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Journal of Neurointerventional Surgery Apr 2024
PubMed: 38653523
DOI: 10.1136/jnis-2024-021484 -
Annals of Internal Medicine Jun 2021Klompas and colleagues report an investigation of a SARS-CoV-2 cluster in an acute care hospital with transmission between patients and staff. The editorialists remind...
Klompas and colleagues report an investigation of a SARS-CoV-2 cluster in an acute care hospital with transmission between patients and staff. The editorialists remind us of the need to reinforce and reeducate to improve practice of and adherence to important strategies that protect the entire health care ecosystem.
Topics: COVID-19; Delivery of Health Care; Hospitals; Humans; SARS-CoV-2
PubMed: 33556269
DOI: 10.7326/M21-0526 -
Memory & Cognition Apr 2022I propose a model that places episodic, semantic, and other commonly studied forms of memory into the same conceptual space. The space is defined by three dimensions...
I propose a model that places episodic, semantic, and other commonly studied forms of memory into the same conceptual space. The space is defined by three dimensions required for Tulving's episodic and semantic memory. An implicit-explicit dimension contrasts both episodic and semantic memory with common forms of implicit memory. A self-reference dimension contrasts episodes that occurred to one person with semantic knowledge. A scene dimension contrasts episodes that occurred in specific contexts with context-free semantic information. The three dimensions are evaluated against existing behavioral and neural evidence to evaluate both the model and the concepts underlying the study of human memory. Unlike a hierarchy, which has properties specific to each category, the dimensions have properties that extend throughout the conceptual space. Thus, the properties apply to all forms of existing and yet-to-be-discovered memory within the space. Empty locations in the proposed space are filled with existing phenomena that lack a clear place in current theories of memory, including reports of episodic-like memories for events reported to but not witnessed by a person, fictional narrative accounts, déjà vu, and implicit components contributing to personality, the self, and autobiographical memory.
Topics: Humans; Memory, Episodic; Mental Recall; Semantics
PubMed: 33650021
DOI: 10.3758/s13421-021-01148-3 -
Annals of Internal Medicine Jun 2021
Topics: Community Participation; Firearms; Humans; Mass Casualty Incidents; Physician's Role; United States; Wounds, Gunshot
PubMed: 33793324
DOI: 10.7326/M21-1505 -
Clinical Infectious Diseases : An... Nov 2021
Topics: Antiviral Agents; Hepacivirus; Hepatitis C, Chronic; Humans; Retreatment
PubMed: 32887999
DOI: 10.1093/cid/ciaa1329 -
Journal of Neuroimmunology Sep 2021Herpesviruses like Epstein-Barr virus, human herpesvirus (HHV)-6, HHV-1, VZV, and human endogenous retroviruses, have an age-old clinical association with multiple... (Review)
Review
Herpesviruses like Epstein-Barr virus, human herpesvirus (HHV)-6, HHV-1, VZV, and human endogenous retroviruses, have an age-old clinical association with multiple sclerosis (MS). MS is an autoimmune disease of the nervous system wherein the myelin sheath deteriorates. The most popular mode of virus mediated immune system manipulation is molecular mimicry. Numerous herpesvirus antigens are similar to myelin proteins. Other mechanisms described here include the activity of cytokines and autoantibodies produced by the autoreactive T and B cells, respectively, viral déjà vu, epitope spreading, CD46 receptor engagement, impaired remyelination etc. Overall, this review addresses the host-parasite association of viruses with MS.
Topics: Autoantibodies; Herpesviridae; Herpesvirus 1, Human; Herpesvirus 3, Human; Herpesvirus 4, Human; Herpesvirus 6, Human; Humans; Multiple Sclerosis
PubMed: 34174587
DOI: 10.1016/j.jneuroim.2021.577636 -
Fertility and Sterility Dec 2019
Topics: Aneuploidy; Embryo Transfer; Genetic Testing; Humans; Patient Selection; Prognosis
PubMed: 31843076
DOI: 10.1016/j.fertnstert.2019.08.102 -
Epilepsy & Behavior : E&B Aug 2019Déjà vu (DV) is a fascinating and mysterious human experience that has attracted interest from psychologists and neuroscientists for over a century. In recent years,...
Déjà vu (DV) is a fascinating and mysterious human experience that has attracted interest from psychologists and neuroscientists for over a century. In recent years, several studies have been conducted to unravel the psychological and neurological correlates of this phenomenon. However, the neural mechanisms underlying the DV experience in benign manifestations are still poorly understood. Thirty-three healthy volunteers completed an extensive neuropsychiatric and neuropsychological battery including personality evaluation. The presence of DV was assessed with the Inventory for Deja vu Experiences Assessment. Participants underwent episodic memory learning test, and 2 days later during event-related functional magnetic resonance imaging (fMRI), they are asked to rate old and new pictures as a novel, moderately/very familiar, or recollected. We identified 18 subjects with DV (DV+) and 15 without DV (DV-) matched for demographical, neuropsychological, and personality characteristics. At a behavioral level, no significant difference was detected in the episodic memory tasks between DV+ and DV-. Functional magnetic resonance imaging analysis revealed that DV+, independently from task conditions, were characterized by increased activity of the bilateral insula coupled with reduced activation in the right parahippocampal, both hippocampi, superior/middle temporal gyri, thalami, caudate nuclei, and superior frontal gyri with respect to DV-. Our study demonstrates that individuals who experienced DV are not characterized by different performance underlying familiarity/recollection memory processes. However, fMRI results provide evidence that the physiological DV experience is associated with the employment of different neural responses of brain regions involved in memory and emotional processes.
Topics: Adult; Brain; Brain Mapping; Cognition; Deja Vu; Emotions; Female; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Memory; Memory, Episodic; Mental Recall; Prefrontal Cortex; Temporal Lobe
PubMed: 31181431
DOI: 10.1016/j.yebeh.2019.05.018 -
Drugs & Aging Sep 2021
Topics: Alzheimer Disease; Hormones; Humans
PubMed: 34342861
DOI: 10.1007/s40266-021-00887-x -
Memory (Hove, England) Aug 2021Jamais vu is a phenomenon operationalised as the opposite of déjà vu, i.e. finding subjectively unfamiliar something that we know to be familiar. We sought to document...
Jamais vu is a phenomenon operationalised as the opposite of déjà vu, i.e. finding subjectively unfamiliar something that we know to be familiar. We sought to document that the subjective experience of jamais vu can be produced in word alienation tasks, hypothesising that déjà vu and jamais vu are similar experiential memory phenomena. Participants repeatedly copied words until they felt "peculiar", had completed the task, or had another reason to stop. About two-thirds of all participants (in about one-third of all trials) reported strange subjective experiences during the task. Participants reported feeling peculiar after about thirty repetitions, or one minute. We describe these experiences as jamais vu. This experimentally induced phenomenon was related to real-world experiences of unfamiliarity. Although we replicated known patterns of correlations with déjà vu (age and dissociative experiences), the same pattern was not found for our experimental analogue of jamais vu, suggesting some differences between the two phenomena. However, in daily life, those people who had déjà vu more frequently also had jamais vu more frequently. Findings are discussed with reference to the progress that has been made in déjà vu research in recent years, with a view to fast-tracking our understanding of jamais vu.
Topics: Dissociative Disorders; Emotions; Humans; Laboratories; Satiation; Semantics
PubMed: 32079491
DOI: 10.1080/09658211.2020.1727519