-
Orthodontics & Craniofacial Research May 2024To explore the association between third molar agenesis and supernumerary tooth formation in a white-European population.
OBJECTIVES
To explore the association between third molar agenesis and supernumerary tooth formation in a white-European population.
MATERIALS AND METHODS
A record review in various orthodontic clinics identified 380 eligible white-European individuals, half of whom had non-syndromic permanent supernumerary teeth (122 males and 68 females, totalling 244 supernumerary teeth; median age: 13.1, iqr: 1.5 years), and the other half were age- and sex-matched controls with full dentition, excluding the third molars. Tooth sequences were identified in panoramic radiographs.
RESULTS
In the supernumerary group, approximately 80% of the individuals had a single supernumerary tooth, followed by those having two additional teeth. In both groups, there was no sexual dimorphism in third molar agenesis severity. The prevalence of third molar agenesis in the supernumerary group was similar to that of the control group (28/190 = 14.7% in both groups; p = 1.0). In total, 53 third molars were missing in the supernumerary group (n = 190) compared to 67 in the control group (n = 190; p = .862). The ratio of bilateral to unilateral third molar agenesis was significantly lower in the supernumerary group than in the control group (1.0 vs. 3.7, respectively; p = .026).
CONCLUSION
The presence of supernumerary teeth did not significantly alter the likelihood of third molar agenesis or its severity. Bilateral third molar agenesis was considerably less prevalent in individuals with supernumerary teeth compared to controls. The present novel findings have important clinical and developmental implications.
PubMed: 38721988
DOI: 10.1111/ocr.12807 -
Journal of the Mechanical Behavior of... Dec 2023This study aims to enhance the mechanical stability of restored molar teeth with class II occlusal-distal (OD) cavities. We seek to achieve this goal through a...
OBJECTIVES
This study aims to enhance the mechanical stability of restored molar teeth with class II occlusal-distal (OD) cavities. We seek to achieve this goal through a comprehensive investigation of three primary factors: (1) the choice of restoration material properties, (2) internal cavity geometries, and (3) the impact of double-layered restoration configurations.
METHODS
To achieve our objectives, we initiated by creating two-dimensional (2D) models of restored teeth featuring class II OD cavities, utilizing scanned and segmented images of maxillary molar teeth. We drew 2D profiles of dentine and enamel, which were then imported into finite element analysis (FEA) software. To explore various cavity geometries, we implemented a total of thirteen different designs, encompassing straight, oblique, grooved, curved, and double-layered configurations. We utilized a semi-circular stone to simulate the application of contact load on the restored tooth. We applied identical boundary conditions and contact loading across all models. To assign material properties, we developed a Python code, enabling the automatic assignment of seven elastic moduli ranging from 2 GPa to 26 GPa to the restoration materials. Meanwhile, constant material properties were assigned to the enamel and dentine. In total, we conducted 133 FEA simulations to comprehensively analyse the effects of the aforementioned factors on the strength and performance of restored molar teeth.
RESULTS
Our analysis revealed two key factors significantly influencing the mechanical resistance of treated teeth, particularly in the presence of a crack or debonding: (1) the marginal geometry of the OD cavity and (2) the elastic modulus of the restorative material. However, altering the internal cavity angle and implementing a double-layered restoration did not significantly influence the restored tooth's overall strength and performance in the face of crack or debonding situations.
SIGNIFICANCE
The findings of this study have substantial implications for designing and restoring class II OD cavities to enhance resistance to cracks or debonding. The use of curved marginal geometries in restoration design can significantly improve fracture resistance, with double-curved geometries reducing stress concentrations by approximately 43% compared to straight cavities. These results offer valuable guidance for strengthening the structural integrity of restored teeth, calling for further experimental investigations to explore practical applications and benefits.
Topics: Finite Element Analysis; Composite Resins; Software; Elastic Modulus; Molar; Stress, Mechanical; Dental Restoration, Permanent; Dental Stress Analysis
PubMed: 37847958
DOI: 10.1016/j.jmbbm.2023.106191 -
International Journal of Legal Medicine May 2024Different studies have established that the mineralization stages of the second mandibular molar can be used in forensic age estimation. Nowadays, the estimate's...
