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The Indian Journal of Radiology &... Sep 2022Growing teratoma syndrome (GTS) is a rare entity seen following chemotherapy for metastatic nonseminomatous germ cell tumors, characterized by increase in size of...
Growing teratoma syndrome (GTS) is a rare entity seen following chemotherapy for metastatic nonseminomatous germ cell tumors, characterized by increase in size of the metastatic deposits, with normal serum tumor markers. In this article, we aim to describe the various clinicoradiological presentations of GTS treated at our center. All patients who satisfied the GTS criteria from 2001 to 2019 were included. Characteristic imaging appearances along with sites of primary lesion and metastatic disease, stage and risk stratification at diagnosis, details of chemotherapy, details of surgical treatment and histopathology, levels of tumor markers, serum β-human chorionic gonadotropin, lactate dehydrogenase, and alpha fetoprotein levels at baseline and at the end of all chemotherapy were analyzed. The significant radiological findings observed were an increase in the fat and cystic components and appearance of coarse calcifications within the lesions. Majority of the cases were male patients (87.5%) with testicular primaries and GTS transformation in nodal metastases being the most common occurrence (75%). All eight cases (100%) showed an increase in size and cystic component, whereas four out of eight cases (50%) had presence of internal septations and internal calcification. Early recognition of this entity and clinical decision making through serial radiological imaging are of utmost importance as these growing deposits are resistant to chemotherapy and radiotherapy, with complete surgical excision being the only curative and definitive treatment option.
PubMed: 36177285
DOI: 10.1055/s-0042-1744519 -
Radiology Case Reports Dec 2022Cervical teratomas are one of the rare tumors. Relating to the size of the tumor, they present as a huge neck mass with solid and cystic components. Furthermore, they...
Cervical teratomas are one of the rare tumors. Relating to the size of the tumor, they present as a huge neck mass with solid and cystic components. Furthermore, they are able to induce a hyperextension of the neck, neonatal respiratory distress, and possible malignancy. The computed tomography scan examination of this case revealed that there was a mass. It was a component of a teratoma and pathological anatomy which supported the finding. Thus, this study provided a case of a fully excised and cured cervical mature teratoma occurred in an infant. Surgical management must be undergone as thorough as feasible in order to prevent recurrences and the development of the cancer.
PubMed: 36204400
DOI: 10.1016/j.radcr.2022.08.106 -
Children (Basel, Switzerland) Nov 2020Caudal Regression Syndrome (CRS) or Caudal dysgenesis syndrome (CDS) is characterized by maldevelopment of the caudal half of the body with variable involvement of the...
Caudal Regression Syndrome (CRS) or Caudal dysgenesis syndrome (CDS) is characterized by maldevelopment of the caudal half of the body with variable involvement of the gastrointestinal, genitourinary, skeletal, and nervous systems. CRS affects 1-3 newborn infants per 100,000 live births. The prevalence in infants of diabetic mothers is reported at 1 in 350 live births which includes all the variants. A related condition is sirenomelia sequence or mermaid syndrome or symmelia and is characterized by fusion of the legs and a variable combination of the other abnormalities. The Currarino triad is a related anomaly that includes anorectal atresia, coccygeal and partial sacral agenesis, and a pre-sacral lesion such as anterior meningocele, lipoma or dermoid cyst. A multidisciplinary management approach is needed that includes rehabilitative services, and patients need a staged surgical approach.
PubMed: 33158301
DOI: 10.3390/children7110211 -
The Journal of International Advanced... Dec 2020A case of mastoid dermoid cyst (DC) was presented, and differences with cases of other temporal bone DCs were analyzed. The mastoid DC was also compared with mastoid... (Review)
Review
A case of mastoid dermoid cyst (DC) was presented, and differences with cases of other temporal bone DCs were analyzed. The mastoid DC was also compared with mastoid congenital cholesteatoma. We reported a case of a patient with mastoid DC, evaluating her clinical, radiological, and surgical findings. A review of the literature was performed to compare our findings with those reported. The preoperative radiological evaluation prompted us to plan a surgical approach to the lesion, suspecting the presence of a mastoid congenital cholesteatoma. The surgical findings were in line with the presence of a mastoid DC. Only two cases reported in the literature presented features that fulfilled the criteria of a true mastoid DC. A DC confined to the mastoid region is an extremely rare clinical entity, with asymptomatic and slow growth. Preoperative radiological differentiation between congenital cholesteatoma and DCs with atypical features can be difficult. However, surgical excision is the treatment of choice in both cases. Diagnosis is confirmed by the histological evaluation.
Topics: Cholesteatoma, Middle Ear; Dermoid Cyst; Female; Humans; Magnetic Resonance Imaging; Mastoid; Middle Aged
PubMed: 33136032
DOI: 10.5152/iao.2020.7854 -
CMAJ : Canadian Medical Association... Mar 2021
Topics: Abdominal Pain; Dermoid Cyst; Female; Humans; Narration; Ontario; Physician-Patient Relations; Quarantine; Young Adult
PubMed: 33722834
DOI: 10.1503/cmaj.210381 -
The Pan African Medical Journal 2021
Topics: Dermoid Cyst; Humans
PubMed: 34909087
DOI: 10.11604/pamj.2021.40.99.31816 -
Iranian Journal of Veterinary Research 2023Extragonadal teratoma in the head and neck region is unusual in veterinary medicine. So far, only one case of oropharyngeal teratoma has been reported in a cat.
