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Developmental Cognitive Neuroscience Dec 2023Rhythmic visual stimulation (RVS), the periodic presentation of visual stimuli to elicit a rhythmic brain response, is increasingly applied to reveal insights into early... (Review)
Review
Rhythmic visual stimulation (RVS), the periodic presentation of visual stimuli to elicit a rhythmic brain response, is increasingly applied to reveal insights into early neurocognitive development. Our systematic review identified 69 studies applying RVS in 0- to 6-year-olds. RVS has long been used to study the development of the visual system and applications have more recently been expanded to uncover higher cognitive functions in the developing brain, including overt and covert attention, face and object perception, numeral cognition, and predictive processing. These insights are owed to the unique benefits of RVS, such as the targeted frequency and stimulus-specific neural responses, as well as a remarkable signal-to-noise ratio. Yet, neural mechanisms underlying the RVS response are still poorly understood. We discuss critical challenges and avenues for future research, and the unique potentials the method holds. With this review, we provide a resource for researchers interested in the breadth of developmental RVS research and hope to inspire the future use of this cutting-edge method in developmental cognitive neuroscience.
Topics: Humans; Child; Electroencephalography; Photic Stimulation; Evoked Potentials, Visual; Brain; Attention; Visual Perception
PubMed: 37948945
DOI: 10.1016/j.dcn.2023.101315 -
The British Journal of Ophthalmology Jul 2014Retinal implants present an innovative way of restoring sight in degenerative retinal diseases. Previous reviews of research progress were written by groups developing... (Comparative Study)
Comparative Study Review
Retinal implants present an innovative way of restoring sight in degenerative retinal diseases. Previous reviews of research progress were written by groups developing their own devices. This systematic review objectively compares selected models by examining publications describing five representative retinal prostheses: Argus II, Boston Retinal Implant Project, Epi-Ret 3, Intelligent Medical Implants (IMI) and Alpha-IMS (Retina Implant AG). Publications were analysed using three criteria for interim success: clinical availability, vision restoration potential and long-term biocompatibility. Clinical availability: Argus II is the only device with FDA approval. Argus II and Alpha-IMS have both received the European CE Marking. All others are in clinical trials, except the Boston Retinal Implant, which is in animal studies. Vision restoration: resolution theoretically correlates with electrode number. Among devices with external cameras, the Boston Retinal Implant leads with 100 electrodes, followed by Argus II with 60 electrodes and visual acuity of 20/1262. Instead of an external camera, Alpha-IMS uses a photodiode system dependent on natural eye movements and can deliver visual acuity up to 20/546. Long-term compatibility: IMI offers iterative learning; Epi-Ret 3 is a fully intraocular device; Alpha-IMS uses intraocular photosensitive elements. Merging the results of these three criteria, Alpha-IMS is the most likely to achieve long-term success decades later, beyond current clinical availability.
Topics: Biocompatible Materials; Electrodes, Implanted; Humans; Prosthesis Implantation; Retinal Degeneration; Vision Disorders; Visual Acuity; Visual Prosthesis
PubMed: 24403565
DOI: 10.1136/bjophthalmol-2013-303708 -
Neuroscience and Biobehavioral Reviews Dec 2020The occurrence of implicit processing of visual stimuli during inattentional blindness is still a matter of debate. To assess the evidence available in this debate, we... (Meta-Analysis)
Meta-Analysis Review
The occurrence of implicit processing of visual stimuli during inattentional blindness is still a matter of debate. To assess the evidence available in this debate, we conducted a systematic review of articles that explored whether unexpected visual stimuli presented during inattentional blindness are implicitly processed despite not being reported. Additionally, we employed meta-analysis to combine 59 behavioral experiments and investigate the statistical support for such implicit processing across experiments. Results showed that visual stimuli can be processed when unattended and unnoticed. Additionally, we reviewed the measures used to assess participants' awareness of the unexpected stimuli. We also employed meta-analysis to search for differences in awareness of the unexpected stimuli that may result from adopting distinct criteria to categorize participants as aware or unaware. The results showed that the overall effect of awareness changed depending on whether more demanding or less demanding measures of awareness were employed. This suggests that the choice of awareness measure may influence conclusions about whether processing of the US is implicit or explicit. We discuss the implications of these results for the study of implicit processing and the role of attention in visual cognition.
