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Journal of Medical Internet Research May 2021Machine learning systems are part of the field of artificial intelligence that automatically learn models from data to make better decisions. Natural language processing... (Meta-Analysis)
Meta-Analysis Review
BACKGROUND
Machine learning systems are part of the field of artificial intelligence that automatically learn models from data to make better decisions. Natural language processing (NLP), by using corpora and learning approaches, provides good performance in statistical tasks, such as text classification or sentiment mining.
OBJECTIVE
The primary aim of this systematic review was to summarize and characterize, in methodological and technical terms, studies that used machine learning and NLP techniques for mental health. The secondary aim was to consider the potential use of these methods in mental health clinical practice.
METHODS
This systematic review follows the PRISMA (Preferred Reporting Items for Systematic Review and Meta-analysis) guidelines and is registered with PROSPERO (Prospective Register of Systematic Reviews; number CRD42019107376). The search was conducted using 4 medical databases (PubMed, Scopus, ScienceDirect, and PsycINFO) with the following keywords: machine learning, data mining, psychiatry, mental health, and mental disorder. The exclusion criteria were as follows: languages other than English, anonymization process, case studies, conference papers, and reviews. No limitations on publication dates were imposed.
RESULTS
A total of 327 articles were identified, of which 269 (82.3%) were excluded and 58 (17.7%) were included in the review. The results were organized through a qualitative perspective. Although studies had heterogeneous topics and methods, some themes emerged. Population studies could be grouped into 3 categories: patients included in medical databases, patients who came to the emergency room, and social media users. The main objectives were to extract symptoms, classify severity of illness, compare therapy effectiveness, provide psychopathological clues, and challenge the current nosography. Medical records and social media were the 2 major data sources. With regard to the methods used, preprocessing used the standard methods of NLP and unique identifier extraction dedicated to medical texts. Efficient classifiers were preferred rather than transparent functioning classifiers. Python was the most frequently used platform.
CONCLUSIONS
Machine learning and NLP models have been highly topical issues in medicine in recent years and may be considered a new paradigm in medical research. However, these processes tend to confirm clinical hypotheses rather than developing entirely new information, and only one major category of the population (ie, social media users) is an imprecise cohort. Moreover, some language-specific features can improve the performance of NLP methods, and their extension to other languages should be more closely investigated. However, machine learning and NLP techniques provide useful information from unexplored data (ie, patients' daily habits that are usually inaccessible to care providers). Before considering It as an additional tool of mental health care, ethical issues remain and should be discussed in a timely manner. Machine learning and NLP methods may offer multiple perspectives in mental health research but should also be considered as tools to support clinical practice.
Topics: Artificial Intelligence; Data Management; Humans; Machine Learning; Mental Health; Natural Language Processing
PubMed: 33944788
DOI: 10.2196/15708 -
Orthodontics & Craniofacial Research Dec 2021This scoping review aims to determine the applications of Artificial Intelligence (AI) that are extensively employed in the field of Orthodontics, to evaluate its... (Review)
Review
OBJECTIVE
This scoping review aims to determine the applications of Artificial Intelligence (AI) that are extensively employed in the field of Orthodontics, to evaluate its benefits, and to discuss its potential implications in this speciality. Recent decades have witnessed enormous changes in our profession. The arrival of new and more aesthetic options in orthodontic treatment, the transition to a fully digital workflow, the emergence of temporary anchorage devices and new imaging methods all provide both patients and professionals with a new focus in orthodontic care.
MATERIALS AND METHODS
This review was performed following the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) guidelines. The electronic literature search was performed through MEDLINE/PubMed, Scopus, Web of Science, Cochrane and IEEE Xplore databases with a 11-year time restriction: January 2010 till March 2021. No additional manual searches were performed.
RESULTS
The electronic literature search initially returned 311 records, and 115 after removing duplicate references. Finally, the application of the inclusion criteria resulted in 17 eligible publications in the qualitative synthesis review.
CONCLUSION
The analysed studies demonstrated that Convolution Neural Networks can be used for the automatic detection of anatomical reference points on radiological images. In the growth and development research area, the Cervical Vertebral Maturation stage can be determined using an Artificial Neural Network model and obtain the same results as expert human observers. AI technology can also improve the diagnostic accuracy for orthodontic treatments, thereby helping the orthodontist work more accurately and efficiently.
Topics: Artificial Intelligence; Esthetics, Dental; Humans; Orthodontics
PubMed: 34270881
DOI: 10.1111/ocr.12517 -
Journal of Medical Internet Research Nov 2023Anxiety disorders rank among the most prevalent mental disorders worldwide. Anxiety symptoms are typically evaluated using self-assessment surveys or interview-based... (Meta-Analysis)
Meta-Analysis Review
BACKGROUND
Anxiety disorders rank among the most prevalent mental disorders worldwide. Anxiety symptoms are typically evaluated using self-assessment surveys or interview-based assessment methods conducted by clinicians, which can be subjective, time-consuming, and challenging to repeat. Therefore, there is an increasing demand for using technologies capable of providing objective and early detection of anxiety. Wearable artificial intelligence (AI), the combination of AI technology and wearable devices, has been widely used to detect and predict anxiety disorders automatically, objectively, and more efficiently.