BACKGROUND
Extragonadal teratoma in the head and neck region is unusual in veterinary medicine. So far, only one case of oropharyngeal teratoma has been reported in a cat.
CASE DESCRIPTION
In this report, a 5-month-old kitten was brought to the clinic with the complaint of difficulty breathing, food intake, and oropharyngeal mass. In clinical examination, there was a large mass, protruding from the localization included left buccal mucosa, soft palate, and extending into the oropharynx but no cranial extension was observed in CT scans. The mass was completely resected. Macroscopically, the mass measured 4.5 × 6.5 cm and contained solid and cystic areas associated with soft and hard tissue components.
FINDINGS/TREATMENT AND OUTCOME
Histopathology revealed an extragonadal solid-cystic (grade 0) oropharyngeal mature teratoma containing structures from endoderm, mesoderm, and ectoderm. After an 8-month follow-up control period, no signs of recurrence were observed.
CONCLUSION
The case was deemed worthy of being presented with its clinical, radiological, and pathological findings, and complete resection was curative for mature teratoma.
PubMed: 38799290
DOI: 10.22099/IJVR.2023.47588.6896 -
World Journal of Clinical Cases Aug 2022Rectal mature teratoma is rare and has been reported as a case report in this study. Herein, clinical presentation, magnetic resonance imaging findings, and...
BACKGROUND
Rectal mature teratoma is rare and has been reported as a case report in this study. Herein, clinical presentation, magnetic resonance imaging findings, and immunohistochemistry showed a pelvic rectal mature teratoma. The case report and the surgical treatment procedure have been discussed below.
CASE SUMMARY
A 29-year-old Chinese female showed up with over a 1-mo history of perianal mass that emerged after defecation. Physical examination indicated that the mass was 4 cm × 3 cm × 3 cm. The intraoperative procedure involved ligation of the sigmoid colon 10 cm above the upper edge of the tumor, followed by ligation of the rectum 3.5 cm above the upper edge of the tumor, and subsequent complete removal of the mass. The histopathology confirmed the mature teratoma.
CONCLUSION
The tumor can be completely removed using surgery to prevent its recurrence.
PubMed: 36158485
DOI: 10.12998/wjcc.v10.i22.7883 -
The Pan African Medical Journal 2019Dermolipoma is an ectopic skin formation with a greasy component which develops at the level of the fornix of the external canthus. Surgery for dermolipoma is not devoid...
Dermolipoma is an ectopic skin formation with a greasy component which develops at the level of the fornix of the external canthus. Surgery for dermolipoma is not devoid of dangers. There is essentially a risk of causing damage to the right external muscle and levator muscle of the upper eyelid because there is no cleavage plane between the lesion and the adjacent normal tissues to which it adheres. The anterior surface of the dermolipoma is inseparable from the temporal bulbar conjunctiva. Its posterior surface is adjacent to the right lateralis muscle and can extend up to the levator Müller's muscle complex of the upper eyelid and toward the lachrymal gland. We report the case of a 56-year old patient presenting with a yellowish white lesion of the external canthus of the right eye. The patient underwent orbital scanner in order to exclude the possibility of orbital extension and to establish the relationship with the different ocular structures. Given the aesthetic discomfort, the patient underwent surgical resection of the orbital grease in front of the orbital rim. The main differential diagnoses included conjunctival cyst, complex choristoma and dermoid cyst. Anatomopathological examination confirmed the diagnosis of dermolipoma. The postoperative course was uneventful.
PubMed: 31762890
DOI: 10.11604/pamj.2019.34.21.18120 -
Indian Journal of Thoracic and... Jan 2022Teratomas are tumors consisting of tissues derived from more than one germ cell line. Usual locations are sacrococcygeal region, intracranial, mediastinum, and gonads....
Teratomas are tumors consisting of tissues derived from more than one germ cell line. Usual locations are sacrococcygeal region, intracranial, mediastinum, and gonads. Entirely intrapulmonary teratomas, with no mediastinal component, are rarely reported. We present the case of a 37-year-old man who presented for evaluation due to persistent and progressive intermittent cough. There was no sputum or hemoptysis. Computed tomography (CT) revealed an irregular, cystic lesion in the upper lobe of his left lung, which raised suspicion for aspergilloma. The patient underwent a left thoracotomy and, after finding a completely collapsed and hypoplastic left lung almost entirely occupied by an irregular mass, a total left pneumonectomy was performed. Pathological review reported an entirely intrapulmonary mature teratoma. Intrapulmonary mature teratomas are extremely rare, although several have been reported. Trichoptysis (expectoration of hair) is a specific finding that may help distinguish this entity from mediastinal teratomas.
PubMed: 34898881
DOI: 10.1007/s12055-021-01180-7