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Toxins May 2022The physiological homeostasis of the masticatory complex in short-faced patients is too robust to be disintegrated and reconstructed due to the powerful masseter muscle.... (Clinical Trial)
Clinical Trial
Can Botulinum Toxin-A Contribute to Reconstructing the Physiological Homeostasis of the Masticatory Complex in Short-Faced Patients during Occlusal Therapy? A Prospective Pilot Study.
The physiological homeostasis of the masticatory complex in short-faced patients is too robust to be disintegrated and reconstructed due to the powerful masseter muscle. This study innovatively introduced the botulinum toxin-A (BTX-A) into the field of dental occlusal treatment, providing a novel and minimally invasive therapy perspective for the two major clinical problems in these patients (low treatment efficiency and high rates of complications). In total, 10 adult patients with skeletal low angle seeking occlusal treatment (age: 27.0 ± 6.1 years; 4 males and 6 females) were administered 30−50 U of BTX-A in each masseter muscle and evaluated before and 3 months after injection based on cone-beam computed tomography (CBCT). We found a significant reduction in the thickness of the masseter muscle (MMT) (p < 0.0001). With regards to occlusion, we found a significant increase in the height of the maxillary second molar (U7-PP) (p < 0.05) with significantly flattened occlusal curves (the curve of Spee [COS] (p < 0.01), and the curve of Wilson [COW] (p < 0.05)). Furthermore, the variations in the temporomandibular joint exhibited a significant reduction in the anterior joint space (AJS) (p < 0.05) and superior joint space (SJS) (p < 0.05). In addition, the correlation analysis of the masticatory complex provided the basis for the following multiple regression equation: MMT = 10.08 − 0.11 COW + 2.73 AJS. The findings from our pilot study indicate that BTX-A, as a new adjuvant treatment attempt of occlusal therapy for short-faced patients, can provide a more favorable muscular environment for subsequent occlusal therapy through the adjustment of the biting force and may contribute to the reconstruction of healthier homeostasis of the masticatory complex. However, further research is required to establish the reliability and validity of these findings.
Topics: Adult; Botulinum Toxins, Type A; Female; Homeostasis; Humans; Male; Pilot Projects; Prospective Studies; Reproducibility of Results
PubMed: 35737035
DOI: 10.3390/toxins14060374 -
The European Journal of Prosthodontics... Nov 2022To compare the clinical performance of direct and indirect cusp covering restorations in endodontically treated molars (ETMs). Eighteen ETMs in sixteen patients were... (Randomized Controlled Trial)
Randomized Controlled Trial
To compare the clinical performance of direct and indirect cusp covering restorations in endodontically treated molars (ETMs). Eighteen ETMs in sixteen patients were randomly assigned into one of the two study groups:Group 1 (SFCRs) direct composite restorations with a short fiber-reinforced base, and Group 2 (GCEs) indirect glass-ceramic endocrowns. Eleven teeth were allocated to Group 1 and seven teeth to Group 2. Restorations were prepared in the student clinic between November 2012 and January 2015, and were evaluated at baseline and after 4.0 years according to modified USPHS criteria. The number of visits required for fabrication and maintenance of restorations were also compared. Two-way ANOVA was used to evaluate the differences between the groups (p=0.05). One SFCR and one GCE were lost due to secondary caries and endodontic complications, resulting in a 4-year survival rate of 90.9% and 85.7% respectively. Two SFCRs required minor grinding and polishing due to chipping or gloss loss, and two SFCRs needed repair due to secondary caries or loss of proximal contact. One GCE required occlusal adjustment. GCEs showed smoother surface texture and better-preserved anatomic morphology. SFCRs required more maintenance, were simpler to produce, needed usually one visit and repairs were easier to perform.
