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JBJS Essential Surgical Techniques 2021The goal of the osteochondral autograft transplantation (OAT) procedure is to replace both the bone and cartilage that have been compromised by osteonecrosis of the...
BACKGROUND
The goal of the osteochondral autograft transplantation (OAT) procedure is to replace both the bone and cartilage that have been compromised by osteonecrosis of the capitellum, a condition known as osteochondritis dissecans (OCD). In children, the vascularity of the capitellum is limited compared with that in adults because the physis acts as a physical barrier to vascular ingrowth from the metaphysis to the epiphysis. The necrotic subchondral bone cannot keep up with the weight-bearing demands of certain high-level athletes such as gymnasts, accumulating microfractures and eventually crumbling. Without the support of the subchondral bone, the overlying cartilage fractures and eventually comes loose, often floating around the joint as a loose body. Fibrocartilage may form to fill the void left behind but cannot restore either the structural integrity of the bone or the gliding and compressive properties of hyaline cartilage. Replacement of both the bone and the cartilage requires an osteochondral transplant. Fortunately, there are regions of the articular surface of the knee in which there is minimal load or contact and that are therefore expendable as donor osteochondral plugs. We prefer a single-plug technique whenever possible because it is easier to perform and only requires union of the plug to native bone across 1 interface. If a single plug will not cover the defect or cannot be made to match the contour of the capitellum, multiple plugs may be used (i.e., mosaicplasty).
DESCRIPTION
Place the patient with the operative side up in the lateral decubitus position with the arm in a holder. First, perform a diagnostic elbow arthroscopy. Use the proximal anteromedial portal to insert the scope across the front of the joint. Using a switching stick, make an anterolateral portal. Place a cannula to prevent having to go in and out of the joint multiple times, as this increases the risk of neurologic injury. Perform a synovectomy if necessary and remove any loose bodies. The absence of synovitis is a sign that the lesion has likely healed. Inspect the capitellum and radial head. The anterior margin of the OCD lesion of the capitellum will be barely visible as the joint is brought to extension.If the lesion is readily visible in the anterior compartment, the lesion will be too anterior to approach from an anconeus split approach. In this case, some have advocated a takedown of the lateral collateral ligament to aid in visualization from a lateral approach. We have had good success with a direct anterior approach between the brachialis and brachioradialis, mobilizing the radial nerve laterally.If the chondral injury is extensive or includes the articular surface of the radial head, then the injury is too advanced to successfully treat with an OAT procedure. In these cases, we perform an interposition arthroplasty of the radiocapitellar joint. Radial head resection is not an option in a child because of the high risk of proximal radial migration. Radial head replacement likewise is not an option because of the high risk of failure.Switch the viewing and working portals again with use of switching sticks and repeat the process for the medial side of the joint. Make a direct posterior and a proximal posterolateral portal. Never debride on or near the medial gutter because the ulnar nerve is immediately adjacent. Establish a soft spot portal and place the scope through it. Loose bodies and extensive synovitis are typically seen in this area when the soft spot portal is used as a viewing portal. The OCD lesion should be visible through the soft spot portal. If the lesion is not readily visible with some elbow flexion, then the lesion is probably too anterior for an anconeus split approach and an anterior approach should be considered.Challenge the lesion with a probe. If the cartilage is damaged but the subchondral bone holds firm, perform a microfracture technique. If the cartilage is soft or unstable and the underlying bone is compromised, perform an OAT procedure. In the majority of cases in which the lesion is accessible posteriorly, connect the proximal posterolateral portal and the soft spot portal and split the anconeus. The lesion will be visible in deep flexion. There are several options for instrumentation from multiple manufacturers that each have their own advantages and disadvantages. Using a recipient harvester, remove the diseased bone and cartilage to a stable rim, keeping the harvester as perpendicular to the surface as possible.At the knee, make a 3-cm transverse incision directly over the superolateral corner of the lateral femoral condyle. Harvest an appropriately sized plug from the superolateral corner of the articular surface. Inspect the plug because it will often be slightly thicker on one side. Rotate the plug to match the contour of the defect in the capitellum. Mallet the donor plug into the recipient deficit with gentle taps, using as few taps as possible to limit chondrocyte injury. Fill the defect in the knee with your choice of bone substitute. Close both wounds in layers.
ALTERNATIVES
Other options include allograft plugs, periosteal resurfacing, bone grafting, retrograde and antegrade drilling, and observation.
