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Clinical Oral Investigations Dec 2022The aim of the present in vitro study is to determine the cytocompatibility of the recently introduced NeoPutty in contact with human dental pulp cells compared with its...
OBJECTIVES
The aim of the present in vitro study is to determine the cytocompatibility of the recently introduced NeoPutty in contact with human dental pulp cells compared with its precursor NeoMTA Plus and the classic gold standard MTA Angelus.
MATERIALS AND METHODS
Sample disks were obtained for each of the tested materials (5 mm diameter; 2 mm thickness; n = 30), along with 1:1, 1:2, and 1:4 material eluents. HDPCs were extracted and cultured with the tested materials (test groups) or in unconditioned medium (control group), and the following biocompatibility assays were performed: MTT assay, scratch wound assay, cell cytoskeleton staining assays, and cell attachment assessment via SEM. Additionally, material ion release and surface element composition were evaluated via ICP-MS and SEM-EDX, respectively. Each experimental condition was carried out three times and assessed in three independent experiments. Statistical significance was established at p < 0.05.
RESULTS
1:2 dilutions of all the tested materials exhibited a comparable cell viability to that of the control group at 48 and 72 h of culture (p < 0.05). The same was observed for 1:4 dilutions of the tested materials at 24, 48, and 72 h of culture (p > 0.05). All the tested materials exhibited adequate cytocompatibility in the remaining biocompatibility assays. MTA exhibited a significantly higher calcium ion release compared to NeoPutty and NeoMTA Plus (p < 0.05).
CONCLUSION
The results from the present work elucidate the adequate cytocompatibility of NeoPutty, NeoMTA Plus, and MTA Angelus towards human dental pulp cells.
CLINICAL RELEVANCE
Within the limitations of the present in vitro study, our results may act as preliminary evidence for its use in vital pulp therapy as a pulp capper. However, results need to be interpreted with caution until further clinical supporting evidence is reported.
Topics: Humans; Aluminum Compounds; Calcium; Calcium Compounds; Dental Cements; Dental Pulp; Drug Combinations; Glass Ionomer Cements; Materials Testing; Oxides; Silicate Cement; Silicates
PubMed: 36053352
DOI: 10.1007/s00784-022-04682-9 -
Periodontology 2000 Oct 2019The use of dental implants is nowadays a well-accepted and highly predictable treatment modality for restoring the dentition and reestablishing the masticatory function... (Review)
Review
The use of dental implants is nowadays a well-accepted and highly predictable treatment modality for restoring the dentition and reestablishing the masticatory function of edentulous and partially edentulous patients. Despite the high predictability and excellent long-term survival rates reported for implant therapy, complications may still occur and can jeopardize both short- and long-term success. The present paper provides an overview on the most important aspects related to the etiology, prevention, and management of complications associated with implant therapy. Data from the literature indicate that a number of factors, such as surgical trauma, implant diameter, type of implant-abutment connection, abutment disconnection and reconnection, presence of microgap, and implant malpositioning, can substantially influence the biologic processes of bone remodeling and biofilm formation, thus increasing the rate of short- and long-term hard- and soft-tissue complications. Other factors, such as excess cement at cement-retained prosthetic restorations, abutment mobility, and infections (e.g. peri-implant mucositis and peri-implantitis) caused by bacterial biofilm, are further causes for complications and failures. More recent evidence also indicates that besides the need for sufficient bone volume surrounding the implant, the presence of an adequate width and thickness of attached mucosa may improve biofilm control and limit crestal bone resorption. Furthermore, emerging evidence points also to the pivotal role of human factors as one of the most important causes of complications in implant dentistry. It can be concluded that clinicians need to consider all biologic and biomechanical factors affecting implant placement and survival, as well as undergo adequate training to improve their surgical skills to control and prevent implant complications. Careful patient selection and control of environmental and systemic factors, such as smoking, diabetes etc., coupled with an accurate surgical and prosthetic planning, enable a better prevention and control of infections.
