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The Bulletin of Tokyo Dental College Jun 2021This report describes a case of generalized chronic periodontitis requiring periodontal regenerative therapy. The patient was a 62-year-old man who presented with the...
Periodontal Regenerative Therapy with Recombinant Human Fibroblast Growth Factor-2 and Deproteinized Bovine Bone Mineral in Patient with Chronic Periodontitis: An 18-month Follow-up Report.
This report describes a case of generalized chronic periodontitis requiring periodontal regenerative therapy. The patient was a 62-year-old man who presented with the chief complaint of gingival swelling in the molar region. An initial examination revealed that 31.6% of sites had a probing depth of ≥4 mm and 18.5% bleeding on probing. Radiographic examination revealed vertical bone resorption in #14, 25, 26, 27, 32, 37, 45, and 47, and horizontal resorption in other regions. Based on a clinical diagnosis of moderate chronic periodontitis, initial periodontal therapy consisting of plaque control and scaling and root planing was performed. Occlusal adjustment of premature contact sites was performed after inflammation was suppressed. Surgical periodontal therapy was subsequently performed at selected sites. Periodontal regenerative therapy using recombinant human fibroblast growth factor (rhFGF)-2 was performed on #14, 25, 26, 32, and 37. Combination therapy with rhFGF-2 and deproteinized bovine bone mineral (DBBM) was performed on #45 and 47. Other sites with residual periodontal pockets were treated by open flap debridement, and #27 was extracted due to a bone defect exceeding the root apex. Progress was then reevaluated and the patient placed on supportive periodontal therapy. Periodontal regenerative therapy using rhFGF-2 in combination with DBBM resulted in an improvement in clinical parameters and vertical bone resorption. This improvement has been adequately maintained over an 18-month period. The periodontal treatment provided resulted in a marked improvement in the patient's oral health-related quality of life.
Topics: Alveolar Bone Loss; Animals; Cattle; Chronic Periodontitis; Fibroblast Growth Factor 2; Follow-Up Studies; Guided Tissue Regeneration, Periodontal; Humans; Male; Middle Aged; Minerals; Periodontal Attachment Loss; Quality of Life; Treatment Outcome
PubMed: 33994421
DOI: 10.2209/tdcpublication.2020-0034 -
The Bulletin of Tokyo Dental College Dec 2020Here, we report a case of generalized chronic periodontitis with furcation involvement that was treated successfully by means of surgical intervention. The patient was a...
Here, we report a case of generalized chronic periodontitis with furcation involvement that was treated successfully by means of surgical intervention. The patient was a 43-year-old man requesting treatment for periodontal disease. An initial examination revealed 42% of sites with a probing depth of ≥4 mm and 42.9% of sites with bleeding on probing. The maxillary molars showed varying degrees of furcation involvement. Radiographic examination revealed bone resorption in the molar and mandibular anterior teeth regions. Microbiological examination of subgingival plaque revealed the presence of Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, and Tannerella forsythia. The patient's oral health-related quality of life (OHRQL) was also assessed. Based on a clinical diagnosis of severe chronic periodontitis, initial periodontal therapy was performed. Plaque control, scaling and root planing, extraction, temporary fixed restoration, occlusal adjustment, and root canal treatment were implemented. Following reevaluation, open flap debridement was performed at selected sites. Root resection was performed on the distal root of #16. Prosthetic treatment was then initiated for recovery of oral function. After confirmation of appropriate occlusion and cleanability, the patient was placed on supportive periodontal therapy. Root resection improved cleanability. This clinical improvement has been adequately maintained over a 2-year period. The patient's OHRQL score showed a slight deterioration during the supportive periodontal therapy OK period, however. This indicates the need for further careful monitoring of periodontal conditions, as well as of how they are perceived by the patient themselves.
Topics: Adult; Aggressive Periodontitis; Alveolar Bone Loss; Dental Scaling; Follow-Up Studies; Humans; Male; Periodontal Attachment Loss; Periodontal Pocket; Quality of Life; Root Planing
PubMed: 33177273
DOI: 10.2209/tdcpublication.2020-0020 -
The Bulletin of Tokyo Dental College Jun 2022This report describes a case of generalized chronic periodontitis requiring periodontal therapy including periodontal regeneration. The patient was a 59-year-old man who...
Treatment of Chronic Periodontitis with Periodontal Surgery Including Regenerative Therapy Using Recombinant Human Fibroblast Growth Factor-2 and Papilla Preservation Technique: A Case Report with a Two-year Follow-up.