RATIONALE
The OCD lesion involves both bone and cartilage. There is now ample evidence that replacing both as a unit yields the best outcomes.
EXPECTED OUTCOMES
Approximately 90% of patients will return to sports participation, and 80% of patients can expect to return to sport at their previous level of participation.
IMPORTANT TIPS
A diagnostic arthroscopy confirms the need for the OAT procedure and identifies other pathologies.Remove all of the diseased bone with the recipient harvester.Match the size and contour of the lesion as closely as possible with the plug.Immobilize the elbow in a cast for 4 weeks.
PubMed: 34277134
DOI: 10.2106/JBJS.ST.20.00032 -
JSES International Jan 2021It is generally considered that fragment fixation with bone pegs (FFBP) for osteochondritis dissecans (OCD) of the humeral capitellum can be indicated for stages I and...
BACKGROUND AND HYPOTHESIS
It is generally considered that fragment fixation with bone pegs (FFBP) for osteochondritis dissecans (OCD) of the humeral capitellum can be indicated for stages I and II according to the International Cartilage Repair Society (ICRS) classification of OCD and it is difficult to obtain complete bone union for advanced lesions. However, the clinical and radiologic results of FFBP with cancellous bone graft for ICRS-OCD stage III with lateral wall involvement have not been described in detail. Good bone union can be achieved with the lateral wall fragment of the capitellum by FFBP in combination with refreshing the sclerotic surface at the base of the lesion and cancellous bone grafting even in ICRS-OCD stage III lesions.
METHODS
In total, 10 adolescent baseball players with a diagnosis of OCD, a median age of 13.5 years at the time of surgery, and 26.7 months of postoperative follow-up were included. Preoperative imaging showed that all patients had lesions in the late detached stage and of the lateral-widespread type based on the site of the focal lesion. The intraoperative ICRS-OCD classification was stage III. We aimed to preserve and fix the lateral wall fragment with cancellous bone grafting if the condition of the articular cartilage was good and the size and thickness of the segment could withstand fixation.
RESULTS
Bone union of the lateral wall fragment was achieved in all cases. The elbow extension range of motion was -3.9° ± 9.7° before surgery and was eventually -0.4° ± 6.7° at the final assessment. Flexion range of motion ranged from 138.1° ± 10.5° to 142.4° ± 6.2°. The Timmerman and Andrews score significantly improved from 165.5 ± 10.9 points before surgery to 197.0 ± 6.3 points after surgery, demonstrating excellent results in all patients. All patients were able to return to competitive baseball.
CONCLUSION
The radiographic and clinical outcomes of FFBP for lateral wall fragments with cancellous bone graft were satisfactory, showing that the indications for this procedure could be extended to ICRS-OCD stage III.
PubMed: 33554161
DOI: 10.1016/j.jseint.2020.09.002 -
Revista Espanola de Cirugia Ortopedica... 2021Juvenile osteochondritis dissecans (JOCD) is an acquired joint disease of unknown etiology that affects skeletally immature patients and has the potential to progress to...
BACKGROUND
Juvenile osteochondritis dissecans (JOCD) is an acquired joint disease of unknown etiology that affects skeletally immature patients and has the potential to progress to osteoarthritis. Recent studies have reported a high prevalence of vitaminD deficiency in patients with osteochondral lesions. The aim of our study was to determine serum vitaminD levels in patients diagnosed with JOCD.
METHODS
Serum 25(OH)D levels of 31 patients (22 males) presenting 40 lesions (29 JOCD of the knee, and 11 of the ankle) were evaluated. The average age was 11.9±2.9years. HypovitaminosisD was defined as a value less than 30ng/mL and was divided into vitaminD insufficiency (20 to 30ng/mL) and vitaminD deficiency (<20ng/mL).
RESULTS
HypovitaminosisD was present in 45.2% of the evaluated patients (32.2% insufficiency and 13% deficiency). No significant differences were found in the mean values and incidence of hypovitaminosis between those patients in which the sample was taken in warm or cold season (P=.267 and P=.875, respectively). Patients who required surgery had a higher incidence of hypovitaminosis than those treated conservatively (60% versus 31%, P=.054). There was no correlation in the incidence of hypovitaminosis with sex, location, stability of the lesion, or if the lesion was uni- or bilateral.
