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BMB Reports Aug 2021In animals, proper locomotion is crucial to find mates and foods and avoid predators or dangers. Multiple sensory systems detect external and internal cues and integrate... (Review)
Review
In animals, proper locomotion is crucial to find mates and foods and avoid predators or dangers. Multiple sensory systems detect external and internal cues and integrate them to modulate motor outputs. Proprioception is the internal sense of body position, and proprioceptive control of locomotion is essential to generate and maintain precise patterns of movement or gaits. This proprioceptive feedback system is conserved in many animal species and is mediated by stretch-sensitive receptors called proprioceptors. Recent studies have identified multiple proprioceptive neurons and proprioceptors and their roles in the locomotion of various model organisms. In this review we describe molecular and neuronal mechanisms underlying proprioceptive feedback systems in C. elegans, Drosophila, and mice. [BMB Reports 2021; 54(8): 393-402].
Topics: Animals; Caenorhabditis elegans; Drosophila; Feedback, Sensory; Humans; Kinesthesis; Locomotion; Mice; Motor Activity; Motor Neurons; Postural Balance; Proprioception; Sensory Receptor Cells
PubMed: 34078529
DOI: 10.5483/BMBRep.2021.54.8.052 -
Journal of Neurophysiology Aug 2019In addition to being a prerequisite for many activities of daily living, the ability to maintain steady upright standing is a relevant model to study sensorimotor... (Review)
Review
In addition to being a prerequisite for many activities of daily living, the ability to maintain steady upright standing is a relevant model to study sensorimotor integrative function. Upright standing requires managing multimodal sensory inputs to produce finely tuned motor output that can be adjusted to accommodate changes in standing conditions and environment. The sensory information used for postural control mainly arises from the vestibular system of the inner ear, vision, and proprioception. Proprioception (sense of body position and movement) encompasses signals from mechanoreceptors (proprioceptors) located in muscles, tendons, and joint capsules. There is general agreement that proprioception signals from leg muscles provide the primary source of information for postural control. This is because of their exquisite sensitivity to detect body sway during unperturbed upright standing that mainly results from variations in leg muscle length induced by rotations around the ankle joint. However, aging is associated with alterations of muscle spindles and their neural pathways, which induce a decrease in the sensitivity, acuity, and integration of the proprioceptive signal. These alterations promote changes in postural control that reduce its efficiency and thereby may have deleterious consequences for the functional independence of an individual. This narrative review provides an overview of how aging alters the proprioceptive signal from the legs and presents compelling evidence that these changes modify the neural control of upright standing.
Topics: Aging; Humans; Leg; Muscle Spindles; Postural Balance; Proprioception; Standing Position
PubMed: 31166819
DOI: 10.1152/jn.00067.2019 -
Journal of Applied Physiology... Mar 2022Proprioception, which can be defined as the awareness of the mechanical and spatial state of the body and its musculoskeletal parts, is critical to motor actions and...
Proprioception, which can be defined as the awareness of the mechanical and spatial state of the body and its musculoskeletal parts, is critical to motor actions and contributes to our sense of body ownership. To date, clinical proprioceptive tests have focused on a person's ability to detect, discriminate, or match limb positions or movements, and reveal that the strength of the relationship between deficits in proprioception and physical function varies widely. Unfortunately, these tests fail to assess higher-level proprioceptive abilities. In this Perspective, we propose that to understand fully the link between proprioception and function, we need to look beyond traditional clinical tests of proprioception. Specifically, we present a novel framework for human proprioception assessment that is divided into two categories: low-level and high-level proprioceptive judgments. Low-level judgments are those made in a single frame of reference and are the types of judgments made in traditional proprioceptive tests (i.e., detect, discriminate or match). High-level proprioceptive abilities involve proprioceptive judgments made in a different frame of reference. For example, when a person indicates where their hand is located in space. This framework acknowledges that proprioception is complex and multifaceted and that tests of proprioception should not be viewed as interchangeable, but rather as complimentary. Crucially, it provides structure to the way researchers and clinicians can approach proprioception and its assessment. We hope this Perspective serves as the catalyst for discussion and new lines of investigation.
Topics: Hand; Humans; Movement; Proprioception; Upper Extremity
PubMed: 35142561
DOI: 10.1152/japplphysiol.00809.2021 -
BioMed Research International 2020Stretching is an important part of post ankle sprain rehabilitation, as well as an effective exercise for improving general ankle-joint performance. But the combination... (Randomized Controlled Trial)
Randomized Controlled Trial
Effectiveness of Low-Frequency Stimulation in Proprioceptive Neuromuscular Facilitation Techniques for Post Ankle Sprain Balance and Proprioception in Adults: A Randomized Controlled Trial.
