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The Science of the Total Environment Apr 2023Due to the rapidly increasing ridership and the relatively enclosed underground space, the indoor air quality (IAQ) in underground subway stations (USSs) has attracted... (Review)
Review
Due to the rapidly increasing ridership and the relatively enclosed underground space, the indoor air quality (IAQ) in underground subway stations (USSs) has attracted more public attention. The air pollutants in USSs, such as particulate matter (PM), CO and volatile organic compounds (VOCs), are hazardous to the health of passengers and staves. Firstly, this paper presents a systematic review on the characteristics and sources of air pollutants in USSs. According to the review work, the concentrations of PM, CO, VOCs, bacteria and fungi in USSs are 1.1-13.2 times higher than the permissible concentration limits specified by WHO, ASHRAE and US EPA. The PM and VOCs are mainly derived from the internal and outdoor sources. CO concentrations are highly correlated with the passenger density and the ventilation rate while the exposure levels of bacteria and fungi depend on the thermal conditions and the settled dust. Then, the online monitoring, fault detection and prediction methods of IAQ are summarized and the advantages and disadvantages of these methods are also discussed. In addition, the available control strategies for improving IAQ in USSs are reviewed, and these strategies are classified and compared from different viewpoints. Lastly, challenges of the IAQ management in the context of the COVID-19 epidemic and several suggestions for underground stations' IAQ management in the future are put forward. This paper is expected to provide a comprehensive guidance for further research and design of the effective prevention measures on air pollutants in USSs so as to achieve more sustainable and healthy underground environment.
Topics: Air Pollution, Indoor; Railroads; Carbon Dioxide; Environmental Monitoring; COVID-19; Particulate Matter; Air Pollutants; Volatile Organic Compounds; Bacteria; Fungi
PubMed: 36708828
DOI: 10.1016/j.scitotenv.2023.161781 -
BioMed Research International 2021Evidence on the carcinogenicity of coalmine dust in occupational settings is still conflicting. Therefore, we conducted this research to evaluate the mortality risk of... (Meta-Analysis)
Meta-Analysis
BACKGROUND
Evidence on the carcinogenicity of coalmine dust in occupational settings is still conflicting. Therefore, we conducted this research to evaluate the mortality risk of lung cancer for coalminers exposed to occupational dust when compared to population with no or low dust exposure.
METHODS
Databases of PubMed and Chinese National Knowledge Infrastructure as well as reference lists were searched updated to September 18, 2020. The enrolled articles should report lung cancer mortality risk for coalminers exposed to occupational dust. Basic information was extracted such as the author and publication year, area and ethnicity, the type and estimates of outcome, duration of follow-up, and the study design. The checklists from Agency for Healthcare Research and Quality and the Newcastle-Ottawa Scale were used for the assessment of quality and bias risk for descriptive studies, cohort studies, and case control studies, respectively. The overall relative risks were calculated while Begg's and Egger's tests and sensitivity analysis were performed to explore potential heterogeneity sources. Metaregression and subgroup analyses were also conducted to give more detailed information for the correlation between dust exposure and lung cancer mortality.
RESULTS
A total of 19 articles with 22 different studies (descriptive study, case control study, and cohort study) including 8909 observed deaths from 1964 to 2017 were enrolled with a significant heterogeneity ( = 95%, < 0.001). The pooled relative risk of mortality from lung cancer was 1.16 (1.03-1.30) for coalminers. Results of metaregression analysis indicated that the high heterogeneity among these enrolled studies might be caused by the ethnicity differences ( = 0.011). Subgroup analysis also indicated that the pooled estimate for Asian population in China was 4.94 (3.95-6.17) with = 39.3% and = 0.192. All these results suggested that exposure to occupational dust would significantly increase the mortality risk of lung cancer, especially for Asian population in China, which should be measured and controlled more strictly. . This systematic review and meta-analysis provides high-quality evidence that exposure to occupational dust might increase the mortality risk of lung cancer, especially for Asian populations in China. The magnitude of this effect is of major public health importance in view of the ubiquitous existence of coalmining industry in China and even in the world. However, these pooled estimates should be interpreted cautiously because of the high heterogeneity among these publications. . This study was supported by the National Key Research and Development Program of China (Grant No. 2016YFC1302501).