Topics: Attention; Awareness; Blindness; Cognition; Humans; Visual Perception
PubMed: 33086130
DOI: 10.1016/j.neubiorev.2020.10.005 -
JAMA Psychiatry Oct 2023Face processing is foundational to human social cognition, is central to the hallmark features of autism spectrum disorder (ASD), and shapes neural systems and social... (Meta-Analysis)
Meta-Analysis
IMPORTANCE
Face processing is foundational to human social cognition, is central to the hallmark features of autism spectrum disorder (ASD), and shapes neural systems and social behavior. Highly efficient and specialized, the face processing system is sensitive to inversion, demonstrated by reduced accuracy in recognition and altered neural response to inverted faces. Understanding at which mechanistic level the autistic face processing system may be particularly different, as measured by the face inversion effect, will improve overall understanding of brain functioning in autism.
OBJECTIVE
To synthesize data from the extant literature to determine differences of the face processing system in ASD, as measured by the face inversion effect, across multiple mechanistic levels.
DATA SOURCES
Systematic searches were conducted in the MEDLINE, Embase, Web of Science, and PubMed databases from inception to August 11, 2022.
STUDY SELECTION
Original research that reported performance-based measures of face recognition to upright and inverted faces in ASD and neurotypical samples were included for quantitative synthesis. All studies were screened by at least 2 reviewers.
DATA EXTRACTION AND SYNTHESIS
This systematic review and meta-analysis was conducted according to the 2020 Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) reporting guideline. Multiple effect sizes were extracted from studies to maximize information gain and statistical precision and used a random-effects, multilevel modeling framework to account for statistical dependencies within study samples.
MAIN OUTCOMES AND MEASURES
Effect sizes were calculated as a standardized mean change score between ASD and neurotypical samples (ie, Hedges g). The primary outcome measure was performance difference between upright and inverted faces during face recognition tasks. Measurement modality, psychological construct, recognition demand, sample age, sample sex distribution, and study quality assessment scores were assessed as moderators.
RESULTS
Of 1768 screened articles, 122 effect sizes from 38 empirical articles representing data from 1764 individual participants (899 ASD individuals and 865 neurotypical individuals) were included in the meta-analysis. Overall, face recognition performance differences between upright and inverted faces were reduced in autistic individuals compared with neurotypical individuals (g = -0.41; SE = 0.11; 95% credible interval [CrI], -0.63 to -0.18). However, there was considerable heterogeneity among effect sizes, which were explored with moderator analysis. The attenuated face inversion effect in autistic individuals was more prominent in emotion compared with identity recognition (b = 0.46; SE = 0.26; 95% CrI, -0.08 to 0.95) and in behavioral compared with electrophysiological measures (b = 0.23; SE = 0.24; 95% CrI, -0.25 to 0.70).
CONCLUSIONS AND RELEVANCE
This study found that on average, face recognition in autism is less impacted by inversion. These findings suggest less specialization or expertise of the face processing system in autism, particularly in recognizing emotion from faces as measured in behavioral paradigms.
Topics: Humans; Autistic Disorder; Facial Recognition; Autism Spectrum Disorder; Bayes Theorem; Brain
PubMed: 37405787
DOI: 10.1001/jamapsychiatry.2023.2105 -
Journal of the American Academy of... 2008It is reasonable to expect that deaf individuals require the use of vision for purposes other than those needed by hearing persons. For example, without the use of... (Review)
Review
BACKGROUND
It is reasonable to expect that deaf individuals require the use of vision for purposes other than those needed by hearing persons. For example, without the use of hearing, one would need to scan the environment visually to determine if someone was approaching rather than listening for footsteps or a name being called. Furthermore, these experiential differences could alter the development of neural organization of sensory systems of deaf persons.
PURPOSE
To review the evidence-based literature in the area of visual attention and deafness with an emphasis on a series of visual attention studies utilizing several paradigms including the Continuous Performance Task, the Letter Cancellation Task, the Flanker Task, and a self-designed task of target identification in the periphery under distracter and nondistracter conditions conducted at Vanderbilt University.
RESEARCH DESIGN
Systematic review.
