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World Journal of Clinical Cases Aug 2022Rectal mature teratoma is rare and has been reported as a case report in this study. Herein, clinical presentation, magnetic resonance imaging findings, and...
BACKGROUND
Rectal mature teratoma is rare and has been reported as a case report in this study. Herein, clinical presentation, magnetic resonance imaging findings, and immunohistochemistry showed a pelvic rectal mature teratoma. The case report and the surgical treatment procedure have been discussed below.
CASE SUMMARY
A 29-year-old Chinese female showed up with over a 1-mo history of perianal mass that emerged after defecation. Physical examination indicated that the mass was 4 cm × 3 cm × 3 cm. The intraoperative procedure involved ligation of the sigmoid colon 10 cm above the upper edge of the tumor, followed by ligation of the rectum 3.5 cm above the upper edge of the tumor, and subsequent complete removal of the mass. The histopathology confirmed the mature teratoma.
CONCLUSION
The tumor can be completely removed using surgery to prevent its recurrence.
PubMed: 36158485
DOI: 10.12998/wjcc.v10.i22.7883 -
CMAJ : Canadian Medical Association... Mar 2021
Topics: Abdominal Pain; Dermoid Cyst; Female; Humans; Narration; Ontario; Physician-Patient Relations; Quarantine; Young Adult
PubMed: 33722834
DOI: 10.1503/cmaj.210381 -
The Pan African Medical Journal 2021
Topics: Dermoid Cyst; Humans
PubMed: 34909087
DOI: 10.11604/pamj.2021.40.99.31816 -
ANZ Journal of Surgery Mar 2023
Topics: Humans; Pericardium; Teratoma; Dermoid Cyst
PubMed: 35775405
DOI: 10.1111/ans.17891 -
American Journal of Obstetrics and... Sep 2021
Topics: Adult; Dermoid Cyst; Female; Humans; Magnetic Resonance Imaging; Vaginal Neoplasms
PubMed: 33713684
DOI: 10.1016/j.ajog.2021.03.010 -
Japanese Journal of Radiology Feb 2021Teratoma is a germ cell tumor (GCT) derived from stem cells of the early embryo and the germ line. Teratoma is the most common neoplasm of the ovaries and is usually... (Review)
Review
Teratoma is a germ cell tumor (GCT) derived from stem cells of the early embryo and the germ line. Teratoma is the most common neoplasm of the ovaries and is usually diagnosed easily using imagings by detecting fat components. However, there are various histopathological types and the imaging findings differ according to the type. Teratoma usually occurs in the gonads or in the midline due to migration of primordial germ cells during development. The clinical course of teratomas depends on the age of the patient, histological type, and anatomical site. Sometimes teratomas show unusual manifestations, such as mature teratoma without demonstrable fat components, torsion, rupture, growing teratoma syndrome, anti-N-methyl-D-aspartate receptor encephalitis, and autoimmune hemolytic anemia. For all of these reasons, teratomas demonstrate a wide spectrum of imaging features and radiologists should be familiar with these variabilities. The present article aims to introduce a model encompassing types of GCTs based on their developmental potential, and to review several histopathological types in various anatomical sites and unusual manifestations of teratomas, with representative imaging findings.
Topics: Diagnostic Imaging; Female; Humans; Magnetic Resonance Imaging; Male; Neoplasms, Germ Cell and Embryonal; Ovarian Neoplasms; Teratoma; Tomography, X-Ray Computed
PubMed: 32875471
DOI: 10.1007/s11604-020-01035-y -
Journal of Neurosurgery. Case Lessons Aug 2022Central nervous system (CNS) mature teratoma is a rare disease with symptoms that can vary according to tumor location. Most lesions are benign; rarely, malignancy can...
BACKGROUND
Central nervous system (CNS) mature teratoma is a rare disease with symptoms that can vary according to tumor location. Most lesions are benign; rarely, malignancy can develop in any of the somatic components. Elevated levels of tumor markers such as α-fetoprotein and β-human chorionic gonadotropin are not usually found in patients with CNS mature teratoma, and no reports have described an association with carbohydrate antigen 19-9 (CA19-9).
OBSERVATIONS
A 64-year-old woman with headache was found to have a mass lesion in the anterior cranial fossa. Magnetic resonance imaging of the brain suggested a mature teratoma. Serum and cerebrospinal fluid (CSF) tests showed significant CA19-9 elevations (2,770 U/mL and 4,387 U/mL, respectively). Other examinations, including whole-body 18F-fluorodeoxyglucose positron emission tomography, did not detect the origin of elevated CA19-9, suggesting that the high CA19-9 levels were caused by intracranial tumor. The patient underwent tumor removal. The histopathological diagnosis was mature teratoma with positive CA19-9 staining. CA19-9 levels in serum and CSF decreased significantly after tumor removal.