Topics: Coal; Coal Mining; Dust; Humans; Lung Neoplasms; Occupational Diseases; Occupational Exposure
PubMed: 33763477
DOI: 10.1155/2021/6624799 -
Toxicology Reports Dec 2023Heavy metals in street dust are one of the most important sources of pollutants in urban areas. This urban dust can be caused by industrial activities, traffic, erosion... (Review)
Review
BACKGROUND
Heavy metals in street dust are one of the most important sources of pollutants in urban areas. This urban dust can be caused by industrial activities, traffic, erosion of buildings, and fossil fuels. The aim of this systematic review is to evaluate the ecological risk of heavy metals in the dust of Iran's provinces.
METHODS
This study was conducted in February 2023 in order to investigate the environmental risks associated with heavy metals associated with dust particles in Iran. The present study was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Finally, 9 studies were extracted from the search databases.
RESULTS
The ecological risk of heavy metals in the present study was as follows: Cd (258.26؛ CI: 83.53, 433) >Pb (52.58؛ CI: 37.15, 68.02) >Cu (24.44؛ CI: 16.74, 32.14)>Ni (14.75؛ CI: 12.68, 16.82)>As (13.53؛ CI: 10.20, 16.85)>Zn (6.32؛ CI: 3.76, 8.87)>V (3.18؛ CI: 2.65, 3.72)>Cr (2.73؛ CI: 2.19, 3.27)>Co (1.94؛ CI: 1.13, 2.74). The mean ranking of the studied Pb ecological risk is as follows: Shiraz.> Tehran > Ahvaz > Ilam > Abadan > Dezful.
CONCLUSION
The ecological risk potential of Cd in Tehran was also much higher than the standard. Therefore, Tehran was the most polluted city studied in terms of the ecological risk potential of Cd (1611.41؛ CI: 1605.98, 1616.84) and Pb (86.54؛ CI: 71.46, 101.62). The average concentration as well as the ecological risk of Cr, Co, and V metals were lower than the standard. Therefore, controlling the sources of heavy metal emissions (especially lead and cadmium) is highly recommended.
PubMed: 38075013
DOI: 10.1016/j.toxrep.2023.11.007 -
Asia-Pacific Journal of Public Health Jul 2022We aimed to identify the contemporary prevalence of byssinosis through a systematic review. Medline, Web of Science, Embase, and Global Health databases were used to...
We aimed to identify the contemporary prevalence of byssinosis through a systematic review. Medline, Web of Science, Embase, and Global Health databases were used to identify studies published in any language between 2000 and 2019, reporting primary data on byssinosis among adults. We used the Joanna Briggs Institute checklist to estimate the risk of bias in studies and undertook a qualitative, narrative data analysis. The review considered the prevalence of byssinosis, chest tightness, and airflow obstruction in textile workers in low- and middle-income countries (LMICs). We found 26 relevant studies that included 6930 workers across 12 countries. Most of the studies (n = 19) were from Asia, and seven from African countries. Twenty-five studies were cross-sectional surveys while one was a cohort study. The prevalence of byssinosis was reported by 18 studies, and ranged from 8% to 38%, without any clear associations, at the group level, between the prevalence of byssinosis and durations of workers' exposures. Prevalence of chest tightness ranged between 4% and 58% and that of airflow obstruction between 10% and 30%. A strong correlation ( = 0.72) was found between prevalence of byssinosis and cotton dust levels. Our findings indicate that byssinosis remains a significant, contemporary problem in some parts of the textile sector in LMICs.