Topics: Dental Cements; Dental Implantation, Endosseous; Dental Implants; Humans; Peri-Implantitis; Stomatitis
PubMed: 31407435
DOI: 10.1111/prd.12278 -
Journal of the American Dental... Oct 2020Bonding crowns and bridges with resin cement can improve retention and reinforcement of the restoration. However, there is variation in the steps taken by different...
BACKGROUND
Bonding crowns and bridges with resin cement can improve retention and reinforcement of the restoration. However, there is variation in the steps taken by different practitioners to achieve this goal.
METHODS
The authors developed a survey on bonding dental crowns and bridges with resin cement and distributed it electronically to the American Dental Association Clinical Evaluators (ACE) Panel on May 22, 2020. The survey remained open for 2 weeks. Descriptive data analysis was conducted using SAS Version 9.4.
RESULTS
A total of 326 panelists responded to the survey, and 86% of respondents who place crowns or bridges use resin cements for bonding. When placing a lithium disilicate restoration, an almost equal proportion of respondents etch it with hydrofluoric acid in their office or asked the laboratory to do it for them, and more than two-thirds use a silane primer before bonding. For zirconia restorations, 70% reported their restorations are sandblasted in the laboratory, and 39% use a primer containing 10-methacryloyloxydecyl dihydrogen phosphate. One-half of respondents clean their lithium disilicate or zirconia restorations with a cleaning solution. Resin cements used with a primer in the etch-and-rinse mode are the most widely used. The technique used to cure and clean excess resin cement varies among respondents.
CONCLUSIONS
The types of resin cements used, tooth preparation, crown or bridge preparation, and bonding technique vary among this sample.
PRACTICAL IMPLICATIONS
Although many dentists bond crowns and bridges on the basis of best practices, improvement in the process may be achieved by dentists communicating with their laboratory to confirm the steps performed there, ensuring an effective cleaning technique is used after try-in and verifying that the correct primer is used with their chosen restorative material.
Topics: American Dental Association; Crowns; Dental Bonding; Dental Cements; Dental Materials; Dental Porcelain; Dental Stress Analysis; Humans; Materials Testing; Resin Cements; Surface Properties; Surveys and Questionnaires; United States
PubMed: 32979959
DOI: 10.1016/j.adaj.2020.07.023 -
BMC Oral Health Aug 2021White spot lesions (WSLs) often occur in orthodontic treatments. The objectives of this study were to develop a novel orthodontic cement using particles of nano silver...
BACKGROUND
White spot lesions (WSLs) often occur in orthodontic treatments. The objectives of this study were to develop a novel orthodontic cement using particles of nano silver (NAg), N-acetylcysteine (NAC) and 2-methacryloyloxyethyl phosphorylcholine (MPC), and to investigate the effects on bonding strength, biofilms and biocompatibility.
METHODS
A commercial resin-modified glass ionomer cement (RMGIC) was modified by adding NAg, NAC and MPC. The unmodified RMGIC served as the control. Enamel bond strength and cytotoxicity of the cements were investigated. The protein repellent behavior of cements was also evaluated. The metabolic assay, lactic acid production assay and colony-forming unit assay of biofilms were used to determine the antibacterial capability of cements.
RESULTS
The new bioactive cement with NAg, NAC and MPC had clinically acceptable bond strength and biocompatibility. Compared to commercial control, the new cement suppressed metabolic activity and lactic acid production of biofilms by 59.03% and 70.02% respectively (p < 0.05), reduced biofilm CFU by 2 logs (p < 0.05) and reduced protein adsorption by 76.87% (p < 0.05).
CONCLUSIONS
The new cement with NAg, NAC and MPC had strong antibacterial capability, protein-repellent ability and acceptable biocompatibility. The new cement is promising to protect enamel from demineralization during orthodontic treatments.
