-
Indian Journal of Pathology &... 2023Teratomas are germ cell tumors occurring usually in gonadal organs. They are neoplasms composed of one or more of the three germ layers. Extragonadal teratomas are... (Review)
Review
Teratomas are germ cell tumors occurring usually in gonadal organs. They are neoplasms composed of one or more of the three germ layers. Extragonadal teratomas are uncommonly reported in the literature. The liver is an extremely rare site for teratoma, constituting < 1% of all teratomas. The majority of the liver teratomas are found in the pediatric population with only a dozen cases reported in adults to the best of our knowledge. We present a case of a 27-year-old male with a history of abdominal pain of 5 months duration. CT scan revealed liver mass suggesting teratoma. The patient underwent cholecystectomy and segmental liver resection. Histopathology revealed mature cystic teratoma. Complete resection remains the best treatment option. Teratomas of the liver are extremely rare, constituting < 1% of all teratomas. An extensive review of the literature yielded < 50 cases of primary hepatic teratomas with only a dozen cases in adults and only two cases in males.
Topics: Adult; Humans; Male; Dermoid Cyst; Hepatectomy; Liver; Neoplasms, Germ Cell and Embryonal; Teratoma
PubMed: 38084546
DOI: 10.4103/ijpm.ijpm_430_21 -
Journal of Minimally Invasive Gynecology Jul 2021
Topics: Dermoid Cyst; Fallopian Tubes; Female; Humans; Ovarian Cysts; Ovarian Neoplasms; Teratoma
PubMed: 32911089
DOI: 10.1016/j.jmig.2020.09.001 -
Ophthalmic Plastic and Reconstructive...
Topics: Dermoid Cyst; Humans; Magnetic Resonance Imaging; Tomography, X-Ray Computed
PubMed: 32282645
DOI: 10.1097/IOP.0000000000001668 -
The Canadian Journal of Neurological... Nov 2022
Topics: Humans; Dermoid Cyst; Teratoma; Central Nervous System Cysts
PubMed: 34503588
DOI: 10.1017/cjn.2021.210 -
International Journal of Pediatric... Oct 2021The study aimed to present the accuracy of radiological diagnostics in pediatric patients with nasal dermoids and to discuss the potential factors influencing the... (Review)
Review
OBJECTIVE
The study aimed to present the accuracy of radiological diagnostics in pediatric patients with nasal dermoids and to discuss the potential factors influencing the radiological pitfalls on imaging in these cases.
MATERIAL AND METHODS
The patient's cohort included 25 surgically treated pediatric cases with nasal dermoid. The results of preoperative imaging studies were analyzed regarding intraoperative findings. A review of the literature concerning a series of cases with nasal dermoid was performed in order to evaluate the possible radiological pitfalls and the accuracy of radiological imaging. The following statistical parameters for the particular radiological tools was determined: sensitivity, specificity, predictive positive values and predictive negative values.
RESULTS
Total number of 18 CT and 14 MRI were performed. 6 out of 32 radiological examinations occurred to be inconsistent with operative findings. Potential pitfalls were identified and discussed. All the patients with false radiological results were below the age of 5 and 83% were below the age of 3 y.o. The overall sensitivity (S), specificity (SP), predictive positive value (PPV) and predictive negative value (PNV) for CT vs. MRI were 68% vs. 79%, 90% vs. 95%, 65% vs. 86% and 90% vs. 92%, respectively.
CONCLUSIONS
MRI technique characterizes with higher predictive values in terms of identifying intracranial extension of nasal dermoid on imaging. Further analysis of radiological methods' accuracy should be conducted based on the detailed data concerning age distribution. The combination of CT and MRI should become a gold standard in diagnostics of nasal dermoids in children under the age of 5.
Topics: Child; Dermoid Cyst; Humans; Magnetic Resonance Imaging; Nose Neoplasms; Radiography; Tomography, X-Ray Computed
PubMed: 34329830
DOI: 10.1016/j.ijporl.2021.110842 -
Current Pain and Headache Reports May 2020Intracranial dermoid cysts are benign, rare mass-occupying lesions of the central nervous system arising from the neuroectodermal cell lines. While rupture of...
PURPOSE OF REVIEW
Intracranial dermoid cysts are benign, rare mass-occupying lesions of the central nervous system arising from the neuroectodermal cell lines. While rupture of intracranial dermoid cysts is rare, it can present with a variety of clinical manifestations. To explore the headache manifestations among patients with ruptured intracranial dermoid cysts. To our knowledge, limited studies focusing on headache due to the intracranial dermoid cysts rupture have been published to date. A literature review was done through PubMed/Medline. Articles within the past 10 years were reviewed. Articles in languages other than English were excluded.
RECENT FINDINGS
Rupture of intracranial dermoid cysts could have various manifestations including headache, seizure, and meningitis. Depending on the location of the cyst, headache secondary to the rupture of the intracranial dermoid cysts could present in different ways. A detailed systematic literature review of headache presentations due to intracranial dermoid cysts rupture is provided.
Topics: Brain Neoplasms; Central Nervous System Cysts; Dermoid Cyst; Headache; Humans; Magnetic Resonance Imaging; Meningitis, Aseptic; Migraine Disorders; Rupture, Spontaneous; Seizures; Tomography, X-Ray Computed
PubMed: 32472229
DOI: 10.1007/s11916-020-00863-x -
International Journal of Pediatric... Dec 2020Nasal dermoid sinus cyst (NDSC) are uncommon congenital lesions in children. (Review)
Review
INTRODUCTION
Nasal dermoid sinus cyst (NDSC) are uncommon congenital lesions in children.
OBJECTIVE
To review the clinical and radiological presentation and study the surgical outcomes of this uncommon lesion.