Topics: Adult; Byssinosis; Cohort Studies; Developing Countries; Dust; Gossypium; Humans; Prevalence; Pulmonary Disease, Chronic Obstructive; Textile Industry
PubMed: 35073782
DOI: 10.1177/10105395211073051 -
International Journal of Environmental... May 2022Health impact assessment (HIA) has been regarded as an important means and tool for urban planning to promote public health and further promote the integration of health... (Review)
Review
Health impact assessment (HIA) has been regarded as an important means and tool for urban planning to promote public health and further promote the integration of health concept. This paper aimed to help scientifically to understand the current situation of urban HIA research, analyze its discipline co-occurrence, publication characteristics, partnership, influence, keyword co-occurrence, co-citation, and structural variation. Based on the ISI Web database, this paper used a bibliometric method to analyze 2215 articles related to urban HIA published from 2012 to 2021. We found that the main research directions in the field were Environmental Sciences and Public Environmental Occupational Health; China contributed most articles, the Tehran University of Medical Sciences was the most influential institution, Science of the Total Environment was the most influential journal, Yousefi M was the most influential author. The main hotspots include health risk assessment, source appointment, contamination, exposure, particulate matter, heavy metals and urban soils in 2012-2021; road dust, source apposition, polycyclic aromatic hydrocarbons, air pollution, urban topsoil and the north China plain were always hot research topics in 2012-2021, drinking water and water quality became research topics of great concern in 2017-2021. There were 25 articles with strong transformation potential during 2020-2021, but most papers carried out research on the health risk assessment of toxic elements in soil and dust. Finally, we also discussed the limitations of this paper and the direction of bibliometric analysis of urban HIA in the future.
Topics: Bibliometrics; Dust; Health Impact Assessment; Iran; Publications
PubMed: 35627492
DOI: 10.3390/ijerph19105957 -
Environmental Science and Pollution... Mar 2022The negative health effects of cement plant exposure are well-known in industrial settings, but they are less well-known among the general public who live near plants.... (Review)
Review
The negative health effects of cement plant exposure are well-known in industrial settings, but they are less well-known among the general public who live near plants. The broad objective of the review was to provide a detailed systematic analysis of the global situation of the cement industry, including generation, pollution, impact on the natural ecosystem, technological and process improvements, sustainable models, the latest laws, challenges, needs, and ways forward. As an initial evaluation, a list of critical keywords was compiled, and a search of all accessible databases was conducted (i.e., Scopus, Web of Knowledge, Google Scholar). The manuscripts published in the journal between 2011 and 2021 were included. According to the findings, India is the second largest cement producer after China, with an installed capacity of 537 million tonnes and around 7.1 percent of the world's production, up from 337.32 million tonnes in 2019. NOx, SOx, CO, CO, HS, VOCs, dioxins, furans, and particulate matter are all common air pollutants from cement manufacturing. Other sources of dust particles include quarrying, blasting, drilling, trucking, cement plants, fuel production, packaging, path cleaning, and slabs. Other methods of reduction play an important part in decreasing industrial emissions, resulting in lower carbon and more sustainable products. The decision-making trial, in conjunction with the DEMATEL evaluation laboratory and the analytical hierarchy process (AHP) technique, will aid in determining the priority of climate alteration and mitigation options. Furthermore, employing sustainable techniques and technology, switching to alternative fuels will save 12% of total CO emissions by 2050.
Topics: Air Pollutants; Air Pollution; Ecosystem; Environment; Industry; Particulate Matter
PubMed: 35037150
DOI: 10.1007/s11356-022-18672-7 -
The Cochrane Database of Systematic... Sep 2020Asthma is a common long-term respiratory disease affecting approximately 300 million people worldwide. Approximately half of people with asthma have an important... (Meta-Analysis)
Meta-Analysis
BACKGROUND
Asthma is a common long-term respiratory disease affecting approximately 300 million people worldwide. Approximately half of people with asthma have an important allergic component to their disease, which may provide an opportunity for targeted treatment. Sublingual immunotherapy (SLIT) aims to reduce asthma symptoms by delivering increasing doses of an allergen (e.g. house dust mite, pollen extract) under the tongue to induce immune tolerance. Fifty-two studies were identified and synthesised in the original Cochrane Review in 2015, but questions remained about the safety and efficacy of sublingual immunotherapy for people with asthma.
