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Environmental Research Oct 2019Per- and polyfluoroalkyl substances (PFAS) are a group of water-soluble chemical compounds with an important number of applications, which have been widely used during... (Review)
Review
Per- and polyfluoroalkyl substances (PFAS) are a group of water-soluble chemical compounds with an important number of applications, which have been widely used during the last 60 years. Two of them, perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA), are the most known and well investigated. As for many other organic substances that are of environmental concern, the diet is the main route of human exposure to PFAS. However, in certain cases drinking water may also mean a significant contribution to human exposure, and to a lesser extent, dust and air (indoor exposure). In recent years, the environmental persistence of PFAS, their biomagnification in food webs, as well as their potential accumulation and toxicity, have generated a notable interest, which has been evidenced by the considerable number of publications in this regard. Recently, we carried out a wide revision on the levels of PFAS in food and human dietary intake. In the current review, we have summarized the recent information (last 10 years) published in the scientific literature (Scopus and PubMed) on the concentrations of PFAS in drinking water and the human health risks derived from the regular water consumption, when available. A large amount of data belongs to PFOS and PFOA and corresponds to studies mainly conducted in countries of the European Union, USA and China, although no information is available for most countries over the world. According to the toxicological information about PFAS that is so far available, the current health risks for the regular consumers of municipal/tap water do not seem to be of concern according to the levels considered as acceptable for various regulatory institutions.
Topics: Dietary Exposure; Drinking Water; Fluorocarbons; Humans; Water Pollutants, Chemical
PubMed: 31421451
DOI: 10.1016/j.envres.2019.108648 -
International Journal of Environmental... Jan 2021The ubiquitous problem of pesticide in aquatic environment are receiving worldwide concern as pesticide tends to accumulate in the body of the aquatic organism and... (Review)
Review
The ubiquitous problem of pesticide in aquatic environment are receiving worldwide concern as pesticide tends to accumulate in the body of the aquatic organism and sediment soil, posing health risks to the human. Many pesticide formulations had introduced due to the rapid growth in the global pesticide market result from the wide use of pesticides in agricultural and non-agricultural sectors. The occurrence of pesticides in the water body is derived by the runoff from the agricultural field and industrial wastewater. Soluble pesticides were carried away by water molecules especially during the precipitation event by percolating downward into the soil layers and eventually reach surface waters and groundwater. Consequently, it degrades water quality and reduces the supply of clean water for potable water. Long-time exposure to the low concentration of pesticides had resulted in non-carcinogenic health risks. The conventional method of pesticide treatment processes encompasses coagulation-flocculation, adsorption, filtration and sedimentation, which rely on the phase transfer of pollutants. Those methods are often incurred with a relatively high operational cost and may cause secondary pollution such as sludge formation. Advanced oxidation processes (AOPs) are recognized as clean technologies for the treatment of water containing recalcitrant and bio-refractory pollutants such as pesticides. It has been adopted as recent water purification technology because of the thermodynamic viability and broad spectrum of applicability. This work provides a comprehensive review for occurrence of pesticide in the drinking water and its possible treatment.
Topics: Agriculture; Drinking Water; Environmental Monitoring; Groundwater; Humans; Pesticides; Water Pollutants, Chemical
PubMed: 33430077
DOI: 10.3390/ijerph18020468 -
Biological Trace Element Research Jan 2023Iodine is a micronutrient essential for maintaining normal body functioning, and the consumption depends on the distribution in the environment, and insufficient or... (Meta-Analysis)
Meta-Analysis Review
Iodine is a micronutrient essential for maintaining normal body functioning, and the consumption depends on the distribution in the environment, and insufficient or excessive intake results in thyroid dysfunction. The purpose of this review was to evaluate the correlation between iodine concentration in drinking water and the iodine status of the population. The systematic review was conducted following the PRISMA guidelines and was registered at the International Prospective Register of Ongoing Systematic Reviews (CRD42019128308). A literature search was conducted using MEDLINE/PUBMED (National Library of Medicine), LILACS (Latin-American and Caribbean Literature on Health Sciences), and Cochrane Library, June 2021. The quality of the studies was assessed by a checklist for cross-sectional studies developed by Joanna Briggs Institute. The initial search identified 121 articles, out of which ten were included in this systematic review, and five were included in the meta-analysis. Among the articles listed, six adopted cutoff points to classify the iodine content in the drinking water. The study identified median iodine concentration in drinking water from 2.2 to 617.8 μg/L and the correlation between iodine concentration in drinking water and urinary iodine concentration was 0.92, according to meta-analysis. Furthermore, the iodine status was correlated to the iodine content in water. The determination of a cutoff point can contribute to the implementation of iodine consumption control measures.
