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Revista Gaucha de Enfermagem 2021To identify symptoms of COVID-19 in adults in the scientific literature.
OBJECTIVE
To identify symptoms of COVID-19 in adults in the scientific literature.
METHOD
Systematic review of studies published from December 1, 2019 to April 21, 2020 from the Scopus, Web of Science and PubMed databases, in order to answer the following research question: "What are the symptoms caused by COVID-19 in adults?" using the keywords "Symptoms", "Clinical Manifestations", "Coronavirus", "COVID-19".
RESULTS
Of the total 105 references, 13 references that addressed the symptoms of COVID-19 were selected. Fever and normal or dry cough were symptoms present in all studies.
CONCLUSION
The symptoms identified in adult patients were fever, normal or dry cough, headache, pharyngalgia, dyspnea, diarrhea, myalgia, vomiting, sputum or expectoration, anxiety or chest pain, fatigue, nausea, anorexia, abdominal pain, rhinorrhea, runny nose or nasal congestion, dizziness, chills, systemic pain, mental confusion, hemoptysis, asthma, taste disorder, smell disorder, belching and tachycardia.
Topics: Adult; COVID-19; Cough; Cross-Sectional Studies; Diarrhea; Dyspnea; Fatigue; Fever; Humans; Middle Aged; Symptom Assessment
PubMed: 34037180
DOI: 10.1590/1983-1447.2021.20200205 -
Recenti Progressi in Medicina Jan 2020In recent years there has been an enormous development in the use of electronic cigarettes (e-cig). In Italy, in the 2019, the users of e-cig are about 900.000. E-cig... (Comparative Study)
Comparative Study
BACKGROUND
In recent years there has been an enormous development in the use of electronic cigarettes (e-cig). In Italy, in the 2019, the users of e-cig are about 900.000. E-cig users tend to overlook the absolute risk of the e-cig product in favor of the relative risk compared to traditional ones. This is also due to the fact that at the moment there are large knowledge gaps on the health effects of using e-cig. Recently reports have emerged regarding serious health adverse effects (AE) related to their use. As of December 2019, the American Centers for Disease Control and Prevention (CDC) reported 2409 cases of lung disease associated with the use of e-cig, and 52 deaths.
AIM
To summarize the available evidence on the health effects of electronic cigarettes.
METHODS
We searched systematic reviews (SR) of the literature published up to September 2019.
RESULTS
The systematic searches led to the identification of 14 SRs (1037 studies included of which 77 provided useful information for this review) that met the inclusion criteria. Given the heterogeneity of the comparisons and of the outcome measures considered, the results are described narratively. Effects on the respiratory system: cough, phlegm, asthma and bronchitis symptoms, cases of chronic bronchitis and COPD have also been reported. Effects on the oropharyngeal system: lesions in the oral cavity, villous black tongue, allergic reactions, endogenous formation of carcinogens, development of oral cancer. Effects on the cardiovascular system: increased heart rate, increased systolic and diastolic pressure. Effects on skin and annexes: squamous and pruritic dermatitis. Any adverse effect: the most frequently reported AEs are cough, dry mouth, shortness of breath, irritation of the mouth and throat and headache. Effects of exposure to e-cig passive smoking: increase in cotinine levels in exposed environments.
CONCLUSIONS
These results, based on evidence from very low to moderate, show a series of possible risks linked to the use of e-cig. However, there is a need for further well-conducted studies with longer follow-up periods to confirm these results.
Topics: Electronic Nicotine Delivery Systems; Humans; Risk; Tobacco Smoke Pollution; Vaping
PubMed: 31992902
DOI: 10.1701/3294.32651 -
Frontiers in Pharmacology 2022Integrative herbal medicine has been reported to have beneficial effects in the treatment of coronavirus disease 2019 (COVID-19). To compile up-to-date evidence of the...
