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Journal of the American Medical... Jan 2023To report the overall prevalence of social frailty among older people and provide information for policymakers and authorities to use in developing policies and social... (Meta-Analysis)
Meta-Analysis Review
OBJECTIVE
To report the overall prevalence of social frailty among older people and provide information for policymakers and authorities to use in developing policies and social care.
DESIGN
A systematic review and meta-analysis.
SETTING AND PARTICIPANTS
We searched 4 databases (PubMed, Embase, Web of Science, and Google Scholar) to find articles from inception to July 30, 2022. We included cross-sectional and cohort studies that provided the prevalence of social frailty among adults aged 60 years or older, in any setting.
METHODS
Three researchers independently reviewed the literature and retrieved the data. A risk of bias tool was used to assess each study's quality. A random-effect meta-analysis was performed to pool the data, followed by subgroup analysis, sensitivity analysis, and meta-regression.
RESULTS
From 761 records, we extracted 43 studies with 83,907 participants for meta-analysis. The pooled prevalence of social frailty in hospital settings was 47.3% (95% CI: 32.2%-62.4%); among studies in community settings, the pooled prevalence was 18.8% (95% CI: 14.9%-22.7%; P < .001). The prevalence of social frailty was higher when assessed using the Tilburg Frailty Indicator (32.3%; 95% CI: 23.1%-41.5%) than the Makizako Social Frailty Index (27.7%; 95% CI: 21.6%-33.8%) or Social Frailty Screening Index (13.4%; 95% CI: 8.4%-18.4%). Based on limited community studies in individual countries using various instruments, social frailty was lowest in China (4.9%; 95% CI: 4.2%-5.7%), followed by Spain (11.6%; 95% CI: 9.9%-13.3%), Japan (16.2%; 95% CI: 12.2%-20.3%), Korea (26.6%; 95% CI: 7.1%-46.1%), European urban centers (29.2%; 95% CI: 27.9%-30.5%), and the Netherlands (27.2%; 95% CI: 16.9%-37.5%). No other subgroup analyses showed any statistically significant prevalence difference between groups.
CONCLUSION AND IMPLICATIONS
The prevalence of social frailty among older adults is high. Settings, country, and method for assessing social frailty affected the prevalence. More valid comparisons will await consensus on measurement tools and more research on geographically representative populations. Nevertheless, these results suggest that public health professionals and policymakers should seriously consider social frailty in research and program planning involving older adults.
Topics: Humans; Aged; Frailty; Prevalence; Cross-Sectional Studies; Social Group; Hospitals; Frail Elderly
PubMed: 36402197
DOI: 10.1016/j.jamda.2022.10.007 -
Cell Mar 2020Social impairment is frequently associated with mitochondrial dysfunction and altered neurotransmission. Although mitochondrial function is crucial for brain...
Social impairment is frequently associated with mitochondrial dysfunction and altered neurotransmission. Although mitochondrial function is crucial for brain homeostasis, it remains unknown whether mitochondrial disruption contributes to social behavioral deficits. Here, we show that Drosophila mutants in the homolog of the human CYFIP1, a gene linked to autism and schizophrenia, exhibit mitochondrial hyperactivity and altered group behavior. We identify the regulation of GABA availability by mitochondrial activity as a biologically relevant mechanism and demonstrate its contribution to social behavior. Specifically, increased mitochondrial activity causes gamma aminobutyric acid (GABA) sequestration in the mitochondria, reducing GABAergic signaling and resulting in social deficits. Pharmacological and genetic manipulation of mitochondrial activity or GABA signaling corrects the observed abnormalities. We identify Aralar as the mitochondrial transporter that sequesters GABA upon increased mitochondrial activity. This study increases our understanding of how mitochondria modulate neuronal homeostasis and social behavior under physiopathological conditions.
Topics: Adaptor Proteins, Signal Transducing; Animals; Animals, Genetically Modified; Aspartic Acid; Calcium; Calcium-Binding Proteins; Drosophila Proteins; Drosophila melanogaster; Glucose; Homeostasis; Humans; Male; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Proteins; Neurons; Social Behavior; Synaptic Transmission; gamma-Aminobutyric Acid
PubMed: 32200800
DOI: 10.1016/j.cell.2020.02.044 -
Nature Nov 2021Social memory-the ability to recognize and remember familiar conspecifics-is critical for the survival of an animal in its social group. The dorsal CA2 (dCA2) and...
