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Revista Medica de Chile Aug 2020
Topics: Compassion Fatigue; Empathy; Health Personnel; Humans; Mental Health; Telemedicine
PubMed: 33399790
DOI: 10.4067/S0034-98872020000801219 -
PloS One 2022Intermittent fasting (IF) is an alternating pattern of restricting eating. This study evaluated mental and physical fatigue secondary to IF (daily 18-hour fast,...
Intermittent fasting (IF) is an alternating pattern of restricting eating. This study evaluated mental and physical fatigue secondary to IF (daily 18-hour fast, 7-days-a-week) in the high-fat diet (HFD)-induced male obese Sprague Dawley rats. Fifty-four rats were randomly assigned to a HFD (n = 28) or a standard diet (SD; n = 26). After six weeks, the HFD rats were divided into one of four groups: obese HFD ad libitum (OB-HFD-AL), obese HFD-IF (OB-HFD-IF), obese SD-AL (OB-SD-AL), and obese SD-IF (OB-SD-IF). Similarly, non-obese controls were grouped into HFD-AL (C-HFD-AL), non-obese HFD-IF (C-HFD-IF), non-obese SD-AL (C-SD-AL), and non-obese SD-IF (C-SD-IF). After 2 weeks of IF, mental and physical fatigue were measured using open field (OF) and novel object recognition (NOR) tests. Rats on IF gained weight at a slower pace (p<0.05) and had lower glucose levels (p<0.01) compared to the AL group. In non-obese rats, ketone levels were higher in the IF-HFD group than IF-SD (p<0.05) and AL-SD (p<0.01) animals. Obese rats exhibited elevated blood ketone levels in IF-SD conditions versus AL-SD rats (p<0.01). AL-HFD rats had higher ketone levels than AL-SD animals in both obese and non-obese groups (p<0.05). In conclusion, rats with higher blood ketone levels, whether they were on IF or AL, traveled a greater distance during OF suggesting a lack of physical fatigue. There was no significant difference between IF and AL during NOR indicating a lack of mental fatigue. Thus, IF results in reduced body weight and blood glucose levels but does not induce physical or mental fatigue.
Topics: Rats; Male; Animals; Fasting; Rats, Sprague-Dawley; Obesity; Diet, High-Fat; Ketones; Mental Fatigue
PubMed: 36322540
DOI: 10.1371/journal.pone.0275684 -
Scientific Reports Aug 2023The coronavirus disease 2019 (COVID-19) remains an epidemic worldwide. Most patients suffer residual symptoms, the so-called "Long COVID," which includes respiratory and...
The coronavirus disease 2019 (COVID-19) remains an epidemic worldwide. Most patients suffer residual symptoms, the so-called "Long COVID," which includes respiratory and neuropsychiatric symptoms. Brain Fog, one of the symptoms of Long COVID, is a major public health issue because it can impair patients' quality of life even after recovery from the disease. However, neither the pathogenesis nor the treatment of this condition remains unknown. We focused on serum ferritin levels in this study and collected information on the onset of Brain Fog through questionnaires and found that high ferritin levels during hospitalization were associated with the occurrence of Brain Fog. In addition, we excluded confounders as far as possible using propensity score analyses and found that ferritin was independently associated with Brain Fog in most of the models. We conducted phase analysis and evaluated the interaction of each phase with ferritin levels and Brain Fog. We found a positive correlation between serum ferritin levels during hospitalization and Brain Fog after COVID-19. High ferritin levels in patients with Brain Fog may reflect the contribution of chronic inflammation in the development of Brain Fog. This study provides a novel insight into the pathogenic mechanism of Brain Fog after COVID-19.
Topics: Humans; COVID-19; Post-Acute COVID-19 Syndrome; Quality of Life; Hospitalization; Mental Fatigue; Ferritins; Brain
PubMed: 37567939
DOI: 10.1038/s41598-023-40011-0 -
International Journal of Sports... Feb 2022
Topics: Humans; Mental Fatigue; Sports
PubMed: 34942596
DOI: 10.1123/ijspp.2021-0524 -
Medicine and Science in Sports and... Oct 2023Recent studies have questioned previous empirical evidence that mental fatigue negatively impacts physical performance. The purpose of this study was to investigate the... (Randomized Controlled Trial)
Randomized Controlled Trial
INTRODUCTION
Recent studies have questioned previous empirical evidence that mental fatigue negatively impacts physical performance. The purpose of this study was to investigate the critical role of individual differences in mental fatigue susceptibility by analyzing the neurophysiological and physical responses to an individualized mental fatigue task.
