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ACS Applied Materials & Interfaces Apr 2022Agrochemicals, which are crucial to meet the world food qualitative and quantitative demand, are compounds used to kill pests (insects, fungi, rodents, or unwanted... (Review)
Review
Agrochemicals, which are crucial to meet the world food qualitative and quantitative demand, are compounds used to kill pests (insects, fungi, rodents, or unwanted plants). Regrettably, there are some important issues associated with their widespread and extensive use (e.g., contamination, bioaccumulation, and development of pest resistance); thus, a reduced and more controlled use of agrochemicals and thorough detection in food, water, soil, and fields are necessary. In this regard, the development of new functional materials for the efficient application, detection, and removal of agrochemicals is a priority. Metal-organic frameworks (MOFs) with exceptional sorptive, recognition capabilities, and catalytical properties have very recently shown their potential in agriculture. This Review emphasizes the recent advances in the use of MOFs in agriculture through three main views: environmental remediation, controlled agrochemical release, and detection of agrochemicals.
Topics: Adsorption; Agriculture; Agrochemicals; Metal-Organic Frameworks; Water Purification
PubMed: 35393858
DOI: 10.1021/acsami.2c00615 -
Viruses Jan 2023The phage life cycle is a multi-stage process initiated by the recognition and attachment of the virus to its bacterial host. This adsorption step depends on the... (Review)
Review
The phage life cycle is a multi-stage process initiated by the recognition and attachment of the virus to its bacterial host. This adsorption step depends on the specific interaction between bacterial structures acting as receptors and viral proteins called Receptor Binding Proteins (RBP). The adsorption process is essential as it is the first determinant of phage host range and a sine qua non condition for the subsequent conduct of the life cycle. In phages belonging to the class, the capsid is attached to a tail, which is the central player in the adsorption as it comprises the RBP and accessory proteins facilitating phage binding and cell wall penetration prior to genome injection. The nature of the viral proteins involved in host adhesion not only depends on the phage morphology (i.e., myovirus, siphovirus, or podovirus) but also the targeted host. Here, we give an overview of the adsorption process and compile the available information on the type of receptors that can be recognized and the viral proteins taking part in the process, with the primary focus on phages infecting Gram-positive bacteria.
Topics: Bacteriophages; Adsorption; Gram-Positive Bacteria; Protein Binding; Viral Proteins
PubMed: 36680236
DOI: 10.3390/v15010196 -
Critical Care (London, England) Jul 2023The oXiris is a novel filter for continuous renal replacement therapy (CRRT) featuring an adsorption coating to adsorb endotoxins and remove inflammatory mediators.... (Meta-Analysis)
Meta-Analysis Review
BACKGROUND
The oXiris is a novel filter for continuous renal replacement therapy (CRRT) featuring an adsorption coating to adsorb endotoxins and remove inflammatory mediators. Given that no consensus has been reached on its potential benefits in treating sepsis, a meta-analysis was conducted to assess its impact on the clinical outcomes of this patient population.
METHODS
Eleven databases were retrieved to find relevant observational studies and randomized controlled trials. The Newcastle-Ottawa Scale and the Cochrane Risk of Bias Tool were used to assess the quality of the included studies. The Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) process was employed to assess the certainty of evidence. The 28-day mortality was the primary outcome. Secondary outcomes were 7-, 14-, and 90-day mortality, length of intensive care unit (ICU) and hospital stay, ICU and hospital mortality, norepinephrine (NE) dose, interleukin-6 (IL-6) and lactate levels, and Sequential Organ Failure Assessment (SOFA) score.
RESULTS
The meta-analysis, pooling data from 14 studies, involving 695 patients, showed significant reductions in 28-day mortality [odds ratio (OR) 0.53; 95% confidence interval (CI) 0.36-0.77, p = 0.001] and length of ICU stay [weighted mean difference (WMD) - 1.91; 95% CI - 2.56 to - 1.26, p < 0.001)] in patients with sepsis using the oXiris filter compared to other filters. Besides, the SOFA score, NE dose, IL-6 and lactate levels, and 7- and 14-day mortalities were lower in the oXiris group. However, the 90-day mortality, ICU and hospital mortality, and length of hospital stay were comparable. The quality assessment of the ten observational studies indicated intermediate to high quality (average Newcastle-Ottawa score: 7.8). However, all four randomized controlled trials (RCTs) had an unclear risk of bias. The evidence for all outcomes had a low or very low level of certainty because the original study design was mainly observational studies and the RCTs included had an unclear risk of bias and a small sample size.
CONCLUSION
The treatment with the oXiris filter during CRRT in sepsis patients may be associated with lower 28-, 7-, and 14-day mortalities, lactate levels, SOFA score, NE dose, and shorter length of ICU stay. However, due to the low or very low quality of evidence, the effectiveness of oXiris filters was still uncertain. Besides, no significant difference was observed for the 90-day mortality, ICU and hospital mortality, and length of hospital stay.