CONCLUSION
In our series, almost half of the patients diagnosed with JOCD presented abnormal serum levels of vitaminD. A two-fold incidence of hypovitaminosis was observed in patients requiring surgical treatment compared to patients managed conservatively. The association found in this study does not imply causation, but it should be considered within the set of actions for the treatment of these injuries.
PubMed: 33281101
DOI: 10.1016/j.recot.2020.07.006 -
JSES International Nov 2023Introducing and implementing an arthroscopic classification tool for posterolateral elbow instability.
BACKGROUND
Introducing and implementing an arthroscopic classification tool for posterolateral elbow instability.
METHODS
Thirty arthroscopies were performed on 30 patients, and all recordings were collected, blinded, and labeled. Three orthopedic surgeons reviewed and scored all 30 recordings three times with a period of at least seven days in between to analyze the intraobserver and interobserver reliability. The classification consisted of five different grades.
RESULTS
Indications for elbow arthroscopy included impingement (n = 7), osteochondritis dissecans (n = 5), pain (n = 7), osteoarthritis (n = 6), and other (n = 5). The kappa value for intrarater reliability was 0.71, indicating good reliability, while the kappa value for inter-rater reliability was 0.38 indicating fair reliability.
CONCLUSION
This new classification is a tool for an arthroscopic assessment of PLRI and can be used as a standardized grading system for further research and communication between orthopedic surgeons. We demonstrated good intrarater reliability (k = 0.71) with fair inter-rater reliability (k = 0.38). However, further research is necessary to study the clinical significance.
PubMed: 37969525
DOI: 10.1016/j.jseint.2023.02.016 -
JSES International Mar 2024Osteochondritis dissecans (OCD) of the capitellum is a well-described condition that most commonly affects adolescent throwing athletes and gymnasts. There is no gold... (Review)
Review
BACKGROUND
Osteochondritis dissecans (OCD) of the capitellum is a well-described condition that most commonly affects adolescent throwing athletes and gymnasts. There is no gold standard rehabilitation protocol or timing for return to sport (RTS) after surgical management of OCD of the capitellum.
HYPOTHESIS/PURPOSE
The purpose of the study was to identify in the existing literature any criteria used for RTS following surgical treatment of OCD of the capitellum. The hypothesis was that surgeons would utilize length of time rather than functional criteria or performance benchmarks for RTS.
METHODS
Level 1 to 4 studies evaluating athletes who underwent surgery for OCD of the capitellum with a minimum follow-up of 1-year were included. Studies not describing RTS criteria, including less than 1-year follow-up, non-operative management only, and revision procedures were excluded. Each study was analyzed for RTS criteria, RTS rate, RTS timeline, sport played, level of competition, graft source (if utilized), and postoperative rehabilitation parameters. Assessment of bias and methodological quality was performed using the Coleman methodology score and RTS value assessment.
RESULTS
All studies reported a rehabilitation protocol with immobilization followed by bracing with progressive range of motion. RTS rate was 80.9% (233/288). The majority of studies reported using time-based criteria for RTS (11/15). The most commonly reported timeline was 6 months (range: 3-12 months).
CONCLUSION
The overall RTS rate after surgical treatment of capitellar OCD is high with no consensus on RTS criteria. The two most consistent RTS criteria reported in the literature are return of elbow range of motion and healing demonstrated on postoperative imaging. There is a wide range of time to RTS in the literature, which may be sport dependent. Further research is needed to develop functional and performance-based metrics to better standardize RTS criteria and rehabilitation protocols.
PubMed: 38464452
DOI: 10.1016/j.jseint.2023.11.003 -
Orthopadie (Heidelberg, Germany) Jan 2024Chondral and osteochondral lesions encompass several acute or chronic defects of the articular cartilage and/or subchondral bone. These lesions can result from several... (Review)
Review
Chondral and osteochondral lesions encompass several acute or chronic defects of the articular cartilage and/or subchondral bone. These lesions can result from several different diseases and injuries, including osteochondritis dissecans, osteochondral defects, osteochondral fractures, subchondral bone osteonecrosis, and insufficiency fractures. As the cartilage has a low capacity for regeneration and self-repair, these lesions can progress to osteoarthritis. This study provides a comprehensive overview of the subject matter that it covers. PubMed, Scopus and Google Scholar were accessed using the following keywords: "chondral lesions/defects of the femoral head", "chondral/cartilage lesions/defects of the acetabulum", "chondral/cartilage lesions/defects of the hip", "osteochondral lesions of the femoral head", "osteochondral lesions of the acetabulum", "osteochondral lesions of the hip", "osteochondritis dissecans," "early osteoarthritis of the hip," and "early stage avascular necrosis". Hip osteochondral injuries can cause significant damage to the articular surface and diminish the quality of life. It can be difficult to treat such injuries, especially in patients who are young and active. Several methods are used to treat chondral and osteochondral injuries of the hip, such as mesenchymal stem cells and cell-based treatment, surgical repair, and microfractures. Realignment of bony anatomy may also be necessary for optimal outcomes. Despite several treatments being successful, there is a lack of head-to-head comparisons and large sample size studies in the current literature. Additional research will be required to provide appropriate clinical recommendations for treating chondral/osteochondral injuries of the hip joint.