RESULTS
Collectively, the Vanderbilt studies pointed to a compensatory role that the visual system plays for deaf individuals. Specifically, the visual system appears to play an important role in directing a deaf individual's attention to the near visual periphery.
CONCLUSIONS
Studies of visual attention in deaf individuals have been mixed in their conclusions about whether altered neural organization results in better or worse visual attention abilities by those who are deaf relative to those with normal hearing. The notion of across-the-board deficits or enhancements in the visual function of deaf individuals is not supported by the literature, nor is there support for the idea that fundamental visual sensory abilities such as acuity or light detection differ between deaf and hearing persons.
Topics: Adaptation, Psychological; Attention; Deafness; Evidence-Based Medicine; Humans; Task Performance and Analysis; Visual Perception
PubMed: 19358454
DOI: 10.3766/jaaa.19.10.2 -
Schizophrenia Research Dec 2017Patients with schizophrenia show impairments in processing of biological motion. This is especially important since deficits in domains of social cognition has been... (Meta-Analysis)
Meta-Analysis Review
CONTEXT
Patients with schizophrenia show impairments in processing of biological motion. This is especially important since deficits in domains of social cognition has been associated with functional outcome and everyday functioning in this population.
OBJECTIVES
We conducted a systematic review and meta-analysis of studies which have used point-light displays to present whole-body motion to patients with schizophrenia and healthy controls, to evaluate the magnitude of differences between these groups in biological motion processing.
METHOD
Firstly, relevant publications were identified by a systematic search of Google Scholar and PubMed databases. Secondly, we excluded non-relevant studies for the meta-analysis according to our exclusion criteria. Effect sizes were expressed as standardized mean difference (SMD).
RESULTS
15 papers reporting results of 14 different experiments with 571 patients and 482 controls were included in the meta-analysis. The results for the general biological motion perception analysis revealed that patients with schizophrenia (compared with healthy controls) present reduced biological motion processing capacity with the effect size (SMD) of 0.66 (95% CI, -0.79 to -0.54; p<0.001). The results for the specific biological motion-based tasks were also statistically significant with SMD of 0.72 for Basic Biological Motion task (95% CI: -0.94 to -0.51; p<0.001) and SMD of 0.61 for Emotion in Biological Motion task, (95% CI: -0.79 to -0.43; p<0.001) respectively.
CONCLUSION
The findings from our meta-analysis highlight abnormalities in general and specific domains of biological motion perception in schizophrenia patients as compared with healthy controls.
Topics: Humans; Motion Perception; Perceptual Disorders; Schizophrenic Psychology; Social Perception
PubMed: 28285029
DOI: 10.1016/j.schres.2017.03.013 -
Journal of Cataract and Refractive... Nov 2023The main aim of this systematic review and meta-analysis was to evaluate the safety and efficacy profile of immediate sequential bilateral cataract surgery (ISBCS)... (Meta-Analysis)
Meta-Analysis
The main aim of this systematic review and meta-analysis was to evaluate the safety and efficacy profile of immediate sequential bilateral cataract surgery (ISBCS) compared with delayed sequential bilateral cataract surgery (DSBCS). MEDLINE Ovid, EMBASE, and CENTRAL databases were searched. Outcome measures were postoperative visual acuity, postoperative spherical equivalent (refractive outcome), endophthalmitis, corneal edema, pseudophakic macular edema, and posterior capsule rupture (PCR). 13 articles met criteria for final inclusion. A total of 11 068 622 participants (18 802 043 eyes) were included. No statistically significant differences between ISBCS and DSBCS were identified in all the postoperative outcomes evaluated. However, a higher risk for PCR was identified in the ISBCS group from the pooled analysis of nonrandomized studies (risk ratio, 1.34, 95% CI, 1.08-1.67, P = .0081). In our view, the ISBCS approach has an acceptable safety-efficacy profile, comparable with DSBCS. Future investigations are warranted, with a focus on the analysis of risk factors for surgical complications, patient-reported outcome-measures, and cost effectiveness.
