common sexual behaviors in humans. It is also a phylogenetically widespread trait of various other mammalian and some non-mammalian... (Review)
Review
Masturbation is one of the most common sexual behaviors in humans. It is also a phylogenetically widespread trait of various other mammalian and some non-mammalian species. Several hypotheses have been proposed aiming to explain the function of masturbation in primates and other species. These were mainly based on observations of nonhuman primates such as rhesus macaques or bonobos and rodents such as African ground squirrels. Based on these observations various scholars suggested that masturbation improves ejaculate quality, decreases the risk of contracting sexually transmitted infections or is merely a by-product of sexual arousal and thus an alternate outlet to copulation. While these theories may explain some facets of masturbation in some species, they do not explain why masturbation is so widespread and has developed in various species as well as our hominid ancestors. Moreover, the research on which these theories are based is scarce and heavily focused on male masturbation, while female masturbation remains largely unexplored. This sex difference may be responsible for the one-sided theorizing that attributes a specific biological benefit to masturbation. We propose that the widespread prevalence of masturbation in the animal kingdom may be better explained by viewing masturbation as a primarily self-reinforcing behavior that promotes pleasure both in human and in nonhuman species.
Topics: Animals; Female; Male; Humans; Masturbation; Macaca mulatta; Sexual Behavior; Pleasure; Mammals
PubMed: 35316107
DOI: 10.1080/00224499.2022.2044446 -
Nature Human Behaviour Aug 2023Pleasure is a fundamental driver of human behaviour, yet its neural basis remains largely unknown. Rodent studies highlight opioidergic neural circuits connecting the...
Pleasure is a fundamental driver of human behaviour, yet its neural basis remains largely unknown. Rodent studies highlight opioidergic neural circuits connecting the nucleus accumbens, ventral pallidum, insula and orbitofrontal cortex as critical for the initiation and regulation of pleasure, and human neuroimaging studies exhibit some translational parity. However, whether activation in these regions conveys a generalizable representation of pleasure regulated by opioidergic mechanisms remains unclear. Here we use pattern recognition techniques to develop a human functional magnetic resonance imaging signature of mesocorticolimbic activity unique to states of pleasure. In independent validation tests, this signature is sensitive to pleasant tastes and affect evoked by humour. The signature is spatially co-extensive with mu-opioid receptor gene expression, and its response is attenuated by the opioid antagonist naloxone. These findings provide evidence for a basis of pleasure in humans that is distributed across brain systems.
Topics: Humans; Pleasure; Brain; Emotions; Nucleus Accumbens; Prefrontal Cortex
PubMed: 37386105
DOI: 10.1038/s41562-023-01639-0 -
American Journal of Epidemiology Apr 2024The World Health Organization specifies that sexual health requires the potential for pleasurable and safe sexual experiences. Yet epidemiologic research into sexual...
The World Health Organization specifies that sexual health requires the potential for pleasurable and safe sexual experiences. Yet epidemiologic research into sexual pleasure and other positive sexual outcomes has been scant. In this commentary, we aim to support the development and adoption of sex-positive epidemiology, which we define as epidemiology that incorporates the study of pleasure and other positive features alongside sexually transmitted infections and other familiar negative outcomes. We first call epidemiologists' attention to the potential role that stigma plays in the suppression of sex-positive research. We further describe existing measures of sex-positive constructs that may be useful in epidemiologic research. Finally, the study of sex-positive constructs is vulnerable to biases that are well-known to epidemiologists, especially selection bias, information bias, and confounding. We outline how these biases influence existing research and identify opportunities for future research. Epidemiologists have the potential to contribute a great deal to the study of sexuality by bringing their considerable methodological expertise to long-standing challenges in the field. We hope to encourage epidemiologists to broaden their sexual health research to encompass positive outcomes and pleasure.
PubMed: 38634632
DOI: 10.1093/aje/kwae054 -
Journal of Personality and Social... Jul 2023Although humans are hard-wired to pursue sensory pleasure, they show considerable heterogeneity in their moral evaluations of sensory pleasure. In some societies,...
Although humans are hard-wired to pursue sensory pleasure, they show considerable heterogeneity in their moral evaluations of sensory pleasure. In some societies, sensory pleasure is pursued without any moral inhibition, but in other societies, it is considered to be immoral and actively suppressed. This research investigates the moral motives behind the suppression of sensory consumption. Is the suppression of sensory consumption caused by the moral motive to promote social justice or the moral motive to promote social order? We test these two competing accounts through country-level archival data and seven preregistered controlled experiments. We find robust evidence that the social-order emphasizing binding moral foundations (authority, loyalty, and purity; Haidt, 2007) suppress sensory consumption. Consequently, individuals and societies that adhere to the binding values are less likely to consume sensory products such as alcohol, tobacco, soda, fragrances, and sex toys. These effects are mediated by prescriptive moral beliefs and feelings of shame. We also identify several moderators of the moral suppression of sensory consumption. Binding values do not suppress sensory consumption after moral licensing. The effects of binding values on sensory consumption attenuate when the products are framed as status-affirming. Finally, while binding values suppress sensory consumption that is personal, they do not suppress sensory consumption that is shared. Altogether, our findings show that social-order emphasizing moral beliefs in society can inhibit the pursuit of pleasure and change consumption patterns in the economy. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
Topics: Humans; Morals; Emotions; Group Processes; Pleasure; Shame
PubMed: 36355686
DOI: 10.1037/pspp0000450 -
Proceedings of the National Academy of... Jun 2024Pleasure and pain are two fundamental, intertwined aspects of human emotions. Pleasurable sensations can reduce subjective feelings of pain and vice versa, and we often...
