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Journal of Hazardous Materials Jan 2022Serious threat from pesticide residues to the ecosystem and human health has become a global concern. Developing reliable methods for monitoring pesticides is a... (Review)
Review
Serious threat from pesticide residues to the ecosystem and human health has become a global concern. Developing reliable methods for monitoring pesticides is a world-wide research hotspot. Carbon dots (CDs) with excellent photostability, low toxicity, and good biocompatibility have been regarded as the potential substitutes in fabricating various optical sensors for pesticide detection. Based on the relevant high-quality publications, this paper first summarizes the current state-of-the-art of the synthetic and modification approaches of CDs. Then, a comprehensive overview is given on the recent advances of CDs-based optical sensors for pesticides over the past five years, with a particular focus on photoluminescent, electrochemiluminescent and colorimetric sensors regarding the sensing mechanisms and design principles by integrating with various recognition elements including antibodies, aptamers, enzymes, molecularly imprinted polymers, and some nanoparticles. Novel functions and extended applications of CDs as signal indicators, catalyst, co-reactants, and electrode surface modifiers, in constructing optical sensors are specially highlighted. Beyond an assessment of the performances of the real-world application of these proposed optical sensors, the existing inadequacies and current challenges, as well as future perspectives for pesticide monitoring are discussed in detail. It is hoped to provide powerful insights for the development of novel CDs-based sensing strategies with their wide application in different fields for pesticide supervision.
Topics: Carbon; Ecosystem; Humans; Pesticide Residues; Pesticides; Quantum Dots
PubMed: 34449329
DOI: 10.1016/j.jhazmat.2021.126881 -
Advances in Colloid and Interface... Dec 2021The fast developments in pesticide-loaded nanodelivery systems over the last decade have inspired many companies and research organizations to highlight potential... (Review)
Review
The fast developments in pesticide-loaded nanodelivery systems over the last decade have inspired many companies and research organizations to highlight potential applications by employing encapsulation approaches in order to protect the agricultural crops. This approach is being used to retard the indiscriminate application of conventional pesticides, as well as, to make ensure the environmental safety. This article shed light on the potential of colloidal delivery systems, particularly controlled releasing profiles of several pesticides with enhanced stability and improved solubility. Colloidal nanodelivery systems, being efficient nanoformulations, have the ability to boost up the pest-control competence for prolonged intervals thru averting the early degradation of active ingredients under severe ecofriendly circumstances. This work is thus aimed to provide critical information on the meaningful role of nanocarriers for loading of pesticides. The smart art of pesticide-loaded nanocarriers can be more fruitful owing to the use of lower amount of active ingredients with improved efficiency along with minimizing the pesticide loss. Also, the future research gaps regarding nano-pesticide formulations, such as role of nanomaterials as active ingredients are discussed briefly. In addition, this article can deliver valuable information to the readers while establishing novel pesticide-loaded nanocarriers for a wide range of applications in the agriculture sectors.
Topics: Agriculture; Drug Compounding; Nanostructures; Pesticides
PubMed: 34717205
DOI: 10.1016/j.cis.2021.102552 -
Zhongguo Zhong Yao Za Zhi = Zhongguo... Mar 2022Panax ginseng, a perennial herb, is prone to diseases and insect pests in the growth process, which are primarily prevented and treated by pesticides. However, due to...
Panax ginseng, a perennial herb, is prone to diseases and insect pests in the growth process, which are primarily prevented and treated by pesticides. However, due to the lack of standardization in the types, frequencies, and doses of pesticides, pesticide residues have become the main exogenous pollutants of P. ginseng. To explore the risk of pesticide residues in P. ginseng, this paper summarized and analyzed the common pesticide residues in P. ginseng, detection techniques, and pesticide residue limit stan-dards based on the published literature in recent years. The results revealed that the main pesticide residues in P. ginseng were organochlorine pesticides, such as tetrachloronitrobenzene, pentachloronitrobenzene, and hexachlorobenzene, and the detection techniques were dominated by gas chromatography(GC), liquid chromatography(LC), or those combined with mass spectrometry(MS). Because of the long half-life and difficulty in degradation, organochlorine pesticides have become the main factor affecting the export of P. ginseng. It is worth mentioning that P. ginseng has been classified as food in Japan, South Korea, the European Union, and other countries, and the standards of pesticide residues and limits are stricter than those in China. The quality and safety of P. ginseng are prerequisites for the efficacy of Chinese medicine and the development of traditional Chinese medicine. The formulation of scientific and effective standards for pesticide application and limits would promote the high-quality development of the P. ginseng industry.