Integrative herbal medicine has been reported to have beneficial effects in the treatment of coronavirus disease 2019 (COVID-19). To compile up-to-date evidence of the benefits and risks of herbal medicine for the treatment of COVID-19 symptoms. Eleven databases, including PubMed, Cochrane Register of Controlled Trials (CENTRAL), Embase, Allied and Complementary Medicine Database (AMED), Chinese National Knowledge Infrastructure Database (CNKI), Wanfang Database, and Chinese Science and Technique Journals Database (VIP), Research Information Service System (RISS), Korean Medical database (KMBase), Korean Association of Medical Journal database (KoreaMed), and OASIS database, were searched from 15 June, 2020, until 28 March 2022. Randomized controlled trials (RCTs), published in any language, reporting the efficacy and safety outcomes of herbal medicine in patients of all ages with a PCR-confirmed diagnosis of COVID-19 were included in this analysis. Data extraction and quality assessments were performed independently. Random-effects meta-analyses showed evidence of favorable effects of treatment with herbal medicine when added to standard treatment, versus standard treatment alone, on the total effective rate ( = 0.0001), time to remission from fever ( < 0.00001), rate of remission from coughing ( < 0.0001), fatigue ( = 0.02), sputum production ( = 0.004), improvement of manifestations observed on chest computed tomography scans ( < 0.00001), incidence of progression to severe COVID-19 ( = 0.003), all-cause mortality ( = 0.003), time to a negative COVID-19 coronavirus test ( < 0.0001), and duration of hospital stay ( = 0.0003). There was no evidence of a difference between herbal medicine added to standard treatment, versus standard treatment alone, on the rate of remission from symptoms such as a fever, sore throat, nasal congestion and discharge, diarrhea, dry throat, chills, and the rate of conversion to a negative COVID-19 coronavirus test. Meta-analysis showed no evidence of a significant difference in adverse events between the two groups. There was an unclear risk of bias across the RCTs included in this analysis, indicating that most studies had methodological limitations. Current evidence suggests that herbal medicine added to standard treatment has potential benefits in the treatment of COVID-19 symptoms but the certainty of evidence was low.
PubMed: 35795550
DOI: 10.3389/fphar.2022.906764 -
Geriatrie Et Psychologie... Jun 2020The COVID-19 pandemic affects older adults particularly severely. Our objective was to identify from the international literature the symptoms most commonly experienced...
The COVID-19 pandemic affects older adults particularly severely. Our objective was to identify from the international literature the symptoms most commonly experienced by older adults infected with SARS-CoV-2. This systematic literature review was conducted using MEDLINE between 1 December 2019 and 13 April 2020. The methodological quality analysis used a method dedicated to case series and case reports. Of the 260 articles initially identified, only two studies were ultimately included in the qualitative analysis. The mean age was relatively low, between 71 and 74 years on average. COVID-19 symptoms were as follows: fever, dry cough, dyspnoea, asthenia, anorexia, chest tightness, diarrhoea and, to a lesser extent, myalgia, pharyngitis, nausea, dizziness, headache, abdominal pain, and vomiting. Lymphopenia was noted from complete blood counts. In conclusion, this systematic review of the international literature reveals a lack of data about the semiology of COVID-19 in older adults, especially in very elderly frail people, who are normally considered to constitute the geriatric population. The national survey conducted by the Société Française de Gériatrie et Gérontologie will help bridge this semiological gap.
Topics: Aged; Aged, 80 and over; COVID-19; Coronavirus Infections; Frail Elderly; Humans; Pandemics; Pneumonia, Viral
PubMed: 33048052
DOI: 10.1684/pnv.2020.0890 -
Geriatrie Et Psychologie... Jun 2020The COVID-19 pandemic is particularly severe in older adults. Our objective was to identify, from international literature, the most common symptoms met in older adults...
The COVID-19 pandemic is particularly severe in older adults. Our objective was to identify, from international literature, the most common symptoms met in older adults infected with the SARS-CoV-2 virus. This systematic review of the literature was conducted using MEDLINE from December 1, 2019 to April 13, 2020. The analysis of methodological quality used a method dedicated to case series and case reports. Out of 260 articles initially identified, only two studies were finally included in the qualitative analysis. The mean age was relatively low, between 71 and 74 years on average. The symptoms of COVID-19 were as follows: fever, dry cough, dyspnea, asthenia, anorexia, chest tightness, diarrhea, and to a lesser extent myalgia, pharyngitis, nausea, dizziness, headache, abdominal pain and finally vomiting. Lymphopenia was found in the complete blood count. In conclusion, this systematic review of the international literature reveals a lack of data about the semiology of COVID-19 in older adults, especially in the frail oldest-old ones who commonly define the geriatric population. The national survey conducted by the French Society of Geriatrics and Gerontology will help fill this semiological gap.
Topics: Age Factors; Aged; Aged, 80 and over; COVID-19; Coronavirus Infections; Frail Elderly; Humans; Pandemics; Pneumonia, Viral
PubMed: 32554345
DOI: 10.1684/pnv.2020.0863 -
Indian Journal of Occupational and... 2019We report a 65 year old female patient who had presented with dry cough and shortness of breath for the last 5 years and had also received anti-tubercular therapy but...
We report a 65 year old female patient who had presented with dry cough and shortness of breath for the last 5 years and had also received anti-tubercular therapy but without any benefit. Evaluation revealed the presence of obstructive airway disease with nodular opacities in bilateral lungs. Histopathological examination including electron microscopy was suggestive of domestically acquired pneumoconiosis.A diagnosis of Gujjar lung was made based on history of exposure to wood smoke, characteristic histological and radiological features. Anti-tubercular therapy was stopped and bronchodilators were initiated along with removal from source of exposure to which she showed significant improvement. We also did a systematic review of literature pertaining to Gujjar lung.
PubMed: 31920264
DOI: 10.4103/ijoem.IJOEM_230_18