-
The Journal of the American Academy of... Jul 2021Chondrosarcoma is the second most common primary bone tumor, with >90% of cases representing the primary conventional subtype. In addition to arising de novo,...
Chondrosarcoma is the second most common primary bone tumor, with >90% of cases representing the primary conventional subtype. In addition to arising de novo, conventional chondrosarcoma can arise secondary to a benign underlying lesion, such as enchondroma or osteochondroma. Symptoms are often characterized by focal, dull, aching pain to the affected region. Grade is a well-recognized prognostic factor in these tumors. Grade I lesions/atypical cartilaginous tumors rarely metastasize, rarely recur, and have a 10-year survival rate of >80%. By contrast, grade III lesions are associated with a poor prognosis with the highest local recurrence rates, a lung metastasis rate of >50%, and a 10-year survival rate of <30%. The standard treatment of high-grade conventional chondrosarcoma is complete surgical resection with wide margin. However, low-grade lesions may be amenable to curettage plus or minus adjuvant local treatment. Conventional chondrosarcoma does not respond to chemotherapy or standard radiation doses. Adjuvant treatment can be beneficial for some subtypes such as chemotherapy for dedifferentiated and mesenchymal chondrosarcoma and radiation additionally for mesenchymal chondrosarcoma. Emerging radiation technologies may also play a useful role in treating tumors in anatomically complex areas such as the spine or pelvis.
Topics: Bone Neoplasms; Chondrosarcoma; Curettage; Humans; Neoplasm Recurrence, Local; Osteochondroma; Prognosis; Retrospective Studies
PubMed: 33595238
DOI: 10.5435/JAAOS-D-20-01188 -
Cutis Nov 2021Exostosis is a type of benign bone tumor in which trabecular (spongy) bone overgrows its normal border in a nodular pattern. When the growth occurs under the nail bed,...
Exostosis is a type of benign bone tumor in which trabecular (spongy) bone overgrows its normal border in a nodular pattern. When the growth occurs under the nail bed, it is termed subungual exostosis or Dupuytren exostosis. This condition may mimic other bony abnormalities such as an osteochondroma and may present with nail deformities with or without pain. For this reason, a biopsy of the lesion is necessary to rule out a precancerous growth. In rare cases, pediatric patients may have subungual exostosis, as demonstrated in our case.
Topics: Bone Neoplasms; Child; Exostoses; Humans; Nail Diseases; Nails; Osteochondroma
PubMed: 35100532
DOI: 10.12788/cutis.0380 -
Joint Bone Spine May 2022
Topics: Bone Neoplasms; Cartilage, Articular; Humans; Osteochondroma; Soft Tissue Neoplasms
PubMed: 34971858
DOI: 10.1016/j.jbspin.2021.105321 -
Joint Bone Spine Dec 2023
Topics: Humans; Osteochondroma; Patella; Bone Neoplasms
PubMed: 37028642
DOI: 10.1016/j.jbspin.2023.105571 -
Clinics in Podiatric Medicine and... Apr 2021Bone tumors of the foot are an uncommon finding. Most tumors are found incidentally on imaging and are benign. Care must be taken although due to the aggressive nature... (Review)
Review
Bone tumors of the foot are an uncommon finding. Most tumors are found incidentally on imaging and are benign. Care must be taken although due to the aggressive nature of malignant bone tumors that can occur in the calcaneus. Malignant lesions will more commonly present with symptoms of pain and swelling. Often misdiagnosed as soft tissue injuries, it is critical to be able to diagnose and treat these lesions early. Imaging plays an important role with plain films and advanced imaging. Surgical treatments can range from curettage with grafting to amputation for more aggressive lesions.
Topics: Bone Cysts; Bone Neoplasms; Calcaneus; Chondroblastoma; Chondroma; Chondrosarcoma; Ganglion Cysts; Giant Cell Tumor of Bone; Humans; Lipoma; Osteoblastoma; Osteochondroma; Osteoma; Osteosarcoma; Sarcoma, Ewing
PubMed: 33745653
DOI: 10.1016/j.cpm.2020.12.007 -
Indian Journal of Pathology &... 2021
Topics: Adult; Bone Neoplasms; Epithelial Cells; Exostoses; Finger Injuries; Humans; Male; Nail Diseases; Osteochondroma; Skin
PubMed: 34341284
DOI: 10.4103/IJPM.IJPM_656_20 -
The Pan African Medical Journal 2019We report the case of a 40-year female patient, with no previous pathological history, presenting with right unilateral mechanical gonalgias with progressive onset,...
We report the case of a 40-year female patient, with no previous pathological history, presenting with right unilateral mechanical gonalgias with progressive onset, which increased climbing and going down stairs associated with hydarthrosis on clinical examination. After normal standard X ray, MRI showed a grease of hypertrophied Hoffa's grease with heterogeneous hyposignal on T1 (A), hypersignal on T2 with grease saturation (B), heterogeneously enhancing after gadolinium injection. The diagnosis of Hoffa's disease was made and the patient, after failure of a medical treatment, underwent arthroscopy for ablation of the Hoffa's grease with good evolution. Hoffa's disease, a cause poorly known of pain of the anterior compartment of the knee, is an acute or chronic inflammation of the infrapatellar adipose tissue. The physiopathologic theory speaks of repeated micro traumas resulting in inflammatory, hemorrhagic and fibrous changes of the adipose body of Hoffa; at the final stage of the disease osteochondroma occurs. MRI is the test of choice in the early forms. It shows poorly limited edematous infiltrate with hypersignal on T2 and hyposignal on T1, in a hypertrophic infrapatellar fat body. Treatment is based on general or local non-steroidal anti-inflammatory drugs, icing, and physiotherapy, associated with immobilization. In the case of failure of conservative treatment or of osteochondroma, arthroscopic resection is the treatment of choice.
PubMed: 31762889
DOI: 10.11604/pamj.2019.34.20.19441