Different studies have established that the mineralization stages of the second mandibular molar can be used in forensic age estimation. Nowadays, the estimate's accuracy is an ethical concern, producing as few false positives (individuals incorrectly classified as older than a determined threshold) and false negatives (individuals incorrectly classified as younger than a determined threshold) as possible. Some have hypothesized that changes in teeth number may influence tooth mineralization, altering the age estimate process. This paper analyzes whether third molar agenesis affects the second mandibular molar mineralization time frame. To do so, 355 orthopantomograms were evaluated for third molar agenesis, and the second mandibular molar mineralization stage was assessed using the Demirjian stages. Student's t-test was used to compare the difference in the mean age at which the various stages of 37 mineralization were reached in the groups with and without third molar agenesis. The level of statistical significance was set at 5%. The results pointed to a delay in second mandibular molar mineralization in the case of agenesis, suggesting the need to consider this when estimating age using dental techniques.
Topics: Humans; Molar, Third; Age Determination by Teeth; Molar; Tooth Calcification; Radiography, Panoramic
PubMed: 37994924
DOI: 10.1007/s00414-023-03128-5 -
Clinical, Cosmetic and Investigational... 2023The aim of this study was to determine the prevalence of mandibular third molar malposition and its impact in relation to the lower second molar using panoramic...
OBJECTIVE
The aim of this study was to determine the prevalence of mandibular third molar malposition and its impact in relation to the lower second molar using panoramic radiography.
METHODS AND MATERIALS
This was a cross-sectional descriptive study of 353 panoramic images of patients who visited the Dental Clinic of the International University of Rabat. Panoramic images were analyzed in order to determine the number of second molar pathologies associated with the positions of third molars. The following radiographic lesions on the second molar were recorded: caries, root resorption and distal alveolysis. The Chi-square test was used to assess the association between different variables.
RESULTS
Of these 353 radiographies, 169 were males, ie, 48%, and 184 were females, ie, 52%. The age range was from 18 to 63 years. The prevalence of the impacted position of the lower third molar was noted in 60%. Distal caries on the second mandibular molar was present in 47.5% of instances having an impacted third molar. Caries was present in 65.5% of wisdom teeth in a normal position and was also present in 79.6% of the impacted teeth. This difference was statistically significant with p = 0.01. The angulation of the third molar is a factor of caries of the second molar: 58.56% of them were carious. Of all the teeth in association with an angulation, 72.03% showed distal alveolysis in the second molar. In addition, root resorption was found in 20.4% of second molars linked to a wisdom tooth in all angulation occurrences.
CONCLUSION
It has been noted that among the pathologies seen on the mandibular second molar, distal alveolysis accounts for the majority of cases (58%), followed by caries (47.5%) and root resorption (13.3%). This study illustrated the importance of performing Orthopantomogram X-rays at each new consultation in patients over the age of 18.
PubMed: 37869067
DOI: 10.2147/CCIDE.S420765 -
Medicina Oral, Patologia Oral Y Cirugia... Jul 2024Brain-derived neurotrophic factor (BDNF) is a factor that implicate in the pathophysiology and treatment of depression and anxiety. The aim of this study was to... (Randomized Controlled Trial)
Randomized Controlled Trial
BACKGROUND
Brain-derived neurotrophic factor (BDNF) is a factor that implicate in the pathophysiology and treatment of depression and anxiety. The aim of this study was to determine the relationship between dental anxiety and BDNF serum level through impacted third molar surgery.
MATERIAL AND METHODS
In this randomized, double-blind, cross-sectional study, the sample included patients who had been admitted for the impacted third molar extraction under local anesthesia between January to November 2020. The primary predictor variable was serum BDNF level and the second predictor variable was dental anxiety scores before and after operation in patients. The primary outcome variable was the correlation between anxiety scores (APAIS, MDAS, STAI, VAS) and serum BDNF level. The sample included 55 patients (22 Male, 33 Female) aged 18 to 42 (24,2+5,55).
RESULTS
Comparison of pre-operative scores (APAIS, MDAS, STAI, VAS and BDNF) and post-operative scores were statistically significant (P < .05). Post-operatively, MDAS and VAS scores decreased, while BDNF levels and STAI scores increased compared to the preoperative scores. BDNF was not correlated with APAIS, MDAS, STAI, and VAS preoperatively and postoperatively.