Topics: Humans; Iodine; Drinking Water; Goiter; Cross-Sectional Studies; Nutritional Status
PubMed: 35075595
DOI: 10.1007/s12011-022-03127-4 -
Environmental Toxicology and Chemistry Mar 2021Per- and polyfluoroalkyl substances (PFAS), a class of synthetic chemicals produced for over 70 years, are of increasing concern because of their widespread... (Review)
Review
Per- and polyfluoroalkyl substances (PFAS), a class of synthetic chemicals produced for over 70 years, are of increasing concern because of their widespread environmental presence, extreme persistence, bioaccumulative nature, and evidence for health effects from environmentally relevant exposures. In 2016, the United States Environmental Protection Agency (USEPA) established nonregulatory drinking water Health Advisories of 70 ng/L for individual and total concentrations of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS), the 8-carbon perfluoroalkyl acids (PFAAs) that are the most thoroughly studied PFAS. As of May 2020, 9 US states had concluded that the USEPA Health Advisories are insufficiently protective and developed more stringent PFOA and PFOS guidelines. In addition, 10 states had developed guidelines for other PFAS, primarily PFAAs. This Critical Review discusses the scientific basis for state and USEPA drinking water guidelines for PFOA and PFOS; the same principles apply to guidelines for other PFAS. Similarities and differences among guidelines arise from both toxicity and exposure considerations. The approximately 4-fold range among state guidelines (8-35 ng/L for PFOA, 10-40 ng/L for PFOS) is not large or unexpected for guidelines developed by different scientists at different time points, especially when compared with older USEPA and state guidelines that were generally several orders of magnitude higher. Additional state guidelines for PFOA, PFOS, and other PFAS are expected to become available. Environ Toxicol Chem 2021;40:560-563. © 2020 SETAC.
Topics: Alkanesulfonic Acids; Bioaccumulation; Drinking Water; Fluorocarbons; United States; United States Environmental Protection Agency; Water Pollutants, Chemical
PubMed: 32845526
DOI: 10.1002/etc.4863 -
MMW Fortschritte Der Medizin May 2021
Review
Topics: Drinking Water; Humans; Lithium; Research; Suicide
PubMed: 33961249
DOI: 10.1007/s15006-021-9941-4 -
The Science of the Total Environment Feb 2024Microplastics (MPs) have entered drinking water (DW) via various pathways, raising concerns about their potential health impacts. This study provides a comprehensive... (Review)
Review
Microplastics (MPs) have entered drinking water (DW) via various pathways, raising concerns about their potential health impacts. This study provides a comprehensive review of MP-associated chemicals, such as oligomers, plasticizers, stabilizers, and ultraviolet (UV) filters that can be leached out during DW treatment and distribution. The leaching of these chemicals is influenced by various environmental and operating factors, with three major ones identified: MP concentration and polymer type, pH, and contact time. The leaching process is substantially enhanced during the disinfection step of DW treatment, due to ultraviolet light and/or disinfectant-triggered reactions. The study also reviewed human exposure to MPs and associated chemicals in DW, as well as their health impacts on the human nervous, digestive, reproductive, and hepatic systems, especially the neuroendocrine toxicity of endocrine-disrupting chemicals. An overview of MPs in DW, including tap water and bottled water, was also presented to enable a background understanding of MPs-associated chemicals. In short, certain chemicals leached from MPs in DW can have significant implications for human health and demand further research on their long-term health impacts, mitigation strategies, and interactions with other pollutants such as disinfection byproducts (DBPs) and per- and polyfluoroalkyl substances (PFASs). This study is anticipated to facilitate the research and management of MPs in DW and beverages.
Topics: Humans; Microplastics; Plastics; Drinking Water; Polymers; Water Purification; Water Pollutants, Chemical
PubMed: 38154642
DOI: 10.1016/j.scitotenv.2023.169594 -
Trends in Microbiology Aug 2019Now is an opportune time to foster collaborations across sectors and geographical boundaries to enable development of best practices for drinking water (DW) microbiome... (Review)
Review
Now is an opportune time to foster collaborations across sectors and geographical boundaries to enable development of best practices for drinking water (DW) microbiome research, focusing on accuracy and reproducibility of meta-omic techniques (while learning from past microbiome projects). A large-scale coordinated effort that builds on this foundation will enable the urgently needed comprehensive spatiotemporal understanding and control of DW microbiomes by engineering interventions to protect public health. This opinion paper highlights the need to initiate and conduct a large-scale coordinated DW microbiome project by addressing key knowledge gaps and recommends a roadmap for this effort.
Topics: Drinking Water; Humans; Microbiota; Water Microbiology
PubMed: 31031092
DOI: 10.1016/j.tim.2019.03.011 -
International Journal of Geriatric... Mar 2023Lithium, a mood stabilizer, is known to exhibit neuroprotective effects in animal models and may have anti-dementia effects.