This report describes a case of generalized chronic periodontitis requiring periodontal therapy including periodontal regeneration. The patient was a 59-year-old man who visited the Tokyo Dental College Suidobashi Hospital with the chief complaint of mobility in tooth #47. Periodontal examination at the first visit revealed that 32.1% of sites had a probing depth of ≥4 mm and 32.7% of sites bleeding on probing. Radiographic examination revealed vertical bone resorption in #26 and horizontal resorption in #12, 13, 42, and 43. Based on a clinical diagnosis of severe chronic periodontitis, initial periodontal therapy consisting of plaque control, scaling and root planing, occlusal adjustment, caries treatment, and placement of an occlusal splint was performed. Tooth #47 was extracted due to bone resorption extending as far as the root apex. After reevaluation, surgical periodontal treatment was performed at the selected site. Periodontal regenerative therapy using recombinant human fibroblast growth factor (rhFGF)-2 and papilla preservation technique was performed for #26. To reduce periodontal pockets, open flap debridement was implemented for #12, 13, 42, and 43. After reevaluation, the patient was placed on supportive periodontal therapy (SPT). Periodontal regenerative therapy with rhFGF-2 and modified papilla preservation technique yielded an improvement in angular bone resorption which has been properly maintained for two years. Periodontal therapy with open flap debridement resulted in an improvement in horizontal bone resorption. Continued SPT is needed to maintain a stable periodontal condition.
Topics: Alveolar Bone Loss; Chronic Periodontitis; Dental Enamel Proteins; Dental Scaling; Fibroblast Growth Factor 2; Follow-Up Studies; Humans; Male; Middle Aged; Periodontal Attachment Loss; Treatment Outcome
PubMed: 35613866
DOI: 10.2209/tdcpublication.2021-0048 -
Trauma Case Reports Aug 2019In general, internal plate fixation is mainly performed in order to reduce multiple facial bone fractures and rarely uses an external fixator. Although it would be ideal...
In general, internal plate fixation is mainly performed in order to reduce multiple facial bone fractures and rarely uses an external fixator. Although it would be ideal to successfully achieve or preserve the occlusal relationship of the upper and lower jaws, it is difficult to successfully manage multiple bone fragments in order to use them to achieve internal fixation, especially when treating a severely comminuted facial fracture. In addition, it is also important to prevent the onset of severe infection after sub-periosteal dissection, due to the presence of avascular bony fragments and an internal fixation implant which thus represents a foreign body. In order to treat extensive comminuted fracture without internal plate fixation, we performed external fixation using an Ilizarov-type external fixator. The Ilizarov-type external fixator is characterized by a few circular external structures and threaded rods. This device can be modified for use in the field of orthopedic surgery to correct three-dimensional deformities caused by fragile complicated fractures and bone defects. The advantages of the Ilizarov-type external fixator for treating panfacial fractures include a low invasiveness, utility in various fracture situations, easy adjustment of threaded rods, and a low potential cost. We herein report the first case of a severe panfacial fracture that was successfully treated using an Ilizarov-type external fixator.
PubMed: 31294071
DOI: 10.1016/j.tcr.2019.100214 -
The Bulletin of Tokyo Dental College Dec 2023This report describes a case of Stage III Grade C periodontitis requiring periodontal regenerative therapy. The patient was a 19-year-old woman who presented with the...
A Case Report of Periodontal Regenerative Therapy Using Recombinant Human Fibroblast Growth Factor 2 and Deproteinized Bovine Bone Mineral with Non-incised Papillae Surgical Approach (NIPSA) for Angular Bone Defect in Patient with Stage III Grade C Periodontitis.
This report describes a case of Stage III Grade C periodontitis requiring periodontal regenerative therapy. The patient was a 19-year-old woman who presented with the chief complaint of gingival recession in the incisor region. An initial examination revealed that 45.3% of sites had a probing depth of ≥4 mm and 45.8% bleeding on probing. Radiographic examination showed angular bone resorption in #25, 26, 31, 36, and 46 and horizontal resorption in other regions. Initial periodontal therapy was implemented based on a clinical diagnosis of Stage III Grade C periodontitis (generalized aggressive periodontitis). Occlusal adjustment was also performed at sites showing premature contact (#26 and 36) after suppression of inflammation. Periodontal regenerative therapy using recombinant human fibroblast growth factor (rhFGF) -2 was performed on #25, 26, and 46. Combination therapy with rhFGF-2 and deproteinized bovine bone mineral (DBBM) was performed on #31 and 36. A non-incised papillae surgical approach (NIPSA) was used on #31. Periodontal conditions were then re-evaluated and the patient placed on supportive periodontal therapy. Regenerative therapy using rhFGF-2 and DBBM with NIPSA yielded an improvement in clinical parameters and bone resorption. This improvement has been adequately maintained over a 12-month period. Continued care is needed to maintain stable periodontal conditions.
Topics: Animals; Cattle; Female; Humans; Young Adult; Aggressive Periodontitis; Alveolar Bone Loss; Fibroblast Growth Factor 2; Follow-Up Studies; Gingival Diseases; Guided Tissue Regeneration, Periodontal; Minerals; Periodontal Attachment Loss; Treatment Outcome
PubMed: 37967939
DOI: 10.2209/tdcpublication.2023-0011 -
Cureus Feb 2024Implant-supported restorations have gained popularity in modern dentistry, and the choice of abutment material is crucial for their long-term success. This in vitro...
