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Psychological Research Nov 2022This video is a proof of concept that ideas from embodied cognition can be used to understand how the brain and cognitive systems deal with very abstract concepts. The...
This video is a proof of concept that ideas from embodied cognition can be used to understand how the brain and cognitive systems deal with very abstract concepts. The video teaches regression to the mean using three ideas. The first idea is directly related to embodied cognition: abstract concepts are grounded in perceptual, motor, and emotional systems by using successive levels of grounding within an extended procedure. The second idea is that this sort of grounding often requires formal instruction: a teacher needs to develop the sequence in which the concepts are grounded and the methods of grounding. That is, at least some abstract concepts are unlikely to be learned through an individual's unstructured interactions with the world. The third idea is that humans are hyper-social, thus making formal instruction possible. To the extent that the viewer learns the abstract concept of regression to the mean, then the video demonstrates how an embodied theory of abstract concepts could work.
Topics: Humans; Concept Formation; Learning; Cognition; Brain; Emotions
PubMed: 34468857
DOI: 10.1007/s00426-021-01576-5 -
BMJ (Clinical Research Ed.) May 2024To determine the efficacy of psilocybin as an antidepressant compared with placebo or non-psychoactive drugs. (Meta-Analysis)
Meta-Analysis
OBJECTIVE
To determine the efficacy of psilocybin as an antidepressant compared with placebo or non-psychoactive drugs.
DESIGN
Systematic review and meta-analysis.
DATA SOURCES
Five electronic databases of published literature (Cochrane Central Register of Controlled Trials, Medline, Embase, Science Citation Index and Conference Proceedings Citation Index, and PsycInfo) and four databases of unpublished and international literature (ClinicalTrials.gov, WHO International Clinical Trials Registry Platform, ProQuest Dissertations and Theses Global, and PsycEXTRA), and handsearching of reference lists, conference proceedings, and abstracts.
DATA SYNTHESIS AND STUDY QUALITY
Information on potential treatment effect moderators was extracted, including depression type (primary or secondary), previous use of psychedelics, psilocybin dosage, type of outcome measure (clinician rated or self-reported), and personal characteristics (eg, age, sex). Data were synthesised using a random effects meta-analysis model, and observed heterogeneity and the effect of covariates were investigated with subgroup analyses and metaregression. Hedges' g was used as a measure of treatment effect size, to account for small sample effects and substantial differences between the included studies' sample sizes. Study quality was appraised using Cochrane's Risk of Bias 2 tool, and the quality of the aggregated evidence was evaluated using GRADE guidelines.
ELIGIBILITY CRITERIA
Randomised trials in which psilocybin was administered as a standalone treatment for adults with clinically significant symptoms of depression and change in symptoms was measured using a validated clinician rated or self-report scale. Studies with directive psychotherapy were included if the psychotherapeutic component was present in both experimental and control conditions. Participants with depression regardless of comorbidities (eg, cancer) were eligible.
RESULTS
Meta-analysis on 436 participants (228 female participants), average age 36-60 years, from seven of the nine included studies showed a significant benefit of psilocybin (Hedges' g=1.64, 95% confidence interval (CI) 0.55 to 2.73, P<0.001) on change in depression scores compared with comparator treatment. Subgroup analyses and metaregressions indicated that having secondary depression (Hedges' g=3.25, 95% CI 0.97 to 5.53), being assessed with self-report depression scales such as the Beck depression inventory (3.25, 0.97 to 5.53), and older age and previous use of psychedelics (metaregression coefficient 0.16, 95% CI 0.08 to 0.24 and 4.2, 1.5 to 6.9, respectively) were correlated with greater improvements in symptoms. All studies had a low risk of bias, but the change from baseline metric was associated with high heterogeneity and a statistically significant risk of small study bias, resulting in a low certainty of evidence rating.
CONCLUSION
Treatment effects of psilocybin were significantly larger among patients with secondary depression, when self-report scales were used to measure symptoms of depression, and when participants had previously used psychedelics. Further research is thus required to delineate the influence of expectancy effects, moderating factors, and treatment delivery on the efficacy of psilocybin as an antidepressant.
SYSTEMATIC REVIEW REGISTRATION
PROSPERO CRD42023388065.
Topics: Humans; Antidepressive Agents; Depression; Hallucinogens; Psilocybin; Randomized Controlled Trials as Topic; Treatment Outcome
PubMed: 38692686
DOI: 10.1136/bmj-2023-078084 -
Developmental Science May 2021Social interactions provide a crucial context for early learning and cognitive development during infancy. Action prediction-the ability to anticipate an observed...