CONCLUSIONS
There may be a relationship between serum BDNF level and dental anxiety scale, but, no correlation was found between them.
Topics: Humans; Brain-Derived Neurotrophic Factor; Female; Male; Cross-Sectional Studies; Adult; Tooth, Impacted; Molar, Third; Young Adult; Dental Anxiety; Double-Blind Method; Adolescent; Tooth Extraction; Preoperative Period
PubMed: 38907644
DOI: 10.4317/medoral.26558 -
Clinical Oral Investigations Mar 2024This study aimed to compare the impact of pre- and postoperative etoricoxib administration versus only postoperative on third molar extraction sequelae and oral health...
Comparing pre- and postoperative etoricoxib administration versus only postoperative on third molar extraction sequelae and oral health quality of life: a prospective quasi-experimental study.
OBJECTIVES
This study aimed to compare the impact of pre- and postoperative etoricoxib administration versus only postoperative on third molar extraction sequelae and oral health quality of life.
MATERIALS AND METHODS
This prospective quasi experimental study involved 56 patients, divided into a study group receiving preemptive etoricoxib 120 mg before surgery and postoperative etoricoxib 120 mg (n = 28), and a control group receiving preemptive placebo before surgery and postoperative etoricoxib 120 mg (n = 28). Follow-up assessments were conducted at 3- and 7-days post-surgery, recording swelling, trismus, and adverse events. Patients rated perceived pain using the visual analog scale (VAS) and completed an oral health-related quality of life (OHRQoL) questionnaire at specified intervals. Statistical analysis employed non-parametric tests (i.e., the Mann-Whitney test, Friedman test, and Wilcoxon sign test) with P < 0.05.
RESULTS
Significantly lower VAS scores were reported in the study group throughout the follow-up period (P < 0.05). Pharmacological protocol did not have a significant impact on postoperative edema and trismus (P > 0.05). However, double etoricoxib intake significantly improved postoperative quality of life on day 3 after surgery (P < 0.05).
CONCLUSIONS
Pre- and postoperative etoricoxib 120 mg intake in third molar surgery reduced postoperative pain and enhanced postoperative quality of life on day 3 after surgery. Importantly, it was equally effective in managing swelling and trismus compared to exclusive postoperative intake.
CLINICAL RELEVANCE
Preemptive etoricoxib use may decrease patient discomfort following impacted mandibular third molar extraction.
Topics: Humans; Etoricoxib; Molar, Third; Trismus; Quality of Life; Prospective Studies; Oral Health; Tooth Extraction; Pain, Postoperative; Tooth, Impacted; Edema
PubMed: 38489136
DOI: 10.1007/s00784-024-05614-5 -
BMC Oral Health Nov 2023This study aimed to assess the correlation between maxillary sinus proximity to root apices of maxillary molars and root resorption during molar distalization using...
BACKGROUND
This study aimed to assess the correlation between maxillary sinus proximity to root apices of maxillary molars and root resorption during molar distalization using clear aligner therapy (CAT).
MATERIALS AND METHODS
Thirty-eight cone beam computed tomography scans (CBCTs) obtained pre- (T0) and post-treatment (T1) from 19 adult patients (36.68 ± 13.50 years), who underwent maxillary molar distalization using Invisalign® aligners (Align Technology, Inc., San José, CA, USA) with a minimum of 2 mm distalization, were evaluated in this study At least 22 h of aligner wear per day was a main inclusion criterion. Sinus proximity and changes in root lengths were measured for 61 molars (183 roots). Spearman coefficient analysis was used for assessing correlation between sinus proximity and root resorption. The level of significance was set at p ≤ 0.05. The reproducibility of measurements was assessed by intraclass correlation coefficient (ICC).
RESULTS
Spearman coefficient revealed no significant correlation between sinus proximity and molar root resorption for mesiobuccal, distobuccal or palatal roots (p = 0.558, p = 0.334, p = 0.931, respectively).
CONCLUSION
There was no correlation between maxillary sinus proximity to root apices of maxillary molars and root resorption.