OBJECTIVE
This systematic review and meta-analysis aims to assess the performance of wearable AI in detecting and predicting anxiety.
METHODS
Relevant studies were retrieved by searching 8 electronic databases and backward and forward reference list checking. In total, 2 reviewers independently carried out study selection, data extraction, and risk-of-bias assessment. The included studies were assessed for risk of bias using a modified version of the Quality Assessment of Diagnostic Accuracy Studies-Revised. Evidence was synthesized using a narrative (ie, text and tables) and statistical (ie, meta-analysis) approach as appropriate.
RESULTS
Of the 918 records identified, 21 (2.3%) were included in this review. A meta-analysis of results from 81% (17/21) of the studies revealed a pooled mean accuracy of 0.82 (95% CI 0.71-0.89). Meta-analyses of results from 48% (10/21) of the studies showed a pooled mean sensitivity of 0.79 (95% CI 0.57-0.91) and a pooled mean specificity of 0.92 (95% CI 0.68-0.98). Subgroup analyses demonstrated that the performance of wearable AI was not moderated by algorithms, aims of AI, wearable devices used, status of wearable devices, data types, data sources, reference standards, and validation methods.
CONCLUSIONS
Although wearable AI has the potential to detect anxiety, it is not yet advanced enough for clinical use. Until further evidence shows an ideal performance of wearable AI, it should be used along with other clinical assessments. Wearable device companies need to develop devices that can promptly detect anxiety and identify specific time points during the day when anxiety levels are high. Further research is needed to differentiate types of anxiety, compare the performance of different wearable devices, and investigate the impact of the combination of wearable device data and neuroimaging data on the performance of wearable AI.
TRIAL REGISTRATION
PROSPERO CRD42023387560; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=387560.
Topics: Humans; Artificial Intelligence; Anxiety; Anxiety Disorders; Algorithms; Databases, Factual
PubMed: 37938883
DOI: 10.2196/48754 -
Artificial Organs Sep 2022This review aims to systematically evaluate the currently available evidence investigating the use of artificial intelligence (AI) and machine learning (ML) in the field... (Review)
Review
BACKGROUND
This review aims to systematically evaluate the currently available evidence investigating the use of artificial intelligence (AI) and machine learning (ML) in the field of cardiac transplantation. Furthermore, based on the challenges identified we aim to provide a series of recommendations and a knowledge base for future research in the field of ML and heart transplantation.
METHODS
A systematic database search was conducted of original articles that explored the use of ML and/or AI in heart transplantation in EMBASE, MEDLINE, Cochrane database, and Google Scholar, from inception to November 2021.
RESULTS
Our search yielded 237 articles, of which 13 studies were included in this review, featuring 463 850 patients. Three main areas of application were identified: (1) ML for predictive modeling of heart transplantation mortality outcomes; (2) ML in graft failure outcomes; (3) ML to aid imaging in heart transplantation. The results of the included studies suggest that AI and ML are more accurate in predicting graft failure and mortality than traditional scoring systems and conventional regression analysis. Major predictors of graft failure and mortality identified in ML models were: length of hospital stay, immunosuppressive regimen, recipient's age, congenital heart disease, and organ ischemia time. Other potential benefits include analyzing initial lab investigations and imaging, assisting a patient with medication adherence, and creating positive behavioral changes to minimize further cardiovascular risk.
CONCLUSION
ML demonstrated promising applications for improving heart transplantation outcomes and patient-centered care, nevertheless, there remain important limitations relating to implementing AI into everyday surgical practices.