BACKGROUND
Lithium, a mood stabilizer, is known to exhibit neuroprotective effects in animal models and may have anti-dementia effects.
AIMS
We used data from Scottish Mental Survey 1932, a population-based cohort study, to investigate the association between lithium in drinking water and dementia rate in humans.
METHOD
Lithium levels in drinking water from 285 sampling sites across Scotland dating from 2014 were obtained from the sole public water provider (Scottish Water). Dementia and non dementia cases were identified from cohort data by electronic health records until 2012, and linked to postcode.
RESULTS
The mean lithium level at all sampling sites was 1.45 μg/L (SD 1.83, range 0.5-18.2) and was 1.26 (SD 0.63, range 0.55-9.19) for sites matched to participant data. Of 37,597 study members, 3605 developed dementia until June 2012. Lithium levels were positively associated with the risk of dementia in women (highest in second quartile, HR 1.17, 95%CI 1.04-1.32), but there was no relationship in men (highest in second quartile, HR 0.95, 95% CI 0.81-1.12). The pattern of association was explored further by decile, and in females there was an association between lithium level and increased dementia risk compared to the lowest decile (0.55-0.68 μg/L) in all deciles except the highest, corresponding with lithium levels 0.68-2.1 μg/L.
CONCLUSIONS
Lithium levels in drinking water are very low across Scotland which limited detection of potential effect. Our results do not support an association between extremely low levels of lithium and later dementia risk. We found a trend to increased risk in females at lithium levels below but not above 2.1 μg/L.
Topics: Male; Humans; Female; Lithium; Cohort Studies; Drinking Water; Surveys and Questionnaires
PubMed: 36747488
DOI: 10.1002/gps.5890 -
Journal of Water and Health Jul 2022Phosphate-based drinking water softeners are commonly used to prevent scale formation in drinking water distribution infrastructure. The main reason for drinking water...
Phosphate-based drinking water softeners are commonly used to prevent scale formation in drinking water distribution infrastructure. The main reason for drinking water softening is primarily economic (protection of pipes and extension of equipment life), while the health aspect of such treatment is usually neglected. The aim of this work is to investigate the effects of phosphate-based drinking water softeners on growth stimulation of Legionella pneumophila. Bacterial growth was observed at two different phosphate concentrations. On average, an increase in growth of 1.19-1.28 log CFU/mL was observed in selected samples with added phosphates compared with the control. The results of the in vitro experiment confirmed that the added phosphates stimulate the growth of L. pneumophila; growth stimulation could therefore be expected in drinking water distribution systems (DWDS) when phosphates are used as well. The availability of phosphorus in DWDS may be a crucial limiting factor for biofouling control. Consequently, phosphate-based chemicals for drinking water should be avoided or used with prudence, especially in drinking water with high concentrations of other nutrients.
Topics: Drinking Water; Legionella; Legionella pneumophila; Phosphates; Water Microbiology; Water Supply
PubMed: 35902990
DOI: 10.2166/wh.2022.055 -
Environmental Geochemistry and Health Jun 2023Calcium (Ca) and magnesium (Mg) in drinking water and the relevant health effects have been ignored for too long. This study aims to reveal the concentrations, spatial...
Calcium (Ca) and magnesium (Mg) in drinking water and the relevant health effects have been ignored for too long. This study aims to reveal the concentrations, spatial distributions, origins and contributions to the daily estimated average requirements of Ca and Mg in public drinking water. Using hydrochemical data of collected samples of public drinking water in 314 cities across China, the contributions of Ca and Mg intakes from public drinking water to their daily estimated average requirements (EARs) were assessed. And the significance of Ca/Mg ratio and total hardness (TH) was evaluated as well. The Ca and Mg concentrations of the samples were in the range of 2.5-155.1 mg/L and 0.2-81.9 mg/L, with an average of 40.4 mg/L and 12.4 mg/L, respectively. There exist obvious differences in Ca and Mg concentrations in different regions, under the impact of climate conditions and water-rock interactions. The intake of Ca via the consumption of public drinking water for adults may be twice as much as that for other age groups. In cities with high Ca levels in public drinking water, the Ca contributions to EAR could reach up to 51.59% for adults. By contrast, Mg in drinking water is an important and even the main pathway to ingest Mg for infants and children. Therefore, public drinking water is critical for Ca and Mg intake among urban residents of China. Besides, attention should be paid to the health effects of high Ca/Mg ratio and low TH in public drinking water, especially in southern China. This research is the first systematic and comprehensive national scale study of Ca and Mg in public drinking water and can provide an important reference to improve healthy public drinking water standards around the world.
Topics: Adult; Child; Humans; Drinking Water; Calcium; Magnesium; Water Supply; China
PubMed: 36342636
DOI: 10.1007/s10653-022-01416-4