OBJECTIVES
To assess the efficacy and safety of sublingual immunotherapy compared with placebo or standard care for adults and children with asthma.
SEARCH METHODS
The original searches for trials from the Cochrane Airways Group Specialised Register (CAGR), ClinicalTrials.gov, WHO ICTRP, and reference lists of all primary studies and review articles found trials up to 25 March 2015. The most recent search for trials for the current update was conducted on 29 October 2019.
SELECTION CRITERIA
We included parallel randomised controlled trials, irrespective of blinding or duration, that evaluated sublingual immunotherapy versus placebo or as an add-on to standard asthma management. We included both adults and children with asthma of any severity and with any allergen-sensitisation pattern. We included studies that recruited participants with asthma, rhinitis, or both, providing at least 80% of trial participants had a diagnosis of asthma. We selected outcomes to reflect recommended outcomes for asthma clinical trials and those most important to people with asthma. Primary outcomes were asthma exacerbations requiring a visit to the emergency department (ED) or admission to hospital, validated measures of quality of life, and all-cause serious adverse events (SAEs). Secondary outcomes were asthma symptom scores, exacerbations requiring systemic corticosteroids, response to provocation tests, and dose of inhaled corticosteroids (ICS).
DATA COLLECTION AND ANALYSIS
Two review authors independently screened the search results for included trials, extracted numerical data, and assessed risk of bias, all of which were cross-checked for accuracy. Any disagreements were resolved by discussion. We analysed dichotomous data as odds ratios (ORs) or risk differences (RDs) using study participants as the unit of analysis; we analysed continuous data as mean differences (MDs) or standardised mean differences (SMDs) using random-effects models. We considered the strength of evidence for all primary and secondary outcomes using the GRADE approach.
MAIN RESULTS
Sixty-six studies met the inclusion criteria for this update, including 52 studies from the original review. Most studies were double-blind and placebo-controlled, varied in duration from one day to three years, and recruited participants with mild or intermittent asthma, often with comorbid allergic rhinitis. Twenty-three studies recruited adults and teenagers; 31 recruited only children; three recruited both; and nine did not specify. The pattern of reporting and results remained largely unchanged from the original review despite 14 further studies and a 50% increase in participants studied (5077 to 7944). Reporting of primary efficacy outcomes to measure the impact of SLIT on asthma exacerbations and quality of life was infrequent, and selective reporting may have had a serious effect on the completeness of the evidence; 16 studies did not contribute any data, and a further six studies could only be included in a post hoc analysis of all adverse events. Allocation procedures were generally not well described; about a quarter of the studies were at high risk of performance or detection bias (or both); and participant attrition was high or unknown in around half of the studies. The primary outcome in most studies did not align with those of interest to the review (mostly asthma or rhinitis symptoms), and only two small studies reported our primary outcome of exacerbations requiring an ED or hospital visit; the pooled estimate from these studies suggests SLIT may reduce exacerbations compared with placebo or usual care, but the evidence is very uncertain (OR 0.35, 95% confidence interval (CI) 0.10 to 1.20; n = 108; very low-certainty evidence). Nine studies reporting quality of life could not be combined in a meta-analysis and, whilst the direction of effect mostly favoured SLIT, the effects were often uncertain and small. SLIT likely does not increase SAEs compared with placebo or usual care, and analysis by risk difference suggests no more than 1 in 100 people taking SLIT will have a serious adverse event (RD -0.0004, 95% CI -0.0072 to 0.0064; participants = 4810; studies = 29; moderate-certainty evidence). Regarding secondary outcomes, asthma symptom and medication scores were mostly measured with non-validated scales, which precluded meaningful meta-analysis or interpretation, but there was a general trend of SLIT benefit over placebo. Changes in ICS use (MD -17.13 µg/d, 95% CI -61.19 to 26.93; low-certainty evidence), exacerbations requiring oral steroids (studies = 2; no events), and bronchial provocation (SMD 0.99, 95% CI 0.17 to 1.82; low-certainty evidence) were not often reported. Results were imprecise and included the possibility of important benefit or little effect and, in some cases, potential harm from SLIT. More people taking SLIT had adverse events of any kind compared with control (OR 1.99, 95% CI 1.49 to 2.67; high-certainty evidence; participants = 4251; studies = 27), but events were usually reported to be transient and mild. Lack of data prevented most of the planned subgroup and sensitivity analyses.