Topics: Artificial Intelligence; Databases, Factual; Heart Transplantation; Humans; Length of Stay; Machine Learning
PubMed: 35719121
DOI: 10.1111/aor.14334 -
International Journal of Environmental... Oct 2021Chronic Low Back Pain (LBP) is a symptom that may be caused by several diseases, and it is currently the leading cause of disability worldwide. The increased amount of... (Review)
Review
Chronic Low Back Pain (LBP) is a symptom that may be caused by several diseases, and it is currently the leading cause of disability worldwide. The increased amount of digital images in orthopaedics has led to the development of methods related to artificial intelligence, and to computer vision in particular, which aim to improve diagnosis and treatment of LBP. In this manuscript, we have systematically reviewed the available literature on the use of computer vision in the diagnosis and treatment of LBP. A systematic research of PubMed electronic database was performed. The search strategy was set as the combinations of the following keywords: "Artificial Intelligence", "Feature Extraction", "Segmentation", "Computer Vision", "Machine Learning", "Deep Learning", "Neural Network", "Low Back Pain", "Lumbar". Results: The search returned a total of 558 articles. After careful evaluation of the abstracts, 358 were excluded, whereas 124 papers were excluded after full-text examination, taking the number of eligible articles to 76. The main applications of computer vision in LBP include feature extraction and segmentation, which are usually followed by further tasks. Most recent methods use deep learning models rather than digital image processing techniques. The best performing methods for segmentation of vertebrae, intervertebral discs, spinal canal and lumbar muscles achieve Sørensen-Dice scores greater than 90%, whereas studies focusing on localization and identification of structures collectively showed an accuracy greater than 80%. Future advances in artificial intelligence are expected to increase systems' autonomy and reliability, thus providing even more effective tools for the diagnosis and treatment of LBP.
Topics: Artificial Intelligence; Computers; Humans; Intervertebral Disc; Low Back Pain; Reproducibility of Results
PubMed: 34682647
DOI: 10.3390/ijerph182010909 -
Journal of Digital Imaging Jun 2023Using computer vision through artificial intelligence (AI) is one of the main technological advances in dentistry. However, the existing literature on the practical... (Meta-Analysis)
Meta-Analysis Review
Using computer vision through artificial intelligence (AI) is one of the main technological advances in dentistry. However, the existing literature on the practical application of AI for detecting cephalometric landmarks of orthodontic interest in digital images is heterogeneous, and there is no consensus regarding accuracy and precision. Thus, this review evaluated the use of artificial intelligence for detecting cephalometric landmarks in digital imaging examinations and compared it to manual annotation of landmarks. An electronic search was performed in nine databases to find studies that analyzed the detection of cephalometric landmarks in digital imaging examinations with AI and manual landmarking. Two reviewers selected the studies, extracted the data, and assessed the risk of bias using QUADAS-2. Random-effects meta-analyses determined the agreement and precision of AI compared to manual detection at a 95% confidence interval. The electronic search located 7410 studies, of which 40 were included. Only three studies presented a low risk of bias for all domains evaluated. The meta-analysis showed AI agreement rates of 79% (95% CI: 76-82%, I = 99%) and 90% (95% CI: 87-92%, I = 99%) for the thresholds of 2 and 3 mm, respectively, with a mean divergence of 2.05 (95% CI: 1.41-2.69, I = 10%) compared to manual landmarking. The menton cephalometric landmark showed the lowest divergence between both methods (SMD, 1.17; 95% CI, 0.82; 1.53; I = 0%). Based on very low certainty of evidence, the application of AI was promising for automatically detecting cephalometric landmarks, but further studies should focus on testing its strength and validity in different samples.
Topics: Humans; Artificial Intelligence; Algorithms; Reproducibility of Results; Cephalometry; Electronic Data Processing
PubMed: 36604364
DOI: 10.1007/s10278-022-00766-w -
Journal of Cutaneous Pathology Sep 2023Frozen sections are a useful pathologic tool, but variable image quality may impede the use of artificial intelligence and machine learning in their interpretation. We... (Review)
Review
Frozen sections are a useful pathologic tool, but variable image quality may impede the use of artificial intelligence and machine learning in their interpretation. We aimed to identify the current research on machine learning models trained or tested on frozen section images. We searched PubMed and Web of Science for articles presenting new machine learning models published in any year. Eighteen papers met all inclusion criteria. All papers presented at least one novel model trained or tested on frozen section images. Overall, convolutional neural networks tended to have the best performance. When physicians were able to view the output of the model, they tended to perform better than either the model or physicians alone at the tested task. Models trained on frozen sections performed well when tested on other slide preparations, but models trained on only formalin-fixed tissue performed significantly worse across other modalities. This suggests not only that machine learning can be applied to frozen section image processing, but also use of frozen section images may increase model generalizability. Additionally, expert physicians working in concert with artificial intelligence may be the future of frozen section histopathology.