Social interactions provide a crucial context for early learning and cognitive development during infancy. Action prediction-the ability to anticipate an observed action-facilitates successful, coordinated interaction and is an important social-cognitive skill in early development. However, current knowledge about infant action prediction comes largely from screen-based laboratory tasks. We know little about what infants' action prediction skills look like during real-time, free-flowing interactions with a social partner. In the current study, we used head-mounted eyetracking to quantify 9-month-old infants' visual anticipations of their parents' actions during free-flowing parent-child play. Our findings reveal that infants do anticipate their parents' actions during dynamic interactions at rates significantly higher than would be expected by chance. In addition, the frequency with which they do so is associated with child-led joint attention and hand-eye coordination. These findings are the first to reveal infants' action prediction behaviors in a more naturalistic context than prior screen-based studies, and they support the idea that action prediction is inherently linked to motor development and plays an important role in infants' social-cognitive development. A video abstract of this article can be viewed at https://www.youtube.com/watch?v=9HrmcicfiqE.
Topics: Attention; Child; Child Development; Cognition; Humans; Infant; Learning; Parents
PubMed: 33030770
DOI: 10.1111/desc.13042 -
Rehabilitacion 2023Since 2020 we have lived an exceptional situation that made us experience a complete lockdown due to SARS-CoV-2, what affected the treatments of different pathologies,... (Review)
Review
Since 2020 we have lived an exceptional situation that made us experience a complete lockdown due to SARS-CoV-2, what affected the treatments of different pathologies, such as the chronic obstructive pulmonary disease (COPD). Because of those reasons, it has arisen the idea of implementing the tele-rehabilitation program as a treatment of these pathologies. The search was done between the months of October and November 2020, with the aim of analyzing and updating the efficacy of the tele-rehabilitation in patients who have COPD, finding eight articles which met the inclusion criteria. The pulmonary tele-rehabilitation is able to improve the quality of life and physical state, and decreasing the number of hospitalizations and exacerbations. Furthermore, patients showed a great level of satisfaction and adherence to this treatment program. The pulmonary tele-rehabilitation can achieve similar results as of pulmonary rehabilitation. For this reason, people who have difficulties to go to their outpatients clinic or even in a lockdown can use it. However, it is necessary to investigate which tele-rehabilitation program is better.
Topics: Humans; Telerehabilitation; Quality of Life; Pulmonary Disease, Chronic Obstructive; Hospitalization
PubMed: 37329647
DOI: 10.1016/j.rh.2022.100781 -
Social Studies of Science Aug 2022This article maps the rise and fall of the idea of a (social) group across medicine in the context of contemporary analyses in psychology and sociology. This history...
This article maps the rise and fall of the idea of a (social) group across medicine in the context of contemporary analyses in psychology and sociology. This history shows the early 20th century emergence and growth of group medicine, group therapy and group comparisons. In recent decades, however, the idea that groups constituted the basic units of society has been replaced with the emergence of populations and systems that offer a more virtual and abstract context for individual relationships. This has implications for explanation itself as the demise of groups has changed the epistemological ground-rules for understanding identity formation and social change.
Topics: History, 20th Century; Knowledge; Social Change; Sociology
PubMed: 35635027
DOI: 10.1177/03063127221096389 -
PloS One 2022The rapid development of modern science nowadays makes it rather challenging to pick out valuable ideas from massive scientific literature. Existing widely-adopted...
The rapid development of modern science nowadays makes it rather challenging to pick out valuable ideas from massive scientific literature. Existing widely-adopted citation-based metrics are not adequate for measuring how well the idea presented by a single publication is developed and whether it is worth following. Here, inspired by traditional X-ray imaging, which returns internal structure imaging of real objects along with corresponding structure analysis, we propose Scientific X-ray, a framework that quantifies the development degree and development potential for any scientific idea through an assembly of 'X-ray' scanning, visualization and parsing operated on the citation network associated with a target publication. We pick all 71,431 scientific articles of citation counts over 1,000 as high-impact target publications among totally 204,664,199 publications that cover 16 disciplines spanning from 1800 to 2021. Our proposed Scientific X-ray reproduces how an idea evolves from the very original target publication all the way to the up to date status via an extracted 'idea tree' that attempts to preserve the most representative idea flow structure underneath each citation network. Interestingly, we observe that while the citation counts of publications may increase unlimitedly, the maximum valid idea inheritance of those target publications, i.e., the valid depth of the idea tree, cannot exceed a limit of six hops, and the idea evolution structure of any arbitrary publication unexceptionally falls into six fixed patterns. Combined with a development potential index that we further design based on the extracted idea tree, Scientific X-ray can vividly tell how further a given idea presented by a given publication can still go from any well-established starting point. Scientific X-ray successfully identifies 40 out of 49 topics of Nobel prize as high-potential topics by their prize-winning papers in an average of nine years before the prizes are released. Various trials on articles of diverse topics also confirm the power of Scientific X-ray in digging out influential/promising ideas. Scientific X-ray is user-friendly to researchers with any level of expertise, thus providing important basis for grasping research trends, helping scientific policy-making and even promoting social development.