METHODS
In a preregistered ( https://osf.io/xc8nr/ ), randomized, within-participant design experiment, 22 recreational athletes completed a time to failure test at 80% of their peak power output under mental fatigue (individual mental effort) or control (low mental effort). Before and after the cognitive tasks, subjective feeling of mental fatigue, neuromuscular function of the knee extensors, and corticospinal excitability were measured. Sequential Bayesian analysis until it reached strong evidence in favor of the alternative hypothesis (BF 10 > 6) or the null hypothesis (BF 10 < 1/6) were conducted.
RESULTS
The individualized mental effort task resulted in a higher subjective feeling of mental fatigue in the mental fatigue condition (0.50 (95% confidence interval (CI), 0.39-0.62)) arbitrary units compared with control (0.19 (95% CI, 0.06-0.339)) arbitrary unit. However, exercise performance was similar in both conditions (control: 410 (95% CI, 357-463) s vs mental fatigue: 422 (95% CI, 367-477) s, BF 10 = 0.15). Likewise, mental fatigue did not impair knee extensor maximal force-generating capacity (BF 10 = 0.928) and did not change the extent of fatigability or its origin after the cycling exercise.
CONCLUSIONS
There is no evidence that mental fatigue adversely affects neuromuscular function or physical exercise; even if mental fatigue is individualized, computerized tasks seem not to affect physical performance.
Topics: Humans; Bayes Theorem; Exercise; Knee; Mental Fatigue; Muscle Fatigue
PubMed: 37227196
DOI: 10.1249/MSS.0000000000003221 -
Academic Psychiatry : the Journal of... Apr 2023
Topics: Humans; Compassion Fatigue; Students, Medical; Burnout, Professional; Empathy; Job Satisfaction
PubMed: 35648380
DOI: 10.1007/s40596-022-01666-5 -
Acta Psychologica Oct 2022The mechanisms underlying increased dual-task costs in the comparison of modality compatible stimulus-response mappings (e.g., visual-manual, auditory-vocal) and...
The mechanisms underlying increased dual-task costs in the comparison of modality compatible stimulus-response mappings (e.g., visual-manual, auditory-vocal) and modality incompatible mappings (e.g., visual-vocal, auditory-manual) remain elusive. To investigate whether additional control mechanisms are at work in simultaneously processing two modality incompatible mappings, we applied a transfer logic between both types of dual-task mappings in the context of a mental fatigue induction. We expected an increase in dual-task costs for both modality mappings after a fatigue induction with modality compatible tasks. In contrast, we expected an additional, selective increase in modality incompatible dual-task costs after a fatigue induction with modality incompatible tasks. We tested a group of 45young individuals (19-30 years) in an online pre-post design, in which participants were assigned to one of three groups. The two fatigue groups completed a 90-min time-on-task intervention with a dual task comprising either compatible or incompatible modality mappings. The third group paused for 90 min as a passive control group. Pre and post-session contained single and dual tasks in both modality mappings for all participants. In addition to behavioral performance measurements, seven subjective items (effort, focus, subjective fatigue, motivation, frustration, mental and physical capacity) were analyzed. Mean dual-task performance during and after the intervention indicated a practice effect instead of the presumed fatigue effect for all three groups. The modality incompatible intervention group showed a selective performance improvement for the modality incompatible mapping but no transfer to the modality compatible dual task. In contrast, the compatible intervention group showed moderately improved performance in both modality mappings. Still, participants reported increased subjective fatigue and reduced motivation after the fatigue intervention. This dynamic interplay of training and fatigue effects suggests that high control demands were involved in the prolonged performance of a modality incompatible dual task, which are separable from modality compatible dual-task demands.
