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JPMA. the Journal of the Pakistan... Feb 2021To explore relationship involving Ego Defence Mechanism, Medication Adherence and Self-Management of patients with type 2 diabetes.
OBJECTIVE
To explore relationship involving Ego Defence Mechanism, Medication Adherence and Self-Management of patients with type 2 diabetes.
METHODS
The cross-sectional co-relational study was conducted at the Government College University, Lahore, Pakistan, from November 2017 to November 2018, and comprised diabetics aged 25-55 years. Other than demographic information, data was collected using the Urdu versions of the Defense Style Questionnaire, the Medication Adherence Scale, and the Diabetic Self-management Questionnaire. Data was analysed using SPSS 22.
RESULTS
Of the 150 patients, 75(50%) each were females and males. Mature defence mechanisms, like sublimation, suppression and humour, were significant predictors of self-management (p<0.001), and mature defence mechanism, like sublimation, was a significant predictor of medication adherence (p<0.05). Females were high on neurotic defence mechanism, like pseudo-altruism, compared to the males (p=0.001).
CONCLUSIONS
Medication adherence and self-management were found to be dependent on mature defence mechanisms.
Topics: Adult; Cross-Sectional Studies; Defense Mechanisms; Diabetes Mellitus, Type 2; Ego; Female; Humans; Male; Medication Adherence; Middle Aged; Pakistan; Self-Management; Surveys and Questionnaires
PubMed: 33941947
DOI: 10.47391/JPMA.706 -
Psychological Reports Oct 2023The notion of psychological androgyny as a research tool loiters on in an incapacitated state. The lack of a general theory and the belief that the biological gender... (Review)
Review
The notion of psychological androgyny as a research tool loiters on in an incapacitated state. The lack of a general theory and the belief that the biological gender differences are insignificant to non-existent has been the seeds for its de-construction. Over the decades, the testing of ideas associated with androgyny has declined. Indeed, the debates over its usefulness as a construct ended long ago. The judgment nowadays is that debating the constructs of masculinity, femininity, and androgyny as behavioral traits has been long settled, and a contemporary revisiting of androgyny is not warranted. However, from another contemporary viewpoint, if androgyny is to have any future, it needs a new theory devoid of masculinity and femininity. We present a novel theory with the potential to do just that. This article details a new de-gendered theory of psychological androgyny, neo-androgyny, as a candidate to replace traditional models that are now considered outdated and irrelevant. We present five potential factors for inclusion in a de-gendered model: social efficacy, creativity, capability, eminence, and determination. We review these factors concerning the future of androgyny theory.
Topics: Male; Female; Humans; Gender Identity; Masculinity; Creativity; Sex Factors
PubMed: 35343328
DOI: 10.1177/00332941221076759 -
Journal of Personality Disorders Jun 2020In schema therapy, modes are proposed as a key concept and main target for treatment of personality disorders. The present study aimed to assess a comprehensive set of...
In schema therapy, modes are proposed as a key concept and main target for treatment of personality disorders. The present study aimed to assess a comprehensive set of 20 modes, to explore their higher-order structure, and to link the mode factors to the generic schema factor and basic personality traits. The sample consisted of N = 533 inpatients. Earlier versions of the Schema Mode Inventory (SMI, SMI-2) were merged into the German Extended SMI (GE-SMI). Item-level confirmatory factor analyses indicated that the structure of 16 out of 20 GE-SMI scales might be unidimensional. Scale-level exploratory factor analysis revealed three hierarchically structured mode factors: internalization, externalization, and compulsivity. Regressing mode factor scores on the Big Five factors and the generic schema factor supported the validity of the mode factors. The hierarchical structure of modes will be linked to the Hierarchical Taxonomy of Psychopathology, and implications for case conceptualization and treatment will be discussed.
Topics: Adaptation, Psychological; Concept Formation; Defense Mechanisms; Diagnostic and Statistical Manual of Mental Disorders; Factor Analysis, Statistical; Humans; Inpatients; Male; Personality Disorders; Psychopathology
PubMed: 30307830
DOI: 10.1521/pedi_2018_32_401 -
Psychological Reports Feb 2022The main objective of the study is to explore relations between the time perspective, neurotic symptoms, anxiety, and defense mechanisms in the group of patients...
