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Journal of Veterinary Emergency and... Mar 2021To use a systematic, evidence-based consensus process to develop definitions for transfusion reactions in dogs and cats.
Association of Veterinary Hematology and Transfusion Medicine (AVHTM) Transfusion Reaction Small Animal Consensus Statement (TRACS). Part 1: Definitions and clinical signs.
OBJECTIVE
To use a systematic, evidence-based consensus process to develop definitions for transfusion reactions in dogs and cats.
DESIGN
Evidence evaluation of the literature was carried out for identified transfusion reaction types in dogs and cats. Reaction definitions were generated based on synthesis of human and veterinary literature. Consensus on the definitions was achieved through Delphi-style surveys. Draft recommendations were made available through industry specialty listservs and comments were incorporated.
RESULTS
Definitions with imputability criteria were developed for 14 types of transfusion reactions.
CONCLUSIONS
The evidence review and consensus process resulted in definitions that can be used to facilitate future veterinary transfusion reaction research.
Topics: Animals; Cat Diseases; Cats; Consensus; Dog Diseases; Dogs; Practice Guidelines as Topic; Transfusion Medicine; Transfusion Reaction; Veterinary Medicine
PubMed: 33792171
DOI: 10.1111/vec.13044 -
Journal of Veterinary Emergency and... Mar 2021To systematically review available evidence to develop guidelines for the prevention of transfusion reactions and monitoring of transfusion administration in dogs and...
OBJECTIVE
To systematically review available evidence to develop guidelines for the prevention of transfusion reactions and monitoring of transfusion administration in dogs and cats.
DESIGN
Evidence evaluation of the literature (identified through Medline searches through Pubmed and Google Scholar searches) was carried out for identified transfusion reaction types in dogs and cats. Evidence was evaluated using PICO (Population, Intervention, Comparison, Outcome) questions generated for each reaction type. Evidence was categorized by level of evidence (LOE) and quality (Good, Fair, or Poor). Guidelines for prevention and monitoring were generated based on the synthesis of the evidence. Consensus on the final recommendations and a proposed transfusion administration monitoring form was achieved through Delphi-style surveys. Draft recommendations and the monitoring form were made available through veterinary specialty listservs and comments were incorporated.
RESULTS
Twenty-nine guidelines and a transfusion administration monitoring form were formulated from the evidence review with a high degree of consensus CONCLUSIONS: This systematic evidence evaluation process yielded recommended prevention and monitoring guidelines and a proposed transfusion administration form. However, significant knowledge gaps were identified, demonstrating the need for additional research in veterinary transfusion medicine.
Topics: Animals; Cat Diseases; Cats; Consensus; Dog Diseases; Dogs; Practice Guidelines as Topic; Transfusion Medicine; Transfusion Reaction; Veterinary Medicine
PubMed: 33751789
DOI: 10.1111/vec.13045 -
Journal of Veterinary Emergency and... Mar 2021To systematically review available evidence to develop guidelines for diagnosis and treatment of transfusion-associated reactions in dogs and cats.
OBJECTIVE
To systematically review available evidence to develop guidelines for diagnosis and treatment of transfusion-associated reactions in dogs and cats.
DESIGN
Standardized and systemic evaluation of the literature (identified through Medline via PubMed and Google Scholar searches) was carried out for identified transfusion reaction types in dogs and cats. The available evidence was evaluated using PICO (Population, Intervention, Comparison, Outcome) questions generated for each reaction type. The evidence was categorized by level of evidence (LOE) and quality (Good, Fair, or Poor). Guidelines, diagnostic, and treatment algorithms were generated based on the evaluation of the evidence. Consensus on the final guidelines was achieved through Delphi-style surveys. Draft recommendations were disseminated through veterinary specialty listservs for review and comments, which were evaluated and integrated prior to final publication.
RESULTS
Medline via PubMed and Google Scholar databases were searched. There were 14 Population Intervention Comparison Outcome questions identified and corresponding worksheets were developed focusing on the diagnosis and treatment of transfusion-associated reactions in dogs and cats. Fourteen guidelines and four algorithms were developed with a high degree of consensus.
CONCLUSIONS
This systematic evidence evaluation process yielded recommended diagnostic and treatment algorithms for use in practice. However, significant knowledge gaps were identified, demonstrating the need for additional research in veterinary transfusion medicine.
