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The Veterinary Clinics of North... May 2024
Topics: Animals; Neoplasms; Veterinary Medicine
PubMed: 38105173
DOI: 10.1016/j.cvsm.2023.12.001 -
International Journal of Radiation... Apr 2023
Topics: Humans; Radiopharmaceuticals; Radiation Oncology; Neoplasms
PubMed: 36922080
DOI: 10.1016/j.ijrobp.2022.12.024 -
Current Treatment Options in Oncology Sep 2022The COVID pandemic has transformed our approach to patient care, research, and training in cardio-oncology. While the early phases of the COVID pandemic were... (Review)
Review
The COVID pandemic has transformed our approach to patient care, research, and training in cardio-oncology. While the early phases of the COVID pandemic were exceptionally frightening, we now can reflect on the innovative changes that brought more effective and patient-centered care to our doorsteps: expansion of telemedicine, integration of digital health, wider adoption of cardiac biomarkers, consolidation, and coordination of cardio-oncology testing. Normally, it takes years for health care systems to adopt new technology or modify patient care pathways; however, COVID pushed healthcare providers and the health systems to change at warp speed. All of these innovations have improved our efficacy and provided a more "patient-centered" approach for our cardio-oncology patients. The changes we have made in cardio-oncology will likely remain well beyond the pandemic and continue to grow improving the cardiovascular care of oncology patients.
Topics: COVID-19; Humans; Medical Oncology; Neoplasms; Pandemics; SARS-CoV-2
PubMed: 35969312
DOI: 10.1007/s11864-022-00997-7 -
Current Oncology (Toronto, Ont.) Oct 2019Mutations in have been implicated in the pathogenesis of various types of cancer, and therefore antibody therapy directed against the epidermal growth factor receptor...
Mutations in have been implicated in the pathogenesis of various types of cancer, and therefore antibody therapy directed against the epidermal growth factor receptor (egfr) is increasingly being used in the management of various cancers. Currently, anti-egfr antibodies are used mainly in the management of cancers of the head and neck and metastatic colorectal cancers. Because of this increasing use, we would like to inform the oncology community in North America of a rare, but life-threatening, toxicity associated with anti-egfr antibody therapy. Although cases in white and Japanese men have been documented, we present the first known North American report of panitumumab-induced pulmonary toxicity in a white woman.
Topics: Antineoplastic Agents, Immunological; Colonic Neoplasms; ErbB Receptors; Female; Humans; Lung; Middle Aged; Panitumumab; Respiratory Distress Syndrome
PubMed: 31708664
DOI: 10.3747/co.26.5399 -
American Journal of Surgery Dec 2021
Topics: Humans; Liquid Biopsy; Mutation; Neoplasms; Surgical Oncology
PubMed: 34210398
DOI: 10.1016/j.amjsurg.2021.05.011 -
The Veterinary Clinics of North... May 2024The expanding number of specialized oncology therapeutics available in veterinary oncology can make staying updated on the most recent advances challenging. This article... (Review)
Review
The expanding number of specialized oncology therapeutics available in veterinary oncology can make staying updated on the most recent advances challenging. This article summarizes the mechanism of action, available supporting data, and clinical use of three key veterinary cancer/supportive care therapeutics: Laverdia-CA1, Canalevia-CA1, and Stelfonta. This information will help guide clinical use within your practice and can be incorporated into discussions with clients regarding the newest available options for their dogs with cancer.
Topics: Humans; Animals; Dogs; Neoplasms; Medical Oncology; Dog Diseases
PubMed: 38184436
DOI: 10.1016/j.cvsm.2023.12.003 -
Pediatric Blood & Cancer May 2021This report provides a summary of the global burden of childhood cancer morbidity and mortality, which disproportionately affects low- and middle-income countries as... (Review)
Review
This report provides a summary of the global burden of childhood cancer morbidity and mortality, which disproportionately affects low- and middle-income countries as well as low- and middle-income communities within high-income countries. We review past successes and current challenges to improving clinical pediatric radiotherapy, education, and research in these regions. The Pediatric Radiation Oncology Society Taskforce in Low- and Middle-Income Countries recently outlined specific aims: (a) to increase access and quality of radiotherapy for children and adolescents afflicted with cancer; (b) to enumerate, engage, and educate a global community of providers of childhood and adolescent radiotherapy; and (c) to create evidence establishing the outcomes of setting-specific treatment standards of care when first-world standards are not achievable. This report will improve awareness of these disparities and promote attempts to correct them.