Topics: Humans; Composite Resins; Ceramics; Molar; Tooth, Nonvital; Dental Restoration Failure; Dental Restoration, Permanent
PubMed: 35438265
DOI: 10.1922/EJPRD_2333Bijelic-Donova12 -
Annals of African Medicine 2022The orientation of the occlusal plane forms the basis for the arrangement of teeth conducive to satisfactory esthetics and function, making it one of the most important...
INTRODUCTION
The orientation of the occlusal plane forms the basis for the arrangement of teeth conducive to satisfactory esthetics and function, making it one of the most important clinical procedures in prosthodontic rehabilitation. This study aimed to analyze and compare the vertical distance between the anterior attachment of lingual frenum (AALF) and the incisal edge of mandibular central incisors among three races in Malaysia.
MATERIALS AND METHODS
The sample consisted of 63 dentate subjects (21 Malays, 21 Chinese, and 21 Indians) who were chosen based on the inclusion criteria. Two models were made using irreversible hydrocolloid impressions, and an average of the value was obtained. Lingual frenum was recorded in function. Casts were fabricated with dental stone. AALF was marked and the vertical distance was measured using a caliper.
RESULTS
In Malays, the mean and standard deviation of the vertical distance were 14.2 ± 0.9 mm, with a range of 12.3-16.0 mm; in Chinese were 14.4 ± 0.9 mm, with a range of 12.0-16.9 mm; and in Indians were 15.1 ± 1.0 mm, with a range of 13.0-17.2 mm. The difference among the three races regarding the distance between AALF and the incisal edge of mandibular central incisors was statistically significant (P < 0.05). Among the three races, Malays and Indians have the greatest mean difference.
CONCLUSION
According to the results of the current study, the distance between AALF and the incisal edge of mandibular central incisors might be a proper criterion for the initial adjustment of occlusal rims. The values obtained from three different races were significantly different from one another, hence a different range of values was used to establish occlusal height for different races.
Topics: Humans; Dental Occlusion; Mandible; Incisor; Malaysia
PubMed: 36412348
DOI: 10.4103/aam.aam_174_21 -
BMC Oral Health Feb 2024This study aims to analyze the longitudinal variation of occlusal force distribution prior to and after fixed restoration for molar full-crowns with T-SCAN III which...
BACKGROUND
This study aims to analyze the longitudinal variation of occlusal force distribution prior to and after fixed restoration for molar full-crowns with T-SCAN III which provide reference for occlusal adjustment and long-term maintenance.
METHODS
We enrolled a total of 20 patients who received conventional restorative treatment for molars. The occlusion examination was conducted in 3 stages (before placement, immediately after placement, and 3 months after placement) using T-SCAN III (Tekscan South Boston, MA, USA, 10.0) to examine and measure the occlusal contact areas of the full dentition.
RESULTS
The results indicated that the occlusal force distribution in the molar region of the patients changed before and after the fixed restoration, but the percentages of occlusal force in the dental arch of the molar did not differ significantly before and after the restoration (P > 0.05). Three months after the fixed restoration, the percentage of occlusal force in the restored dental arches of lateral teeth increased significantly (P < 0.05).
CONCLUSION
The results of this study indicated that the occlusal forces of the patients changed with tooth movement and adaptation, which is mainly reflected in the increasing occlusal force. Quantitative occlusal force analysis using T-SCAN III occlusal analyzer can provide more objective and accurate data to effectively guide clinical occlusion adjustments.
Topics: Humans; Dental Occlusion; Bite Force; Molar; Crowns; Dentures
PubMed: 38388920
DOI: 10.1186/s12903-024-04014-1 -
BMC Oral Health Dec 2019The purpose of this prospective clinical study was to evaluate clinical results of the passive fit of the substructure in the Toronto bridge and the chipping or...
BACKGROUND
The purpose of this prospective clinical study was to evaluate clinical results of the passive fit of the substructure in the Toronto bridge and the chipping or delamination of the ceramic veneering on the zirconia-support, after 5 years, in nine patients rehabilitated with zirconia crowns cemented on titanium bars using CAD/CAM technology.
