-
Photodiagnosis and Photodynamic Therapy Dec 2023This study aimed to compare objective refractive errors and keratometry measurements obtained using the Nidek OPD-Scan II aberrometer/topographer and Topcon KR 8900...
BACKGROUND
This study aimed to compare objective refractive errors and keratometry measurements obtained using the Nidek OPD-Scan II aberrometer/topographer and Topcon KR 8900 autorefractokeratometer.
METHODS
The right eye medical records of 176 patients aged 18-35 years who were admitted to our clinic as refractive surgery candidates were tested for refractive status and keratometry measurements with a Nidek OPD-Scan II aberrometer/topographer and a standard table-top autorefractokeratometer (Topcon KR 8900) before and after the induction of cycloplegia. Patients who had undergone any eye surgery and had hereditary, ectatic, or acquired corneal pathology were excluded. Refractive data were compared as spheres, cylinders, spherical equivalents, and power vectors before and after the induction of cycloplegia. Flat and steep keratometry (K1-K2) readings were recorded in diopters (D) and axis degrees, respectively, for each eye.
RESULTS
The spherical, cylindrical, spherical equivalence, J0-J45 vector values and K1-K2 readings (D, axis) between the two devices were statistically significant before and after the induction of cycloplegia (p<0.05). Bland-Altman analysis identified mean differences (95%CI of limits of agreement) of 0.77 (-0,57 to 2,11) in sphere, 0.74 (-0,54 to 2,01) in spherical equivalent, -0,07 (-0,41 to 0,26) in J0 vector, 0,06 (-0,31 to 0,43) in J45 vector, -0,16 (-0,66 to 0,33) in K1, -0,23 (-0,79 to 0,33) in K2 values before induction of cycloplegia.
CONCLUSION
The refractive and keratometry results of the Nidek OPD Scan II system and Topcon KR 8900 standard table-top autorefractokeratometer are not interchangeable in healthy adult population before and after induction of cycloplegia.
Topics: Adult; Humans; Photochemotherapy; Photosensitizing Agents; Refraction, Ocular; Vision Tests; Refractive Errors; Reproducibility of Results
PubMed: 37459941
DOI: 10.1016/j.pdpdt.2023.103712 -
Veterinary Ophthalmology Sep 2023Assess the refractive states of donkeys and goats.
PURPOSE
Assess the refractive states of donkeys and goats.
METHODS
Forty-two donkeys and 28 goats were enrolled. The mean ± SD ages were 7.68 ± 7.33 years for donkeys and 4.26 ± 2.33 years for goats. Seven donkeys and one goat were <6 months old. Retinoscopy was performed in alert animals, following cycloplegia in goats but not in donkeys. Normality was determined using the Kolmogorov-Smirnov test. The two primary meridians and two eyes were compared using Pearson's correlation and paired Student's t-tests. The association between refractive states and age was examined using one-way ANOVA in donkeys and a paired Student's t-test in goats. One-sample t-tests were conducted to assess if the refractive error distributions were significantly different from "0".
RESULTS
The mean ± SD spherical equivalent (SE) refractive errors of the right and left donkey eyes were -0.80 ± 1.03 D and -0.35 ± 0.95 D, respectively. The majority (86%) of the donkeys had an astigmatic refraction and eight (19%) had anisometropia. The mean SE refractive errors of the right and left goat eyes were -0.15 ± 1.1 D and -0.18 ± 1.2 D, respectively. The majority (54%) of the goat eyes had an astigmatic refraction and five (18%) had anisometropia. The right and left eye SE refractive errors were positively correlated in both species (both p = .9). Age was not correlated with refractive error in both donkeys (p = .09) and goats (p = .6).
CONCLUSIONS
Both goats and donkeys are emmetropic.
Topics: Animals; Retinoscopy; Anisometropia; Equidae; Goats; Refractive Errors; Refraction, Ocular; Prevalence; Goat Diseases
PubMed: 37386869
DOI: 10.1111/vop.13126 -
Die Ophthalmologie Nov 2023Glaucoma is not a rare entity but because very few symptoms occur and visual field defects are frequently first recognized at a late stage, a large proportion of... (Review)
Review
BACKGROUND
Glaucoma is not a rare entity but because very few symptoms occur and visual field defects are frequently first recognized at a late stage, a large proportion of glaucoma diseases remain undetected. The aim of this study was to identify the proportion of undiagnosed glaucoma in German population-based cohort studies and to contextualize them in the context of the literature.
MATERIAL AND METHODS
The prevalence of glaucoma in the Gutenberg Health Study (GHS) and the age-related investigations on health of the University of Regensburg (AugUR) was evaluated based on visual field examinations and optic disc color photography according to the ISGEO criteria. Furthermore, the self-reported glaucoma diagnoses were collected and the proportion of undiagnosed glaucoma was determined.