Topics: Humans; Continuous Renal Replacement Therapy; Interleukin-6; Adsorption; Sepsis; Lactates
PubMed: 37424026
DOI: 10.1186/s13054-023-04555-x -
Chemical Reviews Jul 2022Two-dimensional (2D) ultrathin silica films have the potential to reach technological importance in electronics and catalysis. Several well-defined 2D-silica structures... (Review)
Review
Two-dimensional (2D) ultrathin silica films have the potential to reach technological importance in electronics and catalysis. Several well-defined 2D-silica structures have been synthesized so far. The silica bilayer represents a 2D material with SiO stoichiometry. It consists of precisely two layers of tetrahedral [SiO] building blocks, corner connected via oxygen bridges, thus forming a self-saturated silicon dioxide sheet with a thickness of ∼0.5 nm. Inspired by recent successful preparations and characterizations of these 2D-silica model systems, scientists now can forge novel concepts for realistic systems, particularly by atomic-scale studies with the most powerful and advanced surface science techniques and density functional theory calculations. This Review provides a solid introduction to these recent developments, breakthroughs, and implications on ultrathin 2D-silica films, including their atomic/electronic structures, chemical modifications, atom/molecule adsorptions, and catalytic reactivity properties, which can help to stimulate further investigations and understandings of these fundamentally important 2D materials.
Topics: Adsorption; Catalysis; Electronics; Silicon Dioxide; Surface Properties
PubMed: 35731806
DOI: 10.1021/acs.chemrev.1c00995 -
Molecules (Basel, Switzerland) May 2023The development of supramolecular chemistry has always been accompanied by the innovation of macrocyclic hosts. The synthesis of novel macrocycles with unique structures... (Review)
Review
The development of supramolecular chemistry has always been accompanied by the innovation of macrocyclic hosts. The synthesis of novel macrocycles with unique structures and functions will bring new development opportunities for supramolecular chemistry. As a new generation of macrocyclic hosts, biphenarenes have customizable cavity sizes and diverse backbones, overcoming the limitation that the cavities of traditionally popular macrocyclic hosts are generally smaller than 10 Å. These features undoubtedly endow biphenarenes with distinguished host-guest properties, which have attracted more and more attention. In this review, the structural characteristics and molecular recognition properties of biphenarenes are summarized. In addition, the applications of biphenarenes in adsorption and separation, drug delivery, fluorescence sensing and other fields are introduced. Hopefully, this review will provide a reference for the study of macrocyclic arenes, especially biphenarenes.
Topics: Drug Delivery Systems; Adsorption
PubMed: 37298898
DOI: 10.3390/molecules28114422 -
ChemMedChem May 2022In silico adsorption of eight antimalarials that inhibit β-hematin (synthetic hemozoin) formation identified a primary binding site on the (001) face, which...
In silico adsorption of eight antimalarials that inhibit β-hematin (synthetic hemozoin) formation identified a primary binding site on the (001) face, which accommodates inhibitors via formation of predominantly π-π interactions. A good correlation (r =0.64, P=0.017) between adsorption energies and the logarithm of β-hematin inhibitory activity was found for this face. Of 53 monocyclic, bicyclic and tricyclic scaffolds, the latter yielded the most favorable adsorption energies. Five new amino-phenoxazine compounds were pursued as β-hematin inhibitors based on adsorption behaviour. The 2-substituted phenoxazines show good to moderate β-hematin inhibitory activity (<100 μM) and Plasmodium falciparum blood stage activity against the 3D7 strain. N ,N -diethyl-N -(10H-phenoxazin-2-yl)pentane-1,4-diamine (P2a) is the most promising hit with IC values of 4.7±0.6 and 0.64±0.05 μM, respectively. Adsorption energies are predictive of β-hematin inhibitory activity, and thus the in silico approach is a beneficial tool for structure-based development of new non-quinoline inhibitors.
Topics: Adsorption; Antimalarials; Hemeproteins; Plasmodium falciparum
PubMed: 35385211
DOI: 10.1002/cmdc.202200139 -
Biosensors Aug 2022Paper-based analytical devices (PADs) are highly effective tools due to their low cost, portability, low reagent accumulation, and ease of use. Molecularly imprinted... (Review)
Review
Paper-based analytical devices (PADs) are highly effective tools due to their low cost, portability, low reagent accumulation, and ease of use. Molecularly imprinted polymers (MIP) are also extensively used as biomimetic receptors and specific adsorption materials for capturing target analytes in various complex matrices due to their excellent recognition ability and structural stability. The integration of MIP and PADs (MIP-PADs) realizes the rapid, convenient, and low-cost application of molecular-imprinting analysis technology. This review introduces the characteristics of MIP-PAD technology and discusses its application in the fields of on-site environmental analysis, food-safety monitoring, point-of-care detection, biomarker detection, and exposure assessment. The problems and future development of MIP-PAD technology in practical application are also prospected.
