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Medical Mycology Case Reports Dec 2019Mycetoma is a chronic-granulomatous disease characterized by the inflammation, swollen organ, draining sinuses containing blood, pus, and grains. We present a case of...
Mycetoma is a chronic-granulomatous disease characterized by the inflammation, swollen organ, draining sinuses containing blood, pus, and grains. We present a case of madura foot with novel etiologic agent Diagnosis was based on morphologic, physiologic, histipathologic and molecular methods. antifungal susceptibility tests revealed that MIC values for itraconazole, amphotericin B, and posaconazole were 0.0313 μg/ml, 0.0313 μg/ml, and 0.004 μg/ml, respectively. The patient was treated and recovered by itraconazole(400 mg/day) after prolonged course.
PubMed: 31667052
DOI: 10.1016/j.mmcr.2019.09.005 -
Journal de Mycologie Medicale Apr 2020Mycetoma remains endemic in the tropical and subtropical regions of the "mycetoma belt" including Senegal. It affects more commonly young men in the age group of 20 to...
Mycetoma remains endemic in the tropical and subtropical regions of the "mycetoma belt" including Senegal. It affects more commonly young men in the age group of 20 to 40 years. The foot represents the most commonly affected site. The most common extra-podal localizations are leg, knee, buttocks, hand and arm. We report an exceptional case of cervical fungal mycetoma that occurred in a 13-year-old Senegalese child. He consulted for a cervico-submandibular tumefaction with multiple sinuses and black grains discharge evolving since 6 years, associated to laryngeal dyspnoea. Mycological examination with culture isolated Madurella mycetomatis. Cervical CT Scan showed bone and soft tissue invasion. Terbinafine alone was administered. During the evolution, tracheotomy was performed following the aggravation of the laryngeal disorders. Death from severe sepsis occurred after 8 months of evolution. The particularities of our case are the occurrence of fungal mycetoma in a child, the cervical localization and the difficulties of therapeutic management largely due to the diagnostic delay.
Topics: Adolescent; Child; Delayed Diagnosis; Dyspnea; Fatal Outcome; Granuloma, Laryngeal; Humans; Madurella; Mycetoma; Senegal; Sepsis; Terbinafine; Thyroid Cartilage; Tracheotomy
PubMed: 31864802
DOI: 10.1016/j.mycmed.2019.100914 -
Plants (Basel, Switzerland) May 2024The synthesis of betalain using microorganisms is an innovative developmental technology, and the excavation of microorganisms closely related to betalain can provide...
The synthesis of betalain using microorganisms is an innovative developmental technology, and the excavation of microorganisms closely related to betalain can provide certain theoretical and technical support to this technology. In this study, the characteristics of soil microbial community structures and their functions in the rhizospheres of white-fleshed dragon fruit () and red-fleshed dragon fruit () were analyzed. The results show that the soil bacterial and fungal compositions in the rhizospheres were shaped differently between and . Bacterial genera such as and were the unique dominant soil bacterial genera in the rhizospheres of , whereas was the unique dominant soil bacterial genus in the rhizospheres of . Additionally, was the unique dominant soil fungal genus in the rhizospheres of , whereas and were the unique dominant soil fungal genera in the rhizospheres of . Moreover, , , , , , , , and were significantly enriched in the rhizospheres of , whereas , , , , and were significantly enriched in the rhizospheres of . Furthermore, the relative abundances of Ascomycota and were significantly higher in the rhizospheres of than in those of .
PubMed: 38794417
DOI: 10.3390/plants13101346 -
Mycopathologia Jun 2021This report describes the phenotypic characteristics of a novel fungal species, isolated from a prosthetic hip infection. The patient, who had undergone multiple total...
This report describes the phenotypic characteristics of a novel fungal species, isolated from a prosthetic hip infection. The patient, who had undergone multiple total hip arthroplasties due to Legg-Calvé-Perthes disease, presented with continued fever and wound dehiscence. Findings upon incision and draining were notable for necrotic tissue and a sinus tract from the fluid collection. Intraoperative cultures were positive for a sterile filamentous fungus. BLASTn results following DNA sequencing placed the isolate within the family Chaetomiaceae close to the genera Madurella, Canariomyces, Stolonocarpus, Stellatospora, Ovatospora, Carteria and Melanocarpus. Phylogenetic analysis demonstrated that the isolate was a new thielavia-like species, Pseudocanariomyces americanus. Antifungal susceptibility was performed, and low minimum inhibitory concentrations were observed with amphotericin B, itraconazole, posaconazole, and voriconazole. The patient was initially treated with voriconazole but was switched to posaconazole secondary to a photosensitivity reaction. Acceptable posaconazole trough concentrations were achieved, and the patient remained stable without pain or drainage from her surgical incision.
Topics: Amphotericin B; Antifungal Agents; Ascomycota; Female; Humans; Microbial Sensitivity Tests; Phylogeny; Voriconazole
PubMed: 34013385
DOI: 10.1007/s11046-021-00555-z -
Indian Journal of Medical Microbiology Apr 2021Simultaneous double mycetoma is a rare presentation. Worldwide only three to four cases are found in literature. Here we report such an unusual case, to the best of our...
Simultaneous double mycetoma is a rare presentation. Worldwide only three to four cases are found in literature. Here we report such an unusual case, to the best of our knowledge first documented case from India, where a 60 years old male farmer presented with double eumycetoma in different sites of same limb with discharge of black and white grains, which conventionally diagnosed as Madurella grisea from foot and Acremonium falciformi from buttock respectively.
Topics: Buttocks; Foot; Fusarium; Humans; India; Madurella; Male; Middle Aged; Mycetoma
PubMed: 33966864
DOI: 10.1016/j.ijmmb.2020.09.002 -
Indian Journal of Medical Microbiology 2024Eumycetoma caused by Madurella fahalii, a drug-resistant fungus, has never been reported in India. Here, we describe a fatal case of eumycetoma with spinal involvement...
Eumycetoma caused by Madurella fahalii, a drug-resistant fungus, has never been reported in India. Here, we describe a fatal case of eumycetoma with spinal involvement due to M. fahalii for the first time in India.
Topics: Humans; India; Mycetoma; Madurella; Male; Fatal Outcome; Spine; Antifungal Agents
PubMed: 38158183
DOI: 10.1016/j.ijmmb.2023.100523