Topics: Adult; Humans; Root Resorption; Maxillary Sinus; Reproducibility of Results; Spiral Cone-Beam Computed Tomography; Maxilla; Tooth Root; Molar; Cone-Beam Computed Tomography; Orthodontic Appliances, Removable
PubMed: 37990186
DOI: 10.1186/s12903-023-03672-x -
Cureus Jul 2023The aim of this retrospective pilot study was to investigate the effects of premature loss of primary teeth on molar relationships and midline discrepancies in young...
AIM
The aim of this retrospective pilot study was to investigate the effects of premature loss of primary teeth on molar relationships and midline discrepancies in young patients and explore its potential implications for dental treatments, including orthodontics.
MATERIALS AND METHODS
A total of 550 study models from individuals seeking orthodontic treatment were evaluated, and 175 models met the inclusion criteria of mixed dentition. Each study model was examined for midline discrepancies, asymmetric molar relationships, and the impact of net premature tooth loss on the midline shift. Four investigators analyzed the data, and the error was minimized to less than 5%.
RESULTS
The study revealed that premature loss of primary first molars was significantly associated with the midline shift, while premature loss of canines and second molars did not show substantial associations with midline discrepancies. The concordance analysis between observed and expected molar classifications based on premature tooth loss indicated relatively low concordance for all three molar classes, with higher concordance observed in Class II molar relationships. Notably, premature loss of primary second molars showed higher concordance than premature loss of primary first molars.
CONCLUSION
This retrospective pilot study highlights the potential dental complications associated with premature loss of primary teeth. Premature loss of primary first molars was found to be significantly linked to the midline shift, while the premature loss of canines and second molars did not demonstrate significant midline discrepancies. The concordance analysis revealed limited agreement between observed and expected molar classifications based on premature tooth loss, with higher concordance observed in Class II molar relationships and primary second molars. Further research with larger prospective cohorts and digital model analyses is warranted to gain a better understanding of the impact of premature tooth loss on dental treatment outcomes. The findings underscore the importance of early detection and appropriate intervention to mitigate potential adverse effects on dental arch development and malocclusion.
PubMed: 37637675
DOI: 10.7759/cureus.42442 -
Archives of Oral Biology Sep 2024This paper investigates whether deciduous upper molars and lower canines have sexual dimorphic features, exploring these teeth' dimensions and the presence of...
OBJECTIVE
This paper investigates whether deciduous upper molars and lower canines have sexual dimorphic features, exploring these teeth' dimensions and the presence of Zuckerkandl's tubercle and Carabelli's cusp on the first and second upper molars.
DESIGN
We analyzed 64 pairs of dental plaster casts from 34 females and 30 males aged between 3 and 12 years. We measured the first and second deciduous upper molars and the lower deciduous canines (maximum mesiodistal and buccolingual length), and we registered the presence of the Zuckerkandl's tubercle and the Carabelli's cusp on the first and second upper molars, respectively.
RESULTS
Regarding the differentiation between sexes using Carabelli's cusp and Zuckerkandl's tubercle, the classification was not independent of Carabelli's cusp presence only for tooth 65 (p = 0.035). In all other teeth, whether for Carabelli's cusp or Zuckerkandl's tubercle, their presence was similar for both sexes. There were statistically significant differences between sexes (p < 0.05) for the buccolingual measurements of both upper second molars, the first right upper molar, and the right canine. The developed model allowed for a 64.1% accuracy in sex estimation.
CONCLUSIONS
The study suggests that while Carabelli's cusp and Zuckerkandl's tubercle in upper deciduous molars don't consistently differ between sexes, tooth size, particularly the buccolingual measurements of certain teeth, including upper deciduous molars and lower canines, may provide a more reliable criterion for sex estimation. The developed model depicted moderate accuracy, underscoring the need for a multifactorial approach when estimating sex from skeletal remains. It suggests that while dental features can contribute to sex estimation, they should be used in conjunction with other skeletal or molecular markers to improve accuracy.
Topics: Humans; Male; Female; Cuspid; Tooth, Deciduous; Molar; Child; Child, Preschool; Models, Dental; Odontometry; Sex Characteristics
PubMed: 38810388
DOI: 10.1016/j.archoralbio.2024.106006