-
Abdominal Radiology (New York) Nov 2022Several infections can predispose to certain malignancies in different body parts. These infections include viral, bacterial, and fungal pathogens. Imaging plays a vital... (Review)
Review
Several infections can predispose to certain malignancies in different body parts. These infections include viral, bacterial, and fungal pathogens. Imaging plays a vital role in the diagnosis, staging, and management of these neoplastic conditions. Furthermore, it can help in differentiating infection-related non-neoplastic processes that can mimic malignancies. Both radiologists and clinicians should be familiar with these conditions. This review discusses the epidemiology, pathogenesis, and imaging features of infection-related tumors.
Topics: Humans; Infections; Multimodal Imaging; Neoplasms
PubMed: 36069914
DOI: 10.1007/s00261-022-03651-w -
Current Cardiology Reports Mar 2022This review presents the current state of imaging approaches that enable real-time molecular imaging in the interventional suite and discusses the potential future use... (Review)
Review
PURPOSE OF REVIEW
This review presents the current state of imaging approaches that enable real-time molecular imaging in the interventional suite and discusses the potential future use of integrated nuclear imaging and fluoroscopy for intraprocedural guidance in the evaluation and treatment of both cardiovascular and oncological diseases.
RECENT FINDINGS
Although there are no commercially available real-time hybrid nuclear imaging devices that are approved for use in the interventional suite, prototype open gantry hybrid nuclear imaging and x-ray c-arm imaging systems and theranostic catheter for location radiotracer detection are currently undergoing development and testing by multiple groups. The integration of physiological and molecular targeted nuclear imaging for real-time delivery of targeted theranostics in the interventional laboratory may enable more personalized care for a wide variety of cardiovascular procedures and improve patient outcomes.
Topics: Fluoroscopy; Heart; Humans; Imaging, Three-Dimensional; Multimodal Imaging; Radiography, Interventional; Tomography, X-Ray Computed
PubMed: 35028819
DOI: 10.1007/s11886-022-01644-1 -
Physics in Medicine and Biology Feb 2021Photoacoustic imaging-a hybrid biomedical imaging modality finding its way to clinical practices. Although the photoacoustic phenomenon was known more than a century... (Review)
Review
Photoacoustic imaging-a hybrid biomedical imaging modality finding its way to clinical practices. Although the photoacoustic phenomenon was known more than a century back, only in the last two decades it has been widely researched and used for biomedical imaging applications. In this review we focus on the development and progress of the technology in the last decade (2011-2020). From becoming more and more user friendly, cheaper in cost, portable in size, photoacoustic imaging promises a wide range of applications, if translated to clinic. The growth of photoacoustic community is steady, and with several new directions researchers are exploring, it is inevitable that photoacoustic imaging will one day establish itself as a regular imaging system in the clinical practices.
Topics: Multimodal Imaging; Photoacoustic Techniques; Spectrum Analysis
PubMed: 33361580
DOI: 10.1088/1361-6560/abd669 -
Physics in Medicine and Biology Feb 2022Positron emission tomography (PET) respiratory motion correction has been a subject of great interest for the last twenty years, prompted mainly by the development of... (Review)
Review
Positron emission tomography (PET) respiratory motion correction has been a subject of great interest for the last twenty years, prompted mainly by the development of multimodality imaging devices such as PET/computed tomography (CT) and PET/magnetic resonance imaging (MRI). PET respiratory motion correction involves a number of steps including acquisition synchronization, motion estimation and finally motion correction. The synchronization steps include the use of different external device systems or data driven approaches which have been gaining ground over the last few years. Patient specific or generic motion models using the respiratory synchronized datasets can be subsequently derived and used for correction either in the image space or within the image reconstruction process. Similar overall approaches can be considered and have been proposed for both PET/CT and PET/MRI devices. Certain variations in the case of PET/MRI include the use of MRI specific sequences for the registration of respiratory motion information. The proposed review includes a comprehensive coverage of all these areas of development in field of PET respiratory motion for different multimodality imaging devices and approaches in terms of synchronization, estimation and subsequent motion correction. Finally, a section on perspectives including the potential clinical usage of these approaches is included.
Topics: Algorithms; Artifacts; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Motion; Movement; Multimodal Imaging; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography
PubMed: 34915465
DOI: 10.1088/1361-6560/ac43fc -
Inflammatory Bowel Diseases Sep 2020Inflammatory bowel disease (IBD) is defined by a chronic relapsing and remitting inflammation of the gastrointestinal tract, with intestinal fibrosis being a major... (Review)
Review
Inflammatory bowel disease (IBD) is defined by a chronic relapsing and remitting inflammation of the gastrointestinal tract, with intestinal fibrosis being a major complication. The etiology of IBD remains unknown, but it is thought to arise from a dysregulated and excessive immune response to gut luminal microbes triggered by genetic and environmental factors. To date, IBD has no cure, and treatments are currently directed at relieving symptoms and treating inflammation. The current diagnostic of IBD relies on endoscopy, which is invasive and does not provide information on the presence of extraluminal complications and molecular aspect of the disease. Cross-sectional imaging modalities such as computed tomography enterography (CTE), magnetic resonance enterography (MRE), positron emission tomography (PET), single photon emission computed tomography (SPECT), and hybrid modalities have demonstrated high accuracy for the diagnosis of IBD and can provide both functional and morphological information when combined with the use of molecular imaging probes. This review presents the state-of-the-art imaging techniques and molecular imaging approaches in the field of IBD and points out future directions that could help improve our understanding of IBD pathological processes, along with the development of efficient treatments.