Topics: Abstracting and Indexing; Publications
PubMed: 36170296
DOI: 10.1371/journal.pone.0275192 -
Nederlands Tijdschrift Voor Geneeskunde Jun 2023The quality of communication influences the patient-doctor relationship. Patient satisfaction and compliance improve when a healthcare professional shows empathy and... (Review)
Review
The quality of communication influences the patient-doctor relationship. Patient satisfaction and compliance improve when a healthcare professional shows empathy and compassion. A substantial part of communication is non-verbal, especially in more complex conversations. A physician's physical posture during interaction with the patient is therefore crucial. Although sitting at the bedside is considered as best practice, we increasingly tend to stand during bedside interactions. This might be caused by time constraints and the idea that sitting down may be more time consuming. In this article we discuss the importance of posture. The psychological background of certain body language is reviewed. In addition, we give a concise review of the literature which shows that patient outcomes such as satisfaction are better in a sitting interactions, and that this interaction is not more time consuming.
Topics: Humans; Patients; Physician-Patient Relations; Empathy; Communication; Posture
PubMed: 37345619
DOI: No ID Found -
Pakistan Journal of Medical Sciences 2023Simulation-based learning has been a part of teaching in healthcare for a long time; however, in recent decades, simulation-based learning has been adopted by a... (Review)
Review
BACKGROUND AND OBJECTIVE
Simulation-based learning has been a part of teaching in healthcare for a long time; however, in recent decades, simulation-based learning has been adopted by a significant number of healthcare institutes at different levels to improve practical skills, confidence, and preparedness to ensure patient safety and its application in real-life situations towards better patient care. The main objective of this paper was to use existing literature to explore aspects of simulation in healthcare teaching.
METHODS
It is a narrative review on simulation in healthcare that was conducted by using various search engines for English-language articles published between 2010 and August 2020. The main search terms were simulation, healthcare teaching, and simulation in healthcare. All articles found relevant to the title and/or abstract were retrieved. Searches were conducted using the academic databases PubMed, Google Scholar, MEDLINE, CINAHL, and Athabasca University (AU) library site. The studies were reviewed if they were considered relevant to the search by the primary authors.
RESULTS
Thirty-nine articles, which met the pre-set criteria, were analyzed and employed as a reference in this paper to support the idea that simulation is an effective way of learning in healthcare.
CONCLUSION
This paper reviewed various aspects of simulation, including its background, philosophies, and highlighted the advantages and disadvantages of incorporating simulation as a pedagogical approach into current educational curriculums for healthcare students. Furthermore, it presents a brief discussion on the current uses of simulation, followed by the educational strategies related to simulation and the importance of debriefing in simulation activities.
PubMed: 37492303
DOI: 10.12669/pjms.39.4.7145 -
Zhonghua Shao Shang Yu Chuang Mian Xiu... Oct 2022Burns often cause the damaged tissue to produce a large amount of exudate and the formation of blisters on the wound. The burn blister fluid contains a large number of...
Burns often cause the damaged tissue to produce a large amount of exudate and the formation of blisters on the wound. The burn blister fluid contains a large number of molecules related to wound healing, which can reflect the state of local tissue microenvironment of the burn wound. Analyzing relevant information such as cellular components, signal mediators, and protein molecules in burn blister fluid is helpful to understand the local reaction and tissue microenvironment of burn wounds, and then help clinical burn treatment. In this article, by understanding the production mechanism of burn blister fluid, discussing its role in wound evaluation, and integrating the research progress of burn blister fluid in proteomics, metabolomics, cellular components, and pharmacokinetics, we propose our thoughts and prospects on the research of burn blister fluid, in order to provide assistance for clinical evaluation and treatment of burn wounds, and also provide idea for the follow-up study of burn blister fluid.
Topics: Humans; Blister; Follow-Up Studies; Burns; Exudates and Transudates; Wound Healing
PubMed: 36299215
DOI: 10.3760/cma.j.cn501120-20211109-00380 -
Revista Medica Del Instituto Mexicano... Sep 2023The World Kidney Day was founded in 2003 by doctor Joel D. Kopple, American nephrologist, who in the session in the Congress of the International Federation of Kidney...
The World Kidney Day was founded in 2003 by doctor Joel D. Kopple, American nephrologist, who in the session in the Congress of the International Federation of Kidney Foundations explained the need to implement the celebration on a day that alludes to this organ, in order to direct preventive actions for kidney disease and raise awareness in the medical community and the general population on the importance of caring for the kidneys. 3 years later, the proposal was accepted and as of 2006 World Kidney Day is celebrated. The diffusion is found throughout the world and in each place there are talks, courses, workshops, cultural activities and even marathons related to the prevention, diagnosis and treatment of kidney disease. Chronic kidney disease (CKD) is a disorder with a chronic, degenerative, and lethal evolution. Managing CKD requires a large amount of human, financial, and infrastructure resources. It impairs the quality of life and negatively affects survival. On the other hand, it leads to dialysis and kidney transplant treatments, which are expensive enough to put any health institution at financial risk, especially those most vulnerable. The main idea of these non-profit international organizations is to promote the well-being and improve the quality of life of people with CKD with and without dialysis, and to promote kidney transplantation as the first treatment option.
Topics: Humans; Quality of Life; Kidney; Renal Insufficiency, Chronic; Kidney Transplantation; Renal Dialysis
PubMed: 37769134
DOI: 10.5281/zenodo.8316457