Topics: Anti-Bacterial Agents; Biofilms; Dental Bonding; Dental Cements; Dental Enamel; Glass Ionomer Cements; Humans; Materials Testing; Orthodontic Brackets; Resin Cements
PubMed: 34416896
DOI: 10.1186/s12903-021-01779-7 -
BMC Oral Health May 2023Enhancement of students' knowledge is essential in improving their clinical skills and performance. Thus, the curriculum should be prepared to achieve a better outcome....
BACKGROUND
Enhancement of students' knowledge is essential in improving their clinical skills and performance. Thus, the curriculum should be prepared to achieve a better outcome. The current study aimed to determine the dental students' and interns' basic knowledge towards dental luting cements and their application in dental practice to improve the theoretical and clinical training sections.
MATERIALS AND METHODS
A cross-sectional study was conducted among dental students and interns at three Colleges of Dentistry in the Kingdom of Saudi Arabia between September 2019-June 2020. An online questionnaire was used which included demographic data, questions about luting cement usage, cementation techniques, and commonly used cements in dental clinics. Descriptive analysis and chi-square test were used to show the association between level of dental education and the use of dental cements using SPSS software. The significance level was set at 5%.
RESULTS
The total respondents were 626 dental students/interns of whom 78.8% were undergraduate dental students. Participants who reported undergraduate studies as the source of information were 79.7%. The type of restoration was the main factor in luting cement selection (62.6%). Concerning the isolation technique in cementing laminate veneers, 49.7% used dri-angles, cotton rolls and saliva ejectors. Dual-cure resin cement was the most common cement used in all the mentioned restorations except in pressed porcelain laminate veneers and cement-retained implant-supported restorations.
CONCLUSIONS
Students' knowledge and practice in managing dental implants and porcelain laminate veneers need to be improved. The selection of a luting agent for a given restoration by students and interns was based on the basic knowledge, available cement, and the type of restoration. Awareness towards the management of short prepared teeth and custom-made cast posts and cores is also limited.
Topics: Humans; Dental Cements; Dental Porcelain; Prosthodontics; Cross-Sectional Studies; Saudi Arabia; Students, Dental; Resin Cements; Glass Ionomer Cements; Materials Testing
PubMed: 37254115
DOI: 10.1186/s12903-023-03054-3 -
BioMed Research International 2021This study was aimed at fabricating and evaluating the physical and bioproperties of nanofast cement (NFC) as a replacement of the MTA. The cement particles were...
This study was aimed at fabricating and evaluating the physical and bioproperties of nanofast cement (NFC) as a replacement of the MTA. The cement particles were decreased in nanoscale, and zirconium oxide was used as a radiopacifier. The setting time and radiopacity were investigated according to ISO recommendations. Analysis of color, bioactivity, and cytotoxicity was performed using spectroscopy, simulated body fluid (SBF), and MTT assay. The setting time of cement pastes significantly dropped from 65 to 15 min when the particle sizes decreased from 2723 nm to 322 nm. Nanoparticles provide large surface areas and nucleation sites and thereby a higher hydration rate, so they reduced the setting time. Based on the resulting spectroscopy, the specimens did not exhibit clinically noticeable discoloration. Resistance to discoloration may be due to the resistance of zirconium oxide to decomposition. Scanning electron microscopy (SEM), X-ray diffraction (XRD), and infrared spectroscopy (FTIR) examinations of the immersed SBF samples showed apatite formation that was a reason for its suitable bioactivity. The results of cell culture revealed that NFC is nontoxic. This study showed that NFC was more beneficial than MTA in dental restorations.