RESULTS
The proportion of undiagnosed glaucoma was 55% in the GHS, and 53% in the AugUR study. The results correlate with results from previous studies from other countries in which the proportion of unrecognized glaucoma ranged from 33% to 78%. In the GHS and the AugUR study the proportion of undiagnosed glaucoma was higher in younger age groups and in women.
DISCUSSION
Roughly every second case of glaucoma is undetected. As the symptoms are often nonspecific or take a long time to appear, there is a risk of advanced glaucomatous visual field defects or blindness due to a lack of glaucoma awareness. Studies have shown that a systematic screening can halve this risk.
Topics: Humans; Female; Intraocular Pressure; Glaucoma; Visual Field Tests; Visual Fields; Optic Disk; Vision Disorders
PubMed: 37847376
DOI: 10.1007/s00347-023-01943-0 -
Ocular Immunology and Inflammation Sep 2023The aim of the study is to analyze visual fields defects (VFDs) in epidemic retinitis (ER).
AIM
The aim of the study is to analyze visual fields defects (VFDs) in epidemic retinitis (ER).
METHODS
Patients with ER and Humphrey's visual field (HFA) 30-2 performed after resolution were studied. VFD severity grading was performed. Patients treated with oral doxycycline (Group-A) versus doxycycline-steroids (group-B) were compared.
RESULTS
Thirty-five eyes of 25 patients were studied. Nasal, inferior, temporal and central VFD were seen in 19 (54.2%), 13 (37.1%), 7 (20%) and 6 (17.1%) eyes, respectively. Grade 0, 1, 2 and 3 VFDs were seen in 4 (11.4%), 15 (42.8%), 12 (34.2%) and 4 (11.4%) eyes respectively. Seven eyes with ≥1 year of follow-up post-resolution also showed grade 0-3 scotomas. Mean severity of scotoma was grade 1.15 (Median: 1) and 1.42 (Median: 1.5) in groups A (n = 13) and B (n = 14), respectively (p = .637).
CONCLUSION
ER can cause VFD persisting long after resolution. Treatment with oral doxycycline without steroids was non-inferior to combined treatment with respect to VFD.
Topics: Humans; Visual Fields; Doxycycline; Scotoma; Visual Field Tests; Vision Disorders; Retinitis
PubMed: 35708453
DOI: 10.1080/09273948.2022.2084422 -
Journal of Cataract and Refractive... Sep 2023To compare the visual performance, spectacle independence, and subjective visual quality of 2 enhanced monofocal intraocular lenses (IOLs): Eyhance ICB00 and ZOE...
PURPOSE
To compare the visual performance, spectacle independence, and subjective visual quality of 2 enhanced monofocal intraocular lenses (IOLs): Eyhance ICB00 and ZOE Primus-HD.
SETTING
Ophthalmology Department, San Raffaele Scientific Institute, Milan, Italy.
DESIGN
Prospective case series.
METHODS
Patients without ocular comorbidities and corneal astigmatism <0.75 diopters (D) undergoing cataract surgery with bilateral implantation of enhanced monofocal Eyhance and ZOE were included. 6 months postoperatively, the following parameters were analyzed: subjective and objective refraction; monocular and binocular corrected (4 m) and uncorrected (UDVA) distance visual acuities; corrected distance, intermediate (66 cm), and near (40 cm) visual acuities, as well as uncorrected intermediate (UIVA) and uncorrected near (UNVA) visual acuities; photopic contrast sensitivity; binocular defocus curve; halo and glare perception; and spectacle independence.
RESULTS
100 eyes of 50 patients were evaluated (25 patients per IOL group). The 2 IOLs showed superimposable visual performances, without significant differences in terms of refractive and visual outcomes, defocus curves, contrast sensitivity, scores of vision quality, and spectacle independence. Of note, monocular and binocular UDVA was excellent in both groups. The 2 IOL models achieved satisfactory binocular UIVA, with more than 70% of patients reaching a binocular UIVA of ≤0.1 logMAR. Up to 84% of patients eventually declared to feel comfortable frequently while staying at intermediate distance.
CONCLUSIONS
The general visual outcome of the Eyhance ICB00 and the ZOE Primus-HD enhanced monofocal IOLs is similar, with special reference to the satisfactory spectacle independence for intermediate distance.
Topics: Humans; Lens Implantation, Intraocular; Phacoemulsification; Prospective Studies; Lenses, Intraocular; Visual Acuity; Refraction, Ocular; Prosthesis Design; Patient Satisfaction; Vision, Binocular
PubMed: 37322813
DOI: 10.1097/j.jcrs.0000000000001239 -
Translational Vision Science &... Jul 2023To investigate whether the trajectories of saccadic eye movements (SEMs) significantly differ between glaucoma patients and controls.