Topics: Fibrosis; Gastrointestinal Tract; Humans; Inflammation; Inflammatory Bowel Diseases; Intestines; Molecular Imaging; Multimodal Imaging
PubMed: 32793946
DOI: 10.1093/ibd/izaa213 -
Radiologic Clinics of North America Sep 2021PET/MR imaging is in routine clinical use and is at least as effective as PET/CT for oncologic and neurologic studies with advantages with certain PET... (Review)
Review
PET/MR imaging is in routine clinical use and is at least as effective as PET/CT for oncologic and neurologic studies with advantages with certain PET radiopharmaceuticals and applications. In addition, whole body PET/MR imaging substantially reduces radiation dosages compared with PET/CT which is particularly relevant to pediatric and young adult population. For cancer imaging, assessment of hepatic, pelvic, and soft-tissue malignancies may benefit from PET/MR imaging. For neurologic imaging, volumetric brain MR imaging can detect regional volume loss relevant to cognitive impairment and epilepsy. In addition, the single-bed position acquisition enables dynamic brain PET imaging without extending the total study length which has the potential to enhance the diagnostic information from PET.
Topics: Humans; Magnetic Resonance Imaging; Multimodal Imaging; Positron-Emission Tomography; Radiopharmaceuticals; Whole Body Imaging
PubMed: 34392923
DOI: 10.1016/j.rcl.2021.05.013 -
Circulation. Cardiovascular Imaging Nov 2019Fabry disease is a lysosomal storage disease with a variety of cardiac manifestations. Although not specific for a diagnosis of Fabry disease, certain cardiac imaging... (Review)
Review
Fabry disease is a lysosomal storage disease with a variety of cardiac manifestations. Although not specific for a diagnosis of Fabry disease, certain cardiac imaging findings may be highly suggestive of the diagnosis of Fabry disease in previously undiagnosed patients or cardiac involvement for patients with a known diagnosis of Fabry disease. In this review, we explore the current applications of multimodality cardiac imaging in the diagnosis and monitoring of patients with Fabry disease. Additionally, data regarding tissue characterization by cardiac magnetic resonance imaging and novel nuclear imaging techniques and their role in evaluating phenotype development is discussed.
Topics: Diagnosis, Differential; Echocardiography; Fabry Disease; Heart Ventricles; Humans; Magnetic Resonance Imaging, Cine; Multimodal Imaging
PubMed: 31718277
DOI: 10.1161/CIRCIMAGING.119.009013 -
Chemistry (Weinheim An Der Bergstrasse,... Jan 2022Magnetic resonance imaging (MRI) is one of the most powerful imaging tools today, capable of displaying superior soft-tissue contrast. This review discusses developments... (Review)
Review
Magnetic resonance imaging (MRI) is one of the most powerful imaging tools today, capable of displaying superior soft-tissue contrast. This review discusses developments in the field of F MRI multimodal probes in combination with optical fluorescence imaging (OFI), H MRI, chemical exchange saturation transfer (CEST) MRI, ultrasonography (USG), X-ray computed tomography (CT), single photon emission tomography (SPECT), positron emission tomography (PET), and photoacoustic imaging (PAI). In each case, multimodal F MRI probes compensate for the deficiency of individual techniques and offer improved sensitivity or accuracy of detection over unimodal counterparts. Strategies for designing F MRI multimodal probes are described with respect to their structure, physicochemical properties, biocompatibility, and the quality of images.
Topics: Magnetic Resonance Imaging; Multimodal Imaging; Positron-Emission Tomography; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed
PubMed: 34705306
DOI: 10.1002/chem.202102556 -
Current Opinion in Neurology Feb 2021Retinal disease can manifest with visual symptoms similar to those which result from central nervous system disorders. We provide a framework for considering retinal... (Review)
Review
PURPOSE OF REVIEW
Retinal disease can manifest with visual symptoms similar to those which result from central nervous system disorders. We provide a framework for considering retinal causes of common visual complaints presenting to a neurology clinic.
RECENT FINDINGS
Technological advances have afforded quicker detection and a more thorough understanding of these retinal entities and are crucial to consider when evaluating visual complaints in the neurology clinic.
SUMMARY
It is essential to maintain a working knowledge of common retinal conditions that symptomatically overlap with common neurologic conditions. Furthermore, the ophthalmoscopic exam and retinal imaging modalities can both aid in the diagnosis and workup of visual complaints and neurologic disease.
Topics: Diagnostic Techniques, Ophthalmological; Humans; Multimodal Imaging; Nervous System Diseases; Neurology; Retina; Retinal Diseases
PubMed: 33278143
DOI: 10.1097/WCO.0000000000000883 -
Radiologic Clinics of North America Sep 2021This review article summarizes the clinical applications of established and emerging PET tracers in the evaluation of the 5 most common gynecologic malignancies:... (Review)
Review
This review article summarizes the clinical applications of established and emerging PET tracers in the evaluation of the 5 most common gynecologic malignancies: endometrial, ovarian, cervical, vaginal, and vulvar cancers. Emphasis is given to 2-deoxy-2-[F]fluoro-d-glucose as the most widely used and studied tracer, with additional clinical tracers also explored. The common imaging protocols are discussed, including standard dose ranges and uptake times, established roles, as well as the challenges and future directions of these imaging techniques. The key points are emphasized with images from selected cases.
Topics: Female; Fluorodeoxyglucose F18; Genital Neoplasms, Female; Humans; Magnetic Resonance Imaging; Multimodal Imaging; Positron Emission Tomography Computed Tomography; Radiopharmaceuticals
PubMed: 34392921
DOI: 10.1016/j.rcl.2021.05.011