Topics: Bismuth; Bone Cements; Calcium Compounds; Calcium Hydroxide; Dental Cements; Dental Restoration, Permanent; Glass Ionomer Cements; Materials Testing; Microscopy, Electron, Scanning; Nanostructures; Oxides; Root Canal Filling Materials; Silicates; Surface Properties; Water; X-Ray Diffraction; Zirconium
PubMed: 34540997
DOI: 10.1155/2021/7343147 -
Dental Materials : Official Publication... Dec 2023The aims of this study were to systematically review the literature and compare the relative effects of various luting agents on bonding between glass-fiber posts and... (Meta-Analysis)
Meta-Analysis Review
OBJECTIVES
The aims of this study were to systematically review the literature and compare the relative effects of various luting agents on bonding between glass-fiber posts and root canal dentin in short- and long-term aging conditions.
DATA/SOURCES
The literature was electronically searched in PubMed, Embase, and Scopus. A manual search was performed by scanning the reference lists of the included studies.
STUDY SELECTION
Two reviewers independently conducted the selection of studies, data extraction, and risk of bias assessment. Pairwise meta-analyses were based on random effect models. Network meta-analyses were conducted within a frequentist framework with a multivariable random effects approach. The standardized mean difference and 95% confidence interval was calculated.
RESULTS
One hundred and eighteen studies were included and assessed the effects of five luting agents. For pairwise meta-analyses, in short-term aging conditions, a significantly higher bond strength of self-adhesive resin cement (SARC) compared to etch-and-rinse adhesive composite resin core material (ERCM) in the total, coronal, and middle regions. In long-term aging conditions, a significantly higher bond strength of ERCM compared to etch-and-rinse adhesive resin cement (ERRC) in all regions. Furthermore, SARC showed a significantly higher bond strength compared to self-etch adhesive composite resin core material (SECM) in the total, middle, and apical regions. For network meta-analyses, in the apical region, a significantly higher bond strength of SARC compared to ERRC in both aging conditions.
CONCLUSIONS
The SARC tended to be the most effective luting agent in bonding between glass-fiber posts and root canal dentin in short- and long-term aging conditions.
Topics: Dental Cements; Resin Cements; Dental Bonding; Network Meta-Analysis; Dental Pulp Cavity; Composite Resins; Post and Core Technique; Dentin; Materials Testing; Dentin-Bonding Agents; Glass
PubMed: 37845166
DOI: 10.1016/j.dental.2023.10.015 -
Dental Materials : Official Publication... Jan 2022The aim of this study was to evaluate the mechanical properties, bonding performance and anti-microbial activity of a novel composite cement containing cetylpyridinium...
OBJECTIVES
The aim of this study was to evaluate the mechanical properties, bonding performance and anti-microbial activity of a novel composite cement containing cetylpyridinium chloride (CPC) modified montmorillonite ('CPC-Mont'), and using these parameters to determine the optimal particle size and concentration of CPC-Mont the composite cement can be loaded with.
METHODS
CPC-Mont particles with a median diameter of 30 and 7 µm were prepared and added to a composite cement at a concentration of 2, 3, 4, 5 and 7.5 wt%. Mechanical properties and bonding performance of the experimental composite cements were evaluated by 3-point bending and micro-tensile bond-strength testing. The amount of CPC released from the cement disks was quantified using a UV-vis recording spectrophotometer. The anti-biofilm activity was studied using scanning electron microscopy (SEM).
RESULTS
Adding 30-μm CPC-Mont decreased the mechanical properties and bonding performance of the composite cement, while no reduction was observed for the 7-μm CPC-Mont loaded cement formulation. Although CPC release substantially decreased during the 7-day period assessed, 5- and 7.5-wt% CPC-Mont loaded composite cement inhibited biofilm formation for 30 days.
SIGNIFICANCE
Loading composite cement with CPC-Mont with a median diameter of 7 µm at concentrations of 5-7.5 wt% was effective in achieving continuous anti-biofilm activity, while maintaining mechanical strength and bonding performance.
Topics: Bentonite; Bone Cements; Cetylpyridinium; Dental Bonding; Dental Cements; Materials Testing; Resin Cements; Surface Properties
PubMed: 34930623
DOI: 10.1016/j.dental.2021.10.009 -
The Journal of Prosthetic Dentistry Mar 2023Cement at the restorative margin after implementation of the manufacturer's recommended procedure for cement cleanup has not been extensively evaluated.