BACKGROUND
Implant-supported restorations have gained popularity in modern dentistry, and the choice of abutment material is crucial for their long-term success. This in vitro study aimed to evaluate the fracture resistance and failure mode of implant-supported restorations using different abutment materials.
METHODS
Ninety standardized implant-supported restorations were included in the study. Abutments made of titanium, zirconia, and a hybrid material (titanium base with a zirconia veneer) were evaluated. Standardized abutments were fabricated, and screw-retained restorations were fabricated using a resin-based composite material. Cyclic loading was applied using a universal testing machine to simulate masticatory forces. Fracture resistance was measured in terms of the number of cycles to failure (NCF), and failure modes were analyzed.
RESULTS
The findings indicate that zirconia abutments exhibited higher fracture resistance compared to titanium and hybrid abutments. Longer implants demonstrated higher fracture resistance, suggesting improved stability and resistance to mechanical forces. Increased loading angles resulted in decreased fracture resistance of implant-supported restorations, emphasizing the need for proper occlusal adjustment. Central loading showed higher fracture resistance than lateral and posterior loading locations. The distribution of failure modes varied among the abutment materials, with bulk prosthesis fracture being the most common in the titanium group, while abutment fracture was predominant in the zirconia and hybrid groups.
CONCLUSION
This in vitro study demonstrated that the choice of abutment material significantly influenced the fracture resistance and failure mode of implant-supported restorations. Zirconia abutments exhibited the highest fracture resistance, followed by hybrid and titanium abutments. The failure mode analysis revealed different patterns of failure for each abutment material.
PubMed: 38529462
DOI: 10.7759/cureus.54624 -
Journal of the Mechanical Behavior of... Jun 2024Additive manufacturing enables local grading of the stiffness of dental implants through targeted adjustment of the manufacturing parameters to meet patient specific...
Additive manufacturing enables local grading of the stiffness of dental implants through targeted adjustment of the manufacturing parameters to meet patient specific requirements. The extent to which such a manufacturing approach affects the interaction between the implant body and the surrounding bone, and what grading is optimal, is currently insufficiently investigated. This study investigates the effect of different Young's modulus grading approaches on stresses in the peri-implant bone via finite element analysis. The implant geometry was kept constant and in the case of the implant a node-dependent elastic modulus was assigned. In this way, a vertical, a radial and three torus based grading approaches were created and examined. A load was then applied directly to the occlusal surface of the implant crown. It was found that a local grading utilizing a torus shape was most favourable in terms of an effective stress peak reduction. The best torus shape tested achieved a 22 % reduction of maximum principal stress and 6 % reduction of minimum principal stress compared to the uniform material. In clinical settings, this may provide benefits in situations of overload. Based on the results, a graded stiffness in dental implants appears to be of interest for developing advanced, patient-specific implant solutions.
Topics: Humans; Dental Implants; Finite Element Analysis; Elastic Modulus; Crowns; Stress, Mechanical; Dental Stress Analysis; Computer Simulation
PubMed: 38552334
DOI: 10.1016/j.jmbbm.2024.106530 -
The Bulletin of Tokyo Dental College Jun 2021We report a case of generalized chronic periodontitis requiring periodontal regenerative therapy. The patient was a 53-year-old woman who presented with the chief...
We report a case of generalized chronic periodontitis requiring periodontal regenerative therapy. The patient was a 53-year-old woman who presented with the chief complaint of gingival swelling. An initial examination revealed 31.5% of sites with a probing depth of ≥4 mm and 46.3% with bleeding on probing. Radiographic examination showed vertical bone resorption in tooth #33. Horizontal adsorption was also observed in other areas. Based on a clinical diagnosis of severe generalized chronic periodontitis, initial periodontal therapy consisting of plaque control, scaling and root planing, occlusal adjustment, caries treatment, and splint placement was performed. After re-evaluation, surgical periodontal treatment was performed at selected sites. Periodontal regeneration therapy with recombinant human fibroblast growth factor (rhFGF)-2 was performed at #33. Two other sites (#14, 15), which had residual periodontal pockets, were treated by open-flap debridement. After re-evaluation, the patient was placed on a maintenance program. Periodontal regenerative therapy with rhFGF-2 resulted in an improvement in angular bone resorption, which has been properly maintained for 2 years. Continued care is needed to maintain stable periodontal conditions.
Topics: Alveolar Bone Loss; Chronic Periodontitis; Dental Enamel Proteins; Dental Scaling; Female; Fibroblast Growth Factor 2; Follow-Up Studies; Guided Tissue Regeneration, Periodontal; Humans; Middle Aged; Periodontal Attachment Loss; Treatment Outcome
PubMed: 33994424
DOI: 10.2209/tdcpublication.2020-0045