PURPOSE
To investigate whether the trajectories of saccadic eye movements (SEMs) significantly differ between glaucoma patients and controls.
METHODS
SEMs were recorded by video-based infrared oculography in 53 patients with glaucoma and 41 age-matched controls. Participants were asked to bilaterally view 24°-horizontal, 14°-vertical, and 20°-diagonal eccentric Goldmann III-sized stimuli. SEMs were evaluated with respect to the saccadic reaction time (SRT), the mean velocity, amplitude, and two novel measures: departure angle (DA) and arrival angle (AA). These parameters were compared between the groups and the associations of SEM parameters with glaucoma parameters and integrated visual field defects were investigated.
RESULTS
Glaucoma patients exhibited increased mean SRT, DA, and AA values compared with controls for 14°-vertical visual targets (P = 0.05, P < 0.01, and P < 0.01, respectively). The SRT, DA, and AA were significantly associated with the mean and pattern standard deviations of perimetry and with the mean RNFL thickness by OCT (all P < 0.001). Glaucoma was associated with the AA (P = 0.05) and both the SRT (P = 0.01) and DA (P = 0.04) were associated with integrated visual field defects.
CONCLUSIONS
The saccadic trajectories of glaucoma patients depart in an erroneous path and compensate the disparity by deviating the trajectory at arrival.
TRANSLATIONAL RELEVANCE
The initial deviation that we observed (despite continuous exposure to the stimulus) suggests the disoriented spatial perception of glaucoma patients which may be relevant to difficulties encountered daily.
Topics: Humans; Saccades; Visual Fields; Glaucoma; Visual Field Tests; Vision Disorders; Biometry
PubMed: 37440248
DOI: 10.1167/tvst.12.7.15 -
Clinical & Experimental Optometry Sep 2023Spherical aberration is an imperfection of the optical system of the human eye. The role of spherical aberration of the human eye in the quality of vision and... (Review)
Review
Spherical aberration is an imperfection of the optical system of the human eye. The role of spherical aberration of the human eye in the quality of vision and pseudoaccommodation is reviewed. Spherical aberration is an imperfection of the optical system of the human eye. In most cases, due to well-developed neuroadaptation, it is insignificant for the perception of the image. Nevertheless, its role in modern ophthalmology is far from straightforward. On the one hand, there are clinical scenarios in which an excess of spherical aberration degrades the retinal image and leads to a high dissatisfaction rate among patients.©Recently, there is a growing interest in the modulation of spherical aberration in the clinical setting. Modern intraocular lenses as well as laser refractive procedures are aimed at interfering with spherical aberrations of the optical system in order to increase range of pseudoaccommodation. Here, we review the role of spherical aberration of the human eye in the quality of vision and pseudoaccommodation.
Topics: Humans; Ophthalmology; Lenses, Intraocular; Refraction, Ocular; Vision, Ocular; Vision Tests
PubMed: 36822601
DOI: 10.1080/08164622.2022.2160235 -
Clinical & Experimental Optometry Aug 2023Physical activity is an essential part of childhood physical and mental development. Recent research identified visual problems associated with a sedentary lifestyle in...
CLINICAL RELEVANCE
Physical activity is an essential part of childhood physical and mental development. Recent research identified visual problems associated with a sedentary lifestyle in children in Ireland.
BACKGROUND
This study explored the association between visual function in children and their engagement with physical activities outside school.
METHODS
Participants were 1,626 schoolchildren (728 aged 6-7-years, 898 aged 12-13-years) in randomly selected schools in Ireland. Before data collection, parents/legal guardians of participants completed a standardised questionnaire reporting physical activity as no activity (mostly on screens), light activity (occasional walking/cycling), moderate activity (<3 hrs/week engaged in sports), or regular activity (>3hrs/week engaged in sports). Measurements included logMAR monocular visual acuities (with spectacles and pinhole), in the distance (3 m) and near (40 cm), stereoacuity (TNO stereo-test), cover test, and cycloplegic autorefraction (1% cyclopentolate).
RESULTS
Controlling for confounders (socioeconomic disadvantage and non-White ethnicity), linear regression analysis revealed presenting distance visual acuity, near visual acuity, and stereoacuity were significantly better amongst participants who reported regular physical activity rather than moderate, light or no activity in both 6-7-year-old and 12-13-year-old participants. Absence of clinically-significant refractive error (>-0.50D < 2.00D) was associated with regular physical activity. Participants presenting with visual impairment (better-eye vision <6/12) (odds ratio = 5.78 (2.72-12.29)), amblyopia (pinhole acuity ≤6/12 plus an amblyogenic factor) (odds ratio = 5.66 (2.33-13.76)), and participants at school without their spectacles (odds ratio = 2.20 (1.33-3.63)), were more likely to report no activity.