STATEMENT OF PROBLEM
Cement at the restorative margin after implementation of the manufacturer's recommended procedure for cement cleanup has not been extensively evaluated.
PURPOSE
The purpose of this in vitro study was to use microcomputed tomography (μCT) to evaluate the number, volume, and width of voids left at the margin when dental cement is cleaned during the cementation process as per 2 manufacturer-prescribed methods for cement cleanup by evaluating a self-adhesive resin cement and a resin-modified glass ionomer cement.
MATERIAL AND METHODS
Twenty molar Ivorine Typodont prepared teeth were scanned, and lithium disilicate crowns were milled and cemented to the prepared teeth as per the manufacturer-recommended cementation process. Two methods of cement cleanup were performed: the excess cement was tack-polymerized with a polymerization light, or a delay of 3 minutes was used for the excess cement to reach partial polymerization, and the excess cement was removed with a sharp sickle scaler. These 2 methods of cement cleanup were performed with 2 cements: a resin-modified glass ionomer cement and a self-adhesive resin. Each specimen was then scanned with a μCT machine. The buccal margin of each specimen, from mesiobuccal line angle to distobuccal line angle, was examined, and the number, volume, and width of any voids remaining at the margin open to the environment were measured. For statistical analysis, the specimens were first grouped by method of cement cleanup and then grouped by cement type. The Wilcoxon ranked sum test was implemented because of the lack of a normal distribution and the heterogeneity of the data (α=.05).
RESULTS
No statistically significant difference was found in the median number of voids, median volume of voids, or median width per void between the 2 cleanup methods, irrespective of cement type (P>.05). Significant differences were found in the median number of voids, median volume of voids, and median width per void when comparing cement types, irrespective of cement cleanup methods (P<.05).
CONCLUSIONS
The choice of cement may be more important than the method of cement cleanup when considering voids left at the margin. Microcomputed tomography is an excellent nondestructive tool for volumetric measurements of voids at the margin.
Topics: Resin Cements; X-Ray Microtomography; Glass Ionomer Cements; Cementation; Crowns; Materials Testing; Dental Cements
PubMed: 34229897
DOI: 10.1016/j.prosdent.2021.06.010 -
Current Pharmaceutical Biotechnology 2022Nanotechnology is considered one of the emerging fields of science that has influenced diverse applications, including food, biomedicine, and cosmetics. The production... (Review)
Review
Nanotechnology is considered one of the emerging fields of science that has influenced diverse applications, including food, biomedicine, and cosmetics. The production and usage of materials with nanoscale dimensions like nanoparticles are attractive parts of nanotechnology. Among different nanoparticles, zinc phosphate nanoparticles have attracted attention due to their biocompatibility, biosafety, non-toxicity, and environmental compatibility. These nanoparticles could be employed in various applications like anticorrosion, antibacterial, dental cement, glass ceramics, tissue engineering, and drug delivery. A variety of physical, chemical, and green synthesis methods have been used to synthesize zinc phosphate nanoparticles. All these methods have some limitations along with certain advantages. Chemical approaches may cause health risks and environmental problems due to the toxicity of hazardous chemicals used in these techniques. Moreover, physical methods require high amounts of energy as well as expensive instruments. However, biological methods are free of chemical contaminants and eco-friendly. This review is aimed to explore different methods for the synthesis of zinc phosphate nanoparticles, including physical, chemical, and more recently, biological approaches (using various sources such as plants, algae, and microorganisms). Also, it summarizes the practicable applications of zinc phosphate nanoparticles as anticorrosion pigment, dental cement, and drug delivery agents.
Topics: Dental Cements; Green Chemistry Technology; Metal Nanoparticles; Phosphates; Plants; Zinc Compounds
PubMed: 34779369
DOI: 10.2174/1389201022666211015115753