Pleasure and pain are two fundamental, intertwined aspects of human emotions. Pleasurable sensations can reduce subjective feelings of pain and vice versa, and we often perceive the termination of pain as pleasant and the absence of pleasure as unpleasant. This implies the existence of brain systems that integrate them into modality-general representations of affective experiences. Here, we examined representations of affective valence and intensity in an functional MRI (fMRI) study ( = 58) of sustained pleasure and pain. We found that the distinct subpopulations of voxels within the ventromedial and lateral prefrontal cortices, the orbitofrontal cortex, the anterior insula, and the amygdala were involved in decoding affective valence versus intensity. Affective valence and intensity predictive models showed significant decoding performance in an independent test dataset ( = 62). These models were differentially connected to distinct large-scale brain networks-the intensity model to the ventral attention network and the valence model to the limbic and default mode networks. Overall, this study identified the brain representations of affective valence and intensity across pleasure and pain, promoting a systems-level understanding of human affective experiences.
Topics: Humans; Pleasure; Male; Magnetic Resonance Imaging; Female; Pain; Adult; Brain; Brain Mapping; Young Adult; Amygdala; Emotions; Prefrontal Cortex; Affect
PubMed: 38857402
DOI: 10.1073/pnas.2310433121 -
Journal of Clinical Medicine Aug 2023It is with great pleasure and enthusiasm that I introduce this Special Issue of the , entitled "Non-invasive Respiratory Support: How to Get It Right in Clinical...
It is with great pleasure and enthusiasm that I introduce this Special Issue of the , entitled "Non-invasive Respiratory Support: How to Get It Right in Clinical Medicine" [...].
PubMed: 37629286
DOI: 10.3390/jcm12165243 -
Nicotine & Tobacco Research : Official... May 2024Subjective experience of e-cigarettes may be an important factor in helping people who use combustible cigarettes switch completely to e-cigarettes to reduce harms from...
INTRODUCTION
Subjective experience of e-cigarettes may be an important factor in helping people who use combustible cigarettes switch completely to e-cigarettes to reduce harms from smoking. This paper describes a novel two-stage analysis using pleasure and satisfaction responses from Ecological Momentary Assessments (EMA) of both cigarette and e-cigarette use to predict future cigarette and e-cigarette tobacco use.
METHODS
This observational study included adult users of cigarettes and e-cigarettes who provided 7-days of EMA, capturing cigarette and e-cigarette use, followed by biweekly reports of cigarette and e-cigarette use over one year. Participants were 279 adults who provided both cigarette and e-cigarette responses during the EMA. We employed a two-stage analytic approach in which EMA data were used to predict subsequent levels of cigarette and e-cigarette use. In the first stage, EMA responses of cigarette and e-cigarette events were modeled via a mixed-effects location scale (MELS) model to yield summaries of participants' means and variability on event-related ratings of pleasure and satisfaction. These EMA summaries served as predictors in the second stage analysis of the biweekly post-EMA longitudinal cigarette and e-cigarette use data.
RESULTS
EMA pleasure and satisfaction ratings were similar for both products and predicted both longitudinal cigarette and e-cigarette use, even after controlling for baseline cigarette and e-cigarette dependence. Relatively higher levels of satisfaction with e-cigarettes were associated with greater decreases in cigarette use over time.
CONCLUSIONS
Pleasure and satisfaction are important predictors of subsequent cigarette and e-cigarette use.
IMPLICATIONS
Experienced subjective pleasure and satisfaction from e-cigarettes relative to cigarettes may be an important factor in helping individuals who smoke to switch completely to e-cigarettes as a harm reduction approach. In order to help sustain complete product switching and reduce dual use or relapse to smoking, e-cigarettes may need to deliver more satisfaction to the user compared to that experienced from cigarettes.
PubMed: 38775349
DOI: 10.1093/ntr/ntae121 -
Facial Plastic Surgery : FPS Jun 2024It gives us great pleasure to guest edit this special edition on The Disfigured Face. We present a range of manuscripts covering the surgical and non-surgical aspects of...
It gives us great pleasure to guest edit this special edition on The Disfigured Face. We present a range of manuscripts covering the surgical and non-surgical aspects of managing facial paralysis. We are privileged to include articles from internationally renowned surgeons. We hope our readers enjoy reading these articles and should there be any questions, or errors, please do not hesitate to contact us Best wishes Eamon Shamil and Peter Andrews Facial Reanimation Multidisciplinary Team The Royal National ENT Hospital, University College London Hospitals NHS Foundation Trust, England.
PubMed: 38834175
DOI: 10.1055/a-2338-0797 -
Neuroscience and Biobehavioral Reviews Sep 2023Anhedonia, as evidenced by impaired pleasurable response to reward, reduced reward motivation, and/or deficits in reward-related learning, is a common feature of... (Review)
Review
Anhedonia, as evidenced by impaired pleasurable response to reward, reduced reward motivation, and/or deficits in reward-related learning, is a common feature of depression. Such deficits in reward processing are also an important clinical target as a risk factor for depression onset. Unfortunately, reward-related deficits remain difficult to treat. To address this gap and inform the development of effective prevention and treatment strategies, it is critical to understand the mechanisms that drive impairments in reward function. Stress-induced inflammation is a plausible mechanism of reward deficits. The purpose of this paper is to review evidence for two components of this psychobiological pathway: 1) the effects of stress on reward function; and 2) the effects of inflammation on reward function. Within these two areas, we draw upon preclinical and clinical models, distinguish between acute and chronic effects of stress and inflammation, and address specific domains of reward dysregulation. By addressing these contextual factors, the review reveals a nuanced literature which might be targeted for additional scientific inquiry to inform the development of precise interventions.
Topics: Humans; Anhedonia; Motivation; Learning; Reward; Inflammation
PubMed: 37419230
DOI: 10.1016/j.neubiorev.2023.105307