Stretching is an important part of post ankle sprain rehabilitation, as well as an effective exercise for improving general ankle-joint performance. But the combination of stretching alongside low-frequency stimulation has not yet been extensively studied. Therefore, the purpose of the present randomized controlled trial was to compare the combined effects of low-frequency transcutaneous electrical nerve stimulation (TENS) with proprioceptive neuromuscular facilitation (PNF) on strength, balance, and proprioception among individuals with post ankle sprain. Sixty male subjects with lateral ankle sprain were selected and randomly allocated to three groups: group 1, group 2, and the control group (CG). Subjects in group 1 received the PNF stretching technique combined with TENS. TENS stimulation was provided using two electrodes placed 5 cm apart directly on the triceps sural muscle of the affected leg and a biphasic current with a symmetrical waveform at 50 Hz for 15 seconds, tuned for a 3-second ramp up time and a 30-second rest time with a 250-microsecond pulse duration was given with PNF stretching. Subjects in group 2 received the PNF stretching technique alone. Both group 1 and group 2 received these treatments for 4 weeks (4 days/week); follow-up assessments were administered in the third and fifth weeks. CG received no treatment; outcome measures alone were assessed. Outcome measures comprised pain, balance, flexibility, proprioception, range of motion, muscle strength, and functional limitation. A mixed-model ANOVA showed significant interaction (time and group) and the time effect for all the outcome measures ( ≤ 0.05). Group 1 (PNF-TENS) showed significant improvement for all the outcome variables compared to the other groups. The present study showed PNF stretching combined with TENS for the triceps sural muscle to trigger muscle contraction during the muscle contraction phase of the PNF stretch, compared against PNF stretching alone, produced significant improvements in ankle function for post ankle sprain subjects.
Topics: Adult; Ankle; Ankle Injuries; Humans; Male; Muscle Stretching Exercises; Postural Balance; Proprioception; Range of Motion, Articular; Transcutaneous Electric Nerve Stimulation; Young Adult
PubMed: 33029528
DOI: 10.1155/2020/9012930 -
Journal of Musculoskeletal & Neuronal... Jun 2020To examine the effect of sensorimotor and gait training on proprioception, nerve function, and muscle activation in diabetic peripheral neuropathy (DPN) patients. (Randomized Controlled Trial)
Randomized Controlled Trial
Sensorimotor and gait training improves proprioception, nerve function, and muscular activation in patients with diabetic peripheral neuropathy: a randomized control trial.
OBJECTIVES
To examine the effect of sensorimotor and gait training on proprioception, nerve function, and muscle activation in diabetic peripheral neuropathy (DPN) patients.
METHODS
Thirty-eight (25 male and 13 female) participants with DPN were selected and randomly allocated to intervention and control group. Participants in the intervention group were provided sensorimotor and gait training for eight weeks (3 days/week) along with diabetes and foot care education; participants in the control group received diabetes and foot care education only. Outcome measures involved proprioception, nerve conduction studies of peroneal and tibial nerve, and activation of lower limb muscles and multifidus while standing with eyes open and eyes closed, and treadmill walking.
RESULTS
Mixed ANOVA revealed significant time effect and time×group interaction of proprioception in all four directions (p<0.05). The conduction velocity of peroneal nerve revealed significant time effect (p=0.007) and time×group interaction (p=0.022). Interaction effect was found to be significant for medial gastrocnemius and multifidus while standing with eyes open as well as with eyes closed (p≤0.004). Only multifidus showed significant group (p=0.002) and interaction effect (p=0.003) during walking.
CONCLUSIONS
Sensorimotor and gait training is an effective tool for improvement of proprioception and nerve function. It benefits muscle activation around ankle and multifidus during postural control and walking in DPN patients. Clinical Trials Registry - India, National Institute of Medical Statistics (Indian Council of Medical Research): Registration Number - CTRI/2017/08/009328.