Topics: Humans; Artificial Intelligence; Frozen Sections; Neural Networks, Computer; Machine Learning
PubMed: 37394789
DOI: 10.1111/cup.14481 -
International Journal of Environmental... May 2022Low Back Pain (LBP) is currently the first cause of disability in the world, with a significant socioeconomic burden. Diagnosis and treatment of LBP often involve a... (Review)
Review
Low Back Pain (LBP) is currently the first cause of disability in the world, with a significant socioeconomic burden. Diagnosis and treatment of LBP often involve a multidisciplinary, individualized approach consisting of several outcome measures and imaging data along with emerging technologies. The increased amount of data generated in this process has led to the development of methods related to artificial intelligence (AI), and to computer-aided diagnosis (CAD) in particular, which aim to assist and improve the diagnosis and treatment of LBP. In this manuscript, we have systematically reviewed the available literature on the use of CAD in the diagnosis and treatment of chronic LBP. A systematic research of PubMed, Scopus, and Web of Science electronic databases was performed. The search strategy was set as the combinations of the following keywords: “Artificial Intelligence”, “Machine Learning”, “Deep Learning”, “Neural Network”, “Computer Aided Diagnosis”, “Low Back Pain”, “Lumbar”, “Intervertebral Disc Degeneration”, “Spine Surgery”, etc. The search returned a total of 1536 articles. After duplication removal and evaluation of the abstracts, 1386 were excluded, whereas 93 papers were excluded after full-text examination, taking the number of eligible articles to 57. The main applications of CAD in LBP included classification and regression. Classification is used to identify or categorize a disease, whereas regression is used to produce a numerical output as a quantitative evaluation of some measure. The best performing systems were developed to diagnose degenerative changes of the spine from imaging data, with average accuracy rates >80%. However, notable outcomes were also reported for CAD tools executing different tasks including analysis of clinical, biomechanical, electrophysiological, and functional imaging data. Further studies are needed to better define the role of CAD in LBP care.
Topics: Artificial Intelligence; Computers; Diagnosis, Computer-Assisted; Humans; Intervertebral Disc Degeneration; Low Back Pain
PubMed: 35627508
DOI: 10.3390/ijerph19105971 -
International Journal of Environmental... Aug 2020Suicide is a leading cause of death that defies prediction and challenges prevention efforts worldwide. Artificial intelligence (AI) and machine learning (ML) have...
Suicide is a leading cause of death that defies prediction and challenges prevention efforts worldwide. Artificial intelligence (AI) and machine learning (ML) have emerged as a means of investigating large datasets to enhance risk detection. A systematic review of ML investigations evaluating suicidal behaviors was conducted using PubMed/MEDLINE, PsychInfo, Web-of-Science, and EMBASE, employing search strings and MeSH terms relevant to suicide and AI. Databases were supplemented by hand-search techniques and Google Scholar. Inclusion criteria: (1) journal article, available in English, (2) original investigation, (3) employment of AI/ML, (4) evaluation of a suicide risk outcome. N = 594 records were identified based on abstract search, and 25 hand-searched reports. N = 461 reports remained after duplicates were removed, n = 316 were excluded after abstract screening. Of n = 149 full-text articles assessed for eligibility, n = 87 were included for quantitative synthesis, grouped according to suicide behavior outcome. Reports varied widely in methodology and outcomes. Results suggest high levels of risk classification accuracy (>90%) and Area Under the Curve (AUC) in the prediction of suicidal behaviors. We report key findings and central limitations in the use of AI/ML frameworks to guide additional research, which hold the potential to impact suicide on broad scale.
Topics: Artificial Intelligence; Humans; Machine Learning; Risk Assessment; Suicidal Ideation; Suicide Prevention
PubMed: 32824149
DOI: 10.3390/ijerph17165929 -
Environmental Science and Pollution... Jun 2023As clean water can be considered among the essentials of human life, there is always a requirement to seek its foremost and high quality. Water primarily becomes...
As clean water can be considered among the essentials of human life, there is always a requirement to seek its foremost and high quality. Water primarily becomes polluted due to organic as well as inorganic pollutants, including nutrients, heavy metals, and constant contamination with organic materials. Predicting the quality of water accurately is essential for its better management along with controlling pollution. With stricter laws regarding water treatment to remove organic and biologic materials along with different pollutants, looking for novel technologic procedures will be necessary for improved control of the treatment processes by water utilities. Linear regression-based models with relative simplicity considering water prediction have been typically used as available statistical models. Nevertheless, in a majority of real problems, particularly those associated with modeling of water quality, non-linear patterns will be observed, requiring non-linear models to address them. Thus, artificial intelligence (AI) can be a good candidate in modeling and optimizing the elimination of pollutants from water in empirical settings with the ability to generate ideal operational variables, due to its recent considerable advancements. Management and operation of water treatment procedures are supported technically by these technologies, leading to higher efficiency compared to sole dependence on human operations. Thus, establishing predictive models for water quality and subsequently, more efficient management of water resources would be critically important, serving as a strong tool. A systematic review methodology has been employed in the present work to investigate the previous studies over the time interval of 2010-2020, while analyzing and synthesizing the literature, particularly regarding AI application in water treatment. A total number of 92 articles had addressed the topic under study using AI. Based on the conclusions, the application of AI can obviously facilitate operations, process automation, and management of water resources in significantly volatile contexts.
Topics: Humans; Artificial Intelligence; Water Purification; Water Quality; Models, Statistical; Environmental Pollutants
PubMed: 34609681
DOI: 10.1007/s11356-021-16471-0