Topics: Humans; Reaction Time; Psychomotor Performance; Photic Stimulation; Acoustic Stimulation; Mental Fatigue
PubMed: 36242924
DOI: 10.1016/j.actpsy.2022.103766 -
JACC. Heart Failure Jul 2020
Topics: Alert Fatigue, Health Personnel; Betacoronavirus; COVID-19; Cardiology; Cardiovascular Diseases; Coronavirus Infections; Humans; Pandemics; Pneumonia, Viral; SARS-CoV-2
PubMed: 32616168
DOI: 10.1016/j.jchf.2020.06.001 -
Biological Psychology Oct 2023To investigate the effects of sustained mental activity on perceptions of mental fatigue, cognitive performance, and autonomic response in patients with clinical burnout...
OBJECTIVE
To investigate the effects of sustained mental activity on perceptions of mental fatigue, cognitive performance, and autonomic response in patients with clinical burnout as compared to a healthy control group.
METHODS
Patients with clinical burnout (n = 30) and healthy control participants (n = 30) completed a 3-hour test session, in which they were administered a set of cognitive tests before and after an effortful cognitive task with concurrent sound exposure. Perceptions of mental fatigue and task demands (mental effort and concentration difficulties) were assessed repeatedly over the course of the test session. Heart rate variability was recorded to index autonomic response.
RESULTS
In comparison with controls, perceived mental fatigue increased earlier in the session for the clinical burnout group and did not recover following a short rest period. Throughout the session, patients rated the tasks as more demanding and showed less improvement on measures of attention and processing speed, inhibition and working memory. While autonomic responses were initially comparable, there was a unique decrease in high-frequency heart rate variability in the clinical burnout group after extended testing and exposure.
CONCLUSION
Patients with clinical burnout are affected differently than healthy controls by sustained mental activity, as reflected by ratings of perceived mental fatigue, aspects of cognitive performance and autonomic response. Further investigation into the role of autonomic regulation in relation to cognitive symptoms in clinical burnout is warranted.
Topics: Humans; Attention; Burnout, Professional; Memory, Short-Term; Mental Fatigue; Cognition
PubMed: 37598882
DOI: 10.1016/j.biopsycho.2023.108661 -
Post-acute sequelae of COVID-19 in young adults: Mental fatigue and decreased cognitive flexibility.Ideggyogyaszati Szemle Jul 2023
Post-acute sequelae of COVID-19 (PASC) describes the occurrence of persistent symptoms following COVID-19 infection. Neurological and psychiatric symptoms may include...
BACKGROUND AND PURPOSE
Post-acute sequelae of COVID-19 (PASC) describes the occurrence of persistent symptoms following COVID-19 infection. Neurological and psychiatric symptoms may include fatigue, post-exertional malaise, cognitive complaints, sensorimotor symptoms, headache, insomnia, depression, and post-traumatic stress disorder. The aim of this study was to evaluate the long-term effects of COVID-19 infection on mental fatigue and cognitive flexibility in young adults.
.METHODS
Simple random sampling method was used to enroll university students into the study between December 25 and 31, 2022. The time since active infection, central neurological findings (such as headache, dizziness, and loss of smell or taste), and the presence of lung involvement were recorded. The Mental Fatigue Scale (MFS) and the Cognitive Flexibility Inventory (CFI) were administered to all participants.
.RESULTS
The study included 102 cases and 111 controls. The case group had a significantly higher total MFS score (12.95; 9.69 respectively) (p<0.001) and significantly lower total CFI score (100.01; 109.84 respectively) (p<0.001) than the control group. The case group experienced more frequent mental fatigue than the control group (p<0.001). Among all participants, a history of COVID-19 infection was identified as a risk factor for developing mental fatigue (odds ratio/OR: 2.74). In the case group, female sex (OR: 0.38) and lung involvement (OR: 10.74) were risk factors for developing mental fatigue.
.CONCLUSION
This study demonstrates that COVID-19 infection might have long-term negative effects on cognitive health, likely due to a combination of organic and psychogenic mechanisms.
.Topics: Female; Humans; Young Adult; COVID-19; Post-Acute COVID-19 Syndrome; Headache; Mental Fatigue; Cognition
PubMed: 37471197
DOI: 10.18071/isz.76.0261