Topics: Child; Developing Countries; Global Health; Health Services Needs and Demand; Humans; Neoplasms; Prognosis; Radiotherapy; Survival Rate
PubMed: 32743983
DOI: 10.1002/pbc.28299 -
British Journal of Cancer Jan 2022Artificial intelligence (AI) is concretely reshaping the landscape and horizons of oncology, opening new important opportunities for improving the management of cancer... (Review)
Review
Artificial intelligence (AI) is concretely reshaping the landscape and horizons of oncology, opening new important opportunities for improving the management of cancer patients. Analysing the AI-based devices that have already obtained the official approval by the Federal Drug Administration (FDA), here we show that cancer diagnostics is the oncology-related area in which AI is already entered with the largest impact into clinical practice. Furthermore, breast, lung and prostate cancers represent the specific cancer types that now are experiencing more advantages from AI-based devices. The future perspectives of AI in oncology are discussed: the creation of multidisciplinary platforms, the comprehension of the importance of all neoplasms, including rare tumours and the continuous support for guaranteeing its growth represent in this time the most important challenges for finalising the 'AI-revolution' in oncology.
Topics: Artificial Intelligence; Forecasting; Humans; Medical Oncology; Neoplasms
PubMed: 34837074
DOI: 10.1038/s41416-021-01633-1 -
Critical Reviews in Oncology/hematology Oct 2022Anatomic pathology has changed dramatically in recent years. Although the microscopic assessment of tissues and cells is and will remain the mainstay of cancer diagnosis... (Review)
Review
Anatomic pathology has changed dramatically in recent years. Although the microscopic assessment of tissues and cells is and will remain the mainstay of cancer diagnosis molecular profiling has become equally relevant. Thus, to stay abreast of the evolving landscape of today's anatomic pathology, modern pathologists must be able to master the intricate world of predictive molecular pathology. To this aim, pathologists have had to acquire additional knowledge to bridge the gap between clinicians and molecular biologists. This new role is particularly important, as cases are now collegially discussed in molecular tumor boards (MTBs). Moreover, as opposed to traditional pathologists, modern pathologists have also adamantly embraced innovation while keeping a constant eye on tradition. In this article, we depict the highlights and shadows of the upcoming "Anatomic Pathology 2.0" by placing particular emphasis on the pathologist's growing role in the management of cancer patients.
Topics: Humans; Neoplasms; Pathologists
PubMed: 35934262
DOI: 10.1016/j.critrevonc.2022.103776 -
AJNR. American Journal of Neuroradiology Jun 2022Exponential technologic advancements in imaging, high-performance computing, and artificial intelligence, in addition to increasing access to vast amounts of diverse... (Review)
Review
Exponential technologic advancements in imaging, high-performance computing, and artificial intelligence, in addition to increasing access to vast amounts of diverse data, have revolutionized the role of imaging in medicine. Radiomics is defined as a high-throughput feature-extraction method that unlocks microscale quantitative data hidden within standard-of-care medical imaging. Radiogenomics is defined as the linkage between imaging and genomics information. Multiple radiomics and radiogenomics studies performed on conventional and advanced neuro-oncology image modalities show that they have the potential to differentiate pseudoprogression from true progression, classify tumor subgroups, and predict recurrence, survival, and mutation status with high accuracy. In this article, we outline the technical steps involved in radiomics and radiogenomics analyses with the use of artificial intelligence methods and review current applications in adult and pediatric neuro-oncology.
Topics: Artificial Intelligence; Child; Diagnostic Imaging; Genomics; Humans; Neoplasms; Neurology
PubMed: 34649914
DOI: 10.3174/ajnr.A7297