LESSONS
The histopathological findings and postoperative decreased CA19-9 levels established the diagnosis of CA19-9-producing CNS mature teratoma. CNS mature teratoma can cause elevations in CA19-9 in cases with absence of neoplasms in the trunk.
PubMed: 36088553
DOI: 10.3171/CASE22230 -
Child's Nervous System : ChNS :... Jan 2023Sacrococcygeal teratoma (SCT) is a rare congenital tumor originating from a variant of extragonadal germ cell neoplasm. Herein, we present three cases of neonatal SCTs... (Review)
Review
PURPOSE
Sacrococcygeal teratoma (SCT) is a rare congenital tumor originating from a variant of extragonadal germ cell neoplasm. Herein, we present three cases of neonatal SCTs undergoing surgical resection and reconstruction. We also review the literature to discuss the importance of proper perinatal management and timely surgical intervention depending on the tumor type and maturity to prevent malignant transformation and recurrence and ensure functional outcomes.
METHODS AND RESULTS
Three cases of SCT were retrospectively analyzed. All infants underwent complete surgical resection of the SCT and coccygectomy during their neonatal/infancy period, followed by pelvic floor and buttock reconstruction while minimizing buttock contour deformity and undesirable skin scar. Two of the cases were histopathologically diagnosed as predominantly cystic mature teratomas of Altman types I and IV, and the third was a mature teratoma of Altman type II. There were no complications or tumor recurrence during the average follow-up period of 5.3 years.
CONCLUSIONS
This case-based review highlights the role of multidisciplinary team approaches, including prenatal monitoring, oncologic resection, and adequate reconstruction according to the type of tumor and anomaly. Optimal perinatal evaluation allows promising oncologic and functional outcomes in terms of timely intervention to eliminate tumor recurrence and malignant transformation. Complete oncologic surgical resection of SCTs should also include proper functional preservation strategies, such as the reconstruction of the pelvic floor, cosmetic buttock contouring, and preservation of bladder and bowel sphincter function.
Topics: Infant; Infant, Newborn; Pregnancy; Female; Humans; Neoplasm Recurrence, Local; Retrospective Studies; Sacrococcygeal Region; Teratoma; Neoplasms, Germ Cell and Embryonal; Spinal Neoplasms; Dermoid Cyst
PubMed: 36422695
DOI: 10.1007/s00381-022-05768-1 -
Journal of Pediatric and Adolescent... Apr 2023To examine the recurrence rates of pediatric benign ovarian neoplasms METHODS: A retrospective review of females up to 21 years of age who underwent surgery for a benign...
STUDY OBJECTIVE
To examine the recurrence rates of pediatric benign ovarian neoplasms METHODS: A retrospective review of females up to 21 years of age who underwent surgery for a benign ovarian neoplasm at 8 pediatric hospitals from January 2010 through December 2016 was conducted. Data include primary operation details, follow-up imaging, and reoperation details.
RESULTS
Four hundred and twenty-six females were included in our cohort, with a median age of 15 years at the time of the primary operation. Of the patients, 69% had a mature teratoma, 18% had a serous cystadenoma, and 8% had a mucinous cystadenoma. Two-thirds of patients underwent ovarian-sparing surgery. There were 11 pathologically confirmed recurrences (2.6%) at a median follow-up of 12.8 months. The pathologically confirmed recurrence was 10.5 per 100 person-months at 12 months (SE = 5.7) for mucinous cystadenomas and 0.4 months (SE = 0.4) for mature teratomas (P = .001). For half of the patients, the pathologically confirmed recurrences occurred by 12.8 months, and for 75%, they occurred by 23.3 months. There were no differences in reoperation or recurrence on the basis of initial procedure (ovary-sparing surgery vs oophorectomy).
CONCLUSION
We measured the pathologically confirmed recurrence rate for pediatric benign ovarian neoplasms in a large cohort. Oophorectomy was not protective against recurrence. Mucinous cystadenomas were at a greater risk of pathologically confirmed recurrence.
Topics: Child; Humans; Female; Adolescent; Cystadenoma, Mucinous; Ovarian Neoplasms; Teratoma; Dermoid Cyst; Retrospective Studies
PubMed: 36496105
DOI: 10.1016/j.jpag.2022.11.006 -
Radiology Apr 2024
Topics: Humans; Dermoid Cyst; Magnetic Resonance Imaging; Brain Neoplasms; Tomography, X-Ray Computed; Female; Male; Diagnosis, Differential; Adult
PubMed: 38687215
DOI: 10.1148/radiol.232952