METHODS
A total of nine healthy patient fully edentulous in the upper and lower jaws with non-contributory past medical anamnesis needing full fixed total prosthesis maxilla and mandible were included in this clinical study, where a total 9 mandibles and 9 jaws were treated. The inclusion criteria in order for a patient to participate in the study were: a signed consent form, fully edentulous in the upper and lower jaws, required a full fixed total prosthesis restoration. The exclusion criteria were age limitation of less than 18 years old, chemotherapy, head and neck radiation therapy, diabetes or periodontal disease, smoking and severe illness. All patients received zirconia crowns cemented on titanium bars using CAD/CAM technology. The primary outcome of this study was to examine the survival rate of the zirconia crowns cemented on titanium bars using CAD/CAM technology during the observation period. Any chipping or delamination of the zirconia crowns of the restorations was considered as failure. The secondary outcome was to evaluate the passive fit of the substructure on the implants, loose of occlusal screws, implant survival and satisfactory occlusion.
RESULTS
In 5 years of follow-up no evidence of chipping or delamination of the ceramic veneering on the zirconia crown supported were observed. Fifteen finished protesis (93.75%) showed satisfactory occlusion and only one case (6.25%) required significant occlusal adjustment. During the first year recall all bars were stable (100%) no mobility of protheses was recorded. After 5 years all bars were stable (100%) and no mobility of protheses was recorded.
CONCLUSION
The computerized workflow for the process of building bar and prosthesis ensures reproducible results and excellent adaptation and passive insertion of them, as well as conditions for avoiding mechanical complications and guarantees stability of screw-implant abutments.
Topics: Adolescent; Aged; Computer-Aided Design; Crowns; Dental Prosthesis Design; Dental Prosthesis, Implant-Supported; Dental Restoration Failure; Female; Follow-Up Studies; Humans; Male; Middle Aged; Prospective Studies; Titanium; Zirconium
PubMed: 31856799
DOI: 10.1186/s12903-019-0988-x -
Journal of Orthodontics Dec 2021This study explored the association between history of orthodontic treatment and changes in self-esteem among British adolescents.
OBJECTIVE
This study explored the association between history of orthodontic treatment and changes in self-esteem among British adolescents.
DESIGN
Birth cohort study.
SETTING
United Kingdom.
PARTICIPANTS
Data from 2600 participants of the British Cohort Study were analysed.
METHODS
Participants completed the Lawrence Self-Esteem Questionnaire (LAWSEQ) at the ages of 10 and 16 years. The change in LAWSEQ score over six years was the outcome. Participants were divided into two groups according to parental reports of orthodontic treatment at the same ages. The association between history of orthodontic treatment and six-year changes in LAWSEQ score was tested in linear regression models adjusting for demographic factors (adolescents' sex and ethnicity), family socioeconomic status (parental social class and mothers' education), perceived orthodontic treatment need and baseline LAWSEQ score.
RESULTS
According to parental reports, 8% of participants had a history of orthodontic treatment. The mean LAWSEQ score at baseline was 13.7 (95% confidence interval [CI] 13.6-13.9) and increased significantly over time by 1.7 units (95% CI 1.5-1.9). Orthodontic treatment history was positively, albeit not significantly, associated with change in LAWSEQ score (coefficient: 0.08, 95% CI -0.56 to 0.72). The direction of the association reversed but remained non-significant after adjustment for all confounders (coefficient: -0.19; 95% CI -0.68 to 0.30). Improvements in self-esteem were positively associated with mothers' education (coefficient: 0.85; 95% CI 0.09-1.61) and negatively associated with self-esteem at baseline (coefficient -0.79; 95% CI -0.82 to -0.75).
CONCLUSION
This six-year longitudinal study provided no evidence for an association between history of orthodontic treatment and changes in self-esteem during adolescence.