Topics: Humans; Osteochondritis Dissecans; Quality of Life; Cartilage, Articular; Cartilage Diseases; Acetabulum; Osteonecrosis; Osteoarthritis
PubMed: 37815635
DOI: 10.1007/s00132-023-04444-9 -
Arthroscopy, Sports Medicine, and... Dec 2022To determine the functional outcomes of adolescent athletes treated with arthroscopic marrow stimulation/microfracture for elbow capitellar osteochondritis dissecans...
PURPOSE
To determine the functional outcomes of adolescent athletes treated with arthroscopic marrow stimulation/microfracture for elbow capitellar osteochondritis dissecans (OCD).
METHODS
The medical records for all patients younger than 18 years of age with capitellar OCD who underwent arthroscopic treatment at a single institution were retrospectively reviewed. The variables examined included patient characteristics, bone age, pre- and postoperative lesion grade/size and range of motion (ROM), intraoperative lesion grade/size, time to postoperative return to sport, and validated outcome scores.
RESULTS
Twenty patients with 21 treated elbows met the study's inclusion criteria. Three patients were not available for follow-up, leaving 18 of 21 (85.7%) elbows in the final cohort. Mean age and follow-up was 14.1 and 4.4 years, respectively. All 18 elbows were treated with diagnostic arthroscopy, arthroscopic debridement with loose body removal as indicated, and marrow stimulation. Sixteen of 18 (88.9%) elbows returned to sports postoperatively, with 12 of 18 (66.7%) elbows returning to their primary sport at the same level or higher. Overall, there were significant improvements in elbow ROM (132.8°, range 120°-140° postoperatively, compared with 122.1°, range 80°-140° preoperatively) ( = .002) and excellent Quick Disabilities of the Arm, Shoulder and Hand scores (mean 2.3 ± 5.1), as well as Kerlan-Jobe Orthopaedic Clinic Overhead Athlete Shoulder and Elbow scores (mean 94.1 ± 8.7) in those who returned to sports. There was no correlation with outcome or return to sport for preoperative lesion grade/size, bone age, physeal status or open versus arthroscopic treatment.
CONCLUSIONS
Arthroscopic debridement and marrow stimulation for capitellar OCD in adolescent athletes leads to improvements in ROM, as well as a high rate of return to sport, and high levels of athletic and daily functional activity during follow-up, regardless of bone age and lesion grade/size at time of surgery.
LEVEL OF EVIDENCE
Level IV, therapeutic case series.
PubMed: 36579032
DOI: 10.1016/j.asmr.2022.08.007 -
Cartilage Dec 2023Loose bodies are free-floating tissues of cartilage and bone that can cause pain, swelling, the inability to straighten the knee, or intermittent locking of the knee....
OBJECTIVE
Loose bodies are free-floating tissues of cartilage and bone that can cause pain, swelling, the inability to straighten the knee, or intermittent locking of the knee. Loose bodies can arise from degenerative joint disease, flake fractures, osteochondritis dissecans, or chondromatosis. We hypothesized that loose bodies can be classified in stages with tissue characteristics similar to endochondral ossification.
DESIGN
Loose bodies were harvested from patients undergoing joint replacement. Samples were processed for histology, gene expression analysis, and micro-computed tomography (µCT). Cartilage- and bone-related genes and proteins were selected for immunofluorescence stainings (collagen type I, II, and X, SOX9 [SRY-box transcription factor 9], and MMP13 [matrix metalloproteinase 13]) and gene expression analysis ( [fibronectin], , and aggrecan []).