Social memory-the ability to recognize and remember familiar conspecifics-is critical for the survival of an animal in its social group. The dorsal CA2 (dCA2) and ventral CA1 (vCA1) subregions of the hippocampus, and their projection targets, have important roles in social memory. However, the relevant extrahippocampal input regions remain poorly defined. Here we identify the medial septum (MS) as a dCA2 input region that is critical for social memory and reveal that modulation of the MS by serotonin (5-HT) bidirectionally controls social memory formation, thereby affecting memory stability. Novel social interactions increase activity in dCA2-projecting MS neurons and induce plasticity at glutamatergic synapses from MS neurons onto dCA2 pyramidal neurons. The activity of dCA2-projecting MS cells is enhanced by the neuromodulator 5-HT acting on 5-HT receptors. Moreover, optogenetic manipulation of median raphe 5-HT terminals in the MS bidirectionally regulates social memory stability. This work expands our understanding of the neural mechanisms by which social interactions lead to social memory and provides evidence that 5-HT has a critical role in promoting not only prosocial behaviours, but also social memory, by influencing distinct target structures.
Topics: Animals; CA2 Region, Hippocampal; Female; Glutamic Acid; Male; Memory; Mice; Neural Pathways; Neuronal Plasticity; Optogenetics; Pyramidal Cells; Receptor, Serotonin, 5-HT1B; Septal Nuclei; Serotonin; Social Behavior; Synapses
PubMed: 34616037
DOI: 10.1038/s41586-021-03956-8 -
Frontiers in Psychology 2023Studies on radicalization tend to focus on the dynamics of extremist groups and how they exploit grievances of vulnerable individuals. It is imperative, however, to also...
Studies on radicalization tend to focus on the dynamics of extremist groups and how they exploit grievances of vulnerable individuals. It is imperative, however, to also understand the societal factors that lead to such vulnerabilities and grievances. Our social environment plays a key role in how we view the world and shape our beliefs. By understanding the social dynamics, we can gain insight into the motivations that drive people to extremism. Throughout this paper, we examine the societal factors and processes such as discriminative institutional structures and social norms/practices that can make an individual vulnerable and serve as a driving force for them to join a radical group. To do that, we use the process-oriented psychology of Arnold Mindell and the phenomenology of whiteness of Sara Ahmed as our theoretical framework. These frameworks help us map out the societal dynamics causing individuals to carve social niches out of their current social group and into an extremist group. We use interviews with ex-militants of the radical group, Islamic State of Iraq and Syria, to show how certain societal dynamics, such as social injustice, misuse of power, marginalization and discrimination, served as key factors that led these individuals to identify and sympathize with radical ideology. The aim of this paper is to emphasize that, to develop effective preventative measures against recruitment into extremist groups, it is imperative to have a profound understanding of the social dynamics that make an individual susceptible to radicalization in the first place.
PubMed: 37287791
DOI: 10.3389/fpsyg.2023.1197282 -
Journal of Psychopathology and Clinical... Feb 2023Evolutionary models of depression posit that depressed mood represents an adaptive response to unacceptably low social status, motivating the inhibition of social...
Evolutionary models of depression posit that depressed mood represents an adaptive response to unacceptably low social status, motivating the inhibition of social risk-taking in favor of submissive behaviors which reduce the likelihood of social exclusion. We tested the hypothesis of reduced social risk taking using a novel adaptation of the Balloon Analogue Risk Task (BART) in participants with major depressive disorder (MDD; n = 27) and never-depressed comparison participants (n = 35). The BART requires participants to pump up virtual balloons. The more the balloon is pumped up, the more money a participant gains on that trial. However, more pumps also increase the risk the balloon will burst such that all money is lost. Prior to performing the BART, participants took part in a team induction in small groups in order to prime social-group membership. Participants then completed two conditions of the BART: an Individual condition where they risked only their own money, and a Social condition, where they risked the money of their social group. The groups did not differ in their performance in the individual condition (Cohen's d = 0.07). However, the MDD group risked fewer pumps in the Social condition than the never-depressed group (d = 0.57). The study supports the notion of an aversion to social risk-taking in depression. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
Topics: Humans; Decision Making; Depression; Depressive Disorder, Major; Risk-Taking; Affect
PubMed: 36808959
DOI: 10.1037/abn0000797 -
Frontiers in Human Neuroscience 2022A key emergent property of group social dynamic is synchrony-the coordination of actions, emotions, or physiological processes between group members. Despite this fact...