Topics: Adolescent; Birth Cohort; Child; Cohort Studies; Humans; Longitudinal Studies; Malocclusion; Orthodontics, Corrective; Self Concept
PubMed: 33860695
DOI: 10.1177/14653125211006113 -
Dental Research Journal 2023Horizontal condylar guidance (HCG) is registered by protrusive interocclusal records but in nonarcon articulators, these records can affect the accuracy. The present...
BACKGROUND
Horizontal condylar guidance (HCG) is registered by protrusive interocclusal records but in nonarcon articulators, these records can affect the accuracy. The present study aimed to evaluate the effect of a novel rotation coordinating device (RCD) on condylar guidance setting with protrusive interocclusal records.
MATERIALS AND METHODS
The study was designed as a comparative investigation. Stone maxillary and mandibular casts were mounted on a fully adjustable instrument as the patient. Duplicate casts were mounted on an arcon and a nonarcon articulator with corresponding face bow records and in maximum intercuspation relation. Five different condylar guidance inclinations for both sides (20°, 30°, 40°, 50°, and 60°) were set on the fully adjustable instrument and 16 protrusive interocclusal records were established at each setting. HCG was set for arcon, nonarcon articulators, and nonarcon articulators with RCD. Data were analyzed using one-sample -test to compare with actual HCG and one-way analysis of variance ( =0.05).
RESULTS
Mean HCG for studied articulators was 35.40 for arcon, 30.31 for nonarcon without RCD, and 35.61 for nonarcon with RCD which were significantly different from actual HCG ( < 0.05). HCG of the nonarcon with RCD showed no significant difference with arcon articulator ( = 0.71) while both were significantly different from nonarcon without RCD ( < 0.001).
CONCLUSION
"The RCD" compensates the condylar guidance inclination difference between arcon and nonarcon articulators. The device precisely transfers the hinge movement of the upper member of the articulator to the condylar track.
PubMed: 38020259
DOI: No ID Found -
International Journal of Environmental... Oct 2022In obstructive sleep apnoea (OSA), treatment with mandibular advancement devices (MADs) reduces patients' Apnoea-Hypopnoea index (AHI) scores and improves their...
BACKGROUND
In obstructive sleep apnoea (OSA), treatment with mandibular advancement devices (MADs) reduces patients' Apnoea-Hypopnoea index (AHI) scores and improves their sleepiness and quality of life. MADs are non-invasive alternatives for patients who cannot tolerate traditional continuous positive airway pressure (CPAP) therapy. The variability of responses to these devices makes it necessary to search for predictors of success. The aim of our study was to evaluate the presence of mandibular torus as a predictor of MAD efficacy in OSA and to identify other potential cephalometric factors that could influence the response to treatment.
METHODS
This was a retrospective cohort study. The study included 103 patients diagnosed of OSA who met the criteria for initiation of treatment with MAD. Structural variables were collected (cephalometric and the presence or absence of mandibular torus). Statistical analysis was performed to evaluate the existence of predictive factors for the efficacy of MADs.
RESULTS
A total of 103 patients who were consecutively referred for treatment with MAD were included (89.3% men); the mean age of the participants was 46.3 years, and the mean AHI before MAD was 31.4 (SD 16.2) and post- MAD 11.3 (SD 9.2). Thirty-three percent of patients had mandibular torus. Torus was associated with a better response (odds ratio (OR) = 2.854 ( = 0.035)) after adjustment for sex, age, body mass index (BMI; kg/m), the angle formed by the occlusal plane to the sella-nasion plane (OCC plane to SN), overinjection, and smoking. No cephalometric predictors of efficacy were found that were predictive of MAD treatment success.
CONCLUSIONS
The presence of a mandibular torus practically triples the probability of MAD success. This is the simplest examination with the greatest benefits in terms of the efficacy of MAD treatment for OSA.