RESULTS
Loose bodies were grouped in 4 stages: fibrous, (mineralized) cartilaginous, cartilage and bone, and bone. Hyaline-like cartilage tissue with Benninghoff arcades was present in stages 2 and 3. A transition from cartilaginous to mineralized tissue and bone trabecula was defined by an increase in and (stage 3 vs. 4: = 0.047) positive area. Stage 4 showed typical trabecular bone tissue. The relative volume of calcified tissue (mineralized cartilage and bone tissue) decreased with stages (stages 1-2 vs. 3: = 0.002; stage 1-2 vs. 4: = 0.012). expression and stained area decreased from stages 1-2 to 4 ( = 0.010 and = 0.004). expression decreased from stage 1-2 to stage 3 ( = 0.049) and stage 4 ( = 0.002).
CONCLUSION
Loose bodies show tissue characteristics similar to endochondral ossification. They are probably a relevant substrate for regenerative therapeutic interventions in joint disease.
PubMed: 38041252
DOI: 10.1177/19476035231212608 -
Shoulder & Elbow Aug 2020(1) To determine the interobserver reliability of magnetic resonance classifications and lesion instability criteria for capitellar osteochondritis dissecans lesions and...
AIM
(1) To determine the interobserver reliability of magnetic resonance classifications and lesion instability criteria for capitellar osteochondritis dissecans lesions and (2) to assess differences in reliability between subgroups.
METHODS
Magnetic resonance images of 20 patients with capitellar osteochondritis dissecans were reviewed by 33 observers, 18 orthopaedic surgeons and 15 musculoskeletal radiologists. Observers were asked to classify the osteochondritis dissecans according to classifications developed by Hepple, Dipaola/Nelson, Itsubo, as well as to apply the lesion instability criteria of DeSmet/Kijowski and Satake. Interobserver agreement was calculated using the multirater kappa (k) coefficient.
RESULTS
Interobserver agreement ranged from slight to fair: Hepple (k = 0.23); Dipaola/Nelson (k = 0.19); Itsubo (k = 0.18); DeSmet/Kijowksi (k = 0.16); Satake (k = 0.12). When classifications/instability criteria were dichotomized into either a stable or unstable osteochondritis dissecans, there was more agreement for Hepple (k = 0.52; p = .002), Dipaola/Nelson (k = 0.38; p = .015), DeSmet/Kijowski (k = 0.42; p = .001) and Satake (k = 0.41; p < .001). Overall, agreement was not associated with the number of years in practice or the number of osteochondritis dissecans cases encountered per year (p > .05).
CONCLUSION
One should be cautious when assigning grades using magnetic resonance classifications for capitellar osteochondritis dissecans. When making treatment decisions, one should rather use relatively simple distinctions (e.g. stable versus unstable osteochondritis dissecans; lateral wall intact versus not intact), as these are more reliable.
PubMed: 32782483
DOI: 10.1177/1758573218821151 -
JSES International May 2021This study aimed to investigate the results, indications, and limitations of absorbable pin fixation for osteochondritis dissecans of the humeral capitellum in the...
HYPOTHESIS
This study aimed to investigate the results, indications, and limitations of absorbable pin fixation for osteochondritis dissecans of the humeral capitellum in the separation stage.
METHODS
This study included 35 patients (mean age, 14.0 years). Patients were divided into two groups: Group A included those who obtained complete union within 6 months and Group B included those who did not observe complete union within 6 months. The clinical findings were compared between the groups.
RESULTS
There were 26 and 6 patients in Groups A and B, respectively. Two patients did not obtain complete union. Clinical outcomes improved after the procedure. In univariate analysis, delayed union was associated with larger major diameter ( = .0004) and more depth ( = .03) of the osteochondral fragment measured by computed tomography, the presence of osteosclerosis in the subchondral bed on X-ray imaging ( = .003), and the presence of comminution of subchondral bone on ultrasound imaging ( = .01). In multivariate analysis, there was a significant difference only in the major diameter of the osteochondral fragment ( = .03). Receiver operating characteristic curves analysis shows that if the major diameter of the osteochondral fragment is 11 mm or less, 85% of patients achieve complete union of the osteochondral fragments within 6 months.
CONCLUSION
Absorbable pin fixation may be considered for the osteochondral fragments with major diameter of 11 mm or less and should not be considered for patients who demonstrate osteosclerosis in the subchondral bed or comminution of subchondral bone.
PubMed: 34136872
DOI: 10.1016/j.jseint.2020.12.017