Topics: Gas Chromatography-Mass Spectrometry; Hydrocarbons, Chlorinated; Panax; Pesticide Residues; Pesticides
PubMed: 35347939
DOI: 10.19540/j.cnki.cjcmm.20211209.101 -
International Journal of Environmental... Jan 2021Conventional banana farming is pesticide-intensive and leads to high exposure of farmworkers. Ecuador is the world's biggest exporter of bananas. In this field study in...
Conventional banana farming is pesticide-intensive and leads to high exposure of farmworkers. Ecuador is the world's biggest exporter of bananas. In this field study in 5 communities in Ecuador, we recorded potentially pesticide-associated subjective health symptoms in farmworkers and compared pesticide users to workers in organic farming. With one exception, symptom rates were always higher in the pesticide-exposed group. Significance was reached in 8 out of 19 investigated symptoms with the highest odds ratios (and smallest -values) for local irritation like skin and eye irritation (OR = 3.58, CI 1.10-11.71, and 4.10, CI 1.37-12.31, respectively) as well as systemic symptoms like dizziness (OR = 4.80, CI 1.55-14.87) and fatigue (OR = 4.96, CI 1.65-14.88). Moreover, gastrointestinal symptoms were reported more frequently by pesticide users: nausea (OR = 7.5, CI 1.77-31.77) and diarrhea (OR = 6.43, CI 1.06-30.00). The majority of farmworkers were not adequately protected from pesticide exposure. For example, only 3 of 31 farmworkers that had used pesticides recently reported using gloves and only 6 reported using masks during active spraying. Improved safety measures and a reduction in pesticide use are necessary to protect the health of banana farmworkers.
Topics: Agriculture; Ecuador; Farmers; Humans; Musa; Occupational Exposure; Pesticides
PubMed: 33514015
DOI: 10.3390/ijerph18031126 -
Environmental Research Jan 2024Pesticides are extensively used agrochemicals across the world to control pest populations. However, irrational application of pesticides leads to contamination of... (Review)
Review
Pesticides are extensively used agrochemicals across the world to control pest populations. However, irrational application of pesticides leads to contamination of various components of the environment, like air, soil, water, and vegetation, all of which build up significant levels of pesticide residues. Further, these environmental contaminants fuel objectionable human toxicity and impose a greater risk to the ecosystem. Therefore, search of methodologies having potential to detect and degrade pesticides in different environmental media is currently receiving profound global attention. Beyond the conventional approaches, Artificial Intelligence (AI) coupled with machine learning and artificial neural networks are rapidly growing branches of science that enable quick data analysis and precise detection of pesticides in various environmental components. Interestingly, nanoparticle (NP)-mediated detection and degradation of pesticides could be linked to AI algorithms to achieve superior performance. NP-based sensors stand out for their operational simplicity as well as their high sensitivity and low detection limits when compared to conventional, time-consuming spectrophotometric assays. NPs coated with fluorophores or conjugated with antibody or enzyme-anchored sensors can be used through Surface-Enhanced Raman Spectrometry, fluorescence, or chemiluminescence methodologies for selective and more precise detection of pesticides. Moreover, NPs assist in the photocatalytic breakdown of various organic and inorganic pesticides. Here, AI models are ideal means to identify, classify, characterize, and even predict the data of pesticides obtained through NP sensors. The present study aims to discuss the environmental contamination and negative impacts of pesticides on the ecosystem. The article also elaborates the AI and NP-assisted approaches for detecting and degrading a wide range of pesticide residues in various environmental and agrecultural sources including fruits and vegetables. Finally, the prevailing limitations and future goals of AI-NP-assisted techniques have also been dissected.
Topics: Humans; Pesticides; Pesticide Residues; Artificial Intelligence; Ecosystem; Nanoparticles
PubMed: 37977271
DOI: 10.1016/j.envres.2023.117601 -
Zhongguo Zhong Yao Za Zhi = Zhongguo... Mar 2022The present study counted the frequency of detection technologies and monitoring frequency of pesticide species by frequency analysis based on the 28 258 pieces of data...