Time in the Mental Health Context: Neurotic Symptomatology, Defense Mechanisms and the Perception of Time Perspective Among Patients Diagnosed With Neurotic and Personality Disorders - A Clinical Study.
AIM
The main objective of the study is to explore relations between the time perspective, neurotic symptoms, anxiety, and defense mechanisms in the group of patients diagnosed with neurotic and personality disorders (ICD-10 groups: F4x, F60.x and F61) treated with group psychotherapy. The research is conducted on the theoretical basis of the Zimbardo and Boyd's Time Perspective Theory.
METHODS
The study included 49 patients treated in the day ward for the Treatment of Neurotic Disorders and Behavioral Syndromes at the University Hospital. The measurement of the TP was performed with the Zimbardo Time Perspective Inventory. Patients also completed the State-Trait Anxiety Inventory and the Defense Style Questionnaire 40. The diagnosis was done by licensed psychiatrists and supported with the measures: Symptom Checklist KO"O", Neurotic Personality Questionnaire KON-2006.
RESULTS
Multiple regression analysis models showed that the four time perspectives (past negative, present fatalistic, present hedonistic, and future) are predicted in different variations by the level of anxiety state or trait and repertoire of used defense mechanisms (immature or mature).
CONCLUSIONS
Considering the established bilateral correlations, change in the time perspective may constitute an important factor in the reduction of neurotic symptoms, possibly through changes in the repertoire of utilized defense mechanisms. However, there is also possible that altering neurotic symptomatology would alter time perspective. The assessment of the time perspective in patients with neurotic and personality disorders may provide useful data for the diagnosis and the monitoring of psychotherapy effectiveness. Based on the results of this study conducting further research on the role of the changes in the time perspective in the course of psychotherapy is recommended and necessary to expand the understanding of the relations observed in this study.
Topics: Defense Mechanisms; Humans; Mental Health; Personality Disorders; Time Perception; Treatment Outcome
PubMed: 33349168
DOI: 10.1177/0033294120978164 -
International Journal of Molecular... Jan 2024Plant-growth-promoting rhizobacteria (PGPR) could potentially enhance photosynthesis and benefit plant growth by improving soil nutrient uptake and affecting plant... (Review)
Review
Plant-growth-promoting rhizobacteria (PGPR) could potentially enhance photosynthesis and benefit plant growth by improving soil nutrient uptake and affecting plant hormone balance. Several recent studies have unveiled a correlation between alterations in photosynthesis and host plant resistance levels. Photosynthesis provides materials and energy for plant growth and immune defense and affects defense-related signaling pathways. Photosynthetic organelles, which could be strengthened by PGPR inoculation, are key centers for defense signal biosynthesis and transmission. Although endophytic PGPRs metabolize plant photosynthates, they can increase soluble sugar levels and alternate sugar type and distribution. Soluble sugars clearly support plant growth and can act as secondary messengers under stressed conditions. Overall, carbohydrate metabolism modifications induced by PGPR may also play a key role in improving plant resistance. We provide a concise overview of current knowledge regarding PGPR-induced modulation in carbohydrate metabolism under both pathogen-infected and pathogen-free conditions. We highlight PGPR application as a cost-saving strategy amidst unpredictable pathogen pressures.
Topics: Plant Development; Plant Growth Regulators; Carbohydrate Metabolism; Alphaproteobacteria; Sugars; Defense Mechanisms
PubMed: 38338742
DOI: 10.3390/ijms25031465 -
Microbiology Spectrum Mar 2023Phages and bacteria have acquired resistance mechanisms for protection. In this context, the aims of the present study were to analyze the proteins isolated from 21...