Topics: Animals; Cat Diseases; Cats; Dog Diseases; Dogs; Practice Guidelines as Topic; Transfusion Medicine; Transfusion Reaction; Veterinary Medicine
PubMed: 33751797
DOI: 10.1111/vec.13043 -
Journal of Feline Medicine and Surgery Jan 2020Feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) infections are found in cats worldwide. Both infections are associated with a variety of clinical...
CLINICAL IMPORTANCE
Feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) infections are found in cats worldwide. Both infections are associated with a variety of clinical signs and can impact quality of life and longevity.
SCOPE
This document is an update of the 2008 American Association of Feline Practitioners' feline retrovirus management guidelines and represents current knowledge on pathogenesis, diagnosis, prevention and treatment of retrovirus infections in cats.
TESTING AND INTERPRETATION
Although vaccines are available for FeLV in many countries and for FIV in some countries, identification of infected cats remains an important factor for preventing new infections. The retrovirus status of every cat at risk of infection should be known. Cats should be tested as soon as possible after they are acquired, following exposure to an infected cat or a cat of unknown infection status, prior to vaccination against FeLV or FIV, and whenever clinical illness occurs. It might not be possible to determine a cat's infection status based on testing at a single point in time; repeat testing using different methods could be required. Although FeLV and FIV infections can be associated with clinical disease, some infected cats, especially those infected with FIV, can live for many years with good quality of life.
MANAGEMENT OF INFECTED CATS
There is a paucity of data evaluating treatments for infected cats, especially antiretroviral and immunomodulatory drugs. Management of infected cats is focused on effective preventive healthcare strategies, and prompt identification and treatment of illness, as well as limiting the spread of infection.
Topics: Animals; Cat Diseases; Cats; Retroviridae Infections; Veterinary Medicine
PubMed: 31916872
DOI: 10.1177/1098612X19895940 -
The Veterinary Clinics of North... May 2020The pathophysiology of dying and death, related to veterinary patients, has warranted less attention than normal and abnormal physiologic processes related to life... (Review)
Review
The pathophysiology of dying and death, related to veterinary patients, has warranted less attention than normal and abnormal physiologic processes related to life preservation. In addition, many veterinary patients are euthanized, which prevents observation of natural disease progression, while ameliorating suffering. Acute death in human medicine can serve as a model for understanding mechanisms of death in veterinary patients under certain conditions. The specific cause of cardiac arrest in several different models of disease elucidates end-stage disease processes. Understanding the path to death and dying in veterinary patients physiologically serves to guide best practices focused on alleviating suffering.
Topics: Animals; Death; Veterinary Medicine
PubMed: 32089326
DOI: 10.1016/j.cvsm.2019.12.003 -
Journal of the American Animal Hospital... 2020
Topics: Anesthesia; Anesthesia, General; Animal Welfare; Animals; Cat Diseases; Cats; Dog Diseases; Dogs; Hospitals, Animal; Monitoring, Physiologic; United States; Veterinary Medicine
PubMed: 32078360
DOI: 10.5326/JAAHA-MS-7055 -
The Veterinary Clinics of North... Sep 2022
Topics: Animals; Telemedicine; Veterinary Medicine
PubMed: 36058757
DOI: 10.1016/j.cvsm.2022.07.001 -
Journal of Veterinary Emergency and... 2024
Topics: Cardiopulmonary Resuscitation; Animals; Practice Guidelines as Topic; Veterinary Medicine; Heart Arrest
PubMed: 38728061
DOI: 10.1111/vec.13382 -
Parasitology International Jun 2021Antibiotics are microbial secondary metabolites and they are important for the treatment of infectious diseases. Japanese researchers have made a large contribution to... (Review)
Review
Antibiotics are microbial secondary metabolites and they are important for the treatment of infectious diseases. Japanese researchers have made a large contribution to studies of antibiotics, and they have also been important in the discovery of antiparasitic antibiotics. Satoshi Ōmura received the Nobel Prize in 2015 for the "discoveries concerning a novel therapy against infections caused by roundworm parasites", which means discovery of a new nematocidal antibiotic, avermectin. Here, I review the many antiparasitic antibiotics and their lead compounds that have been discovered for use in human and veterinary medicine.
Topics: Animals; Anthelmintics; Antiparasitic Agents; Antiprotozoal Agents; Humans; Japan; Veterinary Medicine
PubMed: 33548522
DOI: 10.1016/j.parint.2021.102298 -
Veterinary Clinical Pathology Feb 2022
Topics: Animals; Gastrointestinal Tract; Pathology, Veterinary; Veterinary Medicine
PubMed: 35170799
DOI: 10.1111/vcp.13118