Topics: Humans; Phacoemulsification; Cataract Extraction; Cataract; Visual Acuity; Ophthalmology
PubMed: 37276258
DOI: 10.1097/j.jcrs.0000000000001230 -
Retina (Philadelphia, Pa.) Oct 2023The mean change in best-corrected visual acuity (BCVA), intraocular pressure, and endothelial cell counts after intraocular lens (IOL) implantation and the incidence... (Meta-Analysis)
Meta-Analysis
PURPOSE
The mean change in best-corrected visual acuity (BCVA), intraocular pressure, and endothelial cell counts after intraocular lens (IOL) implantation and the incidence rate of postoperative complications were estimated by systematic review and meta-analysis to assess the surgical and refractive outcomes of the sutureless scleral fixation Carlevale IOL.
METHODS
A literature search was conducted using PubMed, Embase, and Scopus. The weighted mean difference (WMD) was used to present the mean change in BCVA, intraocular pressure, and endothelial cell count after IOL implantation, whereas a proportional meta-analysis was used to estimate the pooled incidence rate of postoperative complications.
RESULTS
In the meta-analysis of 13 studies involving 550 eyes, the pooled WMD of the mean change in BCVA showed a significant improvement in BCVA in patients who underwent Carlevale IOL implantation (WMD = 0.38, 95% confidence interval: 0.30-0.46, P < 0.001; heterogeneity [I 2 ] = 52.02%). The subgroup analyses indicated that the mean change in BCVA was not significantly higher according to the last follow-up visit, with no statistically significant subgroup effect ( P = 0.21) (WMD up to 6 months: 0.34, 95% confidence interval: 0.23-0.45, I 2 = 58.32%, WMD up to 24 months: 0.42, 95% confidence interval: 0.34-0.51, I 2 = 38.08%). In the meta-analysis of 16 studies involving 608 eyes, the pooled incidence rate of postoperative complications was equal to 0.22 (95% confidence interval: 0.13-0.32, I 2 = 84.87, P ≤ 0.001).
CONCLUSION
Carlevale IOL implantation represents a reliable method of restoring vision in eyes with missing capsular or zonular support.
Topics: Humans; Lens Implantation, Intraocular; Visual Acuity; Lenses, Intraocular; Refraction, Ocular; Sclera; Postoperative Complications; Retrospective Studies; Suture Techniques
PubMed: 37399540
DOI: 10.1097/IAE.0000000000003873 -
Telemedicine Journal and E-health : the... Jun 2024(Review)
Review
Topics: Humans; Internet; Mobile Applications; Telemedicine; Vision Tests; Visual Acuity
PubMed: 38564179
DOI: 10.1089/tmj.2023.0368 -
Retina (Philadelphia, Pa.) Oct 2014To systematically review the influence of the lag time between macula-off retinal detachment and surgical intervention on postoperative visual acuity as main outcome... (Meta-Analysis)
Meta-Analysis Review
PURPOSE
To systematically review the influence of the lag time between macula-off retinal detachment and surgical intervention on postoperative visual acuity as main outcome measure.
METHODS
Systematic review and meta-analysis of articles published from 1995 to October 2013 of patients with macula-off retinal detachment and treated with scleral buckling or pars plana vitrectomy. Eligible data were pooled in a meta-analysis, analyzing the odds ratio between different durations of ≤ 3, ≤ 4, ≤ 7, and ≤ 10 days, comparing a final visual acuity of ≤ 0.4 logMAR with >0.4 logMAR, using a random-effects model. Last, the number needed to treat was calculated.
RESULTS
Fourteen articles were eligible, of which 9 studies contained data that were suitable for meta-analysis. Patients who were operated with scleral buckling (n = 602) within 3 days since macular detachment had a statistically significant better chance of reaching a final visual acuity of 0.4 logMAR or better compared with a longer duration of macular detachment, with an odds ratio for ≤ 3 days versus 4 days to 7 days of 2.86 (95% confidence interval, 1.37-5.99) and an odds ratio for ≤ 3 days versus >3 days of 3.09 (95% confidence interval, 1.56-6.12), and with a number needed to treat of 4. For pars plana vitrectomy, the limited amount of data precluded a meta-analysis with substantial results.
CONCLUSION
This meta-analysis suggests that scleral buckling for macular detachment must preferably be performed within 3 days to optimize visual outcome.
Topics: Humans; Macula Lutea; Retinal Detachment; Scleral Buckling; Time Factors; Visual Acuity; Vitrectomy
PubMed: 25121930
DOI: 10.1097/IAE.0000000000000296