The present study counted the frequency of detection technologies and monitoring frequency of pesticide species by frequency analysis based on the 28 258 pieces of data on pesticide content of Chinese medicinal materials in CNKI, calculated the detection rate and exceeding rate of different types of pesticides, and systematically analyzed the pesticide residue pollution of Chinese medicinal materials. The results showed that there were 40 types of pesticides with detection rates higher than 10%, where new pesticides such as organochlorines and nicotine accounted for 55%, and organic phosphorus, pyrethroids, and carbamates accounted for 17.5%, 15.0%, and 12.5%, respectively. Seventeen types of pesticides exceeded the standard to varying degrees, including 12 types(70.59%) with exceeding rates not higher than 5%, four types(23.53%) with exceeding rates in the range of 5%-10%, and one type(5.88%) with an exceeding rate higher than 10%. As revealed by the analysis results of the past five years, the pesticide residue pollution of Chinese medicinal materials showed a downward trend. Compared with the conditions at worst, organochlorines decreased by about 2/3 in detection rate and 47.23% in exceeding rate, carbamates by about 1/2 in detection rate and 10.78% in exceeding rate, organic phosphorus by 3/4 in detection rate and 7.22% in exceeding rate, pyrethroids by 1/2 in detection rate and 11.05% in exceeding rate, and other types by about 1/2 in detection rate but not exceeded the standard. In general, pesticide residues in Chinese medicinal materials and safety have been significantly improved. However, pesticide residues are still important factors affecting the quality and safety of Chinese medicinal materials. It is suggested to further improve the control standards of pesticide residues in Chinese medicinal materials, strengthen the monitoring of pesticides used in practical production, and promote the ecological planting mode to facilitate the high-quality development of the Chinese medicinal material industry.
Topics: China; Hydrocarbons, Chlorinated; Pesticide Residues; Pesticides; Pyrethrins
PubMed: 35347938
DOI: 10.19540/j.cnki.cjcmm.20211220.101 -
Journal of Agricultural and Food... Jun 2024Finding highly active molecular scaffold structures is always the key research content of new pesticide discovery. In the research and development of new pesticides, the... (Review)
Review
Finding highly active molecular scaffold structures is always the key research content of new pesticide discovery. In the research and development of new pesticides, the discovery of new agricultural molecular scaffold structures and new targets still faces great challenges. In recent years, quinoline derivatives have developed rapidly in the discovery of new agriculturally active molecules, especially in the discovery of fungicides. The unique quinoline scaffold has many advantages in the discovery of new pesticides and can provide innovative and feasible solutions for the discovery of new pesticides. Therefore, we reviewed the use of quinoline derivatives and their analogues as molecular scaffolds in the discovery of new pesticides since 2000. We systematically summarized the agricultural biological activity of quinoline compounds and discussed the structure-activity relationship (SAR), physiological and biochemical properties, and mechanism of action of the active compounds, hoping to provide ideas and inspiration for the discovery of new pesticides.
Topics: Quinolines; Pesticides; Structure-Activity Relationship; Drug Discovery; Molecular Structure; Animals; Fungicides, Industrial; Humans
PubMed: 38775264
DOI: 10.1021/acs.jafc.4c01582 -
Environmental Research Nov 2022Organophosphate (OP) and pyrethroid pesticides (PYR) are extensively used in agriculture, resulting in higher exposures among farmworkers. The present study reports the...
Organophosphate (OP) and pyrethroid pesticides (PYR) are extensively used in agriculture, resulting in higher exposures among farmworkers. The present study reports the occurrence of 8 urinary OP and PYR metabolites in a sample of farmworkers and residents from Sucs (n = 87), a rural township in North West Catalonia (Spain). The aim of the present study was to examine differences in urinary pesticide metabolite concentrations between occupationally-exposed (farmworkers; n = 45) and environmentally-exposed subjects (n = 42) and to assess the relationship between pesticide's exposures and occupational activities in a real-case scenario. Six OP and two PYR metabolites have been investigated, urine samples were extracted using SPE extraction and analyzed by UPLC-MS/MS. Three OP metabolites were commonly detectable in urine, namely TCPY (metabolite of chlorpyrifos), PNP (parathion) and DEAMPY (pirimiphos). Regarding pyrethroids, the two analyzed metabolites, 3-PBA and 4F-3-PBA, were detected in a high proportion of urine samples. Differences in concentrations between both groups were statistically significant for TCPY and 4F-3-PBA (Mann-Whitney U Test for independent groups, p < 0.05). In the case of TCPY, the concentrations were higher among the farmworkers, which is consistent with their occupational activity. The small differences found in DEAMPY, PNP, 3-PBA or even the significant higher concentrations of 4F-3-PBA among rural population suggest a general exposure to these compounds, even in those who do not carry an occupational activity. Specific personal protective equipment (PPE) among farmworkers, such as the use of gloves and mask during mixing, showed a decrease in the exposure levels, although the differences were not statistically significant. However, a positive association was found between the use of a cap during mixing (for PNP and 3-PBA) and during application (only for 3-PBA). However, this piece of cloth is mainly used for sun protection, and when not cleaned after the handling of pesticides, it might represent a continuous source of exposure through dermal contact. Farmworkers using tractors with cabin had statistically significant lower concentrations of DEAMPY than those using a tractor without cabin. The previous results suggest that occupational protections should be encouraged among farmworkers and other potential workers handling with pesticides.