Topics: Aged; Diabetic Neuropathies; Exercise Therapy; Female; Humans; Male; Middle Aged; Postural Balance; Proprioception
PubMed: 32481239
DOI: No ID Found -
Journal of Musculoskeletal & Neuronal... Dec 2019This systematic review aims to determine the effectiveness of proprioceptive neuromuscular facilitation (PNF) treatment techniques in adhesive capsulitis for decreasing... (Meta-Analysis)
Meta-Analysis
This systematic review aims to determine the effectiveness of proprioceptive neuromuscular facilitation (PNF) treatment techniques in adhesive capsulitis for decreasing pain and disability and increasing range of motion (ROM) and function. A thorough, computerized search was done using database search engines by two reviewers. After meticulous scrutiny and screening of 410 studies, according to the selection criteria, 10 full-text articles were included in the review and meta-analysis. All 10 studies had undergone a methodological quality assessment by the Physiotherapy Evidence Database Scale. Meta-analysis was done for external rotation, abduction ROM and pain. The most common PNF techniques used by most of the studies were, hold-relax and contract-relax in upper limb D2 flexion, abduction, and an external rotation pattern, while some studies used scapular PNF patterns. Among the 10 included studies, nine showed that the PNF group is superior in decreasing pain and reducing disability, increasing ROM, improving function. The meta-analysis also showed a significant effect size and that the PNF is superior than conventional physical therapy in decreasing pain, increasing external rotation, and abduction ROM.
Topics: Bursitis; Humans; Physical Therapy Modalities; Proprioception; Range of Motion, Articular; Treatment Outcome
PubMed: 31789299
DOI: No ID Found -
European Journal of Physical and... Jun 2021Nonspecific neck pain is associated with chronic pain, disability, reduced cervical mobility, postural control disorders and impaired proprioceptive control. (Comparative Study)
Comparative Study Randomized Controlled Trial
BACKGROUND
Nonspecific neck pain is associated with chronic pain, disability, reduced cervical mobility, postural control disorders and impaired proprioceptive control.
AIM
The aim of this study was to compare the effectiveness of two therapeutic exercise programs (i.e. cervical proprioception and cervical mobility) in reducing pain and disability in individuals with nonspecific neck pain. We further aimed to compare the effectiveness of the two treatments in improving pressure pain threshold, cervical range of motion and head repositioning accuracy.
DESIGN
This study was designed as a randomized controlled trial.
SETTING
This study took place in a private rehabilitation clinic.
POPULATION
Forty-two participants diagnosed with nonspecific neck pain, aged 18-65 years, were randomized to a cervical mobility group (N.=22) or a proprioception group (N.=20).
METHODS
The cervical mobility group combined a passive treatment and active mobility exercises, whereas the Proprioception group combined a passive treatment and proprioceptive exercises. Pain intensity, disability, pressure pain threshold, range of motion, and head repositioning accuracy were assessed at baseline and after 10 sessions.
RESULTS
Pain intensity and disability significantly improved for both interventions (p<0.01), but such improvement was greater for pain intensity in the proprioception group than in the cervical mobility group (P<0.01). Pressure pain threshold, range of motion and head repositioning accuracy improved only in the proprioception group (P<0.01).
CONCLUSIONS
A program based on cervical proprioception exercises demonstrated to improve pain, disability, pressure pain threshold, range of motion and head repositioning accuracy in patients with nonspecific neck pain. However, a program based on cervical mobility exercises only showed to improve pain intensity and disability, while such improvement was not clinically relevant.
CLINICAL REHABILITATION IMPACT
The proprioceptive exercise program may be considered as the treatment of choice in patients with nonspecific neck pain.
Topics: Adult; Disability Evaluation; Exercise Therapy; Female; Humans; Male; Middle Aged; Neck Pain; Pain Measurement; Pain Threshold; Proprioception; Range of Motion, Articular
PubMed: 33047944
DOI: 10.23736/S1973-9087.20.06302-9 -
The Neuroscientist : a Review Journal... Dec 2019Motor control, which relies on constant communication between motor and sensory systems, is crucial for spine posture, stability and movement. Adaptions of motor control... (Review)
Review
Motor control, which relies on constant communication between motor and sensory systems, is crucial for spine posture, stability and movement. Adaptions of motor control occur in low back pain (LBP) while different motor adaption strategies exist across individuals, probably to reduce LBP and risk of injury. However, in some individuals with LBP, adapted motor control strategies might have long-term consequences, such as increased spinal loading that has been linked with degeneration of intervertebral discs and other tissues, potentially maintaining recurrent or chronic LBP. Factors contributing to motor control adaptations in LBP have been extensively studied on the motor output side, but less attention has been paid to changes in sensory input, specifically proprioception. Furthermore, motor cortex reorganization has been linked with chronic and recurrent LBP, but underlying factors are poorly understood. Here, we review current research on behavioral and neural effects of motor control adaptions in LBP. We conclude that back pain-induced disrupted or reduced proprioceptive signaling likely plays a pivotal role in driving long-term changes in the top-down control of the motor system via motor sensory cortical reorganization. In the outlook of this review, we explore whether motor control adaptations are also important for other (musculoskeletal) pain conditions.