Phages and bacteria have acquired resistance mechanisms for protection. In this context, the aims of the present study were to analyze the proteins isolated from 21 novel lytic phages of Klebsiella pneumoniae in search of defense mechanisms against bacteria and also to determine the infective capacity of the phages. A proteomic study was also conducted to investigate the defense mechanisms of two clinical isolates of K. pneumoniae infected by phages. For this purpose, the 21 lytic phages were sequenced and assembled. The host range was determined in a collection of 47 clinical isolates of K. pneumoniae, revealing the variable infective capacity of the phages. Genome sequencing showed that all of the phages were lytic phages belonging to the order s. Phage sequence analysis revealed that the proteins were organized in functional modules within the genome. Although most of the proteins have unknown functions, multiple proteins were associated with defense mechanisms against bacteria, including the restriction-modification system, the toxin-antitoxin system, evasion of DNA degradation, blocking of host restriction and modification, the orphan CRISPR-Cas system, and the anti-CRISPR system. Proteomic study of the phage-host interactions (i.e., between isolates K3574 and K3320, which have intact CRISPR-Cas systems, and phages vB_KpnS-VAC35 and vB_KpnM-VAC36, respectively) revealed the presence of several defense mechanisms against phage infection (prophage, defense/virulence/resistance, oxidative stress and plasmid proteins) in the bacteria, and of the Acr candidate (anti-CRISPR protein) in the phages. Researchers, including microbiologists and infectious disease specialists, require more knowledge about the interactions between phages and their bacterial hosts and about their defense mechanisms. In this study, we analyzed the molecular mechanisms of viral and bacterial defense in phages infecting clinical isolates of K. pneumoniae. Viral defense mechanisms included restriction-modification system evasion, the toxin-antitoxin (TA) system, DNA degradation evasion, blocking of host restriction and modification, and resistance to the abortive infection system, anti-CRISPR and CRISPR-Cas systems. Regarding bacterial defense mechanisms, proteomic analysis revealed expression of proteins involved in the prophage (FtsH protease modulator), plasmid (cupin phosphomannose isomerase protein), defense/virulence/resistance (porins, efflux pumps, lipopolysaccharide, pilus elements, quorum network proteins, TA systems, and methyltransferases), oxidative stress mechanisms, and Acr candidates (anti-CRISPR protein). The findings reveal some important molecular mechanisms involved in the phage-host bacterial interactions; however, further study in this field is required to improve the efficacy of phage therapy.
PubMed: 36877024
DOI: 10.1128/spectrum.03974-22 -
Journal of Applied Genetics Feb 2021Various strategies have been developed globally to conserve germplasm by propagating plants. One important technique is in vitro propagation and preservation through...
Old Catharanthus roseus culture (14 years) produced somatic embryos and plants and showed normal genome size; demonstrated an increased antioxidant defense mechanism; and synthesized stress proteins as biochemical, proteomics, and flow-cytometry studies reveal.
Various strategies have been developed globally to conserve germplasm by propagating plants. One important technique is in vitro propagation and preservation through tissue culture. In many investigated plants, the long in vitro conservation is plagued with several limitations like genetic variations, developmental errors in cells or tissues due to induced stress. This provoked us to conduct a study of Catharanthus roseus culture maintained for over fourteen long years and a newly established 8-month-old culture. The present study investigated and compared the two tissue types differing by their age. The biomass accumulation, the biochemical differences of the two, dead cell analysis with aging via confocal microscopy, and liquid chromatography-mass spectroscopy (LC-MS)-based proteomic differences were studied in old and newly established Catharanthus culture. The proteomic study reveals more than 120 upregulated or high abundance proteins in old culture as compared to newly established Catharanthus. The identified upregulated proteins are stress protein 69, heat shock proteins (HSP), isocitrate dehydrogenase, pyruvate dehydrogenase, and others. These proteins had an association with antioxidant activities, related to stress, and a few are linked to respiration. Our study reveals the presence of a robust antioxidant defense mechanism, i.e., 51.94%, 78.8%, and 61% higher SOD, APX, and CAT activities in older cultures (O) as compared to newly established tissues (N), which perhaps act against stress and may play a key role in ameliorating negative impacts of long-term in vitro conditions. The inherent strong antioxidant defense system in old cultures added resilience and enabled the culture to revive growth quickly (within 1-2 days) following transfer to new medium as compared to new culture (7-10 days). The biomass accumulation was more (37.08 %) in old tissues as compared to new culture. The 2C DNA or genome size of C. roseus especially the 14-year-old culture-derived regenerated plant was measured by flow cytometry. The 2C DNA size of this Catharanthus (old culture) plant is 1.516 pg, which is very similar to new culture-derived plants' and field-grown plants' genome size. No anomaly in genome size was noted in plants of old culture, as opposed to common perception.