Topics: Agriculture; Chlorpyrifos; Chromatography, Liquid; Humans; Occupational Exposure; Pesticides; Pyrethrins; Rural Population; Tandem Mass Spectrometry
PubMed: 36030920
DOI: 10.1016/j.envres.2022.114186 -
The Science of the Total Environment Mar 2024Bees carry out vital ecosystem services by pollinating both wild and economically important crop plants. However, while performing this function, bee pollinators may... (Review)
Review
Bees carry out vital ecosystem services by pollinating both wild and economically important crop plants. However, while performing this function, bee pollinators may encounter potentially harmful xenobiotics in the environment such as pesticides (fungicides, herbicides and insecticides). Understanding the key factors that influence the toxicological outcomes of bee exposure to these chemicals, in isolation or combination, is essential to safeguard their health and the ecosystem services they provide. In this regard, recent work using toxicogenomic and phylogenetic approaches has begun to identify, at the molecular level, key determinants of pesticide sensitivity in bee pollinators. These include detoxification systems that convert pesticides to less toxic forms and key residues in insecticide target-sites that underlie species-specific insecticide selectivity. Here we review this emerging body of research and summarise the state of knowledge of the molecular determinants of pesticide sensitivity in bee pollinators. We identify gaps in our knowledge for future research and examine how an understanding of the genetic basis of bee sensitivity to pesticides can be leveraged to, a) predict and avoid negative bee-pesticide interactions and facilitate the future development of pest-selective bee-safe insecticides, and b) inform traditional effect assessment approaches in bee pesticide risk assessment and address issues of ecotoxicological concern.
Topics: Bees; Animals; Pesticides; Insecticides; Phylogeny; Ecosystem; Fungicides, Industrial
PubMed: 38246392
DOI: 10.1016/j.scitotenv.2024.170174 -
The Science of the Total Environment Nov 2022To guarantee an adequate food supply for the world's growing population, intensive agriculture is necessary to ensure efficient food production. The use of pesticides... (Review)
Review
To guarantee an adequate food supply for the world's growing population, intensive agriculture is necessary to ensure efficient food production. The use of pesticides helps maintain maximum productivity in intensive agriculture by minimizing crop losses due to pests. However, pesticide contamination of surface waters constitutes a major problem as they are resistant to degradation and soluble enough to be transported in water. In recent years, all groups of pesticides defined by the World Health Organization have increased their use and, therefore, their prevalence in the different environmental compartments that can have harmful effects. Despite this effort, there is no rigorous monitoring program that quantifies and controls the toxic effects of each pesticide. However, multiple scientific studies have been published by specialized research groups in which this information is disseminated. Therefore, any attempt to systematize this information is relevant. This review offers a current overview of the presence and distribution of the most widely-used pesticides (insecticides, herbicides, and fungicides) by crop type and an evaluation of the relationships between their uses and environmental implications in Spain. The data demonstrated that there are correlations between the presence of specific pesticides used in the main crops and their presence in the environmental compartments. We have found preliminary data pointing to existing associations between specific pesticides used in the main crops and their presence in environmental compartments within different geographical areas of Spain; this should be the subject of further investigation.
Topics: Agriculture; Crops, Agricultural; Environment; Environmental Monitoring; Fungicides, Industrial; Herbicides; Pesticides
PubMed: 35835192
DOI: 10.1016/j.scitotenv.2022.157291