Topics: Male; Humans; Middle Aged; Female; Mandibular Advancement; Occlusal Splints; Quality of Life; Retrospective Studies; Sleep Apnea, Obstructive; Treatment Outcome
PubMed: 36361031
DOI: 10.3390/ijerph192114154 -
Scientific Reports Jul 2021The purpose of this systematic review was to analyze the influence of occlusal reduction on the postoperative pain levels after endodontic treatment (instrumentation and... (Meta-Analysis)
Meta-Analysis
The purpose of this systematic review was to analyze the influence of occlusal reduction on the postoperative pain levels after endodontic treatment (instrumentation and obturation of the root canal system). This review followed the PRISMA statement and was registered at PROSPERO (CRD42018107918). Two independent reviewers searched the Lilacs, Cochrane Library, PubMed (Medline), Web of Science, Scopus, Scielo, and ScienceDirect for articles published until April 2021. The research question was, "Does occlusal reduction decrease postoperative pain in endodontically treated teeth?". Only randomized clinical trials were included. The RevMan 5 program was used for meta-analysis, calculating the relative risk (RR) and 95% confidence interval (CI) of the dichotomous outcome (presence or absence of pain). The search strategies retrieved 4114 studies. Twelve studies were included for qualitative analysis and nine for quantitative analysis. The meta-analysis results did not reveal a significant difference in the reduction of postoperative pain levels for endodontic instrumentation at 6, 12, 24, 48 h and for endodontic obturation at 6 or 12 h after occlusal reduction. According to the GRADE tool, the analyzed outcome was classified as having a moderate level of certainty. It is concluded that occlusal reduction does not interfere with postoperative pain levels after endodontic treatment.
Topics: Humans; Occlusal Adjustment; Pain Management; Pain, Postoperative; Root Canal Obturation; Treatment Outcome
PubMed: 34234168
DOI: 10.1038/s41598-021-93119-6 -
Heliyon Jan 2024The effect of using the custom disk method (CDM) for fabricating digital dentures on patients' masticatory function should be studied to support its use in clinical...
STATEMENT OF PROBLEM
The effect of using the custom disk method (CDM) for fabricating digital dentures on patients' masticatory function should be studied to support its use in clinical practice.
PURPOSE
To investigate the effect of digital dentures fabricated using CDM on patients' masticatory function.
MATERIAL AND METHODS
This single-center prospective clinical study included 20 patients with edentulous maxillary and mandibular arches who used a complete denture. The digital impression and complete denture manufacturing procedures using CDM have already been reported by Kanazawa et al. (2018) [32] and Soeda et al. (2022) [18] Thedigital dentures fabricated with CDM were delivered to the participants, and periodic adjustments were made until the patient could use the denture without pain. A color-changeable chewing gum, two types of gummy jellies that can evaluate the masticatory function, and pressure-sensitive sheets were used to evaluate the participants' masticatory function at baseline, 1 month, and 6 months following adjustment of the new digital complete dentures fabricated with CDM. These masticatory function values had already been measured in the previous conventional dentures and were recorded as baseline values.
RESULTS
The study participants included 8 women and 12 men (mean age, 77.6 years). The color-changeable chewing gum analysis indicated that there was no significant improvement of masticatory function from baseline to 1 M (P = .083) and 6 M (P = .157).The gummy jelly analysis indicated no significant differences between the masticatory function baseline and 1 month (P = .387); however, a significant improvement was observed from baseline to 6 months (P = .020). Tests with Glucolum indicated a significant improvement from baseline to 1 month (P = .012) and 6 months (P = .003). The maximum bite force and occlusal contact area showed no significant difference at any time point.
CONCLUSIONS
Significant improvement in masticatory function was observed upon evaluation with gummy jelly and Glucolum 6 months after delivering the new digital complete dentures. Under limited conditions, the digital denture fabricated using CDM resulted in good recovery of the masticatory function in elderly edentulous patients. The present results combined with the cost-effectiveness and patient satisfaction associated with CDM indicate its clinical utility.
PubMed: 38192789
DOI: 10.1016/j.heliyon.2023.e23938