Topics: Antioxidants; Catharanthus; Defense Mechanisms; Genome Size; Genome, Plant; Heat-Shock Proteins; Plant Proteins; Proteomics
PubMed: 33145639
DOI: 10.1007/s13353-020-00590-4 -
Journal of Interpersonal Violence Nov 2020In the current study, we aim to examine the link between exposure to multiple traumatic events (polyvictimization), posttraumatic stress disorder (PTSD) symptoms (PTSS),...
In the current study, we aim to examine the link between exposure to multiple traumatic events (polyvictimization), posttraumatic stress disorder (PTSD) symptoms (PTSS), and psychiatric symptomatology in early adolescence. Furthermore, we aim to explore the mediating roles of defense styles and coping styles in the associations between polyvictimization, PTSS, and psychiatric symptomatology. Data from a Danish national representative sample of 390 eighth-grade students with a mean age of 13.95 ( = 0.37) years were used. Participants responded to validated self-report questionnaires in 2001. The dimensions of immature defense styles and emotional and avoidance coping mediated the positive associations between polyvictimization, PTSS, and psychiatric symptomatology. Serial multiple mediation indicated that the sum of exposure to traumatic events was significantly associated with more immature defense styles, associated with both high levels emotional and avoidance coping, which, in turn, were associated with high levels of PTSS and psychiatric symptomatology. Polyvictimization is related to adverse outcomes in early adolescence. Both immature defense styles and emotional and avoidance coping styles should be considered as risk factors for the development of psychological distress following exposure to multiple traumas.
Topics: Adaptation, Psychological; Adolescent; Defense Mechanisms; Emotions; Female; Humans; Life Change Events; Male; Psychological Distress; Resilience, Psychological; Stress Disorders, Post-Traumatic; Surveys and Questionnaires
PubMed: 29294815
DOI: 10.1177/0886260517716944 -
Journal of Health Care Chaplaincy 2023Spiritual support has been a staple of healthcare before hospitals in western civilizations were established by communities of faith. Research has demonstrated that... (Review)
Review
Spiritual support has been a staple of healthcare before hospitals in western civilizations were established by communities of faith. Research has demonstrated that wellbeing is associated with balanced care for the body, mind, and spirit. Healthcare disparities are being identified as disproportionally impacting transgender and gender nonconforming (TGNC) individuals. The root cause of this disparity is being studied as are medical and wellbeing interventions, including the benefit of spiritual support. This author's objective was two-fold. First, to identify opportunities for extending spiritual support to TGNC individuals in healthcare by chaplains. Secondly, to identify evidence of current spiritual support advocacy initiatives and interventions for TGNC patients in healthcare by chaplains.
Topics: Humans; Transgender Persons; Transsexualism; Gender Identity; Healthcare Disparities
PubMed: 35776733
DOI: 10.1080/08854726.2022.2080965 -
Turk Psikiyatri Dergisi = Turkish... 2022This study aims to investigate the relationship between suicide possibilities, defense mechanisms, and eating awareness of patients who have undergone bariatric surgery.
OBJECTIVE
This study aims to investigate the relationship between suicide possibilities, defense mechanisms, and eating awareness of patients who have undergone bariatric surgery.
METHOD
The study sample consisted of 101 patients who had bariatric surgery in a private hospital. People who had at least six months from the date of surgery, who had no pregnancy, and who did not give birth after surgery were included in the study. The Mindful Eating Questionnaire, Suicide Probability Scale, and the Defense Style Questionnaire were applied to the participants.
RESULTS
While the average age of the sample was 52.46±9.72, 54.5% (n=55) were male. Within one year after the operation, 33.7% of (n=34) patients had lost weight between 21-30 kg, while 21.8% (n=22) had lost weight between 11-20 kg. Suicide probability scale scores are predicted by emotional eating (β=0.272, p=0.004), neurotic defense mechanism (β=0.284, p=0.003) and current body mass index (β=0.258, p=0.008).
CONCLUSION
The possibility of suicide after bariatric surgery is closely related to emotional eating, neurotic defense mechanisms, and body mass index. The solution to the problem of emotional eating rather than decreasing the body mass index may be more effective in decreasing the suicide possibilities of the patients. Therefore, in patients undergoing bariatric surgery, emotional eating is one of the problems that should be handled both before and after surgery.
Topics: Bariatric Surgery; Defense Mechanisms; Female; Humans; Male; Obesity; Probability; Suicide
PubMed: 36148568
DOI: 10.5080/u25891