METHOD
Retrospective chart review of all children diagnosed with nasal dermoid from 2010 to 2020 at a tertiary referral hospital in South India was executed. The medical records were reviewed for demographics, lesion characteristics, imaging, operative details, and outcomes and literature review was performed.
RESULT
A total of 25 children [Mean age 3.7 yrs (Range 2-9 yrs)] with nasal dermoid sinus cysts were treated in the last decade. While 13 presented with a sinus, 11 presented with cyst and 1 had both. The lesions mainly involved the upper third of the nose in 10 children, middle one third in 6 and upper one third in 9 children. All underwent Magnetic Resonance Imaging, in 11 Computed Tomography also was done. A flow chart of the lesion characteristics and its management has been presented. Intraoperatively intracranial extension was present in four children. The approach to intracranial extension and corresponding literature review has been presented. Follow up ranged from one to six years. (Median 3.5 yrs) and no recurrence or complication was noted.
CONCLUSION
Nasal dermoid is an uncommon congenital anomaly. Preoperative evaluation must include imaging to assess extent and rule out intracranial extension. Surgical strategy depends on whether presentation is as sinus or cyst and location and extent of lesion. All surgical approaches have a good surgical and cosmetic outcome.
Topics: Child; Child, Preschool; Dermoid Cyst; Humans; India; Neoplasm Recurrence, Local; Nose Neoplasms; Retrospective Studies; Tertiary Care Centers
PubMed: 33035807
DOI: 10.1016/j.ijporl.2020.110418 -
Clinical Otolaryngology : Official... May 2024To assess the endoscopic assisted excision of the nasoorbital dermaoid cyst.
OBJECTIVE
To assess the endoscopic assisted excision of the nasoorbital dermaoid cyst.
DESIGH
Case series.
SETTING
Zagazig univesity hospitals.
PARTICPANT
The study included patients with nasal dermoid who were operated using a local vertical incision with endoscopic assisted dissection and excision.
MAIN OUTCOME MEASURES
Complete removal, complication, recurrence.
RESULTS
In all patients, complete excision of the cyst was achieved with negligable blood loss. No recurrence was detected throughout the follow up.
CONCLUSION
Endoscopic-assisted resection of the nasal dermoid cyst appears a safe and effective approach with small incision, precise dissection and satisfactory apparent scar with with low incidence of recurrence.
Topics: Humans; Dermoid Cyst; Nose Neoplasms; Endoscopy, Gastrointestinal; Dissection; Cicatrix
PubMed: 38311981
DOI: 10.1111/coa.14134 -
Medicine Mar 2024Most of the mature teratomas are found in the ovaries. Extragonadal teratomas are extremely rare. To date, there are only a handful of reports of uterine cervical... (Review)
Review
RATIONALE
Most of the mature teratomas are found in the ovaries. Extragonadal teratomas are extremely rare. To date, there are only a handful of reports of uterine cervical teratomas documented in the English literature.
PATIENT CONCERNS
Herein we describe a rare case of a 40-year-old patient who was presented to our hospital for a cervical polypoid mass, which was finally confirmed to be mature solid teratoma in uterine cervix.
DIAGNOSES
Histological examination of the polypoid mass was found to consist of ciliated pseudostratified columnar respiratory epithelium, intestinal epithelium and smooth muscle tissue, adipose tissue and mature glial component, epidermis, and skin adnexa. Meanwhile, no history of abortion, dilatation, and curettage was present in this patient, so implantation of fetal tissue was excluded. Therefore, we make a diagnosis of uterine cervical mature teratoma.
INTERVENTIONS
Tumorectomy was performed after discovering the cervical polypoid mass.
OUTCOMES
The patient had been followed-up for next 3 months after surgery and no recurrence was documented until now.
LESSONS
Though teratomas of the uterine cervix are extremely rare, more attention should be paid on this rare but possible tumor for appropriate treatment in these patients.
Topics: Female; Pregnancy; Humans; Adult; Uterine Cervical Neoplasms; Teratoma; Cervix Uteri; Dermoid Cyst; Uterus
PubMed: 38552061
DOI: 10.1097/MD.0000000000037451 -
International Journal of Gynaecology... Jan 2023To find cumulative recurrence rate and risk factors for recurrence in young women with mature cystic teratoma (MCT).
OBJECTIVE
To find cumulative recurrence rate and risk factors for recurrence in young women with mature cystic teratoma (MCT).
METHODS
Patients aged 10-29 years with MCT confirmed by their first ovarian surgery between 2000 and 2018 were included in the study. To rule out residual lesions, only patients with no MCT-suspected lesions on imaging within 1 year after surgery were included in the study. Patients who had not undergone imaging tests from 1 year after surgery or had other findings on biopsy were excluded.
RESULTS
The present study included 372 (84.2%) patients with cystectomy and 70 (15.8%) patients with oophorectomy. The 5-year cumulative recurrence rates for each patient group were 11.2% and 20.3%, respectively. The hazard rate of recurrence was higher in the oophorectomy group than the cystectomy group within 5 years after surgery. Large tumor size (hazard ratio [HR] 2.59; 95% confidence interval [CI] 1.11-6.08) and bilaterality (HR 2.65; 95% CI 1.27-5.52) were significant predictors of recurrence in the cystectomy group.
CONCLUSION
The 5-year cumulative recurrence rate after surgery in young women with ovarian MCT was 11.2% in the cystectomy group and 20.3% in the oophorectomy group. Risk factors for recurrence after cystectomy were large tumor size and bilaterality.
Topics: Humans; Female; Teratoma; Dermoid Cyst; Ovarian Neoplasms; Ovariectomy; Retrospective Studies
PubMed: 35749581
DOI: 10.1002/ijgo.14320