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Clinical Case Reports Apr 2020Intralesional triamcinolone acetonide is an effective treatment for acanthoma fissuratum, and recognition of this condition can negate the need for unnecessary surgical...
Intralesional triamcinolone acetonide is an effective treatment for acanthoma fissuratum, and recognition of this condition can negate the need for unnecessary surgical intervention.
PubMed: 32274040
DOI: 10.1002/ccr3.2708 -
JAAD Case Reports Oct 2021
PubMed: 34522750
DOI: 10.1016/j.jdcr.2021.08.016 -
Anais Brasileiros de Dermatologia 2019Melanoacanthoma is a rare variant of seborrheic keratosis, which is notable for dark pigmentation and fast radial growth, making it difficult to distinguish from...
Melanoacanthoma is a rare variant of seborrheic keratosis, which is notable for dark pigmentation and fast radial growth, making it difficult to distinguish from melanoma. Histologically, it is characterized by proliferation of keratinocytes and dendritic melanocytes. The authors report a scalp lesion, fast growing, suspected by dermoscopy and confocal microscopy examination, with dendritic cells distributed throughout the lesion. Based on these findings, it was not possible to classify this lesion as clearly benign, so it was excised. Histopathologic evaluation and immunostain were consistent with melanoacanthoma.
Topics: Acanthoma; Aged; Dendritic Cells; Dermoscopy; Humans; Keratosis, Seborrheic; Male; Melanocytes; Microscopy, Confocal; Scalp Dermatoses; Skin Neoplasms
PubMed: 31789261
DOI: 10.1016/j.abd.2019.01.002 -
Anais Brasileiros de Dermatologia 2020The Borst-Jadassohn phenomenon is a morphological finding that consists of the presence of well-defined nests of cells located in the spiny stratum of an acanthotic...
The Borst-Jadassohn phenomenon is a morphological finding that consists of the presence of well-defined nests of cells located in the spiny stratum of an acanthotic epidermis. One of the neoplasms where this phenomenon is found is hidroacanthoma simplex. This neoplasm is considered the intraepidermal form of the eccrine poroma. Despite its benign nature, malignant transformations are reported. The present article reports a case of hidroacanthoma simplex and discusses the dermoscopy of this phenomenon.
Topics: Acanthoma; Aged, 80 and over; Biopsy; Dermoscopy; Epidermis; Female; Humans; Skin Neoplasms
PubMed: 31932162
DOI: 10.1016/j.abd.2019.03.004 -
Annals of Dermatology Dec 2020Epidermolytic acanthoma (EA) is a rare benign tumor, which usually appears as a solitary small papule. However, there are a few case reports of multiple EA, most of...
Epidermolytic acanthoma (EA) is a rare benign tumor, which usually appears as a solitary small papule. However, there are a few case reports of multiple EA, most of which occurs on the genital area. Cases of multiple EA may mimic verruca vulgaris, condyloma accuminatum, seborrheic keratosis, and bowenoid papulosis, and therefore, can be easily misdiagnosed. A 78-year-old male presented with a 2-week history of discrete, small skin-colored papules around the anus. The other case involved a 47-year-old male with a 5-year history of skin-colored papules on the scrotum. Skin biopsy of both cases revealed a well-demarcated papular lesion characterized by compact hyperkeratosis, perinuclear vacuolization, and reticular degeneration in the granular and upper spinous layer with coarse basophilic keratohyalin granules. Epidermal invagination was consistent with a cup-shaped type of EA. Both cases tested negative for human papillomavirus. We report typical cases of multiple EA, which should be considered as the differential diagnosis of small skin-colored papules in the anogenital area, to prevent the misdiagnosis.
PubMed: 33911795
DOI: 10.5021/ad.2020.32.6.512 -
Dermatology Online Journal Feb 2021Epidermolytic acanthomas (EA) are rare benign tumors of unclear etiology that present as flat, sometimes slightly keratotic, pale or whitish papules that are usually...
Epidermolytic acanthomas (EA) are rare benign tumors of unclear etiology that present as flat, sometimes slightly keratotic, pale or whitish papules that are usually asymptomatic. Not uncommonly, their clinical appearance in the anogenital area might lead to misdiagnosis as other lesions that commonly develop at this site, such as condylomata acuminata. Though mainly asymptomatic, there are also reports of EA presenting with persistent genital pruritus. We describe the first reported case of pruritic scrotal EA successfully treated with topical pimecrolimus.
Topics: Acanthoma; Dermatologic Agents; Dosage Forms; Humans; Male; Middle Aged; Pruritus; Scrotum; Skin Neoplasms; Tacrolimus; Treatment Outcome
PubMed: 33818985
DOI: No ID Found -
Postepy Dermatologii I Alergologii Jun 2020
PubMed: 32792892
DOI: 10.5114/ada.2020.96270 -
Acta Dermato-venereologica Oct 2020
Topics: Acanthoma; Ankle; Dermoscopy; Erythema; Humans; Skin Neoplasms
PubMed: 32985678
DOI: 10.2340/00015555-3651 -
Annals of Dermatology Jun 2021Clear cell acanthoma (CCA) is an uncommon, benign epithelial tumor presenting as a well-defined, slow-growing solitary nodule. The diagnosis of CCA is usually based on...
Clear cell acanthoma (CCA) is an uncommon, benign epithelial tumor presenting as a well-defined, slow-growing solitary nodule. The diagnosis of CCA is usually based on clinical and histopathological evaluation of the tumor. However, when such type of benign tumor occurs on an exposed area, a biopsy is not always the best diagnostic option since it may leave scar. The recent advent of dermoscopy has offered an accurate and non-invasive method to diagnose CCA without resorting to skin biopsy. A 40-year-old male presented with a shiny, erythematous-to-brown, flattened nodule on the left cheek. Dermoscopic examination revealed a 'string of pearls' vascular pattern, a characteristic dermoscopic feature of CCA. Under the clinical and dermoscopic impression of CCA, a 595 nm pulsed dye laser (PDL) therapy targeting the vascular tissue in the superficial dermis of the lesion was chosen for a minimally invasive treatment. After repeated sessions of PDL, an optimal cosmetic outcome was achieved and no recurrence was recorded during the follow-up period. Herein, we report a case of presumed CCA which was successfully diagnosed and treated by utilizing non-invasive modalities.
PubMed: 34079188
DOI: 10.5021/ad.2021.33.3.275 -
Dermatology Practical & Conceptual Oct 2023
Non-invasive Imaging Techniques for the Diagnosis of Clear Cell Acanthomas: Dermoscopy, Reflectance Confocal Microscopy and Line-Field Confocal Optical Coherence Tomography.
PubMed: 37992357
DOI: 10.5826/dpc.1304a231