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The Journal of Veterinary Medical... May 2023A 6-year-old castrated male Cavalier King Charles Spaniel was referred to the Animal Medical Center, Tokyo University of Agriculture and Technology, for examination and...
A 6-year-old castrated male Cavalier King Charles Spaniel was referred to the Animal Medical Center, Tokyo University of Agriculture and Technology, for examination and treatment of recurrent pneumothorax. Chest radiography and computed tomography showed multiple cavitary lesions in the caudal right posterior lobe. These lesions were surgically excised via thoracotomy. Subsequent histopathological examination revealed paragonimiasis. In the postoperative review, we found that the owner had fed raw deer meat to the dog four months earlier. Deer meat has attracted attention as a source of Paragonimus in humans. To our knowledge, this is the first report of Paragonimus infection in a dog due to deer meat consumption.
Topics: Animals; Dogs; Humans; Male; Deer; Dog Diseases; Meat; Paragonimiasis; Paragonimus; Tomography, X-Ray Computed
PubMed: 36948633
DOI: 10.1292/jvms.22-0443 -
Journal of Parasitic Diseases :... Sep 2021Paragonimiasis, the disease caused by , is transmitted primarily by freshwater crabs in the Philippines. Human infection has been recorded, but there is a dearth of...
Paragonimiasis, the disease caused by , is transmitted primarily by freshwater crabs in the Philippines. Human infection has been recorded, but there is a dearth of published information on the extent of infection in animal reservoirs, particularly in crabs and snails. This study aimed to investigate the infection status and risk factors of in freshwater crabs and melaniid snails collected in an endemic village along Cadacan River in Irosin, Sorsogon, where human cases of paragonimiasis were previously reported. A total of 246 freshwater crabs (118 females, 128 males) were dissected, and the gills, muscles, gonads, and viscera were examined for the presence of metacercariae; of which, 41.87% were found infected. The metacercariae were recovered from the gills (100%) and muscle tissues (7.3%) of infected crabs. Male crabs were more likely to be infected (49.22%) than female crabs (33.90%) ( < 0.05). Moreover, 70.87% of crabs showed low parasite intensity levels at ≤ 30 metacercariae/g tissue. A negative weak correlation was observed between parasite intensity and crab weight and carapace length, i.e., highly infected crabs were found to be smaller in size. Meanwhile, only 12% of the 150 melaniid snails collected were positive with cercariae with and as the most infected species. Household survey conducted revealed that some knowledge, attitudes, and practices of the locals contribute to the sustained transmission of the parasite in this endemic area. These findings revealed that is still prevalent among intermediate hosts and that some social and environmental factors contributed to the sustained parasite transmission in this endemic community.
PubMed: 34475643
DOI: 10.1007/s12639-020-01340-3 -
Medicina (Kaunas, Lithuania) Jan 2023Paragonimiasis caused by trematodes belonging to the genus is often accompanied by chronic respiratory symptoms such as cough, the accumulation of sputum, hemoptysis,...
Paragonimiasis caused by trematodes belonging to the genus is often accompanied by chronic respiratory symptoms such as cough, the accumulation of sputum, hemoptysis, and chest pain. Prolonged symptoms, including respiratory symptoms, after coronavirus disease 2019 infection (COVID-19) are collectively called post-COVID-19 conditions. Paragonimiasis and COVID-19 may cause similar respiratory symptoms. We encountered five cases of paragonimiasis in patients in Japan for whom diagnoses were delayed due to the initial characterization of the respiratory symptoms as a post-COVID-19 condition. The patients had consumed homemade drunken freshwater crabs together. One to three weeks after consuming the crabs, four of the five patients were diagnosed with probable COVID-19. The major symptoms reported included cough, dyspnea, and chest pain. The major imaging findings were pleural effusion, pneumothorax, and nodular lesions of the lung. All the patients were diagnosed with paragonimiasis based on a serum antibody test and peripheral blood eosinophilia (560-15,610 cells/μL) and were treated successfully with 75 mg/kg/day praziquantel for 3 days. Before diagnosing a post-COVID-19 condition, it is necessary to consider whether other diseases, including paragonimiasis, may explain the symptoms. Further, chest radiographic or blood tests should be performed in patients with persistent respiratory symptoms after being infected with COVID-19 to avoid overlooking the possibility of infection.
Topics: Humans; Paragonimiasis; Cough; Delayed Diagnosis; COVID-19; Chest Pain; COVID-19 Testing
PubMed: 36676761
DOI: 10.3390/medicina59010137 -
Infection, Genetics and Evolution :... Jun 2021Southeast Asian lung flukes, the causative agents of human and animal paragonimiasis, comprise at least 14 species. Of these, seven species; Paragonimus bangkokensis, P....
Genetic differentiation of Southeast Asian Paragonimus Braun, 1899 (Digenea: Paragonimidae) and genetic variation in the Paragonimus heterotremus complex examined by nuclear DNA sequences.