A key emergent property of group social dynamic is synchrony-the coordination of actions, emotions, or physiological processes between group members. Despite this fact and the inherent nested structure of groups, little research has assessed physiological synchronization between group members from a multi-level perspective, thus limiting a full understanding of the dynamics between members. To address this gap of knowledge we re-analyzed a large dataset ( = 261) comprising physiological and psychological data that were collected in two laboratory studies that involved two different social group tasks. In both studies, following the group task, members reported their experience of group cohesion via questionnaires. We utilized a non-linear analysis method-multidimensional recurrence quantification analysis that allowed us to represent physiological synchronization in cardiological interbeat intervals between group members at the individual-level and at the group-level. We found that across studies and their conditions, the change in physiological synchrony from baseline to group interaction predicted a psychological sense of group cohesion. This result was evident both at the individual and the group levels and was not modified by the context of the interaction. The individual- and group-level effects were highly correlated. These results indicate that the relationship between synchrony and cohesion is a multilayered construct. We re-affirm the role of physiological synchrony for cohesion in groups. Future studies are needed to crystallize our understanding of the differences and similarities between synchrony at the individual-level and synchrony at the group level to illuminate under which conditions one of these levels has primacy, or how they interact.
PubMed: 35903785
DOI: 10.3389/fnhum.2022.903407 -
Social Studies of Science Aug 2022This article maps the rise and fall of the idea of a (social) group across medicine in the context of contemporary analyses in psychology and sociology. This history...
This article maps the rise and fall of the idea of a (social) group across medicine in the context of contemporary analyses in psychology and sociology. This history shows the early 20th century emergence and growth of group medicine, group therapy and group comparisons. In recent decades, however, the idea that groups constituted the basic units of society has been replaced with the emergence of populations and systems that offer a more virtual and abstract context for individual relationships. This has implications for explanation itself as the demise of groups has changed the epistemological ground-rules for understanding identity formation and social change.
Topics: History, 20th Century; Knowledge; Social Change; Sociology
PubMed: 35635027
DOI: 10.1177/03063127221096389 -
Animals : An Open Access Journal From... Mar 2023In captivity, intact male horses, due to their sexual drive, are usually socially isolated from other horses. This lifestyle strongly contrasts with that experienced by... (Review)
Review
In captivity, intact male horses, due to their sexual drive, are usually socially isolated from other horses. This lifestyle strongly contrasts with that experienced by horses living in free-roaming, feral, or semi-feral conditions, where adult stallions have several roles in their social group, with successful reproduction being their primary drive. Reproductive skew in wild populations is high; many stallions will fail to reproduce at all, while others achieve high levels of reproductive success, siring a large number of foals. Successful stallions are those with particular characteristics and abilities that facilitate harem formation and tenure, allowing them to successfully take over a harem or establish a new one, protect mares from rival stallions, employ appropriate social behaviour to maintain group cohesion, and avoid kin-mating, for example through kin recognition mechanisms. Whilst the life of free-living stallions is far from stress-free, they retain ancestral adaptations to selection pressures (such as predation and competition) exhibited by their natural environment over thousands of years. Here, we discuss the challenges faced by free-living horse stallions, the roles they play in social groups, and their resulting social needs. By understanding these pressures and how stallions react to them, we highlighted the importance of the social environment for the stallion. It is hoped that a better understanding of wild stallions' lives will lead to their needs being more clearly met in captivity, reducing stereotypical behaviour and improving welfare.
PubMed: 37048406
DOI: 10.3390/ani13071151 -
Behavioral Ecology and Sociobiology 2021Parasites and their social hosts form many different relationships. But what kind of selection regimes are important? A look at the parameters that determine fitness of... (Review)
Review
Parasites and their social hosts form many different relationships. But what kind of selection regimes are important? A look at the parameters that determine fitness of the two parties suggests that social hosts differ from solitary ones primarily in the structure of transmission pathways. Because transmission is, both, the physical encounter of a new host and infecting it, several different elements determine parasite transmission success. These include spatial distance, genetic distance, or the temporal and ecological niche overlaps. Combing these elements into a 'generalized transmission distance' that determines parasite fitness aids in the identification of the critical steps. For example, short-distance transmission to genetically similar hosts within the social group is the most frequent process under sociality. Therefore, spatio-genetical distances are the main driver of parasite fitness. Vice versa, the generalized distance identifies the critical host defences. In this case, host defences should be primarily selected to defend against the within-group spread of an infection, especially among closely related group members.
PubMed: 34720348
DOI: 10.1007/s00265-021-03092-3 -
Science Advances May 2023Science is under attack and scientists are becoming more involved in efforts to defend it. The rise in science advocacy raises important questions regarding how science... (Review)
Review
Science is under attack and scientists are becoming more involved in efforts to defend it. The rise in science advocacy raises important questions regarding how science mobilization can both defend science and promote its use for the public good while also including the communities that benefit from science. This article begins with a discussion of the relevance of science advocacy. It then reviews research pointing to how scientists can sustain, diversify, and increase the political impact of their mobilization. Scientists, we argue, can build and maintain politically impactful coalitions by engaging with and addressing social group differences and diversity instead of suppressing them. The article concludes with a reflection on how the study of science-related mobilization would benefit from further research.
PubMed: 37205759
DOI: 10.1126/sciadv.abq4899