Topics: Adaptation, Physiological; Humans; Low Back Pain; Movement; Posture; Proprioception; Sensorimotor Cortex
PubMed: 30387689
DOI: 10.1177/1073858418809074 -
Complementary Therapies in Medicine May 2022Ankle proprioception and balance impairments are usual consequences of chronic ankle instability (CAI). The impairments affect functional and sport activities and can... (Randomized Controlled Trial)
Randomized Controlled Trial
Comparative effect of walking meditation and rubber-band exercise on ankle proprioception and balance performance among persons with chronic ankle instability: A randomized controlled trial.
BACKGROUND
Ankle proprioception and balance impairments are usual consequences of chronic ankle instability (CAI). The impairments affect functional and sport activities and can lead to recurrent ankle sprain. Mind-body practice is claimed to improve ankle proprioception and balance.
OBJECTIVE
To investigate the effects of walking meditation, a mind-body practice, and compare it with the rubber-band exercise on ankle proprioception and balance among individuals with CAI.
STUDY DESIGN
A randomized controlled trial.
METHODS
Thirty-two participants with CAI aged 20.3 ± 1.8 years were randomized into three groups; 1) walking meditation (WM, n = 10), 2) Rubber-band exercise (RE, n = 11) and 3) control (n = 11). WM and RE were enrolled on a 4-week training regimen (30 min/day, 3 days/week). Before and after the training, ankle proprioception was evaluated by angular error of the ankle reposition test (AEA) at three positions, randomly, i.e., plantarflexion-5°, plantarflexion-10° and dorsiflexion-5°. Balance performance was assessed by the star excursion balance test (SEBT).
RESULTS
As adjusted by pre-training baseline, no significant difference in AEA and SEBT was found among three groups. However, after training, only the WM group revealed a significant decrease in AEA at plantarflexion-5° (p = 0.007) and plantarflexion-10° (p = 0.04) compared to the baseline. For SEBT, the WM and RE groups showed significant improvements compared to the baseline in 4 directions each (p < 0.05), while the control group improved only 2 directions (p < 0.05).
CONCLUSIONS
WM and RE groups significantly improved SEBT after 4-week training when compared to before training. Additionally, WM group also improved ankle proprioception. Therefore, WM demonstrates feasibility as a promising intervention that could be applied for balance and ankle proprioceptive rehabilitations in persons with CAI.
Topics: Adolescent; Adult; Ankle; Chronic Disease; Humans; Meditation; Postural Balance; Proprioception; Rubber; Walking; Young Adult
PubMed: 35093512
DOI: 10.1016/j.ctim.2022.102807 -
BMC Neurology Jul 2020There is growing evidence for proprioceptive dysfunction in patients with Parkinson's disease (PD). The Lee Silvermann Voice Treatment-BIG therapy (LSVT-BIG), a special...
BACKGROUND
There is growing evidence for proprioceptive dysfunction in patients with Parkinson's disease (PD). The Lee Silvermann Voice Treatment-BIG therapy (LSVT-BIG), a special training program aiming at an increase of movement amplitudes in persons with PD (PwPD), has shown to be effective on motor symptoms. LSVT-BIG is conceptionally based on improving bradykinesia, in particular the decrement of repetitive movements, by proprioceptive recalibration.
OBJECTIVE
To assess proprioceptive impairment in PwPD as compared to matched controls and to probe potential recalibration effects of the LSVT-BIG therapy on proprioception.
METHODS
Proprioceptive performance and fine motor skills were assessed in 30 PwPD and 15 matched controls. Measurements with significant impairment in PwPD were chosen as outcome parameters for a standardized 4 weeks amplitude-based training intervention (LSVT-BIG) in 11 PwPD. Proprioceptive performance served as primary outcome measure. Secondary outcome measures included the motor part of the MDS-UPDRS, the nine-hole-peg test, and a questionnaire on quality of life. Post-interventional assessments were conducted at weeks 4 and 8.
RESULTS
Compared to the control group, PwPD showed significantly larger pointing errors. After 4 weeks of LSVT-BIG therapy and even more so after an additional 4 weeks of continued training, proprioceptive performance improved significantly. In addition, quality of life improved as indicated by a questionnaire.
CONCLUSION
LSVT-BIG training may achieve a recalibration of proprioceptive processing in PwPD. Our data indicates a probable physiological mechanism of a symptom-specific, amplitude-based behavioral intervention in PwPD.
Topics: Aged; Exercise Therapy; Female; Humans; Male; Middle Aged; Parkinson Disease; Proprioception; Quality of Life
PubMed: 32652957
DOI: 10.1186/s12883-020-01858-2