Southeast Asian lung flukes, the causative agents of human and animal paragonimiasis, comprise at least 14 species. Of these, seven species; Paragonimus bangkokensis, P. harinasutai, P. macrorchis, P. siamensis, P. westermani, P. heterotremus and P. pseudoheterotremus were studied. Two regions of domain 1 of taurocyamine kinase; TkD1 (exon) and TkD1Int2 (intron 2), were used as genetic markers for elucidating their genetic differentiation, genetic variation, and heterozygosity. The TkD1 region was conserved between these species but can potentially be used to differentiate all seven species. However, the TkD1Int2 region had a high level of polymorphism, which is suitable for investigation of genetic variation within or between closely related species, especially P. heterotremus and P. pseudoheterotremus as well as for a phylogenetic analyses of the genus Paragonimus. Heterozygosity was mostly observed in DNA samples extracted from adult P. heterotremus including samples taken from sputum of paragonimiasis patients, whereas DNA extracted from metacercariae was not, except in the samples from Myanmar. Our findings provide evidence of DNA recombination and incomplete lineage sorting of P. heterotremus and P. pseudoheterotremus in TkD1Int2, which suggesting gene flow between these two species.
Topics: Animals; Asia, Southeastern; Cell Nucleus; DNA, Helminth; Genetic Variation; Paragonimus
PubMed: 33577999
DOI: 10.1016/j.meegid.2021.104761 -
Parasitology International Apr 2021We encountered an outbreak of paragonimiasis among Cambodian technical intern trainees (TITs) at a food-processing factory in Fukuoka, Japan. The patients were...
We encountered an outbreak of paragonimiasis among Cambodian technical intern trainees (TITs) at a food-processing factory in Fukuoka, Japan. The patients were 20-28 years old, seven females and two males, who had been in Japan for one to four years. All of them had consumed raw or undercooked Japanese mitten crab they purchased at a local grocery store near their training place. CT images showed multiple lesions not only in the lungs but in the extrapulmonary organs as well, such as subcutaneous tissues, abdominal muscles, and mesentery, in most of the patients. Their medical records indicated that all of them acquired infection in Japan, not in Cambodia. Diagnosis was made serologically and the patients were treated with praziquantel successfully. Foreign workers and TITs are increasing in Japan so rapidly, that food borne-infections, including paragonimiasis, should be considered in people from developing countries who have exotic dietary habits.
Topics: Adult; Animals; Cambodia; Disease Outbreaks; Female; Humans; Japan; Lung; Lung Diseases, Parasitic; Male; Paragonimiasis; Paragonimus westermani; Young Adult
PubMed: 33388385
DOI: 10.1016/j.parint.2020.102279 -
The American Journal of Tropical... Nov 2023
Topics: Humans; Animals; Paragonimiasis; Pleural Effusion; Paragonimus
PubMed: 37549895
DOI: 10.4269/ajtmh.23-0301 -
The Lancet. Infectious Diseases Oct 2023
Topics: Humans; Child; Paragonimiasis; Cough; Tuberculosis, Pulmonary; Lung Diseases, Parasitic
PubMed: 37775222
DOI: 10.1016/S1473-3099(23)00273-6 -
Asian Journal of Surgery Feb 2023
Topics: Humans; Paragonimiasis; Abscess; Tomography, X-Ray Computed; Abdomen
PubMed: 35963684
DOI: 10.1016/j.asjsur.2022.07.108 -
The Korean Journal of Gastroenterology... Oct 2023In Korea, the prevalence of paragonimiasis has decreased markedly since 1970 and is now rarely encountered. Although the lung is the primary site of paragonimiasis,...
In Korea, the prevalence of paragonimiasis has decreased markedly since 1970 and is now rarely encountered. Although the lung is the primary site of paragonimiasis, ectopic infestation can occur in other sites. The central nervous system is the most commonly involved ectopic site, accounting for only approximately 1% of all paragonimiasis patients. Therefore, the liver is an extremely rare site of ectopic infestation. The authors experienced the case of a 55-year-old female with hepatic paragonimiasis who presented with abdominal colicky pain.
Topics: Female; Humans; Middle Aged; Paragonimiasis; Liver; Abdominal Pain; Abdomen; Lung
PubMed: 37876259
DOI: 10.4166/kjg.2023.090 -
Tropical Biomedicine Mar 2020Paragonimiasis is an infection caused by Paragonimus, a lung fluke and is acquired by eating raw or undercooked crustaceans containing the infective metacercariae....
Paragonimiasis is an infection caused by Paragonimus, a lung fluke and is acquired by eating raw or undercooked crustaceans containing the infective metacercariae. Herein, we report a case of paragonimiasis in a Malaysian man who presented with incidental findings from chest radiographs. Examination of his biopsied lung tissue and sputum specimen revealed Paragonimus sp. eggs, whereas stool examination showed the presence of Giardia cysts. Patient was succesfully treated with praziquantel and metronidazole respectively.
Topics: Animals; Food Contamination; Giardiasis; Humans; Incidental Findings; Lung; Malaysia; Male; Metronidazole; Middle Aged; Paragonimiasis; Paragonimus; Praziquantel; Sputum
PubMed: 33612715
DOI: No ID Found