AUTHORS' CONCLUSIONS
Despite continued study in the field, the evidence for important outcomes such as exacerbations and quality of life remains too limited to draw clinically useful conclusions about the efficacy of SLIT for people with asthma. Trials mostly recruited mixed populations with mild and intermittent asthma and/or rhinitis and focused on non-validated symptom and medication scores. The review findings suggest that SLIT may be a safe option for people with well-controlled mild-to-moderate asthma and rhinitis who are likely to be at low risk of serious harm, but the role of SLIT for people with uncontrolled asthma requires further evaluation.
Topics: Adolescent; Adult; Animals; Asthma; Child; Disease Progression; Hospitalization; Humans; Placebos; Pollen; Pyroglyphidae; Quality of Life; Randomized Controlled Trials as Topic; Rhinitis, Allergic; Sublingual Immunotherapy
PubMed: 32926419
DOI: 10.1002/14651858.CD011293.pub3 -
Chemosphere Dec 2023In recent years, the indoor exposure of organophosphate esters (OPEs) and novel brominated flame retardants (NBFRs) has received widespread attention worldwide. Using... (Review)
Review
Organophosphate esters (OPEs) and novel brominated flame retardants (NBFRs) in indoor dust: A systematic review on concentration, spatial distribution, sources, and human exposure.
In recent years, the indoor exposure of organophosphate esters (OPEs) and novel brominated flame retardants (NBFRs) has received widespread attention worldwide. Using published data on 6 OPEs in 23 countries (n = 1437) and 2 NBFRs in 18 countries (n = 826) in indoor dust, this study systematically reviewed the concentrations, spatial distribution, sources and exposure risk of 8 flame retardants (FRs) worldwide. Tris(chloroisopropyl)phosphate (TCIPP) is the predominant FR with a median concentration of 1050 ng g ΣCl-OPEs are significantly higher than Σnon-Cl-OPEs (p < 0.05). ΣOPEs in indoor dust from industrially-developed countries are higher than those from the countries lacking industrial development. Household appliances, electronics and plastic products are the main sources of non-Cl-OPEs and NBFRs, while interior decorations and materials contribute abundant Cl-OPEs in indoor dust. The mean hazard index (HI) of TCIPP for children is greater than 1, possibly posing non-cancer risk for children in some countries. The median ILCRs for 3 carcinogenic OPEs are all less than 10, suggesting no cancer risk induced by these compounds for both adults and children. This review helps to understand the composition, spatial pattern and human exposure risk of OPEs and NBFRs in indoor dust worldwide.