Topics: Adsorption; Molecular Imprinting; Polymers
PubMed: 36004991
DOI: 10.3390/bios12080595 -
The Science of the Total Environment Nov 2021Nano/microplastics (NPs/MPs) and organic micropollutants are contaminants exerting serious threats to aquatic ecosystems, which are further aggravated through their... (Review)
Review
Nano/microplastics (NPs/MPs) and organic micropollutants are contaminants exerting serious threats to aquatic ecosystems, which are further aggravated through their interactions. Organic micropollutants can adsorb on the surface of NPs/MPs, enter to the digestive systems of aquatic organisms with NPs/MPs, and desorb from the surface inside the organism. Consequently, the migration behaviour of organic micropollutants is significantly affected increasing their risk to accumulate in the food chain. Therefore, understanding the adsorption interactions between NPs/MPs and organic micropollutants is critical for evaluating the fate and impact of NPs/MPs in the environment. This review article provides an overview about the role of NPs/MPs as (temporary) sinks for organic micropollutants but also as primary sources of organic micropollutants through the leaching of plastic additives. Specifically, the following aspects are discussed: adsorption/desorption mechanisms (e.g., hydrophobic partitioning interaction, surface adsorption by van der Waals forces or hydrogen bonding, and pore filling), influencing environmental factors (e.g., pH, salinity, and dissolved organic matter), leaching of plastic additives from NPs/MPs, and potential ecotoxicological effects arising from the interactions of NPs/MPs and organic micropollutants.
Topics: Adsorption; Ecosystem; Microplastics; Plastics; Water Pollutants, Chemical
PubMed: 34303986
DOI: 10.1016/j.scitotenv.2021.149140 -
Chemical Society Reviews Apr 2022Nuclear power will continue to provide energy for the foreseeable future, but it can pose significant challenges in terms of the disposal of waste and potential release... (Review)
Review
Nuclear power will continue to provide energy for the foreseeable future, but it can pose significant challenges in terms of the disposal of waste and potential release of untreated radioactive substances. Iodine is a volatile product from uranium fission and is particularly problematic due to its solubility. Different isotopes of iodine present different issues for people and the environment. I has an extremely long half-life of 1.57 × 10 years and poses a long-term environmental risk due to bioaccumulation. In contrast, I has a shorter half-life of 8.02 days and poses a significant risk to human health. There is, therefore, an urgent need to develop secure, efficient and economic stores to capture and sequester ionic and neutral iodine residues. Metal-organic framework (MOF) materials are a new generation of solid sorbents that have wide potential applicability for gas adsorption and substrate binding, and recently there is emerging research on their use for the selective adsorptive removal of iodine. Herein, we review the state-of-the-art performance of MOFs for iodine adsorption and their host-guest chemistry. Various aspects are discussed, including establishing structure-property relationships between the functionality of the MOF host and iodine binding. The techniques and methodologies used for the characterisation of iodine adsorption and of iodine-loaded MOFs are also discussed together with strategies for designing new MOFs that show improved performance for iodine adsorption.
Topics: Adsorption; Humans; Iodine; Ions; Metal-Organic Frameworks
PubMed: 35363235
DOI: 10.1039/d0cs01192d -
Journal of Colloid and Interface Science Feb 2021The adsorption of monoclonal antibodies (mAbs) on hydrophobic surfaces is known to cause protein aggregation and degradation. Therefore, surfactants, such as Poloxamer...
The adsorption of monoclonal antibodies (mAbs) on hydrophobic surfaces is known to cause protein aggregation and degradation. Therefore, surfactants, such as Poloxamer 188, are widely used in therapeutic formulations to stabilize mAbs and protect mAbs from interacting with liquid-solid interfaces. Here, the adsorption of Poloxamer 188, one mAb and their competitive adsorption on a model hydrophobic siliconized surface is investigated with neutron scattering coupled with contrast variation to determine the molecular structure of adsorbed layers for each case. Small angle neutron scattering measurements of the affinity of Poloxamer 188 to this mAb indicate that there is negligible binding at these solution conditions. Neutron reflectometry measurements of the mAb show irreversible adsorption on the siliconized surface, which cannot be washed off with neat buffer. Poloxamer 188 can be adsorbed on the surface already occupied by mAb, which enables partial removal of some adsorbed mAb by washing with buffer. The adsorption of the surfactant introduces significant conformational changes for mAb molecules that remain on the surface. In contrast, if the siliconized surface is first saturated with the surfactant, no adsorption of mAb is observed. Competitive adsorption of mAb and Poloxamer 188 from solution leads to a surface dominantly occupied with surfactant molecules, whereas only a minor amount of mAb absorbs. These findings clearly indicate that Poloxamer 188 can protect against mAb adsorption as well as modify the adsorbed conformation of previously adsorbed mAb.
Topics: Adsorption; Antibodies, Monoclonal; Neutrons; Surface Properties; Surface-Active Agents
PubMed: 33091867
DOI: 10.1016/j.jcis.2020.09.110