CONCLUSIONS
Children regularly engaged in physical activities, including sports; had better visual and stereoacuity; and were less likely to need spectacles. Visual impairment, amblyopia, and refractive error were associated with no physical activity. Spectacle wear compliance was associated with regular physical activity. Regular physical activity is an essential factor in childhood vision and addressing visual impairment in children is vital to increasing participation in sports and exercise. Socioeconomically disadvantaged and non-White communities would benefit most from these measures.
Topics: Child; Humans; Amblyopia; Exercise; Refractive Errors; Vision Disorders; Vision, Low; Visual Acuity; Adolescent
PubMed: 35952361
DOI: 10.1080/08164622.2022.2106780 -
Ophthalmic & Physiological Optics : the... Nov 2023Colour vision deficiencies (CVDs) indicate potential genetic variations and can be important biomarkers of acquired impairment in many neuro-ophthalmic diseases....
Colour vision deficiencies (CVDs) indicate potential genetic variations and can be important biomarkers of acquired impairment in many neuro-ophthalmic diseases. However, CVDs are typically measured with tests which possess high sensitivity for detecting the presence of a CVD but do not quantify its type or severity. In this study, we introduce Foraging Interactive D-prime (FInD), a novel computer-based, generalisable, rapid, self-administered vision assessment tool and apply it to colour vision testing. This signal detection theory-based adaptive paradigm computed test stimulus intensity from d-prime analysis. Stimuli were chromatic Gaussian blobs in dynamic luminance noise, and participants clicked on cells that contained chromatic blobs (detection) or blob pairs of differing colours (discrimination). Sensitivity and repeatability of FInD colour tasks were compared against the Hardy-Rand-Rittler and the Farnsworth-Munsell 100 hue tests in 19 colour-normal and 18 inherited colour-atypical, age-matched observers. Rayleigh colour match was also completed. Detection and discrimination thresholds were higher for atypical than for typical observers, with selective threshold elevations corresponding to unique CVD types. Classifications of CVD type and severity via unsupervised machine learning confirmed functional subtypes. FInD tasks reliably detect inherited CVDs, and may serve as valuable tools in basic and clinical colour vision science.
Topics: Humans; Color Vision Defects; Color Vision; Vision Tests; Machine Learning; Cardiovascular Diseases; Color Perception
PubMed: 37589437
DOI: 10.1111/opo.13210 -
Contact Lens & Anterior Eye : the... Apr 2024The current multi-study analysis combined data from three studies to quantify the relationship between the initial reaction to soft multifocal contact lens (MFCL) design...
PURPOSE
The current multi-study analysis combined data from three studies to quantify the relationship between the initial reaction to soft multifocal contact lens (MFCL) design types at dispensing and evaluate the predictability of overall vision satisfaction (OVS) and intention to purchase (ITP) after 1 week of wear.
METHOD
Three prospective studies tested MFCLs over 1-week of wear following the same protocol, using a range of potentially predictive ratings at dispensing, and both OVS and ITP at 1-week as an indicator acceptance level. In each study, two of MyDay® multifocal, clariti® 1 day multifocal, Biofinity® multifocal (worn as a daily disposable lens) or 1 DAY ACUVUE® MOIST MULTIFOCAL were dispensed for 1-week of daily wear. OVS was recorded on a 100-point VAS and ITP on a 5-point LIKERT scale. Fourteen possible predictors were entered in the statistical model, and predictability was assessed using Chi-square Automatic Interaction Detector (CHAID) statistical test.
RESULTS
A total of 210 participants (152 female & 58 male; 53.9 ± 6.5 years, range 41-71 years), representing 420 MFCL fits, equally distributed between emergent n = 65, established n = 70 and advanced n = 75 presbyopes, completed the studies. OVS on dispensing was the predictor of both OVS (p < 0.001) and ITP (p < 0.001) at 1-week. For OVS predictability, 70.8 % with OVS at dispensing > 91 points reported good OVS at 1-week and 73.4 % with OVS on dispensing ≤ 80 points reported poor OVS at 1-week. For ITP predictability, 74.6 % with OVS at dispensing > 94 points reported a positive ITP at 1-week and 65.9 % with OVS on dispensing ≤ 63 points reported negative ITP at 1-week.
CONCLUSION
Overall vision satisfaction at the time of dispensing MFCLs is a powerful indicator of both OVS and ITP after 1-week of wear. Initial patient subjective assessments provide a clinically useful indicator of the likeliness of success.
Topics: Humans; Male; Female; Visual Acuity; Prospective Studies; Vision, Ocular; Contact Lenses, Hydrophilic; Presbyopia
PubMed: 38216392
DOI: 10.1016/j.clae.2023.102105