Topics: Child; Adult; Humans; Environmental Monitoring; Flame Retardants; Dust; Air Pollution, Indoor; Organophosphates; Esters; Environmental Exposure
PubMed: 37898464
DOI: 10.1016/j.chemosphere.2023.140560 -
Environmental Science and Pollution... Dec 2022Global prevalence trend and regional differences of coal worker's pneumoconiosis (CWP) remain unclear. This study aimed to provide systematic and comprehensive evidence... (Meta-Analysis)
Meta-Analysis
Global prevalence trend and regional differences of coal worker's pneumoconiosis (CWP) remain unclear. This study aimed to provide systematic and comprehensive evidence for the global prevalence of CWP. Literature research for studies that reported prevalence of CWP was conducted in PubMed, CNKI, and Web of Science. The identified studies were strictly screened according to predetermined inclusion and exclusion criteria. The pooled prevalence of CWP in different periods and regions was calculated. A total of 37 studies were included after screening, and data from the Coal Workers' Health Surveillance Program was additionally included in the meta-analysis. The global pooled prevalence of CWP decreased from 23.33% (95% confidence interval [CI]: 18.03%, 28.62%) before 1970 to 6.00% (95% CI: 4.11%, 7.90%) in 1981-1990, but indicated a rebound (10.35%, 95% CI: 8.08%, 12.62%) in 1991-2000 and finally dropped to 2.29% (95% CI: 2.06%, 2.51%) in 2011-2020. In the recent 30 years, the top three pooled prevalence of CWP was found in Europe, China, and the USA, respectively. Few articles have reported the prevalence in developing regions, but available evidence indicated that the prevalence in developing regions was much higher than that in developed regions. Higher pooled prevalence was observed in studies which reported larger number of miners in collieries, older average age of miners, underground collieries, and longer dust exposure time. The global prevalence of CWP indicates a rebound in 1990s, but the overall trend is downward in the recent 60 years. The prevention and treatment of CWP should be currently emphasized in developing countries.
Topics: Humans; Coal Mining; Prevalence; Anthracosis; Miners; Coal
PubMed: 35836046
DOI: 10.1007/s11356-022-21966-5 -
Cureus Apr 2023Musculoskeletal disorders (MSDs) are a substantial societal burden and various factors affect their causation, recovery, and prognosis. Management of MSDs is complex and... (Review)
Review
Musculoskeletal disorders (MSDs) are a substantial societal burden and various factors affect their causation, recovery, and prognosis. Management of MSDs is complex and requires multifaceted interventions. Given the challenges of MSDs and their continued burden, it is possible that additional elements could impact these disorders that have not been fully researched, for example, indoor environmental quality. Our previous review provided preliminary evidence that healthy building determinants (HBDs) are associated with the risk of back and neck pain. However, the relationship of HBDs with extremity MSDs and general MSDs (i.e., MSDs involving multiple body regions or in which body regions were unspecified in the original reports) has not been formally studied. The purpose of this review was to conduct a systematic literature review to assess the relationship of HBDs with extremity and general MSDs (PROSPERO ID: CRD42022314832). PubMed, CINAHL, Embase, and PEDRo databases were searched through April 2022. Inclusion criteria for study eligibility were as follows: humans of ages ≥18 years, reported on one or more of eight HBDs (1. air quality and ventilation, 2. dust and pests, 3. lighting and views, 4. moisture, 5. noise, 6. safety and security, 7. thermal health, 8. water quality), and compared these HBDs with extremity MSDs or general MSDs, original research, English. Exclusion criteria were as follows: articles not published in peer-reviewed journals, full-text articles unavailable. Review procedures were conducted and reported in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) recommendations. Empirical evidence statements were developed for 33 pairwise comparisons of HBDs with MSDs. The search uncovered 53 eligible studies with 178,532 participants. A total of 74.6% (39/53) of the studies were cross-sectional and 81.1% (43/53) were fair quality. Overall, the majority of uncovered evidence indicates that HBDs are related to risk of extremity and general MSDs. Nineteen comparisons support that as HBDs worsen, the risk of MSDs increases. Six comparisons had conflicting evidence. Three comparisons support that poor HBDs are not related to increased risk of extremity and general MSDs. Five comparisons had no evidence. This systematic review builds upon previous work to provide useful starting points to enhance awareness about the HBD-MSD relationship. These findings can help inform research and public health efforts aimed at addressing suboptimal HBDs through appropriate interventions to improve the lives of those suffering from MSDs.
PubMed: 37091490
DOI: 10.7759/cureus.37456